Article
Materials Science, Multidisciplinary
Mingming Shen, Jiahao Ni, Yanxia Cao, Yanyu Yang, Wanjie Wang, Jianfeng Wang
Summary: This study demonstrates the remarkable performance of Ti3C2Tx MXene with low infrared emissivity in electric/solar heating, achieving high-temperature heating with low driving voltage and practical solar irradiation. The material also exhibits excellent passive radiative heating capability, enabling zero-energy heating.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2023)
Article
Chemistry, Physical
Xingyuan Du, Xiangxin Li, Yuxuan Zhang, Xinyi Guo, Zhengji Li, Yanxia Cao, Yanyu Yang, Wanjie Wang, Jianfeng Wang
Summary: Visible transparent, low-emissivity polymeric films were successfully fabricated by nanocoating decoration of indium tin oxide (ITO) and MXene on polyethylene terephthalate (PET) film surface. The resulting films exhibited high visible transmittance, low emissivity, high solar absorptivity, and electrical conductivity, enabling excellent solar to thermal conversion performance. These films also demonstrated superior infrared stealth and thermal management capabilities, making them highly promising for applications in areas such as building daylighting and personal precision heating.
Article
Chemistry, Physical
Xingyuan Du, Xiangxin Li, Yuxuan Zhang, Xinyi Guo, Zhengji Li, Yanxia Cao, Yanyu Yang, Wanjie Wang, Jianfeng Wang
Summary: Transparent and low-infrared-emissivity polymeric films with excellent properties have been successfully fabricated, showing potential applications in areas such as infrared stealth, building daylighting, and thermal management.
Article
Chemistry, Analytical
Yu Du, Xiaoyue Zhang, Yue Jia, Rui Feng, Tingting Wu, Nuo Zhang, Huangxian Ju
Summary: The researchers proposed a host-guest recognition strategy to enhance the electrochemiluminescence (ECL) efficiency and stability of gold nanoclusters (AuNCs). The prepared AuNCs showed improved ECL emission efficiency and stability, and exhibited excellent sensing results for D-dimer.
ANALYTICAL CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Chao Wang, Songqin Liu, Huangxian Ju
Summary: This article reviews the origin and development of electrochemiluminescent nanoemitters and their application in sensitive detection of protein biomarkers. It specifically focuses on metal-organic frameworks (MOFs)-based nanoemitters and discusses effective strategies to enhance the electrochemiluminescent response and improve immunosensing sensitivity. The article comprehensively presents the application of electrochemiluminescent nanoemitters in the diagnosis of cancers and other diseases, particularly lung cancer and heart diseases. The recent advancement of electrochemiluminescent imaging with nanoemitters for the detection of multiplex protein biomarkers on single cell membranes is also highlighted. Finally, the future opportunities and challenges in the field of electrochemiluminescent biosensing are discussed.
BIOELECTROCHEMISTRY
(2023)
Article
Chemistry, Analytical
Junjie Hu, Fei Liu, Yunlong Chen, Jia Fu, Huangxian Ju
Summary: This work proposed a signal-on mass spectrometric biosensing strategy with a phospholipid-structured mass-encoded microplate for assessment of multiplex MMP activities, which is of great importance for cancer diagnosis and staging.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Ze-Rui Zhou, Da-Wei Li, Ruo-Can Qian, Huangxian Ju
Summary: We developed a DNAzyme-powered DNA walker to visualize the cooperative expression of mutant p53 and telomerase in living cells. The DNA walker allows for real-time monitoring of mutant p53 and active telomerase expression in cancer cells, providing new insights into the study of cancer pathway-relevant biomarkers.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Lele Li, Siqi Yu, Jie Wu, Huangxian Ju
Summary: We developed a sensitive electrochemiluminescence (ECL) biosensing strategy for the detection of activated CRISPR/Cas12a using polymer dots (Pdots) as emitters. The strategy involves the regulation of binding between Pdots-DNA and a biosensor, and the enhancement of ECL emission through the local surface plasmon resonance (LSPR) effect of electrochemically deposited Au nanoparticles (depAuNPs). The integration of target DNA-triggered catalysis and the LSPR effect greatly improves the sensitivity of ECL analysis.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Weisu Kong, Da Zhu, Yong Zhang, Rengan Luo, Jing Ma, Jianping Lei, Huangxian Ju
Summary: To improve the photoelectrochemical performance, an additional electron donor/acceptor is typically needed to suppress electron-hole recombination. However, the enhancement is limited due to long-distance diffusion. In this study, a self-supplying electron strategy is designed by coordinating an electron donor 1.4-diazabicyclo[2.2.2]octane (Dabco) in a metal-organic framework (MOF) to enhance PEC performance. The presence of Dabco effectively inhibits electron-hole recombination and leads to a 23.2-fold enhancement in photocurrent. This work provides a new approach for improving the PEC performance of nanomaterials.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Multidisciplinary
Shiyi Bi, Wei Chen, Yanyun Fang, Yingfei Wang, Qing Zhang, Hongqian Guo, Huangxian Ju, Ying Liu
Summary: Clustering of cell membrane receptors can regulate cell behaviors. This study presents a Raji cell Selective MAnipulation of Receptor Clustering (SMARC) strategy for CD20, which is driven by endogenous secretion of Raji cells. The strategy utilizes retractable DNA nanostrings anchored to the cell membrane CD20, which contract in response to Raji cell-secreted VEGF with corresponding CD20 clustering. The SMARC strategy selectively induces apoptosis in Raji cells with minimal interference to normal B cells, and shows promising in vivo therapeutic efficacy.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Review
Chemistry, Multidisciplinary
Rengan Luo, Da Zhu, Huangxian Ju, Jianping Lei
Summary: Electrochemiluminescence (ECL) is a powerful technique that relies on charge transfer between electrochemical intermediates and co-reactants/emitters to form excited emitters. The development of molecular nanocrystals, such as metal-organic frameworks (MOFs) and covalent organic frameworks (COFs), has allowed for the exploration of ECL mechanisms and enhancement strategies. Reticular crystalline nanoemitters with different topologies provide a platform for understanding ECL fundamentals and designing next-generation ECL devices.
