Article
Environmental Sciences
Fan Wang, Fei Liu
Summary: This study investigated the potential effects of Triclosan (TCS) on cellular targets in zebrafish larvae. The results showed that TCS potentially affected reproduction, immune, and metabolism processes in zebrafish larvae.
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
(2023)
Article
Environmental Sciences
Wenzhu Wu, Jing Xu, Yezhi Dou, Jia Yu, Deyang Kong, Lixiang Zhou
Summary: This study aims to understand the bioaccumulation of pyraoxystrobin in fish. The measured bioconcentration factors (BCFs) and clearance rates were compared to estimated values from prediction models, showing close agreement.
Article
Environmental Sciences
Maryam Saemi-Komsari, Reza Pashaei, Sajjad Abbasi, Hamid Reza Esmaeili, Reda Dzingelevic, Behzad Shirkavand Hadavand, Marzieh Pasalari Kalako, Malgorzata Szultka-Mlynska, Renata Gadza, Boguslaw Buszewski, Andrew Turner
Summary: This study found that nanoplastics have an impact on fish in the aquatic environment. The accumulation of nanoplastics was observed in both the digestive and non-digestive organs of the tooth-carp fish, with higher concentrations in the gut, liver, and gill than in the skin and muscle. The presence of triclosan in the diet did not affect the uptake of nanoplastics by the fish, and both contaminants appeared to accumulate independently of each other.
ENVIRONMENTAL POLLUTION
(2023)
Article
Multidisciplinary Sciences
Yusheng Jiao, Brendan Colvert, Yi Man, Matthew J. McHenry, Eva Kanso
Summary: A study reveals that fish prey tend to escape in a direction orthogonal to the predator's heading, which maximizes the distance from fast-moving predators and adapts to the biomechanical constraints of fish escape response.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Pharmacology & Pharmacy
Cheng Peng, Shanqi Zhou, Yinjie Zhang, Hongchang Zhang, Wei Zhang, Siyuan Ling, Shuangqing Hu
Summary: In this study, the accumulation and elimination of nonylphenol (NP) in zebrafish were investigated. The results showed that the LC50 values of NP in zebrafish ranged from 474 to 238 μg/L. The depuration stage followed a first-order kinetic model, with a decreased depuration rate constant (K-2) with higher NP concentration. The half-life (t(1/2)) of NP was shorter in the trunk compared to the whole fish, indicating faster elimination from the trunk by preferential transfer and rapid diffusion in reverse. The bioconcentration factors (BCFSS) suggested that muscle tissue was the major site of NP storage.
Article
Engineering, Environmental
Jing Fu, Zhiyuan Gong, Sungwoo Bae
Summary: The study found that the presence of triclosan and methyl triclosan in water can have different toxic effects on zebrafish embryos, impacting mitochondrial inner membrane function and leading to dysregulation of various GO terms and KEGG pathways.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Environmental Sciences
Qi Lai, Xiaofang Sun, Lianshan Li, Da Li, Minghua Wang, Haiyan Shi
Summary: Dicarboximide fungicides such as procymidone and iprodione exhibit moderate toxicity to adult zebrafish and can be metabolized to the more toxic 3,5-DCA in the fish. Zebrafish showed significant brain damage but lighter damage in gut and gills. In terms of bioaccumulation, procymidone was moderately accumulated while iprodione was lowly accumulated in zebrafish.
Article
Environmental Sciences
Xingxing Yin, Changsheng Guo, Yanghui Deng, Xiaowei Jin, Yanguo Teng, Jian Xu, Fengchang Wu
Summary: The study investigated the uptake, biotransformation, internal distribution, and toxicokinetic processes of zebrafish exposed to methamphetamine and ketamine, finding that the concentrations of these illicit drugs in fish were primarily driven by external concentrations and were not persistent in organs without substantial external contaminant sources.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Biochemistry & Molecular Biology
Lapo Turrini, Michele Sorelli, Giuseppe de Vito, Caterina Credi, Natascia Tiso, Francesco Vanzi, Francesco Saverio Pavone
Summary: In this study, transgenic zebrafish larvae were used to investigate functional alterations during seizure and the involvement of different brain regions. The study found that the epileptic larval brain undergoes transitions between different neural activity states and different brain regions are progressively recruited into seizures of diverse severity.
Article
Biochemistry & Molecular Biology
Qipeng Shi, Huaran Yang, Yangli Chen, Na Zheng, Xiaoyu Li, Xianfeng Wang, Weikai Ding, Bangjun Zhang
Summary: The pesticide trichlorfon used in aquaculture was found to cause developmental neurotoxicity in zebrafish embryos. Trichlorfon exposure led to reduced survival rate, hatching rate, heartbeat, body length, and increased malformation rate in zebrafish larvae. The neurotoxic effects were attributed to the disruption of cholinergic, dopaminergic, and serotonergic signaling, as well as the development of the central nervous system.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Environmental Sciences
Sunil Sharma, Owias Iqbal Dar, Kirpal Singh, Arvinder Kaur, Caterina Faggio
Summary: The study revealed significant effects of Triclosan on biochemical parameters and gene expression in Labeo rohita larvae, with certain biomarkers like glucose, triglycerides, urea, uric acid, and alkaline phosphatase showing significant declines after exposure. Some parameters showed opposite trends during the recovery period, suggesting their importance in identifying the health status of fish under TCS stress.
