Article
Chemistry, Analytical
Fengjian Chu, Wei Wei, Nazifi Sani Shuaibu, Hongru Feng, Xiaozhi Wang, Yuanjiang Pan
Summary: Sensitive and accurate detection of biomolecules is crucial for various applications. Mass spectrometry has emerged as an ideal technique due to its high sensitivity, throughput, and resolution. This review summarizes three main approaches for mass spectrometry sensing and biopsy techniques, including array biosensing, probe/pen-based mass spectrometry, and other biosensor-mass spectrometry coupling techniques. The portability and practicality of these methods are discussed, along with potential future directions to advance biomolecular identification and rapid detection of real biological samples using mass spectrometry.
Article
Chemistry, Analytical
Nikita P. Bacalzo, Garret Couture, Ye Chen, Juan J. Castillo, Katherine M. Phillips, Naomi K. Fukagawa, Carlito B. Lebrilla
Summary: A novel method for high-throughput and quantitative analysis of polysaccharides in food samples was developed, successfully quantifying nine polysaccharides with sufficient accuracy and reproducibility. Varied concentrations of polysaccharides were observed in different food samples, highlighting the potential implications for understanding the interactions of dietary polysaccharides, gut microbial community, and human health.
ANALYTICAL CHEMISTRY
(2022)
Article
Immunology
Mirelle Garcia Silva-Bailao, Patricia de Sousa Lima, Manoel Marques Evangelista Oliveira, Lua Cardoso Oliveira, Rodrigo Almeida-Paes, Clayton Luiz Borges, Alexandre Melo Bailao, Alexandre Siqueira Guedes Coelho, Celia Maria de Almeida Soares, Rosely Maria Zancope-Oliveira
Summary: This study used a nanoscale liquid chromatography coupled with tandem mass spectrometry approach to analyze the yeast proteomic profiles of S. brasiliensis, S. schenckii, and S. globosa, revealing differentially expressed proteins related to carbohydrate and amino acid metabolism. The findings suggest that S. brasiliensis has a distinct metabolism compared to S. schenckii and S. globosa, potentially explaining its more virulent character. The data provided new insights into Sporothrix species metabolism and may be useful for future functional studies.
MICROBES AND INFECTION
(2021)
Article
Engineering, Environmental
Kelly L. Pereira, Martyn W. Ward, John L. Wilkinson, Jonathan Brett Sallach, Daniel J. Bryant, William J. Dixon, Jacqueline F. Hamilton, Alastair C. Lewis
Summary: This study presents an automated method for non-targeted compositional analysis of environmental matrices, which has been rigorously tested for reliability and reproducibility using authentic standards. The method detected over 9600 compounds from critical pollutant sources in environmental samples, demonstrating its ability for rapid and comprehensive compound detection.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2021)
Article
Chemistry, Analytical
Sakshi Gautam, Alireza Banazadeh, Byeong Gwan Cho, Mona Goli, Jieqiang Zhong, Yehia Mechref
Summary: Researchers successfully achieved efficient separation of glycan isomers using mesoporous graphitized carbon (MGC) material in a 1 cm-long column, showing reproducibility and stability in both capillary columns and packed nanospray emitters.
