Anti-Fibrotic Effects of Class I HDAC Inhibitor, Mocetinostat Is Associated with IL-6/Stat3 Signaling in Ischemic Heart Failure

Reduced phosphorylation of Stat3 at Ser-727 mediated by casein kinase 2 — Protein phosphatase 2A enhances Stat3 Tyr-705 induced tumorigenic potential of glioma cells

(2014) Tapashi Mandal et al.   CELLULAR SIGNALLING

Histone Deacetylase Inhibitors Modulate Interleukin 6-dependent CD4+T Cell Polarizationin Vitroandin Vivo

(2014) Rainer Glauben et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Class I HDACs regulate angiotensin II-dependent cardiac fibrosis via fibroblasts and circulating fibrocytes

(2014) Sarah M. Williams et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Histone deacetylase inhibition improved cardiac functions with direct antifibrotic activity in heart failure

(2013) Yu-Hsun Kao et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Inhibition of Histone Deacetylase-induced Myocardial Repair Is Mediated by c-kit in Infarcted Hearts

(2012) Ling Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Macrophage-Stimulated Cardiac Fibroblast Production of IL-6 Is Essential for TGF β/Smad Activation and Cardiac Fibrosis Induced by Angiotensin II

(2012) Feifei Ma et al.   PLoS One

Inhibition of Signal Transducer and Activator of Transcription 3 (STAT3) Attenuates Interleukin-6 (IL-6)-induced Collagen Synthesis and Resultant Hypertrophy in Rat Heart

(2011) Saiful Anam Mir et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rapid quantification of myocardial fibrosis: a new macro-based automated analysis

(2011) Awal M. Hadi et al.   CELLULAR ONCOLOGY

Antifibrotic activity of an inhibitor of histone deacetylases in DOCA-salt hypertensive rats

(2010) Abishek Iyer et al.   BRITISH JOURNAL OF PHARMACOLOGY

Transplantation of cardiac progenitor cell sheet onto infarcted heart promotes cardiogenesis and improves function

(2010) Liudmila Zakharova et al.   CARDIOVASCULAR RESEARCH

Continuous Glycoprotein-130–Mediated Signal Transducer and Activator of Transcription-3 Activation Promotes Inflammation, Left Ventricular Rupture, and Adverse Outcome in Subacute Myocardial Infarction

(2010) Denise Hilfiker-Kleiner et al.   CIRCULATION

Interleukin 6 Mediates Myocardial Fibrosis, Concentric Hypertrophy, and Diastolic Dysfunction in Rats

(2010) Giselle C. Meléndez et al.   HYPERTENSION

Leptin Signaling in the Failing and Mechanically Unloaded Human Heart

(2009) Kenneth R. McGaffin et al.   Circulation-Heart Failure

Myocardial remodeling after infarction: the role of myofibroblasts

(2009) Susanne W. M. van den Borne et al.   Nature Reviews Cardiology

Cardiac fibroblasts: At the heart of myocardial remodeling

(2009) Karen E. Porter et al.   PHARMACOLOGY & THERAPEUTICS

Connective tissue growth factor and cardiac fibrosis

(2008) A. Daniels et al.   Acta Physiologica

Inhibitors of histone deacetylase (HDAC) restore the p53 pathway in neuroblastoma cells

(2007) F Condorelli et al.   BRITISH JOURNAL OF PHARMACOLOGY