期刊
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
卷 16, 期 9, 页码 22636-22661出版社
MDPI
DOI: 10.3390/ijms160922636
关键词
n-3 fatty acids; eicosapentaenoic acids (EPA); docosahexaenoic acid (DHA); lipid peroxidation; cardiovascular diseases; seafood; supplements
资金
- UIT The Arctic University of Norway
omega-3 fatty acids (n-3 FA) have, since the 1970s, been associated with beneficial health effects. They are, however, prone to lipid peroxidation due to their many double bonds. Lipid peroxidation is a process that may lead to increased oxidative stress, a condition associated with adverse health effects. Recently, conflicting evidence regarding the health benefits of intake of n-3 from seafood or n-3 supplements has emerged. The aim of this review was thus to examine recent literature regarding health aspects of n-3 FA intake from fish or n-3 supplements, and to discuss possible reasons for the conflicting findings. There is a broad consensus that fish and seafood are the optimal sources of n-3 FA and consumption of approximately 2-3 servings per week is recommended. The scientific evidence of benefits from n-3 supplementation has diminished over time, probably due to a general increase in seafood consumption and better pharmacological intervention and acute treatment of patients with cardiovascular diseases (CVD).
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