Article
Materials Science, Coatings & Films
Juyi Yang, Yanbin Zhao, Jianwei Dai, Linyuan Han, Qiangsheng Dong, Lu Zhang, Jing Bai, Feng Xue, Paul K. Chu, Chenglin Chu
Summary: In this study, a polyethyleneimine/polyacrylic acid (PEI/PAA) multilayered coating is prepared by layer-by-layer (LbL) assembly on the WE43 Mg alloy, followed by mineralization of hydroxyapatite (HA) on the LbL multilayer. The composite coating with a compact surface shows improved corrosion resistance. The formation mechanism, structure, and properties of the organic/inorganic composite coating are investigated systematically.
SURFACE & COATINGS TECHNOLOGY
(2023)
Article
Chemistry, Applied
Qingyun Fu, Mingcheng Feng, Jian Li, Nian He, Wenjing Li, Jingyao Li, Junjie Yang, Weihong Jin, Wei Li, Zhentao Yu
Summary: Magnesium and its alloys have potential as temporary biomedical implants, but their rapid degradation and cytotoxicity hinder clinical use. Hydroxyapatite coatings can enhance corrosion resistance and biocompatibility. This study investigates the effects of synthetic solution concentrations on coating morphology, corrosion protection, and cytocompatibility.
JOURNAL OF COATINGS TECHNOLOGY AND RESEARCH
(2022)
Article
Chemistry, Physical
Jinxing Cao, Xin Liu, Xiaohong Jiang, Ruizhe Lian, Bin Du, Aleksandr Rogachev
Summary: The study fabricated bioactive films containing magnesium particles using pulsed laser deposition, which exhibited excellent drug release performance in simulated body fluids. A sustained-release effect was verified by obtaining ciprofloxacin hydrochloride films through low energy electron beam deposition and layering growth of CIP and Mg-HA films.
APPLIED SURFACE SCIENCE
(2021)
Article
Materials Science, Ceramics
Jialin Yang, Aiying Chen, Fang Liu, Lijian Gu, Xiaofeng Xie, Zhiying Ding
Summary: The thermal stability, hydrophobicity, and corrosion resistance of the PDMS-ZrO2 coatings are substantially improved by introducing ZrO2 nanoparticles. Depending on the ZrO2 content, the PDMS-ZrO2 hybrids exhibit superior corrosion resistance.
CERAMICS INTERNATIONAL
(2022)
Article
Biochemistry & Molecular Biology
Iryna Kozina, Halina Krawiec, Maria Starowicz, Magdalena Kawalec
Summary: Spin coating technique was used to deposit chitosan coatings on the surface of Mg20Zn magnesium alloy, resulting in increased corrosion resistance by forming CaSiO3 and Ca-3(PO4)(2) compounds on its surface. Corrosion rate was reduced from 3.2 mm/year to 1.2 mm/year for uncoated and coated substrates, respectively.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Materials Science, Coatings & Films
Wentao Yu, Huachun Wang, Ruixue Sun, Kezheng Chen
Summary: A novel micro-nano hierarchically structured fluoridated hydroxyapatite (FHAp) coating was successfully synthesized on an AZ31B substrate using a simple one-step electrochemical deposition method in this study. The FHAp coating exhibited higher anti-corrosion properties and better cell biocompatibility compared to pure HAp coating, due to the addition of fluorine ion. This work provides a simple, environment-friendly, and efficient way to prepare FHAp coating on AZ31B alloy with improved corrosion resistance and biocompatibility.
SURFACE ENGINEERING
(2021)
Article
Chemistry, Multidisciplinary
Yan Xu, Yichen Xu, Wentai Zhang, Ming Li, Hans-Peter Wendel, Jurgen Geis-Gerstorfer, Ping Li, Guojiang Wan, Shulan Xu, Tao Hu
Summary: The biodegradability, cytocompatibility, and hemocompatibility of a hot-extruded zinc-copper-iron (Zn-Cu-Fe) alloy were evaluated as a potential biomaterial for craniomaxillofacial implants. The alloy demonstrated predictable in vitro degradation behavior, acceptable cytotoxicity, and appropriate hemocompatibility.
FRONTIERS IN CHEMISTRY
(2022)
Article
Materials Science, Multidisciplinary
Shifeng Wen, Xianglei Liu, Jiahui Ding, Yulai Liu, Ziting Lan, Zimeng Zhang, Guangmeng Chen
Summary: In this study, a hydroxyapatite (HAP) coating was hydrothermally synthesized on the surface of magnesium alloy, resulting in improved morphology structure and corrosion resistance with better control over synthesis conditions. This approach effectively delayed the early corrosion of the magnesium alloy substrate.