ANALYTICAL CHEMISTRY
(2021)
Article
Agriculture, Multidisciplinary
Toshihiro Sakurai, Zhen Chen, Arisa Yamahata, Takahiro Hayasaka, Hiroshi Satoh, Hirotaka Sekiguchi, Hitoshi Chiba, Shu-Ping Hui
Summary: This study showed that a short-term high carbohydrate diet could significantly impact the levels of CL and MLCL in the liver of mice, leading to mitochondrial dysfunction.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2021)
Article
Chemistry, Physical
Faezeh Ghorbanizamani, Hichem Moulahoum, Emine Guler Celik, Suna Timur
Summary: The pursuit of novel materials and enhanced analytical efficiency in biomaterial engineering has led to a strong interest in hydrogels and ion gels for biosensing applications. This review provides an overview of these two materials and highlights recent impactful research in the field.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Biochemical Research Methods
Edvaldo Vasconcelos Soares Maciel, Fernando Mauro Lancas
Summary: This study presents a method that combines solid-packed cartridges and capillary LC-MS to integrate sample preparation and analytical steps. The proposed method effectively extracts and analyzes selected pesticides in soil samples, with potential applications in other solid samples. Initial qualitative tests on pesticides in honeybees were also conducted.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Review
Chemistry, Analytical
Ozge Selcuk, Yeliz Demir, Cem Erkmen, Sercan Yildirim, Bengi Uslu
Summary: Viruses are the main pathogenic substances causing severe diseases in humans and other living things, leading to the emergence of antiviral drugs for prevention and treatment. This review provides an overview of the analysis of currently used antiviral drugs from 2010 to 2021, focusing on chromatographic, spectrometric, and electrochemical methods.
CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Thais Pontes Pereira Mendes, German Sanz Lobon, Leomir Aires Silva Lima, Nayane Karla Melo Guerra, Gustavo Almeida Carvalho, Elis Marra Madeira Freitas, Mauro Cunha Xavier Pinto, Igor Pereira, Boniek Gontijo Vaz
Summary: This study presents a novel method using pencil graphite rods for mass spectrometry analysis of various analytes, such as creatinine in human urine samples. The method was optimized and successfully applied for analyzing different samples, demonstrating its potential for use in analytical chemistry and biosensors.
MICROCHEMICAL JOURNAL
(2021)
Article
Food Science & Technology
Guojian Wu, Huimin Qiu, Xin Liu, Pengjie Luo, Yongning Wu, Yizhong Shen
Summary: This review discusses the application of nanomaterials-based fluorescent assays in the detection of pathogenic bacteria. It highlights the progress in using functionalized nanoparticles for pathogenic bacteria detection. It emphasizes the advantages of nanomaterials-based fluorescent assays, such as shorter detection time and higher sensitivity compared to traditional methods.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Yuzhu Guo, Michael Forbush, Thomas R. Covey, Lucien Ghislain, Chang Liu
Summary: Acoustic ejection mass spectrometry (AEMS) is a novel high-throughput analytical technology with high reproducibility and no observed carryover; it eliminates the chromatography step and is widely used for automated liquid-liquid extraction in sample cleanup, offering simplified sample preparation and higher analytical throughput.
Article
Chemistry, Analytical
R. Rola, K. Kowalski, T. Bienkowski, J. Witwicki, S. Studzinska
Summary: The study demonstrated the utility of DBS samples in assessing newborns' vitamin D levels, comparing them to maternal and cord blood-derived serum tests. Results showed that DBS could be used interchangeably with cord blood-derived serum to determine vitamin D status in neonates, simplifying the screening process.
MICROCHEMICAL JOURNAL
(2021)
Article
Biochemical Research Methods
Masato Taoka, Kota Kamei, Akiko Kashima, Yuko Nobe, Takahiro Takekiyo, Takamasa Uekita, Tohru Ichimura
Summary: Many ion channels and receptor proteins are potential targets for new drugs. This study presents a novel proteomic sample preparation platform that allows for the processing of sub-microgram level starting materials using an ionic liquid-based sample preparation strategy and an in-StageTip technique. This approach enables the rapid solubilization and analysis of integral membrane proteins from human samples, surpassing the performance of conventional methods.
ANALYTICAL BIOCHEMISTRY
(2023)
Review
Chemistry, Analytical
Junqiao Wang, Jing Zhao, Shaoping Nie, Mingyong Xie, Shaoping Li
Summary: Carbohydrates are the most abundant organic compounds in nature, and understanding their structure properties through mass spectrometry technology is crucial for their applications, especially in characterizing herbal and food polysaccharides. The development of ionization sources and mass analysers in MS has opened up new possibilities for research in this area.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2021)
Article
Computer Science, Information Systems
Mohamed Hassaoui, Mohamed Hanini, Said El Kafhali
Summary: The use of C2 servers in cyberattacks has increased significantly, with attackers using DGA technique to hide their servers. Existing techniques for binary classification of domain names have issues with real-time detection and sensitivity to data. This paper proposes the DTFS-DGA model, which combines neural networks and traditional machine learning models to detect DGA in real-time without relying on reverse engineering and being insensitive to data size.
