Article
Food Science & Technology
Sher Ali, Vanessa Theodoro Rezende, Sana Ullah, Esther Lima de Paiva, Fernando Gustavo Tonin, Carlos Humberto Abdullah, Carlos Humberto Corassin, Carlos Augusto Fernandes de Oliveira
Summary: This review introduces the use of foodomics by mass spectrometry and nuclear magnetic resonance spectroscopy for food processing and quality safety concerns. By monitoring the changes in food molecular components during processing, production, storage, and packaging, the food industry can improve processing, preservation, and safety measures.
Review
Cell Biology
Vishnu Vardhan Byroju, Aisha Shigna Nadukkandy, Marco Cordani, Lekha Dinesh Kumar
Summary: Retinoblastoma is a rare intraocular tumor that affects children and can become life-threatening if not treated early. The survival rate in developed countries is over 95% due to advancements in diagnosis and treatment techniques. Early diagnosis and genetic research are crucial for improving survival rates.
CELL COMMUNICATION AND SIGNALING
(2023)
Article
Food Science & Technology
Aamir Iqbal, Patrick Schulz, Syed S. H. Rizvi
Summary: The pomace produced by the agro-fruit industry contains valuable bioactive compounds that can improve human health through anti-inflammation, antioxidant, anti-allergenic, anti-carcinogenic and other activities. This review discusses the composition and green extraction technologies of fruit pomace from commonly consumed fruits, as well as the comprehensive utilization of pomace for sustainable development in the agro-fruit industry. Studies are also exploring methods to improve the economic attractiveness and functionality of fruit pomace for various applications.
Article
Food Science & Technology
Steven D. Prager, Keith Wiebe
Summary: This paper provides an overview of a series of research articles on agricultural futures, discussing key issues such as how past trends can be used to predict future outcomes and different perspectives on investment in agricultural research.
GLOBAL FOOD SECURITY-AGRICULTURE POLICY ECONOMICS AND ENVIRONMENT
(2021)
Article
Biochemistry & Molecular Biology
Justin E. Fichtner, Jennifer Patnaik, Karen L. Christopher, J. Mark Petrash
Summary: The study surveyed cataract surgeons' perspectives on preventative PCO therapy, finding that the majority believe there is a need for such treatment and are interested in incorporating it into surgical protocols. They perceive benefits including optimizing visual outcomes, eliminating complications, and providing solutions for specific patient groups.
CHEMICO-BIOLOGICAL INTERACTIONS
(2021)
Review
Biochemical Research Methods
Ruby C. Y. Lin, Jessica C. Sacher, Pieter-Jan Ceyssens, Jan Zheng, Ali Khalid, Jonathan R. Iredell
Summary: After a century of use in human infection, there is a clear need to improve the reproducibility, safety, and speed of providing suitable phages. Building a national consortium and sustainable phage biobank could serve as a model for phage therapy initiatives.
CURRENT OPINION IN BIOTECHNOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Reza Foudazi, Ryan Zowada, Ica Manas-Zloczower, Donald L. Feke
Summary: In this feature article, the physical properties and production methods of porous hydrogels are critically reviewed. The focus is on nondense hydrogels that have physical pores in addition to the space between adjacent cross-links in the polymer network. The article discusses theories on swelling kinetics, equilibrium swelling, structure-stiffness relationship, and solute diffusion in dense hydrogels, and proposes future directions for developing models for porous hydrogels. Different methods for making hydrogels with physically incorporated pores are also briefly reviewed, including bubble generation approaches and templating approaches.
Review
Cell Biology
Atef Badji, Jessica Youwakim, Alexandra Cooper, Eric Westman, Anna Marseglia
Summary: This narrative review provides an evidence-based summary of the link between individual vascular risk/disorders and cognitive dysfunction, as well as the potential structural and biochemical pathophysiological processes. It highlights the need for future research to focus on comorbid vascular burden, integrate imaging and fluid biomarkers, implement a life-course approach, consider neuroprotective influences of positive life exposures, and address biological sex at birth and gender differences.