PROGRESS IN NATURAL SCIENCE-MATERIALS INTERNATIONAL
(2021)
Article
Chemistry, Applied
Ziqi Liu, Tianxiao Wang, Yingchao Xu, Chen Liang, Guangyu Li, Yunting Guo, Zhihui Zhang, Jianshe Lian, Luquan Ren
Summary: A double-layer dicalcium phosphate dihydrate (DCPD) sandwiched siloxane composite coating was prepared on Mg alloy via chemical conversion, immersion treatment, and biomimetic deposition methods to solve the problem of fast degradation of magnesium alloy. The composite coated sample exhibited a much smaller corrosion current density compared to Mg alloy, and the coating provided continuous protection to the sample. The hydrogen evolution of the optimal coating was significantly lower than that of Mg alloy, and the coated sample demonstrated good biomineralization ability and biocompatibility in cell experiments.
PROGRESS IN ORGANIC COATINGS
(2023)
Review
Chemistry, Physical
Xiaodong Xue, Chunyong Liang, Donghui Wang, Feng Peng
Summary: Magnesium and its alloys have excellent mechanical properties and biodegradability, making them promising candidates in industrial and biomedical fields. However, their rapid corrosion limits their widespread applications. The development of self-healing coatings is essential to repair the damage and enhance their corrosion protection ability.
JOURNAL OF ALLOYS AND COMPOUNDS
(2023)
Article
Materials Science, Multidisciplinary
Anawati Anawati, Medio Febby Fitriana, Muhammad Dikdik Gumelar
Summary: The bilayer anodic film/beeswax-colophony structure effectively improved the corrosion resistance of magnesium alloy surface, showing a significant decrease in corrosion current density and an increase in film resistance.
Article
Chemistry, Multidisciplinary
Meifeng He, Wenbing Lu, Dan Yu, Hao Wang, Shuai Wang, Chenggong Yuan, Aiying Chen
Summary: This study proposes a method of using nacre coatings to control the corrosion rate of Mg-based implants. The results show that samples treated under faint acid conditions exhibit excellent corrosion resistance, while samples treated under slight alkaline conditions demonstrate improved biocompatibility.
FRONTIERS IN CHEMISTRY
(2022)
Article
Materials Science, Multidisciplinary
Pengfei Ji, Shuguang Liu, Hongyun Deng, Hongzhi Ren, Jingkang Zhang, Taojian Sun, Kuixue Xu, Chunbao Shi
Summary: Coatings prepared by magnetron sputtering on titanium alloy substrates can improve the surface hardness and corrosion resistance of the alloy, effectively hinder the growth of columnar structures, and exhibit excellent cytocompatibility.
Article
Materials Science, Coatings & Films
Li-Ping Wu
Summary: The functional hazenite coating deposited on AZ31 Mg alloy showed improved roughness and hydrophilicity, enhanced biocompatibility, reduced degradation rate, and decreased susceptibility to stress corrosion cracking.
SURFACE & COATINGS TECHNOLOGY
(2024)
Article
Nanoscience & Nanotechnology
Chun-Yan Zhang, Hao-Lan Fang, Xin-Peng Liu, Fan-Cheng Meng, Zhong-Qing Tian, Hui-Nan Liu
Summary: The hydrothermal growth mechanism of hydroxyapatite (HA) coating on fluorinated magnesium alloy was explored, with changes in morphology, composition, and crystal phase studied during the process. The results showed that the HA coating underwent structural changes over time, with the formation of a predominantly HA coating. While the HA crystals dissolved slowly and no peeling occurred, pitting corrosion remained the main corrosion mode for the magnesium alloy substrate.
SCIENCE OF ADVANCED MATERIALS
(2021)
Article
Oncology
Lili Chen, Ling Xi, Jie Jiang, Rutie Yin, Pengpeng Qu, Xiuqin Li, Xiaoyun Wan, Yaxia Chen, Dongxiao Hu, Yuyan Mao, Zimin Pan, Xiaodong Cheng, Xinyu Wang, Qingli Li, Danhui Weng, Xi Zhang, Hong Zhang, Quanhong Ping, Xiaomei Liu, Xing Xie, Beihua Kong, Ding Ma, Weiguo Lu
Summary: This study evaluated the efficacy and safety of single-course initial regimens in low-risk gestational trophoblastic neoplasia patients. The results showed that single-course MTX may be a new treatment option, demonstrating similar effectiveness to multi-course MTX and could be considered for low-risk GTN patients.
