Article
Chemistry, Analytical
Shalene Xue Lin Goh, Esther Xue Yi Goh, Hian Kee Lee
Summary: A novel membrane-based SPE-UHPLC-MS/MS method was developed for the determination of nine glucocorticoids in water, with the use of SDS-MWCNTs material and membrane device, enhancing the overall extraction efficiency.
Article
Chemistry, Applied
Jingjing Du, Xiaowei Li, Lu Tian, Jing Li, Chengfei Wang, Dongyang Ye, Liang Zhao, Saiwa Liu, Jian Xu, Xi Xia
Summary: A simple and reliable analytical method was developed for the simultaneous determination of 11 macrolides in swine, chicken, bovine, and sheep tissues, as well as eggs. The method showed high recoveries and low relative standard deviations.
Article
Chemistry, Applied
Zhenzhen Yao, Jixin Liu, Xuefei Mao, Guoying Chen, Zhihong Ma, Bingru Li
Summary: For the first time, separation and analysis of Hg2+ and methylmercury was achieved using in-line SPE-LC-AFS. The method was easy, compact, robust, and sensitive in mercury speciation analysis, ensuring food safety.
Article
Biochemical Research Methods
Jing Yang, Xinzhong Zhang, Xuemei Wang, Hulin Wang, Jiali Zhao, Zheng Zhou, Xinzhen Du, Xiaoquan Lu
Summary: In this study, a magnetic composite MIL-101(γ-Fe2O3)/MWCNTs was successfully synthesized and used as an adsorbent for enhanced and rapid enrichment of trace polycyclic aromatic hydrocarbons (PAHs). The adsorption process was well described by the pseudo-second-order kinetic model and Langmuir isotherm model. A sensitive detection method was established and showed wide linear range, low detection limits, and high enrichment factors for PAHs.
JOURNAL OF CHROMATOGRAPHY A
(2022)
Article
Chemistry, Analytical
Zixuan Ding, Kouhua Zhang, Wenjuan Yang, Qiang Fu, Li Jia
Summary: In this study, magnetic multi-walled carbon nanotubes (MMWCNTs) were prepared and used as the adsorbent of magnetic solid-phase extraction (MSPE) to extract NEOs. MMWCNTs showed good adsorption performance towards NEOs, with adsorption capacities of 18.4, 25.9, and 18.4 mg g-1 for imidacloprid, thiacloprid, and acetamiprid, respectively. The adsorption process took 20 minutes. The combination of MMWCNTs-based MSPE method and field-enhanced sample stacking-capillary electrophoresis (FESS-CE) enabled sensitive detection of NEOs.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Aysu Arman, Sener Saglam, Aysem Uzer, Resat Apak
Summary: An electrochemical sensor was developed for direct detection of organic peroxide explosives, specifically TATP and HMTD. The sensor exhibited a distinct advantage by responding to intact TATP solutions in neutral medium, demonstrating excellent selectivity and sensitivity for PBE detection. The sensor also showed nonresponsive behavior to H2O2, preventing false positives from other peroxide materials commonly found in everyday use.
ANALYTICAL CHEMISTRY
(2021)
Article
Biochemical Research Methods
Nasrin Soltani, Saeed Habibollahi, Alireza Salamat
Summary: A dispersive micro-solid phase extraction method coupled with HPLC-UV was developed for the simultaneous preconcentration and determination of codeine and tramadol in human saliva. The method utilized oxidized multi-walled carbon nanotubes and zeolite Y nanoparticles as an efficient nanosorbent, and various parameters affecting the adsorption and desorption steps were investigated. Under optimized conditions, the extraction efficiencies, enrichment factors, and linear ranges for codeine and tramadol were determined. The method was successfully applied to the analysis of codeine and tramadol in saliva samples.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
(2023)
Article
Biochemical Research Methods
Pingping Wang, Fangling Wu, Fuxing Xu, Jun Jack Hu, Chuan-Fan Ding
Summary: The study developed a special poly solid-phase extraction (in-tube SPE) column for extraction analysis combined with UPLC, demonstrating excellent extraction efficiency, good precision, and satisfactory sensitivity for preservatives detection. The method is characterized by simple sample pretreatment, high throughput, rapid analysis, cost-effectiveness, and satisfactory sensitivity.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Applied
Shahnaz Teimoori, Hamid Shirkhanloo, Amir Hessam Hassani, Mostafa Panahi, Nabiollah Mansouri
Summary: An advanced synthesis method using phenylalanine and task-specific ionic liquid functionalized on multi-walled carbon nanotubes was employed to efficiently extract BTEX from milk and water samples. The extraction was performed using ultrasound-assisted dispersive homogenized-micro-solid phase extraction with extraction efficiencies ranging from 95.1% to 103.4%. The BTEX compounds were analyzed using gas chromatography with flame ionization detection, and the linear range, LOD, and LOQ for BTEX in milk and water samples were determined.