JOURNAL OF COMPUTER SECURITY
(2023)
Article
Chemistry, Applied
Mahmoud R. Saleh, Haitham M. El-Bery, Hani Nasser Abdelhamid
Summary: A wet-incipient impregnation method was used to synthesize hierarchical porous bimetallic (Co, Zn)-zeolitic imidazolate frameworks (ZIF-8)/TiO2 for efficient photocatalytic water splitting. Co@ZIF-8/TiO2 exhibited significantly higher photocatalytic efficiency than TiO2, with a hydrogen generation rate of 13 mmol·h(-1)·g(-1) and a 151-fold increase in catalytic performance. The hierarchical porous structure of Co@ZIF-8 facilitated charge transfer and provided efficient transport channels. This study demonstrates the potential of hierarchical porous metal-organic frameworks (MOFs) as support and promoter in photocatalytic applications of TiO2.
APPLIED ORGANOMETALLIC CHEMISTRY
(2023)
Article
Environmental Sciences
Nojood Altwaijry, Mohd Shahnawaz Khan, Gouse M. Shaik, Mohammad Tarique, Mehjbeen Javed
Summary: In this study, various parameters of oxidative stress, immune response, and abnormalities in the erythrocyte nucleus of Labeo rohita inhabiting the polluted Kshipra River, India, were measured. The heavy metal concentrations in the river water were in the order of Ni > Fe > Cd > Cr > Mn > Zn > Cu. The fish showed increased levels of antioxidant enzymes in gills, liver, and gut compared to the reference fish, but decreased levels of GST and GSH. Heavy metals also caused immunosuppression and histopathological changes in the fish. These findings highlight the potential impact of heavy metal-induced stress on fish inhabiting polluted river water and the importance of pollution control.
ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
(2023)
Article
Chemistry, Applied
Hani Nasser Abdelhamid
Summary: Metal-organic frameworks (MOFs) have shown great potential for industrial applications but current synthesis processes limit their use due to the powder form. A solvothermal method was used to grow copper-based MOFs onto a cotton textile, creating a material called CuBDC@Textile. CuBDC@Textile demonstrated excellent vapor sensing properties and high adsorption capacity for pyridine. This dual-functional material holds promise for further research on MOFs in textile applications.
APPLIED ORGANOMETALLIC CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Nojood Altwaijry, Ghaliah S. Almutairi, Mohd Shahnawaz Khan, Gouse M. Shaik, Majed S. Alokail
Summary: Amyloid fibrils accumulation can cause lethal conditions, but the use of Chlorothiazide (CTZ) can prevent or treat this disease. In this study, the effects of CTZ on hen egg white lysozyme (HEWL) aggregation were examined using various methods. The results showed that CTZ can reduce the formation of amyloid fibrils and prevent aggregation.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Mohd Shahnawaz Khan, Nojood Altwaijry, Moneera Saud Al-Bagmi, Nouf Omar Alafaleq, Majed S. Alokail, Moyad Shahwan, Anas Shamsi
Summary: Proto-oncogene tyrosine-protein kinase ROS (ROS1) is a member of a receptor family that affects epithelial cell differentiation and is highly expressed in various tumors. This study identified two potential inhibitors of ROS1 through virtual screening of phytochemicals. The findings highlight the role of ROS1 in multiple physiological processes and suggest the potential use of phytochemicals for therapeutic development targeting ROS1-associated non-small cell lung cancer.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2023)
Article
Biochemistry & Molecular Biology
Ajamaluddin Malik, Javed Masood Khan, Abdullah S. S. Alhomida, Mohammad Shamsul Ola, Majed S. S. Alokail, Mohd Shahnawaz Khan, Amal M. M. Alenad, Nojood Altwaijry, Nouf Omar Alafaleq, Hamza Odeibat
Summary: Several proteins and peptides have the ability to form amyloid fibrils, which can lead to a variety of diseases. The process by which these proteins transition from a folded and soluble state to an amyloid fibril is not well understood.
