期刊
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
卷 396, 期 1, 页码 199-203出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s00216-009-3086-0
关键词
Glycoproteome; Enrichment; Carbohydrate; Glycosylation
Glycosylation is, by far, one of the most common and important post-translational modifications and becomes a target for proteomic research. A key challenge in glycoproteome research is the development of fast and effective enrichment strategies for high-throughput glycosylation analysis. Different kinds of glycan-capturing anchors have been developed and successfully applied to glyco-specific enrichment in large-scale glycosylation identification in the past few years. In this paper, we highlight several examples on various types of enrichment methods that have been utilized to specifically capture glycopeptides/glycoproteins for subsequent mass spectrometric analysis.
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