Article
Biochemical Research Methods
Yuling Liang, Huihui Yang, Wen Yin, Yanfei Zhang, Yuzhi Xu, Si-Yang Liu, Zong Dai, Xiaoyong Zou
Summary: In this study, we report the use of polydopamine-modified gold nanoparticles as nanocarriers for long-term monitoring of miRNA in living cells. This method achieves high sensitivity and selectivity and effectively protects the probes from hydrolysis in the intracellular environment.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Physical
Eric H. Hill, Claire Goldmann, Cyrille Hamon, Marcel Herber
Summary: This study demonstrates a simple and fast method for laser-controlled printing of plasmonic nanoparticles onto nonplasmonic substrates, and observes the phenomena of melting and the characteristics of assemblies. This work provides a foundation for future research on controlling the hierarchical structure of nanoparticle assemblies formed at the bubble interface for applications in sensing and devices.
JOURNAL OF PHYSICAL CHEMISTRY C
(2022)
Article
Chemistry, Analytical
Li Zou, Xinghui Li, Yufen Lai
Summary: An enzyme-free colorimetric aptasensor was developed for the sensitive detection of kanamycin in complex samples, exhibiting high sensitivity and selectivity with a broad linear range and a limit of detection of 10 pM. The aptasensor integrates target-triggered catalytic hairpin assembly (CHA) amplification with the aggregation of DNA-gold nanoparticle probes, leading to a colorimetric readout that can be visualized by naked eye or measured by UV-vis spectroscopy. The aptasensor also demonstrates excellent applicability for kanamycin detection in complex samples with satisfactory recoveries and results comparable to those of the ELISA method, suggesting great potential applications in various fields.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Physical
Xin Wang, Zhansen Yang, Yunyi Li, Kunlun Huang, Nan Cheng
Summary: This study explores the interfacial interaction between DNA and AuNP surface, and proposes various universal routes for promoting freeze anchoring. Non-thiolated DNA anchoring, which offers significant advantages, is emphasized. The importance of sequence structure and preparation process optimization is highlighted, which can significantly advance the applications of DNA-functionalized AuNP-based biosensors.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2024)
Article
Chemistry, Analytical
Jianmei Wang, Hong Zhou, Jing Liu, Wenrong Yang
Summary: By controlling surface nanoarchitectures of DNA modified electrode, a new biosensing interface for the detection of p53 gene was designed, showing high performance with potential applications in clinical diagnosis and biomedical research.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Kithmie Malagoda Pathiranage, Elvan Cavac, Tien-Hao Chen, Bijoyita Roy, Craig T. Martin
Summary: T7 RNA polymerase is commonly used for RNA synthesis, but it has a problem of producing longer than encoded RNA products. In this study, a simple and novel modification in the DNA is introduced to strengthen promoter binding, which dramatically reduces self-primed extension, increases RNA yield, and reduces the need for extensive purifications.
NUCLEIC ACIDS RESEARCH
(2023)
Article
Engineering, Biomedical
Xiaoyi Ma, Wuping Zhou, Haiwen Li, Bo Zhang, Peng Miao
Summary: In this study, the protection of hetero-nanostructure of MnO2 and AuNPs from salt-induced aggregation was systematically investigated using DNA as a medium. By analyzing the optical responses of these nanostructures, highly sensitive analysis of miRNA can be achieved. The excellent analytical performances are attributed to the unique features of MnO2@Au nanostructures and signal amplification designs, making them promising for the construction of novel biosensors in clinical applications.
MATERIALS TODAY BIO
(2023)
Article
Chemistry, Multidisciplinary
Ahmad Junaid, Chew Hee Ng, Ing Hong Ooi
Summary: This study synthesized and characterized a nanogold-{[(Cu)(phen)(cys)(H2O)]NO3}n conjugate, and evaluated its antiproliferative property against breast cancer cells. The results showed that the nanogold-copper complex conjugate demonstrated selective anticancer activity, highlighting its potential as an anticancer agent.
Article
Chemistry, Multidisciplinary
Anurag Chaudhury, Koushik Debnath, Nikhil R. Jana, Jaydeep K. Basu
Summary: The study investigates the interaction between nanoparticles and cell membranes, and identifies key parameters, including charge, crowding, and membrane fluidity, that determine the adsorbed concentration and unbinding transition of nanoparticles.
Article
Optics
Mingjie Wang, Chunying Guan, Lin Cheng, Jing Liu, Jing Yang, Jinhui Shi, Zhihai Liu, Jun Yang, Libo Yuan
Summary: The study introduces and demonstrates multicore fiber beam shaping devices based on surface plasmon polaritons (SPPs) for trapping nanospheres, showing high integration and flexibility, suitable for long-distance and multi-particle trapping applications.
Article
Chemistry, Multidisciplinary
Liran Tian, Xiangwei Song, Tianjiao Liu, Anfeng Li, Yang Ning, Xiuyi Hua, Deming Dong, Dapeng Liang
Summary: A UV-Visible and fluorescence detection method was designed for the determination of acetamiprid based on the specific identification ability of aptamers. The presence of acetamiprid could be clearly determined through the aggregation of gold nanoparticles and the redshifting of the UV-vis absorption peak. This combined method showed a wide detection range and a low detection limit, making it a potential simple method for the determination of acetamiprid residues in natural water bodies.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Maurice Retout, Bryan Gosselin, Amina Adrovic, Pascale Blond, Ivan Jabin, Gilles Bruylants
Summary: In this study, a thin and robust coating based on calixarene-diazonium salts was developed to maintain the anisotropic structure of silver nanoplates, resulting in increased lifetime and stability. This coated silver nanoplates were then used for the detection of rabbit immunoglobulin G and Anti-SARS-CoV-2 IgG, achieving a low limit of detection and successful detection in human plasma. Additionally, the wide range of colors provided by the silver nanoplates allowed for the design of a multicolor multiplex assay for simultaneous detection of multiple analytes.
Article
Chemistry, Analytical
Qiang Liu, Mei Liu, Yan Jin, Baoxin Li
Summary: In this study, an enzyme-free signal amplification method for miRNA detection was developed using target-triggered catalytic hairpin assembly (CHA). The method showed high sensitivity and fast detection speed, with good recoveries in serum samples.
Review
Chemistry, Multidisciplinary
Jessica Sui Ying Ooi, Siu Yee New
Summary: Gold nanoparticles have been widely used in biosensing due to their remarkable physicochemical properties. Integrating them with enzyme-free target amplification methods such as HCR and CHA provides a new paradigm in biosensing, improving the assay performance.
Article
Chemistry, Multidisciplinary
Lixian Huang, Jinling Zhang, Lifang Pang, Shengqiang Hu, Liangliang Zhang, Shulin Zhao
Summary: By controlling the melting temperature-dependent assembly-disassembly of pSNAs, a temperature-self-controllable and biomarker-activatable photothermal effect in vivo was achieved.
CHEMICAL COMMUNICATIONS
(2021)