Article
Biochemical Research Methods
Ana Flavia Barbosa de Oliveira, Aline de Melo Vieira, Jandyson Machado Santos
Summary: Wastewater-based epidemiology (WBE) is an effective tool for quantifying illicit drug biomarkers (IDBs) in wastewater samples to study drug consumption. However, the different chemical properties of IDBs pose challenges in developing analytical methods for multi-analyte analysis. Recent workflows have focused on simplifying and optimizing the analytical workflows to reduce uncertainties, analysis times, and costs in quantifying IDBs. This review article provides an overview of studies published since 2020, highlighting the challenges and trends in analytical workflows for the multi-analysis of IDBs in wastewater samples.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Jiawei Hong, Xiaomei Liu, Xiuying Yang, Yousheng Wang, Longshan Zhao
Summary: An ionic liquid-based dispersive liquid-liquid microextraction combined with magnetic solid-phase extraction method was developed for extraction of quinolones from honey and milk. Satisfactory linearity and high sensitivity were achieved under optimized conditions. The proposed method can be employed for the determination of antibiotic residues in honey and milk samples.
Article
Chemistry, Physical
Praveen Kumar Singh, Prashant Dubey, Ravindra Dhar, Roman Dabrowski
Summary: The dispersion of functionalized and non-functionalized multi walled carbon nanotubes has an effect on the thermodynamic, dielectric, optical, and electro-optical properties of 40octyl-4-cyanobiphenyl, a nematic host. The transition temperature and associated enthalpy increase in the thermodynamic study. The dielectric anisotropy increases in both dispersed nano-composites compared to the pure sample. The conductivity of non-functionalized multi walled carbon nanotubes increases by 2 orders of magnitude. The optical band gap decreases in both dispersed nanocomposites, as shown by the ultraviolet-visible spectroscopy study. The electro-optical parameters vary for functionalized and non-functionalized multi walled carbon nanotubes dispersed nanocomposites.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Chemistry, Multidisciplinary
Yanmei Yang, Weiqing Wang, Zhenzhen Chen, Xiaoxiao Wang, Xia Meng, Zhenhua Wang, Heping Jiao, Lili Tong, Bo Tang
Summary: Arsenate (As(v)) is a highly toxic substance found widely in the environment. It is crucial to accurately and quickly determine the concentration of As(v). In this study, we developed a novel competitive coordination strategy using online internal extractive electrospray ionization mass spectrometry (iEESI-MS) for the quantification of ultratrace As(v). Our method showed excellent performance in detecting ultratrace As(v) directly in a wide range of samples, including solids and liquids such as food, water, and biological samples.
CHEMICAL COMMUNICATIONS
(2023)
Article
Chemistry, Physical
Recep Ustunsoy, Bircan Dinc, Muhammet Bektas
Summary: Carbon nanotubes have high absorption capabilities and can be used for water purification and removal of heavy metals and plastic originated compounds. Mult-walled carbon nanotubes show good performance in adsorbing DEP, and paramagnetic MWNTs are an effective method for extracting PAEs from liquids.
FULLERENES NANOTUBES AND CARBON NANOSTRUCTURES
(2022)
Review
Chemistry, Inorganic & Nuclear
Anna A. Kotova, Didier Thiebaut, Jerome Vial, Antoine Tissot, Christian Serre
Summary: Analytical chemistry is crucial for separating complex mixtures, and Metal-organic frameworks (MOFs) are promising porous hybrid solids with unique physico-chemical properties, which can be applied in chromatography and solid-phase extraction to address challenges in these fields.
