Article
Chemistry, Applied
Su Han Wang, Ning Ma, Xiao Huan Zang, Shuai Hua Zhang, Jian Ping Wang, Ning Peng Wu
Summary: In this study, a composite material was synthesized by polymerizing molecularly imprinted microspheres on the surface of graphitic carbon nitride. The composite was used for purification of fluoroquinolones in chicken muscle, showing high absorption capacities and recoveries, and could be reused multiple times.
FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT
(2022)
Article
Chemistry, Applied
Zhaoyuan He, Yawen Guo, Lan Chen, Kaizhou Xie, Yang Lu, Jinyuan Chen, Genxi Zhang, Tao Zhang, Guojun Dai
Summary: A sensitive and efficient UPLC-FLD method was developed for detecting TC, OTC, DOX, ENR, and CIP residues in chicken muscle. The method involved liquid-liquid extraction and solid-phase extraction for sample preparation, followed by chromatographic separation using an ACQUITY UPLC BEH C18 column. The method showed good recovery rates and low RSD values, and was successfully applied to commercial chicken samples.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2022)
Article
Chemistry, Analytical
Reyla A. S. Dias, Eliane R. Sousa, Gilmar S. Silva, Lanna K. Silva, Arlan S. Freitas, Diana L. D. Lima, Erika M. L. Sousa
Summary: This study developed an HPLC-FLD methodology for the separation of fluoroquinolones and optimized the DLLME process for clean-up and preconcentration of enrofloxacin in water samples. The method showed successful results in samples with low salinity content.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
Sayed Mohamed Derayea, Mahmoud Ahmed Omar, Mohamed Abdelkhalek Hammad, Yasser Farag Hassan, Khalid M. Badr El-Din
Summary: A simple, sensitive, rapid, and specific spectroftuorimetric procedure was developed for the analysis of fluoroquinolones in Pharmaceuticals and biological fluids. The method showed good linearity, low detection limits, and excellent accuracy for the determination of different drugs.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
Ibraam E. Mikhail, Heba Elmansi, Fathalla Belal, Adel Ehab Ibrahim
Summary: Two novel, simple, sensitive, and environmentally friendly methods were developed and validated for the determination of FAV, an antiviral agent used to treat COVID-19 infections. These methods, based on solvent-free micellar LC and spectrofluorimetry techniques, were successfully applied to marketed tablet dosage forms and spiked human plasma samples. Assessment based on greenness metrics (GAPI and AGREE) confirmed their eco-friendly properties.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
Weiwen Huang, Yichen Wang, Lumei Wang, Chaoqiang Pan, Guoqing Shen
Summary: The colorimetric method presented in this study involves the use of an unmodified CIP-aptamer and gold nanoparticles for the detection of antibiotic ciprofloxacin in aqueous solutions. The method allows for quantification of the concentration of CIP through changes in absorption, showing a good linear response in a certain concentration range. Ultimately, this proposed aptasensor demonstrates great potential for application in determining CIP in water samples.
ANALYTICAL METHODS
(2021)
Article
Spectroscopy
Sherin F. Hammad, Samah F. El-Malla, Basma Z. El-Khateeb
Summary: A highly sensitive micellar spectrofluorimetric method (Method I) and a green cyclodextrin-modified micellar liquid chromatographic method (Method II) were developed and validated for the determination of diphenylpyraline HCl in pharmaceutical tablets and in plasma. Method I allowed for the determination of diphenylpyraline in plasma at the nano-level, while Method II allowed for the simultaneous determination of diphenylpyraline, paracetamol, and caffeine with enhanced spectrofluorimetric detection.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Chemistry, Multidisciplinary
Yue Wang, Yuan Xu, Ruixia Gao, Xuemeng Tian, Jake Heinlein, Sameer Hussain, Lisa D. Pfefferle, Xiaoyi Chen, Xiaojing Zhang, Yi Hao
Summary: This study develops lightweight hollow double-layer hybrid magnetic molecularly imprinted polymers (HD-MMIPs) using green and sustainable chemistry, which improved the adsorption capacity and the rebinding rate of tetracycline (TC) compared to traditional surface molecularly imprinted polymers (SMIPs). The Fe3O4 nanoparticles embedded in the HD-MMIPs significantly facilitated the separation process. The HD-MMIPs also showed potential in monitoring and controlling TC contamination in real samples.
Article
Chemistry, Multidisciplinary
Qingbao Yang, Yanhua Qi, Jingming Zhou, Yumei Chen, Chao Liang, Zhanxiang Liu, Xiaoli Zhang, Aiping Wang
Summary: A novel fluorescent immunochromatographic assay based on quantum dots was developed for the detection of fleroxacin residues in pork meat, showing good accuracy and specificity.