AGEING RESEARCH REVIEWS
(2023)
Review
Biochemical Research Methods
Gloria Dominguez-Rodriguez, Lidia Montero, Miguel Herrero, Alejandro Cifuentes, Maria Castro-Puyana
Summary: This study provides an overview of the main applications of capillary electromigration (CE) methods in food analysis and Foodomics. Papers published between March 2021 and March 2023 were reviewed. The study highlights the various CE methods that have been developed and utilized for the analysis of different molecules in food and beverages. Additionally, new CE procedures for chiral separation, evaluating the effects of food processing, and recent developments in microchip CE and Foodomics applications are discussed.
Review
Biochemical Research Methods
Alberto Valdes, Gerardo Alvarez-Rivera, Barbara Socas-Rodriguez, Miguel Herrero, Alejandro Cifuentes
Summary: This paper presents a revision of the main applications of capillary electromigration methods in food analysis and Foodomics, including the analysis of different types of molecules in foods and monitoring of food interactions and food processing. New developments in microchips and applications of capillary electrophoresis in Foodomics are discussed, as well as new procedures to investigate food quality, safety, nutritional value, storage, and bioactivity.
Review
Materials Science, Multidisciplinary
Marcos Silva de Sousa, Andersen Escobar Schlogl, Felipe Ramalho Estanislau, Victor Gomes Lauriano Souza, Jane Selia dos Reis Coimbra, Igor Jose Boggione Santos
Summary: Nanotechnology plays a crucial role in food packaging, extending shelf life, enhancing food safety, and providing information to consumers. However, safety considerations and regulations need to be addressed, as potential risks to human health and the environment exist. Despite challenges, nanotechnology-based packaging offers the potential for advancements in food preservation and substantial benefits for manufacturers and consumers.
Review
Oncology
Alyssa Y. Li, Karolina Gaebe, Katarzyna J. Jerzak, Parneet K. Cheema, Arjun Sahgal, Sunit Das
Summary: Intracranial metastatic disease (IMD) is a common complication of cancer that greatly affects patient survival and quality of life. Advances in understanding the epidemiology and pathogenesis of IMD have led to the development of surveillance and treatment algorithms based on prognostic factors and tumor biomolecular characteristics. In addition to surgical resection and radiation therapy, targeted therapy and immunotherapy have emerged as important treatment modalities for IMD. The improvement in imaging sensitivity and specificity, as well as the development of new serological assays, holds promise for revolutionizing the diagnosis of IMD.
FRONTIERS IN ONCOLOGY
(2022)
Review
Health Care Sciences & Services
Sambit K. K. Mohanty, Anandi Lobo, Sourav K. K. Mishra, Liang Cheng
Summary: Bladder cancer is a highly heterogeneous disease with different histopathologic and molecular characteristics. Recent advances in understanding the molecular pathology of bladder cancer have led to the identification of promising biomarkers and therapeutic targets, which may improve disease classification, prognosis, and the development of noninvasive detection and surveillance strategies. These advancements may soon have a significant impact on precision medicine and clinical management for bladder cancer patients.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Review
Oceanography
Mohammed Shah Nawaz Chowdhury, M. Shahadat Hossain, Sheikh AftabUddin, Mohammed Alamgir, S. M. Sharifuzzaman
Summary: Seaweeds production in Bangladesh has great potential for sustainable aquaculture. Despite existing challenges, the industry can be promoted through suitable site selection, improved techniques, and increasing market demand.
OCEAN & COASTAL MANAGEMENT
(2022)
Article
Materials Science, Multidisciplinary
Reham Fathi, Hongyu Wei, Bassiouny Saleh, N. Radhika, Jinghua Jiang, Aibin Ma, Mahmoud H. Ahmed, Qin Li, Kostya Ken Ostrikov
Summary: This review paper provides a detailed analysis of production techniques, microstructure features, mechanical properties, wear resistance, and corrosion behavior of functionally graded coatings (FGCs). It also explores FGC classifications and applications, as well as future directions for research in this field.