COORDINATION CHEMISTRY REVIEWS
(2022)
Article
Biochemical Research Methods
Maria Consolacion Rodriguez-Palazon, Natalia Arroyo-Manzanares, Pilar Vinas, Ignacio Lopez-Garcia, Manuel Hernandez-Cordoba, Natalia Campillo
Summary: A new analytical method combining dispersive magnetic solid-phase extraction (DMSPE) and ultra-high-performance liquid chromatography with quadrupole-time-of-flight mass spectrometry (UHPLC-ESI-Q-TOF-MS) was developed for the preconcentration and analysis of capsaicin (CAP), dihydrocapsaicin (DCAP), and N-vanillylnonanamide (PCAP) in human serum samples. The use of magnetic multiwalled carbon nanotubes as the adsorbent material yielded the best results. The method was validated by achieving good linearity and low detection limits, and it was also applied for the identification of capsaicinoid metabolites and related compounds in the serum samples.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Yesica Vicente-Martinez, Maria Jose Munoz-Sandoval, Manuel Hernandez-Cordoba, Ignacio Lopez-Garcia
Summary: Due to the toxicity of mercury, it is necessary to implement analytical procedures that can quantify the different forms of mercury in the environment, even at low concentrations. Additionally, it is desirable for the procedures to distinguish between these forms due to their various environmental and health consequences. This study proposes a dispersive solid-phase microextraction method using a magnetic hybrid material formed by graphene oxide and ferrite (Fe3O4@GO) as the adsorbent, followed by determination using electrothermal atomic absorption spectrometry (ETAAS).
Article
Biochemical Research Methods
Natalia Arroyo-Manzanares, Maria Garcia-Nicolas, Fuensanta Abellan-Alfocea, Laura Prieto-Baeza, Natalia Campillo, Blanca del Val Oliver, Jose Zarauz-Garcia, Luis Saenz, Pilar Vinas
Summary: In this study, an untargeted metabolomic strategy based on the monitoring of volatile compounds in serum was proposed as a complementary, fast, and efficient test for inflammatory bowel disease (IBD) patient diagnosis. Serum samples including IBD patients and healthy volunteers were collected, and a chemometric model was built to achieve IBD diagnosis, obtaining a 100% classification rate.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Maria Garcia-Nicolas, Natalia Arroyo-Manzanares, Natalia Campillo, Carolina Reyes-Palomo, Santos Sanz-Fernandez, Jose Fenoll, Vicente Rodriguez-Estevez, Pilar Vinas
Summary: This study proposes an analytical methodology combining dispersive magnetic solid-phase extraction (DMSPE) and liquid chromatography-mass spectrometry (LC-MS) to explore the occurrence of 13 mycotoxins in natural grass samples. The method was validated and optimized for the adsorption and desorption steps of DMSPE. The analysis of 83 natural grass samples revealed the presence of enniatin B and enniatin B-1 in all samples, with various concentrations. Co-occurrence of multiple mycotoxins was also observed in the samples.
Article
Biochemistry & Molecular Biology
Yesica Vicente-Martinez, Maria Jose Munoz-Sandoval, Manuel Hernandez-Cordoba, Ignacio Lopez-Garcia
Summary: A solid-phase dispersive microextraction method using ferrite as an adsorbent was developed for separating and determining Ga(III) and In(III) ions. The ions were adsorbed onto the ferrite, which was easily collected with a magnet. The analytes were desorbed and measured using electrothermal atomic absorption spectrometry. The procedure showed high enrichment factor and low detection limits, and it was verified with standard reference materials and standard additions. The method could potentially be used for recovering valuable elements from different matrices for reuse.
Article
Biochemistry & Molecular Biology
Ana Castell, Natalia Arroyo-Manzanares, Yolanda Guerrero-Nunez, Natalia Campillo, Pilar Vinas
Summary: The botanical origin of honey significantly affects its composition and properties. This study used headspace gas chromatography coupled with mass spectrometry to characterize honey samples from 11 different botanical origins in Spain. The analysis identified 27 volatile compounds, and the samples were classified into five categories based on their botanical origins. The proposed methodology achieved accurate classification of honey samples and could be helpful in determining the authenticity of honey.