Review
Food Science & Technology
Maranda S. Cantrell, Owen M. McDougal
Summary: Acrylamide is a product of the Maillard reaction found in starchy, asparagine-rich foods processed at high temperatures, which has been identified in certain food and beverage products. Research suggests that high levels of acrylamide ingestion may pose potential health risks. Regulatory measures have been implemented in the EU and California to require disclosure of acrylamide presence in fried, baked foods, and coffee.
COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY
(2021)
Article
Chemistry, Analytical
Lu Lin, Shanshan Song, Xiaoling Wu, Liqiang Liu, Hua Kuang, Jing Xiao, Chuanlai Xu
Summary: This study developed an ic-ELISA and immunochromatographic strip assay for rapid screening of robenidine hydrochloride (ROBH), showing high specificity and good recovery rates. Both methods yielded results consistent with LC-MS/MS analysis, making them effective for detecting ROBH in shrimp, chicken breast, and chicken liver samples.
Article
Food Science & Technology
Belete Eshetu Gebreyohannes, Simiso Dube, Mathew Muzi Nindi
Summary: A method for the simultaneous determination of a mixture of food contaminants in solid biological samples (chicken liver) using dispersive liquid-liquid microextraction/liquid chromatography-high resolution mass spectrometry (DLLME/LC-HRMS) is presented. The method was validated with good linearity, recovery rates, and low detection limits for a range of contaminants. The results of this study showed no significant difference between the developed method and the standard solid phase extraction (SPE) method.
Article
Food Science & Technology
Masaru Usui, Sho Tateno, Masanobu Onozaki, Naoaki Misawa, Yasuhiko Suzuki, Yutaka Tamura, Chie Nakajima
Summary: The rapid method CAMERA can simultaneously detect C. jejuni/coli and determine their susceptibility to fluoroquinolone/macrolide drugs. This study demonstrated the accuracy and efficiency of CAMERA in detecting and confirming antimicrobial resistance, providing a valuable tool for surveillance and control of resistant C. jejuni/coli contamination.
Article
Multidisciplinary Sciences
Aleksandr L. Kim, Egor Musin, Alexey Dubrovskii, Sergey A. Tikhonenko
Summary: Sodium dodecyl sulfate (SDS) is widely used as an anionic surfactant, but its frequent use leads to environmental pollution and negative effects on living organisms. Therefore, there is a need for cheap and fast detection methods for SDS in wastewater and surface waters. It has been discovered that SDS can destroy polyelectrolyte microcapsules, leading to the proposal of using these microcapsules to create qualitative and quantitative diagnostic systems for SDS determination. The systems involve fluorescence intensity measurement and turbidimetry, and can detect SDS concentrations in the range of 10 to 50 μg/mL.
SCIENTIFIC REPORTS
(2022)
Article
Chemistry, Multidisciplinary
Aynalem Lakew, Teshome Assefa, Meseret Woldeyohannes, Negussie Megersa, Bhagwan Singh Chandravanshi
Summary: In this study, a sensitive and reliable liquid chromatography with UV detection method was developed for the simultaneous determination of seven multiclass antibiotic residues in chicken tissues. The method showed good linearity, precision, sensitivity, accuracy, and robustness. It is the first instance of simultaneous determination of seven multiclass, multi-residues analysis using LC-UV from chicken tissue samples.
Review
Biochemistry & Molecular Biology
Angelina Pena, Sofia Duarte, Andre M. P. T. Pereira, Liliana J. G. Silva, Celia S. M. Laranjeiro, Marta Oliveira, Celeste Lino, Simone Morais
Summary: This study reviews the human biomonitoring data on mycotoxins detected in the Portuguese population and analyzes the exposure patterns and potential health risks. By addressing the difficulties and challenges of HBM studies in Portugal, this research aims to support national and European health policies.
Review
Biochemistry & Molecular Biology
Angelina Pena, Sofia Duarte, Andre M. P. T. Pereira, Liliana J. G. Silva, Celia S. M. Laranjeiro, Marta Oliveira, Celeste Lino, Simone Morais
Summary: This study presents a comprehensive review of human biomonitoring data in Portugal, focusing on the concentrations of polycyclic aromatic hydrocarbons, metals, metalloids, and pesticides in different biological matrices. The analysis of these data allows for an assessment of the exposure patterns and potential health risks among the Portuguese population. Additionally, the study identifies the main difficulties and challenges in conducting human biomonitoring studies and aims to support national and European policies promoting human health.
Article
Pharmacology & Pharmacy
Ines Garcia, Diana Valente, Nuno Carolino, Helder Dinis, Rui Sousa, Sofia C. Duarte, Liliana J. G. Silva, Andre M. P. T. Pereira, Angelina Pena
Summary: The Azorean dairy industry is affected by the proliferation of fungi and mycotoxin contamination in the feed. This can result in reduced reproductive performance and decreased productivity and quality of milk produced. It is important to implement strategies to reduce mycotoxin concentration and monitor their levels in food.
