Article
Chemistry, Analytical
Xiaojun Liu, Yuanyuan Sun, Xinyi Lin, Xiaoyan Pan, Zhangjian Wu, Hongwei Gai
Summary: This paper presents a spectral imaging-based multiplex, homogenous immunoassay that was used to detect tumor biomarkers and successfully quantify model proteins in human plasma, demonstrating the accuracy and reliability of the approach.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Xiaokun Wen, Jia Hua, Yadan Ding, Zhipeng Li, Guorui Wang, Hancheng Zhu, Jun Li, Xia Hong
Summary: A dual-mode method based on PL-RLS was developed for sensitive and accurate detection of miRNA-141. This method has a low detection limit and a linear detection range, allowing for mutual validation to ensure the accuracy and reliability of the detection results.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Analytical
Olga A. Goryacheva, Natalia Beloglazova, Irina Yu Goryacheva, Sarah De Saeger
Summary: Semiconductor quantum dots (QDs) are widely used as luminescent labels in food and medical analysis, and in combination with gold nanoparticles (GNs) as energy acceptors in Forster resonance energy transfer (FRET) pairs to develop highly sensitive biosensors. The developed homogeneous FRET-based immunoassay for detecting deoxynivalenol (DON) demonstrates the potential of fast and high-throughput mycotoxin control with a low limit of detection.
Article
Materials Science, Multidisciplinary
A. Rivera, Z. Lazcano, A. L. Gonzalez, O. Meza
Summary: This work investigates the plasmon resonances in gold and silver nanoparticles to enhance the luminescent properties of PMMA doped with different rare-earth ion densities. A rate equation model based on the Fo(r)ster theory is used to describe the luminescent dynamics between donor and acceptor rare earth ions and takes into account the electric field changes due to metallic nanoparticles. The results show that the luminescence of rare earth can be increased in the proximity of spherical gold and silver nanoparticles due to changes in the optical field and transition rates.
MATERIALS TODAY COMMUNICATIONS
(2023)
Article
Chemistry, Multidisciplinary
Ruike Wang, Chen Zong, Gairu Li, Junhong Wang, Tiantian Kong, Fei Li, Junmin Chang
Summary: A novel fluorescence imaging platform was developed for ultra-sensitive and rapid detection of cardiac troponin T, utilizing a high-throughput immunosensor chip and a DNA dendrimer capped with fluorescent dyes. The platform demonstrated excellent detection capabilities in serum samples, providing a new approach for early diagnosis of acute myocardial infarction.
Article
Biochemical Research Methods
Mohamad Mahani, Faeze Khakbaz, Huangxian Ju
Summary: A novel oligosensor using Si quantum dots (SiQDs) was designed and developed for the detection of miRNAs. This sensor showed high selectivity and sensitivity, and demonstrated good recovery rates in human fluid samples.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Yu Li, Jing Yuan, Shengnan Zhan, Jiaqi Hu, Yuqian Guo, Lu Ding, Xiaolin Huang, Yonghua Xiong
Summary: In this study, a DLS-based immunosensor was developed for the high-sensitivity detection of AFP, an important biomarker in the early diagnosis of primary liver cancer. By utilizing a gold in situ growth strategy and the burst release of numerous small-sized AuNPs, the sensor achieved ultrasensitive detection of AFP with a detection limit of 0.36 pg mL(-1). The proposed method was further validated with clinical serum samples and compared with a chemiluminescence immunosensor, demonstrating its potential as a novel bioanalytical platform.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Multidisciplinary
Yi Ji, Quan Zuo, Chuanshuang Chen, Yannan Liu, Yiyong Mai, Yongfeng Zhou
Summary: In this study, a multi-to-one supramolecular photocatalyst was developed by assembling multiple graphene quantum dot antennas onto a single-Pt-site porphyrin unimolecular micelle catalytic center. This photocatalyst showed high efficiency in catalyzing water splitting into hydrogen using visible light.
CHEMICAL COMMUNICATIONS
(2021)
Article
Chemistry, Multidisciplinary
Xiaotong Fan, Shuli Wang, Xiao Yang, Chenming Zhong, Guolong Chen, Changzhi Yu, Yihang Chen, Tingzhu Wu, Hao-Chung Kuo, Yue Lin, Zhong Chen
Summary: This study proposes a bicomponent perovskite nanocomposite (BPNC) for color conversion layers in micro-light-emitting-diode (micro-LED) arrays, which significantly enhances the photoluminescence intensity through the built-in Forster resonance energy transfer (FRET) from the core CsPbBr3 to the shell gamma-CsPbI3. The FRET is conducted through a pair of combined quasi-degenerate energy levels in the blue spectra region, resulting in high excitation wavelength selectivity. The BPNC exhibits the brightest single-peak red photoluminescence with near 100% quantum yield and is adaptable to a wide range of emission wavelengths when used as color downconversion layers in a blue micro-LED array.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Analytical
Yu Jin, Ke Liu, Guangqiang Li, Chengfei Li, Zhidong Xiao, Chao Yuan, Jinquan Li
Summary: This study successfully achieved high-sensitivity fluorescence detection of thiram triggered by TCEP, demonstrating the potential in developing point-of-care sensors. Additionally, a paper sensor that can be visually observed by naked eye was developed, providing new possibilities for pesticide detection. By using an in situ reduction strategy, the interaction between the target and nanoprobe was improved, leading to high sensitivity detection.