JOURNAL OF MOLECULAR RECOGNITION
(2023)
Article
Materials Science, Ceramics
Numa A. A. Althubiti, T. A. Taha, A. A. Azab, Hani Nasser Abdelhamid
Summary: The use of solid-state materials such as sodium borohydride for hydrogen storage and release can meet the requirements of the "Hydrogen Economy". This study investigated ZnO-based materials as catalysts for hydrogen release through the hydrolysis of NaBH4. The synthesis method produced nanocomposites consisting of ZnO-xTiO(2) and ZnO-xCeO(2) (x = 5 wt.% or 10 wt.%). Characterization techniques confirmed the phase purity and optical properties of the materials. The materials exhibited a high hydrogen generation rate and different activation energies.
JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Mohd Shahnawaz Khan, Nojood Altwaijry, Nasimudeen R. Jabir, Abdulaziz Mohammed Alamri, Mohammad Tarique, Azhar U. Khan
Summary: Ovarian cancer treatment is highly challenging due to the lack of clinical symptoms and sensitivity biomarkers leading to late-stage diagnosis. This study evaluated the anticancer potential of biogenic zinc oxide nanoparticles (ZnO NPs) synthesized using pumpkin seed extracts.
MOLECULAR BIOLOGY REPORTS
(2023)
Article
Chemistry, Multidisciplinary
Nouf Omar Alafaleq, Torki A. Zughaibi, Nasimudeen R. Jabir, Azhar U. Khan, Mohd Shahnawaz Khan, Shams Tabrez
Summary: This study investigates the anticancer potential of Cu-Mn bimetallic NPs synthesized from pumpkin seed extract against colon adenocarcinoma cancer cell line (HT-29). The results show significant anticancer efficacy of CMBNPs against the studied cancer cell line, with no significant cytotoxicity on normal cells.
Review
Chemistry, Medicinal
Nazia Nazam, Nasimudeen R. Jabir, Iftikhar Ahmad, Saif A. Alharthy, Mohd Shahnawaz Khan, Rashid Ayub, Shams Tabrez
Summary: Cancer is a global health problem that is on the rise, and ovarian cancer is one of the leading causes of mortality worldwide. Current treatments for ovarian cancer have limited effectiveness and come with side effects, recurrence risk, and drug resistance. Therefore, there is a need for alternative, cost-effective, and safer therapeutic strategies.
Article
Multidisciplinary Sciences
Nojood Altwaijry, Ghaliah S. Almutairi, Mohd Shahhnawaz Khan, Majed S. Alokail, Nouf Alafaleq, Rizwan Ali
Summary: Protein misfolding can lead to amyloid fiber aggregation, which is associated with various diseases. This study examines the anti-aggregating effect of Valsartan on HEWL amyloid fibrils through spectroscopy, docking, and microscopic analysis.
Article
Energy & Fuels
Moushira Saleh, Hani Nasser Abdelhamid, Dina M. Fouad, Haitham M. El-Bery
Summary: The use of light radiation to split water into hydrogen gas has great potential for green hydrogen production. A comparative study was conducted on the photocatalytic activity of TiO2 nanocomposites with two co-catalysts, Pt or Cu nanocrystals, using different synthesis methods. The study found that the deposition technique of the co-catalyst has a significant influence on the efficiency of photocatalysis for hydrogen production.
Article
Chemistry, Inorganic & Nuclear
Hani Nasser Abdelhamid, Sahar Sultan, Aji P. Mathew
Summary: 3D printing of cellulose/leaf-like zeolitic imidazolate frameworks (CelloZIF-L) allows for the creation of structures with high adsorption efficiency, capable of adsorbing carbon dioxide and heavy metals.
