期刊
ANALYTICAL CHEMISTRY
卷 84, 期 9, 页码 4029-4035出版社
AMER CHEMICAL SOC
DOI: 10.1021/ac203381n
关键词
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资金
- Ian Potter Foundation
- Discovery Early Career Researcher Award (DECRA) [DE120101402]
- Australian Research Council
We demonstrate an active microfluidic platform that integrates dielectrophoresis for the control of silver nanoparticles spacing, as they flow in a liquid channel. By careful control of the nanoparticles spacing, we can effectively increase the surface-enhanced Raman scattering (SERS) signal intensity based on augmenting the number of SERS-active hot-spots, while avoiding irreversible aggregation of the particles. The system is benchmarked using dipicolinate (2,6-pyridinedicarboxylic acid) (DPA), which is a biomarker of Bacillus anthracis. The validity of the results is discussed using several complementing characterization scenarios.
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