ACCOUNTS OF CHEMICAL RESEARCH
(2023)
Article
Chemistry, Analytical
Xue Wang, Dongquan Leng, Faying Li, Lei Liu, Xiang Ren, Jin Yong Lee, Huangxian Ju, Qin Wei
Summary: An efficient photoelectrochemical (PEC) split-type sensor based on a controlled release strategy was successfully established for ultrasensitive and accurate physiological monitoring, with improved visible light absorption efficiency and stability. The sensor separated the immune reaction from the photoelectrochemical conversion process, eliminating interference. The use of Cu2O nanocubes as labels and acid etching improved the sensitivity of the sensor. Under optimized conditions, the PEC sensor showed a wide concentration linear range and a low detection limit for CYFRA21-1 target detection.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Multidisciplinary
Shiya Zhao, Yuanjiao Yang, Yuru Wang, Huipu Liu, Huangxian Ju, Yunlong Chen
Summary: This study presents a functional dendrimer probe that can conveniently detect newly generated sialic acid groups in vivo using a dual-color imaging strategy. It enables the in situ semiquantitative evaluation of sialylation differences between tumor and normal tissues, allowing the investigation of sialylation-related biological events and facilitating clinical tumor diagnosis.
CHEMICAL COMMUNICATIONS
(2023)
Article
Chemistry, Multidisciplinary
Jun Sun, Jie Wu, Huangxian Ju
Summary: The motion ability of enzyme-powered micro/nanomotors is primarily determined by the size of the silica rather than the asymmetric coating of the enzyme. Silica micro/nanomotors at sizes of 500 nm and 2 μm show significant increases in diffusion coefficient, while those larger than 5 μm do not exhibit self-propulsion behavior at all. Although asymmetry enhances the diffusion of the micro/nanomotors, only those at a size of 2 μm are sensitive to the level of asymmetry.
CHEMISTRY-AN ASIAN JOURNAL
(2023)
Article
Chemistry, Analytical
Xue Dong, Xiaoyue Zhang, Xiang Ren, Hongmin Ma, Nuo Zhang, Faying Li, Huangxian Ju, Qin Wei
Summary: In this study, a bandgap-regulated ECL enhancement strategy was developed to improve the ECL efficiency of ZrO2. Through the synthesis of ZrCuO3, which exhibited a narrower bandgap and higher electron transfer efficiency, the ECL efficiency of ZrO2 was enhanced. This strategy provides a novel approach for the sensitive detection of target substances.
ANALYTICAL CHEMISTRY
(2023)
Review
Chemistry, Multidisciplinary
Yuanjiao Yang, Shan Wu, Yunlong Chen, Huangxian Ju
Summary: The detection and mapping of cellular biomarkers is crucial for understanding physiological and pathological processes. SERS technology, with its high sensitivity and multiplex detection capabilities, has emerged as a powerful tool for this purpose.
Article
Chemistry, Multidisciplinary
Farukh Mansoor, Huangxian Ju, Madiha Saeed, Shamsa Kanwal
Summary: This work explores a new precursor for the facile synthesis of gold nanocubes by controlling the morphology of silver nanocubes. The Ag@4MBA@AuNCs nanostructure exhibits a 1010-times enhancement in surface enhanced Raman scattering (SERS) signal, making it a highly sensitive imaging probe for the detection of breast cancer cells. Additionally, this study achieves the catalytic reduction of toxic chemicals through the incorporation of alloy nanoparticles.
Article
Chemistry, Analytical
Jiajun Liu, Yu Du, Aiping Guo, Nuo Zhang, Lei Liu, Dawei Fan, Xue Dong, Qin Wei, Huangxian Ju
Summary: In this study, a sandwich sensing platform was developed using silica-coated silver nanoparticles as a luminescent material and cerium dioxide as a signal quencher for sensitive neuro-specific enolase detection. The core-shell structure protected the silver nanoparticles and improved their luminescence properties. Amino-functionalized cerium dioxide efficiently diminished the luminescence signal, resulting in a highly sensitive and accurate detection mode. This detection strategy showed a powerful capability for biomolecule detection.