DALTON TRANSACTIONS
(2023)
Article
Chemistry, Multidisciplinary
Dimitrios Georgouvelas, Hani Nasser Abdelhamid, Ulrica Edlund, Aji P. Mathew
Summary: In this study, nanocellulose/alginate composite hydrogel beads were successfully prepared and modified with in situ TEMPO-mediated oxidation. The modified beads exhibited improved adsorption efficiency and water flux, making them promising candidates for large-volume, high flux water treatment.
NANOSCALE ADVANCES
(2023)
Article
Chemistry, Analytical
Yujia Ying, Huilin Li
Summary: Enzymes play a crucial role as biological catalysts in accelerating biochemical reactions in living organisms. This study proposes a convenient method for monitoring enzymatic catalytic processes using native top-down mass spectrometry. By exploring the heterogeneity of the chymotrypsin sample and using tandem mass spectrometry, the researchers were able to monitor covalent and noncovalent enzymatic complexes, substrates, and products during catalysis. The results demonstrate that this method has the potential to be a promising tool for characterizing biocatalysts.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Kang Yang, Shuaibo Shi, Jinyu Wu, Shaolong Han, Shengdi Tai, Shishen Zhang, Kun Zhang
Summary: H2O and D2O are important analogues closely related to various industries and monitoring fields. This study successfully distinguishes and detects H2O and D2O by designing a novel eu(III)-macrocycle with dual emitters, Eu-2a, and conducting fluorescence titration experiments.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Julia Kuligowski, Alvaro Perez-Rubio, Marta Moreno-Torres, Polina Soluyanova, Judith Perez-Rojas, Ivan Rienda, David Perez-Guaita, Eugenia Pareja, Ramon Trullenque-Juan, Jose Castell, Marcha Verheijen, Florian Caiment, Ramiro Jover, Guillermo Quintas
Summary: This study introduces a novel variable selection approach called cluster PLS (c-PLS) to assess the joint impact of variable groups selected based on biological characteristics on the predictive performance of a multivariate model. The usefulness of c-PLS is shown using miRNomic and metabolomic datasets obtained from the analysis of liver tissue biopsies.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Meixue Lai, Lijie Zhong, Siyi Liu, Yitian Tang, Tingting Han, Huali Deng, Yu Bao, Yingming Ma, Wei Wang, Li Niu, Shiyu Gan
Summary: This study presents a method for constructing wearable sweat electrolyte sensors using carbon fiber-based solid-contact ion-selective electrodes (SC-ISEs). By using carbon fibers extracted from commercial cloth as electrode material, the cost and reproducibility issues of flexible SC-ISEs were addressed. The results showed that the carbon fiber-based SC-ISEs exhibited reversible voltammetric and stable impedance performances, and had high reproducibility of standard potentials between normal and bending states.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Yang, Ying Liu, Min Deng, Peipei Wang, Dan Cheng, Songjiao Li, Longwei He
Summary: A near-infrared fluorescent probe has been developed to accurately measure the levels of peroxynitrite (ONOO-) in the endoplasmic reticulum (ER) in acute lung injury (ALI). The probe demonstrated rapid response, high selectivity, good sensitivity, and enhanced fluorescence intensity in response to ONOO-. It was successfully used to detect changes in ONOO- levels and showed significant increases in an ALI cell model and an ALI mouse model.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yanping Wang, Yuemei Chen, Kejun Li, Jinrong Zhou, Xin Yuan, Mei Zhang, Ke Huang
Summary: In this work, a portable analytical system based on point discharge chemical vapor generation atomic emission spectrometry (PD-CVG-AES) coupling with gold filament enrichment was designed. The highly sensitive analysis of Hg2+ indirectly realized the detection of ascorbic acid (AA). The measurement is based on the fact that Ag+ can decrease the concentration of Hg2+ by forming Ag-Hg amalgam in the presence of the reductant SnCl2, while AA can pre-reduce Ag+ to Ag0, leading to the generation of silver nanoparticles (Ag NPs). The developed novel analytical strategy broadens the application of microplasma-based AES and offers a higher level of sensitivity compared to current AA detection techniques.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yundi Huang, Bo Song, Kaiwen Chen, Deshu Kong, Jingli Yuan