APPLIED MATERIALS TODAY
(2022)
Article
Biochemistry & Molecular Biology
Jose David Sanchez-Martinez, Ana Rita Garcia, Gerardo Alvarez-Rivera, Alberto Valdes, Maria Alexandra Brito, Alejandro Cifuentes
Summary: Agrifood by-products and microalgae are rich sources of bioactive compounds with neuroprotective properties, but their effectiveness is limited by the blood-brain barrier (BBB). In this study, green extracts from various sources were tested for their permeability across an in vitro BBB model. Results showed that neuroprotective compounds like terpenoids, phytosterols, and phenolic compounds had high permeability. These findings support the potential use of these natural extracts as functional ingredients in food supplements or nutraceuticals with neuroprotective claims.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biotechnology & Applied Microbiology
Mari Carmen Ruiz-Dominguez, Jose Antonio Mendiola, Jose David Sanchez-Martinez, Monica Bueno, Pedro Cerezal-Mezquita, Elena Ibanez
Summary: This study reveals the potential of the brown seaweed Durvillaea antarctica, commonly consumed in Chile, as an important food with antioxidant and neuroprotective properties. The bioactivity of the seaweed extracts was evaluated using conventional and pressurized liquid extraction methods. The results showed that pressurized liquid extraction improved the extraction yield and antioxidant activities compared to conventional extraction. Furthermore, the study identified the optimal conditions for obtaining extracts with high yields and neuroprotective effects.
JOURNAL OF APPLIED PHYCOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Davide Liberti, Paola Imbimbo, Enrica Giustino, Luigi D'Elia, Giarita Ferraro, Angela Casillo, Anna Illiano, Gabriella Pinto, Maria Chiara Di Meo, Gerardo Alvarez-Rivera, Maria Michela Corsaro, Angela Amoresano, Armando Zarrelli, Elena Ibanez, Antonello Merlino, Daria Maria Monti
Summary: A biorefinery approach was developed to extract high-value bioproducts, including exopolysaccharides, phycoerythrin, and β-carotene, from the culture of Porphyridium cruentum.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2023)
Article
Biochemistry & Molecular Biology
Juliana A. Barreto Peixoto, Gerardo alvarez-Rivera, Anabela S. G. Costa, Susana Machado, Alejandro Cifuentes, Elena Ibanez, M. Beatriz P. P. Oliveira, Rita C. Alves
Summary: This study investigated the antioxidant potential, phenolic profile, and free amino acid profile of lemon verbena infusions from different commercial brands. Various assays showed that the infusions exhibited high antioxidant activity, which was correlated with total phenolics and total flavonoid contents. Phenylalanine also appeared to have an impact on the antioxidant activity. Significant differences were found among the evaluated parameters for one of the commercial brands, possibly due to different geographical origins. Overall, lemon verbena infusions contain a variety of bioactive compounds with therapeutic potential.
Article
Food Science & Technology
Joao V. B. Borsatto, Edvaldo V. S. Maciel, Alejandro Cifuentes, Fernando M. Lancas
Summary: Sample preparation is a complex and time-consuming procedure that directly affects analysis quality. Recent studies have explored online extraction coupled with liquid chromatography-mass spectrometry (OLE-LC-MS) as a promising alternative for analyzing analytes in complex solid matrices. In this study, the lecithin profile in various seeds was analyzed using OLE-LC-MS, demonstrating its feasibility without the need for offline solvent extraction. Optimization of the extraction phase gradient method and exploration of different analytical columns improved separation and repeatability. Overall, the OLE-LC-MS approach showed potential for lipidomics analysis in the future.