Article
Food Science & Technology
Liliana J. G. Silva, Andre M. P. T. Pereira, Sofia Duarte, Ines Pedro, Catarina Perdigao, Alexandra Silva, Celeste M. Lino, Anabela Almeida, Angelina Pena
Summary: Rice is a crucial staple crop for billions of people, but its consumption can lead to exposure to chemical contaminants such as mycotoxins and metalloids. This study evaluated the presence and human exposure to AFB1, OTA, ZEN, and InAs in Portuguese rice samples. AFB1 was found in 4.8% of the samples, exceeding the European MPL, while ZEN was present in 88.89% of the samples. InAs was detected in all samples, but none exceeded the MPL. There was no correlation between mycotoxin and InAs contamination. AFB1 exceeded the provisional maximum tolerable daily intake, with children being the most vulnerable group.
Article
Food Science & Technology
Ana Rita Soares Mateus, Carmen Crisafulli, Matilde Vilhena, Silvia Cruz Barros, Angelina Pena, Ana Sanches Silva
Summary: Herbal infusions are popular beverages known for their health benefits and antioxidants. This study developed a method to determine tropane alkaloids in herbal infusions, while also evaluating their antioxidant capacity. The presence of atropine in one of the samples exceeded the European regulation. Yerba mate, lemon balm, and peppermint were found to have high antioxidant capacity.
Article
Chemistry, Multidisciplinary
Andre Pereira, Etiele Greque de Morais, Liliana Silva, Angelina Pena, Andreia Freitas, Margarida Ribau Teixeira, Joao Varela, Luisa Barreira
Summary: Urban wastewaters contain pharmaceuticals that are not effectively removed in conventional treatments, limiting water reuse. This study assessed pharmaceutical removal in a pilot-scale microalgal tertiary treatment under real conditions. Even after secondary treatment, the water still had measurable amounts of pharmaceuticals (average of 218.4 ng/L) that significantly decreased to 39.83 ng/L at the exit of the microalgal system. Antibiotics and antipsychotics showed better removal rates (88.8% and 86.4%, respectively) compared to antihypertensives (75.3%) and others (Bezafibrate and Diclofenac; 64.0%). Physical and chemical characteristics of the wastewater influenced pharmaceutical removal.
APPLIED SCIENCES-BASEL
(2023)
Article
Food Science & Technology
Rui R. Martins, Andre M. P. T. Pereira, Liliana J. G. Silva, Alexandra Esteves, Sofia C. Duarte, Andreia Freitas, Angelina Pena
Summary: This study aimed to evaluate the presence of nine coccidiostats in 62 egg samples using UHPLC-MS/MS. The results showed that only diclazuril and nicarbazin were detected, with nicarbazin being more frequently detected. Home-raised eggs had higher levels of nicarbazin compared to diclazuril. Overall, consumers' health should not be adversely affected by egg consumption.
Article
Infectious Diseases
Anabela Almeida, Cristina De Mello-Sampayo, Ana Lopes, Rita Carvalho da Silva, Paula Viana, Leonor Meisel
Summary: The release of antimicrobial pharmaceuticals in the environment is a significant concern due to ecological impacts and microbial resistance. This study found that rifaximin and atovaquone are likely to pose potential ecotoxicological risks to aquatic organisms, while flucloxacillin, piperacillin, tazobactam, meropenem, ceftriaxone, fosfomycin, and metronidazole have the highest potential for antibiotic resistance in all analysed regions.
Article
Infectious Diseases
Andre M. P. T. Pereira, Andreia Freitas, Angelina Pena, Liliana J. G. Silva
Summary: The presence of pharmaceuticals, particularly antibiotics, in aquatic ecosystems can have significant negative impacts on natural ecosystems. Bivalves are ideal sentinel species for biomonitoring environmental health hazards in coastal and estuarine ecosystems due to their ability to filter water and bioconcentrate chemicals. An analytical strategy was developed to assess the occurrence of antibiotics as emerging pollutants in aquatic environments, and the method was validated for 43 antibiotics according to European regulations.
Review
Infectious Diseases
Rita Carvalho da Silva, Leonor Meisel, Noemia Farinha, Orlanda Povoa, Cristina De Mello-Sampayo
Summary: Some ectoparasites transmit illness-causing bacteria and viruses, leading to excessive use of antimicrobials for treatment. Therefore, it is crucial to control ectoparasites in a sustainable way. Ethnobotanical survey data was analyzed to identify plants used as ectoparasiticides in companion animals and livestock. Plants such as Juglans regia, Daphne gnidium, and Ruta graveolens were identified as potential veterinary ectoparasiticides. This research also highlights the traditional use of Plantago lanceolata and Cistus populifolius as ectoparasiticides for the first time. Ultimately, these plant-derived veterinary ectoparasiticides could help reduce antimicrobial use.