Summary: This study developed two lysosome-targetable background-free TGL probes for efficient and accurate detection of 1O2, which can be used for monitoring endogenous 1O2 concentrations in lysosomes and discriminating variability induced by different photosensitizers. Furthermore, a smart luminescent sensor film was successfully prepared for on-site 1O2 production detection during PDT processes, offering a promising clinical monitoring tool for skin diseases.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Wei Lang, Jia-Mei Qin, Qian-Yong Cao
Summary: A novel polymer-based probe P1 was successfully synthesized for fluorescently ratiometric sensing of H2S with high selectivity and sensitivity. A smartphone sensing platform was constructed to conduct visual quantitative detection of H2S. P1 can be employed in evaluating the level fluctuations of H2S in living cells, testing water samples/wine samples, and monitoring food freshness.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yuanyuan Qin, Shuda Liu, Shuyun Meng, Dong Liu, Tianyan You
Summary: The study developed a split aptamer-based sandwich-type ratiometric biosensor for the detection of 17 beta-estradiol (E2) using photoelectrochemical and electrochemical assays. The biosensor utilized split aptamer fragments to recognize E2 and trigger a hybridization chain reaction, resulting in the production of double-stranded DNA labeled with CdTe quantum dots. This DNA complex was able to sensitize CdTe quantum dots and generate response signals for E2 detection. The developed biosensor demonstrated high sensitivity and accuracy with two linear ranges and low detection limits.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Siriwan Teepoo, Jongjit Jantra, Khaunnapa Panapong, David Taiwo Ajayi
Summary: A novel immunochromatographic assay based on hyperbranched Au plasmonic blackbodies with a smartphone readout was developed for rapid and sensitive detection of leucomalachite green residues in fish and shrimp products.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Andrea L. Larraga-Urdaz, Borja Moreira-Alvarez, Jorge Ruiz Encinar, Jose M. Costa-Fernandez, Maria Luisa Fernandez-Sanchez
Summary: A major challenge in the 21st century is the development of point-of-care diagnostic tools. In this study, a highly sensitive and simple bioassay using AuNPs and MNAzymes was developed for rapid detection and quantification of miRNA-4739. The proposed strategy shows potential for breast cancer diagnosis.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Xiaohan Zhao, Anyu Wang, Lingzi Zhai, Jiuhe Gao, Sizhe Lyu, Yingshan Jiang, Tian Zhong, Ying Xiao, Xi Yu
Summary: A novel method using polystyrene-coated magnetic nanoparticles for extracting monohydroxy polycyclic aromatic hydrocarbons from urine samples was investigated. The proposed method is simple, sensitive, and efficient, with desirable sensitivity for analyzing low-abundance metabolites in large volumes of complex urine samples.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Quan, Yuqing Zeng, Wenke Zhang, Fengfeng Li, Mengjiao Li, Zhihe Qing, Linlin Wu
Summary: In this study, a visual and reusable biosensor was developed for detecting substrates that are closely associated with human physiological health. The immobilized oxidase showed higher stability and sensitivity under harsh conditions, enabling reliable detection of substrates in complex fluids.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Dongjuan Wang, Xiuqian Ding, Jinling Xie, Juan Wang, Guanhao Li, Xin Zhou
Summary: In this study, a three-in-one sensor was developed for real-time detection of biogenic amines (BAs) with high sensitivity and selectivity. The sensor showed multimodal responses and could be used to fabricate portable devices for on-site non-destructive assessment of food spoilage indicators.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Jinting Meng, Zihao Xu, Shasha Zheng, Hongqun Yang, Tianfu Wang, Hong Wang, Yingwei Zhang
Summary: This study demonstrates the development of a cascade signal amplification system using a multi-pedal DNA walker and strand displacement reactions for the electrochemical detection of miRNA-155. The biosensor exhibited high sensitivity, selectivity, and the potential for clinical applications.
ANALYTICA CHIMICA ACTA
(2024)