Editorial Material
Nutrition & Dietetics
Elena Ibanez, Alejandro Cifuentes
FRONTIERS IN NUTRITION
(2023)
Review
Chemistry, Analytical
Brenda Lee Simas Porto, Alberto Valdes, Alejandro Cifuentes, Gerardo Alvarez-Rivera
Summary: This article revisits recent articles that have used capillary electromigration techniques to study various phytochemicals between 2018 and 2021. The manuscript is divided based on the different separation methods used, and the main aspects of each application are briefly discussed, including sample preparation, advantages and disadvantages of the developed methods, problems encountered during the process, and ways to solve them.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Article
Biochemical Research Methods
Miguel Herrero
Summary: The increasing interest in natural bioactive compounds has led to the development of new extraction processes that focus on environmental friendliness and utilize new technologies and solvents to maximize the valorization of natural sources.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Review
Biochemical Research Methods
Gloria Dominguez-Rodriguez, Lidia Montero, Miguel Herrero, Alejandro Cifuentes, Maria Castro-Puyana
Summary: This study provides an overview of the main applications of capillary electromigration (CE) methods in food analysis and Foodomics. Papers published between March 2021 and March 2023 were reviewed. The study highlights the various CE methods that have been developed and utilized for the analysis of different molecules in food and beverages. Additionally, new CE procedures for chiral separation, evaluating the effects of food processing, and recent developments in microchip CE and Foodomics applications are discussed.
Article
Biochemical Research Methods
Laura Oliveira Lago, Pawel Swit, Mairon Moura da Silva, Aline Telles Biasoto Marques, Juliane Welke, Lidia Montero, Miguel Herrero
Summary: In this study, a new method based on comprehensive two-dimensional liquid chromatography coupled to a diode array detector and tandem mass spectrometry was developed to obtain the phenolic profile of Malbec grapes cultivated in Brazil. The method was also used to investigate the changes in phenolic composition during a 10-week ripening period. Results showed an increase in anthocyanin content in grapes during the first 5-6 weeks of ripening, followed by a decrease towards week 9. The two-dimensional approach proved to be a useful tool for characterizing the complex phenolic profile of these samples.
JOURNAL OF CHROMATOGRAPHY A
(2023)
Article
Food Science & Technology
Pouya Mohammadnezhad, Alberto Valdes, Ruth E. Barrientos, Elena Ibanez, Jane Mara Block, Alejandro Cifuentes
Summary: In this study, the lipidic fraction of Amazonian Pentaclethra macroloba nuts was chemically characterized using supercritical fluid extraction. The results suggest that the by-products of pracaxi oil extraction are a valuable source of bioactive compounds with neuroprotective potential.
Article
Pharmacology & Pharmacy
Maria Taboada-Alquerque, Danilo Pajaro-Valenzuela, Karina Caballero-Gallardo, Alejandro Cifuentes, Elena Ibanez, Maicol Ahumedo-Monterrosa, Elena E. Stashenko, Jesus Olivero-Verbel
Summary: A natural compound called carnosol found in rosemary has been identified as a potential anti-tumor and anti-inflammatory agent. Through network pharmacology, plausible human targets for carnosol were identified, and it was found to be closely related to infection and inflammation. These findings suggest that carnosol may exert its effects through inducing an immuno-inflammatory response.
SCIENTIA PHARMACEUTICA
(2023)
Review
Chemistry, Analytical
Gerson-Dirceu Lopez, Gerardo Alvarez-Rivera, Chiara Carazzone, Elena Ibanez, Chad Leidy, Alejandro Cifuentes
Summary: Natural carotenoids have important applications in pharmaceutical, cosmetic, nutraceutical, and food industries. The use of bacteria for carotenoid production has gained much attention in recent years. This review summarizes the methods for extracting and identifying bacterial carotenoids and highlights the use of high-performance liquid chromatography-mass spectrometry (HPLC-MS) for analysis and identification. The potential commercial use of these carotenoids is also discussed.
CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
(2023)
