Lentiviral-Mediated Short Hairpin RNA Knockdown of MTDHInhibits Cell Growth and Induces Apoptosis by Regulatingthe PTEN/AKT Pathway in Hepatocellular Carcinoma

Thymosin alpha 1 suppresses proliferation and induces apoptosis in breast cancer cells through PTEN-mediated inhibition of PI3K/Akt/mTOR signaling pathway

(2015) Yan Guo et al.   APOPTOSIS

Loss of PTEN expression is associated with aggressive behavior and poor prognosis in Middle Eastern triple-negative breast cancer

(2015) Shaham Beg et al.   BREAST CANCER RESEARCH AND TREATMENT

PTEN loss is associated with follicular variant of Middle Eastern papillary thyroid carcinoma

(2015) S Beg et al.   BRITISH JOURNAL OF CANCER

Effects of Sorafenib Dose on Acquired Reversible Resistance and Toxicity in Hepatocellular Carcinoma

(2015) E. A. Kuczynski et al.   CANCER RESEARCH

FOXO1/3 and PTEN Depletion in Granulosa Cells Promotes Ovarian Granulosa Cell Tumor Development

(2015) Zhilin Liu et al.   MOLECULAR ENDOCRINOLOGY

p53 in survival, death and metabolic health: a lifeguard with a licence to kill

(2015) Flore Kruiswijk et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Kras activation in p53-deficient myoblasts results in high-grade sarcoma formation with impaired myogenic differentiation

(2015) Timothy McKinnon et al.   Oncotarget

Pten Regulates Epithelial Cytodifferentiation during Prostate Development

(2015) Isabel B. Lokody et al.   PLoS One

Genetic Deletion of AEG-1 Prevents Hepatocarcinogenesis

(2014) C. L. Robertson et al.   CANCER RESEARCH

Metadherin Is a Prognostic Predictor of Hepatocellular Carcinoma after Curative Hepatectomy

(2013) Soomin Ahn et al.   Gut and Liver

AEG-1 expression characteristics in human non-small cell lung cancer and its relationship with apoptosis

(2013) Zun-fu Ke et al.   MEDICAL ONCOLOGY

LXRα-mediated downregulation of FOXM1 suppresses the proliferation of hepatocellular carcinoma cells

(2013) C Hu et al.   ONCOGENE

Akt-p53-miR-365-cyclin D1/cdc25A axis contributes to gastric tumorigenesis induced by PTEN deficiency

(2013) Shui-Long Guo et al.   Nature Communications

Astrocyte elevated gene-1 promotes hepatocarcinogenesis: Novel insights from a mouse model

(2012) Jyoti Srivastava et al.   HEPATOLOGY

Hepatocellular carcinoma

(2012) Alejandro Forner et al.   LANCET

Metadherin Promotes Hepatocellular Carcinoma Metastasis through Induction of Epithelial-Mesenchymal Transition

(2011) K. Zhu et al.   CLINICAL CANCER RESEARCH

Management of hepatocellular carcinoma: An update

(2011) Jordi Bruix et al.   HEPATOLOGY

RIP1 Activates PI3K-Akt via a Dual Mechanism Involving NF- B-Mediated Inhibition of the mTOR-S6K-IRS1 Negative Feedback Loop and Down-regulation of PTEN

(2009) S. Park et al.   CANCER RESEARCH

The Multifaceted Role of MTDH/AEG-1 in Cancer Progression

(2009) G. Hu et al.   CLINICAL CANCER RESEARCH

17βE2 promotes cell proliferation in endometriosis by decreasing PTEN via NFκB-dependent pathway

(2009) Hui Zhang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Astrocyte elevated gene-1 is a proliferation promoter in breast cancer via suppressing transcriptional factor FOXO1

(2009) J Li et al.   ONCOGENE

Astrocyte elevated gene-1 (AEG-1) functions as an oncogene and regulates angiogenesis

(2009) Luni Emdad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial

(2008) Ann-Lii Cheng et al.   LANCET ONCOLOGY