Article
Spectroscopy
Ignacio Lopez-Garcia, Maria J. Munoz-Sandoval, Manuel Hernandez-Cordoba
Summary: Silver nanoparticles (AgNPs) and gold nanoparticles (AuNPs) can be extracted from their ions using magnetic dispersive micro-solid phase extraction with non-functionalised ferrite particles. The extraction is based on controlling the acidity of the medium, without involving oxidation-reduction processes. The analytes are desorbed and determined by electrothermal atomization atomic absorption spectrometry. The method has a high enrichment factor, low detection limits, and good reproducibility.
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY
(2023)
Article
Food Science & Technology
Maria Garcia-Nicolas, Natalia Arroyo-Manzanares, Pilar Vinas
Summary: Dispersive magnetic solid-phase extraction (DMSPE) technique combined with high-resolution mass spectrometry and liquid chromatography analysis can be used for sensitive and effective sample treatment of aflatoxins in paprika samples.
Article
Chemistry, Analytical
Maria Garcia-Nicolas, Maria Carmen Perez-Alvarez, Fuensanta Abellan-Alfocea, Natalia Arroyo-Manzanares, Natalia Campillo, Blanca del Val-Oliver, Enrique Jimenez-Santos, Jose Zarauz-Garcia, Luis Saenz, Pilar Vinas
Summary: Inflammatory bowel disease (IBD) is an immune-mediated disease characterized by chronic mucosal inflammation of the digestive tract. This study presents a rapid and reliable diagnostic complementary test for patients with IBD by monitoring the volatile compound fingerprint of serum and urine. The method allows the differentiation between healthy and IBD patients and between different IBD status (remission or active) using integrated markers present in the samples.
Article
Chemistry, Analytical
Claudia Gimenez-Campillo, Marta Pastor-Belda, Natalia Arroyo-Manzanares, Natalia Campillo, Blanca del Val Oliver, Jose Zarauz-Garcia, Luis Saenz, Pilar Vinas
Summary: Pteridines are compounds involved in the metabolism of cofactors and vitamins, and their concentration in urine can be altered by diseases such as cancer or inflammatory bowel disease. A method using high-performance liquid chromatography coupled to mass spectrometry was developed to analyze the concentration of lumazines and pterins in urine samples. The method showed excellent linearity, sensitivity, and precision parameters. The pteridine profile was related to faecal calprotectin levels, but no correlation was found. Significant differences in pteridine levels were observed between healthy subjects and patients with various diseases.
Article
Chemistry, Analytical
Maria Consolacion Rodriguez-Palazon, Natalia Arroyo-Manzanares, Natalia Campillo, Pilar Vinas
Summary: This study presents a method combining dispersive liquid-liquid microextraction (DLLME) with ultra-high performance liquid chromatography and quadrupole time-of-flight mass spectrometry (UHPLC-Q-TOF-MS) for the simultaneous determination of four aromatic biogenic amines (BAs) in human urine. The method achieved the highest extraction efficiency by employing a derivatization step with dansyl chloride. The limits of detection ranged from 0.54 to 3.6 μg/L. The method exhibited precision of 3.4-10.2% and trueness of 93.6-114%. Analysis of nine urine samples revealed TYR concentrations between 52 and 304 μg/L. Non-targeted analysis did not detect other BAs or related metabolites.
Article
Chemistry, Analytical
Lixy Leon-Moran, Marta Pastor-Belda, Natalia Campillo, Natalia Arroyo-Manzanares, Carmen Torres, Pilar Vinas
Summary: This study aimed to develop a novel analytical method for the determination of metabolites of persistent organic pollutants in human tissues. The method achieved good precision and demonstrated no detection of the target compounds in the studied samples.
JOURNAL OF SEPARATION SCIENCE
(2023)
Article
Biochemical Research Methods
Ana Castell, Natalia Arroyo-Manzanares, Rosa Palma-Manrique, Natalia Campillo, Carmen Torres, Jose Fenoll, Pilar Vinas
Summary: In this study, a comprehensive investigation of the distribution of emerging mycotoxins in the human body was conducted. A new analytical method was proposed and applied to 26 forensic autopsy cases, revealing the bioaccumulation of these mycotoxins in various tissues. The findings contribute to our understanding of the potential health effects of these emerging mycotoxins on humans.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)