FRONTIERS OF MEDICINE
(2022)
Article
Nanoscience & Nanotechnology
Po-Hsun Chen, Chih-Yang Lin, Ting-Chang Chang, Jason K. Eshraghian, Yu-Ting Chao, Wei D. Lu, Simon M. Sze
Summary: Resistive random-access memory (RRAM) crossbar arrays have shown great potential for neuromorphic computing, in-memory computing, and high-density storage-class memory applications, but leakage currents through parasitic sneak paths remain a major obstacle. The use of inherent selectors native to switching, such as niobium oxide (NbOx), can help reduce sneak path currents without sacrificing structural simplicity. Experimental results demonstrate abnormal phenomena in the reset process, and the switching behaviors of NbOx devices make them attractive candidates for future memory and in-memory computing applications.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Engineering, Biomedical
Yang Hu, Kuan Jiang, Dongli Wang, Shengyu Yao, Linwei Lu, Huan Wang, Jie Song, Jianfen Zhou, Xingyan Fan, Yong Wang, Weiyue Lu, Jian Wang, Gang Wei
Summary: In this study, a lipoplex was designed to address the unmet demands on intranasal siRNA delivery to the brain for treatment of glioma. The lipoplex exhibited a stable core-shell structure and could be selectively internalized along with cell debris by glioma cells via active macropinocytosis. This lipoplex improved the gene delivery efficiency of intranasal administration and was promising in the perspective of selectively silencing disease-related genes in intracranial tumor.
ACTA BIOMATERIALIA
(2022)
Article
Engineering, Electrical & Electronic
Yuting Wu, Xinxin Wang, Wei D. Lu
Summary: Memristive devices have rich dynamics due to internal state variables determining conductance, which may serve as building blocks for biofaithful neuromorphic systems; these devices can be utilized in compute-in-memory architectures to process temporal data efficiently, implementing synaptic and neuronal functions effectively.
SEMICONDUCTOR SCIENCE AND TECHNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Xuan Zhao, Ruowei Yi, Lei Zheng, Ya Liu, Zhiyun Li, Leiying Zeng, Yanbin Shen, Wei Lu, Liwei Chen
Summary: Prelithiation using lithium-carbon microspheres passivated with a monolayer of octadecylphosphonic acid is demonstrated as an effective strategy to improve the Coulombic efficiency and cycle life of lithium-ion batteries. By supplementing lithium source into the battery, excessive delithiation and destructive phase transformation can be avoided, resulting in higher initial discharge capacity and increased capacity retention after cycles. This work provides a practical approach for developing high energy density and long cycle life LIBs.
Article
Spectroscopy
Fengye Chen, Chen Sun, Zengqi Yue, Yuqing Zhang, Weijie Xu, Sahar Shabbir, Long Zou, Weiguo Lu, Wei Wang, Zhenwei Xie, Lanyun Zhou, Yan Lu, Jin Yu
Summary: Raman spectroscopy shows promise for detecting ovarian cancer, but faces challenges in distinguishing between cancer, cyst, and normal samples. The study found distinct behaviors in the Raman spectra of the three types of samples, which were further visualized in a high dimensional space.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Engineering, Environmental
Peipei Su, Haitao Zhang, Lipeng Yang, Chunxian Xing, Shanshan Pan, Wei Lu, Suojiang Zhang
Summary: This study systematically investigates the effects of conductive additives on the rheological and electrochemical properties of suspension electrodes. The results show that different additives have different percolation thresholds and inflection points. The 1.5 wt.% KB-based suspension exhibits superior cycle and rate performances.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Instruments & Instrumentation
Qing Li, Ting He, Kun Zhang, Yunlong Xiao, Ke Deng, Jinshui Miao, Ning Li, Wenjuan Wang, Wei Lu
Summary: In this study, InGaAs/InP avalanche photodetectors with various guard ring structures were investigated. It was found that deeper guard rings are more effective in preventing edge breakdown and reducing surface electric field. The results also showed that guard rings can inhibit edge breakdown.
INFRARED PHYSICS & TECHNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Sunyi Wu, Linwei Lu, Jianfen Zhou, Danni Ran, Songli Wang, Qianzhu Xu, Weixia Xu, Jun Wang, Yu Liu, Cao Xie, Zimiao Luo, Weiyue Lu
Summary: In this study, we developed a modified cabazitaxel nanocrystal-loaded liposome targeted to all stages of glioma and demonstrated its therapeutic efficacy in vitro and in a mouse model. The carrier exhibited excellent targeting and barrier-crossing capabilities, effectively killing glioma cells.