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
(2021)
Article
Engineering, Environmental
Ling Zhang, Bryan W. Brooks, Fen Liu, Zhimin Zhou, Huizhen Li, Jing You
Summary: Chemicals with elevated bioaccumulation profiles pose potential risks to public health and the environment. Existing methods for bioaccumulation determination are not suitable for ionizable organic compounds (IOCs). By using the zebrafish embryo model, researchers elucidated the toxicokinetics and bioconcentration of eight IOCs with diverse traits. The results provide an understanding of the partitioning behavior of IOCs and improve predictive bioconcentration modeling.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Environmental Sciences
Teresa Balbi, Angelica Miglioli, Michele Montagna, Davide Piazza, Beatrice Risso, Remi Dumollard, Laura Canesi
Summary: The widely used biocide triclosan (TCS) is detected at high concentrations in water compartments, and it has been found to disrupt the biomineralization process in early mussel larvae.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Engineering, Environmental
Ling Zhang, Bryan W. Brooks, Fen Liu, Zhimin Zhou, Huizhen Li, Jing You
Summary: This study investigates the toxicokinetics and bioconcentration of ionizable organic compounds (IOCs) using zebrafish embryos as a model. The results show that these compounds are rapidly taken up and cleared in zebrafish, indicating their readily bioavailability in ionized forms. Predictive bioaccumulation models were constructed based on the human pharmacokinetic proportionality factor, apparent volume of distribution (V-D), and validated using hydrophobicity-based parameters. The study highlights the utility of biologically based ''read-across'' approaches for predicting bioaccumulative potential of IOCs.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Microbiology
Ning Tang, Pianpian Fan, Xiaogang Yu, Rui Ma, Yexuan Tao, Weiye Wang, Fengxiu Ouyang
Summary: Long-term exposure to high concentration of TCS may reduce the diversity and alter the composition of microbiota in the gastrointestinal tract of zebrafish, while short-term exposure has a minor impact.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Engineering, Environmental
J. Sanz-Landaluze, M. Pena-Abaurrea, R. Munoz-Olivas, C. Camara, L. Ramos
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2015)
Article
Environmental Sciences
S. Zarco-Fernandez, A. M. Coto-Garcia, R. Munoz-Olivas, J. Sanz-Landaluze, S. Rainieri, C. Camara
Article
Environmental Sciences
N. Molina-Fernandez, C. Perez-Conde, S. Rainieri, J. Sanz-Landaluze
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2017)
Article
Toxicology
Alejandro Barranco, Laura Escudero, Jon Sanz Landaluze, Sandra Rainieri
JOURNAL OF APPLIED TOXICOLOGY
(2017)
Article
Environmental Sciences
S. Zarco-Fernandez, A. Garcia-Garcia, J. Sanz-Landaluze, C. Pecheyran, R. Munoz-Olivas
Article
Chemistry, Analytical
Gustavo Moreno-Martin, Jon Sanz-Landaluze, Maria Eugenia Leon-Gonzalez, Yolanda Madrid
ANALYTICA CHIMICA ACTA
(2019)
Article
Environmental Sciences
Pablo Cabezas-Sanchez, Sandra Rainieri, Nadia Conlledo, Alejandro Barranco, Jon Sanz-Landaluze, Carmen Camara, Jose L. Luque-Garcia
Article
Environmental Sciences
Gustavo Moreno-Martin, Jon Sanz-Landaluze, Maria Eugenia Leon-Gonzalez, Yolanda Madrid
SCIENCE OF THE TOTAL ENVIRONMENT
(2020)
Article
Environmental Sciences
Beatriz Gomez-Gomez, Jon Sanz-Landaluce, Ma Teresa Perez-Corona, Yolanda Madrid
SCIENCE OF THE TOTAL ENVIRONMENT
(2020)
Article
Chemistry, Multidisciplinary
Elena Rodriguez-Rodriguez, Marta Sanchez-Paniagua, Jon Sanz-Landaluze, Maria Moreno-Guzman
JOURNAL OF CHEMICAL EDUCATION
(2020)
Article
Chemistry, Analytical
Gustavo Moreno-Martin, Jon Sanz-Landaluze, Maria Eugenia Leon-Gonzalez, Yolanda Madrid
Summary: The biotransformation of selenium compounds into volatile organoselenium species is influenced by the type of bacterial species and chemical form of selenium. E. coli can convert selenite and Ch-SeNPs into different organoselenium compounds, while S. aureus is limited in its conversion abilities. Additionally, the formation of a new volatile mixed sulfur/selenium compound, dimethyl selenenyl sulfide, from nanoparticulated selenium has been detected for the first time.
Article
Biochemical Research Methods
Noemi Molina-Fernandez, Sandra Rainieri, Riansares Munoz-Olivas, Paloma de Oro-Carretero, Jon Sanz-Landaluze
Summary: Antidepressant drugs are widely used for treating disorders like depression, with their presence and metabolites found in the environment. Research showed low bioaccumulation of these compounds in zebrafish, but evidence of metabolite transformation was observed after 6 hours of exposure.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2021)
Article
Environmental Sciences
Paloma De Oro-Carretero, Jon Sanz-Landaluze
Summary: This study evaluates the bioaccumulation and biotransformation of BDE-47 using zebrafish eleutheroembryos and develops an effective analytical method. The results show that BDE-47 has the ability to be rapidly absorbed and heavily accumulated, and can be transformed into its metabolites BDE-28, 2'-OH-BDE-28, and 5-MeO-BDE-47. The study demonstrates the feasibility of using zebrafish eleutheroembryos for bioaccumulation and metabolic studies.
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
(2023)
Article
Environmental Studies
Marian Simon-Rojo, Ines Morales Bernardos, Jon Sanz Landaluze
Article
Chemistry, Multidisciplinary
Noemi M. Fernandez, Ana M. Coto-Garcia, Raquel Gonzalo-Lumbreras, Jon Sanz-Landaluze, Concepcion Perez-Conde, Carmen Camara
CURRENT GREEN CHEMISTRY
(2016)