JOURNAL OF CONTROLLED RELEASE
(2022)
Article
Computer Science, Information Systems
Tingting Chen, Xuechen Liu, Ruiwei Feng, Wenzhe Wang, Chunnv Yuan, Weiguo Lu, Haizhen He, Honghao Gao, Haochao Ying, Danny Z. Chen, Jian Wu
Summary: In this study, a new cervical lesion detection method for colposcopic images is proposed, which tackles the challenges posed by the specific characteristics of these images. The method utilizes novel feature enhancing mechanisms and achieves more accurate localization and diagnosis. Experimental results demonstrate the superiority of the proposed method over state-of-the-art models on four widely used metrics.
IEEE JOURNAL OF BIOMEDICAL AND HEALTH INFORMATICS
(2022)
Article
Optics
Ruixuan Yi, Xutao Zhang, Chen Li, Bijun Zhao, Jing Wang, Zhiwen Li, Xuetao Gan, Li Li, Ziyuan Li, Fanlu Zhang, Liang Fang, Naiyin Wang, Pingping Chen, Wei Lu, Lan Fu, Jianlin Zhao, Hark Hoe Tan, Chennupati Jagadish
Summary: This study demonstrates that III-V semiconductor nanowire (NW) lasers can be used for self-frequency conversion to extend their working wavelengths. Extra visible laser output can be obtained from a GaAs/In(0.16)Ga(0.84)As core/shell NW through the process of second-harmonic generation. In addition, multiple self-frequency-conversion lasing modes are observed in a larger diameter NW laser due to second-harmonic generation and sum-frequency generation.
LIGHT-SCIENCE & APPLICATIONS
(2022)
Article
Nanoscience & Nanotechnology
Huigang Shi, Nan Zong, Shaopeng Li, Jianwen Le, Guangfa Huang, Jiuxiao Li, Jianwei Mao, Weijie Lu
Summary: We observed an interesting phenomenon in a new polycrystalline zirconium alloy where the intensity and attenuation of yield drop behavior increase and decrease, respectively, with increasing strain. This yield discontinuity is attributed to the recombination of climb-dissociated partials introduced by previous strain, and the work hardening or softening stage with increasing or decreasing partial dislocations results in the progressive intensification or attenuation of yield drop, respectively. The anisotropic response of the strain hardening-softening transition leads to relatively higher values of yield drop and increment-decrement transition strain along the rolling direction (-5.5 MPa and -21%, respectively) compared to the transverse direction (-4.6 MPa and -10%, respectively).
MATERIALS SCIENCE AND ENGINEERING A-STRUCTURAL MATERIALS PROPERTIES MICROSTRUCTURE AND PROCESSING
(2022)
Article
Biochemistry & Molecular Biology
Mengting Wu, Qiongzi Qiu, Qing Zhou, Jia Li, Juze Yang, Chengcai Zheng, Aoran Luo, Xufan Li, Honghe Zhang, Xiaodong Cheng, Weiguo Lu, Pengyuan Liu, Bingjian Lu, Yan Lu
Summary: This study identifies circFBXO7, a novel circRNA, as a tumor suppressor in ovarian cancer. The circFBXO7/miR-96-5p/MTSS1 axis is found to be an important regulator in the Wnt/beta-catenin signaling pathway.
Article
Engineering, Mechanical
Weiping Lu, Wen Cui, Xiaogang Zhang, Yali Zhang, Shu Yang, Jian Pu, Junyan Li, Zhongmin Jin
Summary: The friction and wear behaviors between cartilage replacement materials and articular cartilage are crucial for the function and performance of the replacements. This study investigated the difference between cross-shear motion and reciprocal linear motion on the frictional and wear behaviors of cartilage, as well as the effect of bearing surface roughness. The results showed that there was no significant difference between the two motion types. The water contact angle of the bearing surface affected the friction and wear behaviors for low roughness implants, while the surface roughness of the material affected the behaviors for high roughness implants. PEEK was found to be a suitable material for osteochondral implants.
PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART J-JOURNAL OF ENGINEERING TRIBOLOGY
(2023)
Article
Cell Biology
Chen Yang, Yiwen Zang, Siqi Wu, Quan Zhou, Yuxi Ou, Qiang Ding, Hao Wang, Zuquan Xiong
Summary: This study demonstrates that the circFTO/miR-514b-3p/DUSP4 axis plays an important role in the development of ccRCC and may serve as a potential biomarker and therapeutic target.
CELL DEATH DISCOVERY
(2022)