ANALYTICA CHIMICA ACTA
(2021)
Article
Chemistry, Physical
Takahisa Omata, Hiroshi Asano, Masahiro Sakai, Yoshikazu Terai, Masao Kita
Summary: The research found that the valley splitting of PbSe quantum dots can be significantly enhanced by controlling the thickness of the CdSe shell in varying inter-QD distances. When the inter-QD distance is large, Forster resonance energy transfer causes a redshift in photoluminescence emission.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2021)
Article
Chemistry, Analytical
Chunhua Wang, Yu Zhang, Wei Tang, Chao Wang, Yingkuan Han, Le Qiang, Jianwei Gao, Hong Liu, Lin Han
Summary: The developed universal biosensing platform combines the unique nanostructure and biochemistry properties of graphene oxide quantum dots with the high throughput and low cost of microfluidic chips, enabling reliable and simultaneous detection of multiple cancer biomarkers. This platform has a wide linear quantification range and ultra-low detection limits, allowing for simultaneous detection of multiple biomarkers from multiple individuals in a short time, significantly reducing detection costs and time.
ANALYTICA CHIMICA ACTA
(2021)
Article
Biochemistry & Molecular Biology
Kristyna Pavelicova, Lucie Vanickova, Yazan Haddad, Lukas Nejdl, Jan Zitka, Silvia Kociova, Filip Mravec, Tomas Vaculovic, Mirek Macka, Marketa Vaculovicova, Vojtech Adam
Summary: A new method for characterizing protein oligomerization based on FRET and capillary electrophoresis was reported, utilizing QDs and Cy3 as the donor-acceptor pair to study metallothionein dimer formation in the presence of Cd2+ ions. The successful monitoring and confirmation of MT dimer formation were achieved under aerobic conditions.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Chemistry, Analytical
Peng Qu, Cheng-Jie Li, Jin Hu, Ge Gao, Peng Lin, Wei-Wei Zhao
Summary: Organicphotoelectrochemical transistor (OPECT) biosensing is a promising approach for biomolecular sensing. This work demonstrates the direct enzymatic biocatalytic precipitation (BCP) modulation on a flower-like Bi(2)S(3) photosensitive gate, achieving high-efficiency OPECT operation with high transconductance (g (m)). The developed OPECT aptasensor shows good analysis performance for prostate-specific antigen (PSA).
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Qingqing Zhang, Yamin Fu, Ke Xiao, Cuicui Du, Xiaohua Zhang, Jinhua Chen
Summary: In this study, a dual-mode biosensor was developed for sensitive detection of CYFRA21-1, demonstrating great potential for applications in biological analysis and early disease diagnosis.
ANALYTICAL CHEMISTRY
(2021)
Review
Chemistry, Multidisciplinary
Ran Chen, Songqin Liu, Yuanjian Zhang
Summary: The development of low-cost and efficient catalytic materials is crucial for meeting energy demands and pursuing sustainable energy. Traditional electrochemical measurements lack the ability to characterize nanoscale surface features, but nanoelectrode-based studies offer a new approach. This mini-review summarizes recent progress in nanoelectrode-based studies on various nanostructured catalytic materials.
MATERIALS HORIZONS
(2023)
Article
Chemistry, Analytical
Yanfeng Fang, Zhixin Zhou, Yuhua Hou, Chenchen Wang, Xuwen Cao, Songqin Liu, Yanfei Shen, Yuanjian Zhang
Summary: We synthesized highly efficient polymeric carbon nitride (CN) films with fine-tuned electrochemiluminescence (ECL) emission from blue to green. The naked eye observable emission was significantly enhanced, and the cathodic ECL efficiency was greatly improved compared to the reference. The mechanism studies revealed crucial factors for the high ECL efficiency of CN. Based on the high ECL efficiency and different colors of ECL emission, a multiplexed ECL biosensor was constructed to detect miRNA-21 and miRNA-141 simultaneously with low detection limits.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Zhixin Zhou, Nina Lin, Yu Ouyang, Songqin Liu, Yuanjian Zhang, Itamar Willner
Summary: This article introduces the enzyme-free catalytic hairpin assembly (CHA) process for the emergence and evolution of nucleic acid networks known as constitutional dynamic networks (CDNs). The process is applied to assemble networks with varying complexities, functionalities, and spatial confinement, providing insights into the possible mechanistic pathways for the evolution of functional networks under prebiotic conditions.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Analytical
Wang Li, Mingming Zhang, Dan Han, Hong Yang, Qing Hong, Yanfeng Fang, Zhixin Zhou, Yanfei Shen, Songqin Liu, Chaofeng Huang, Haibin Zhu, Yuanjian Zhang
Summary: Photoelectrochemical (PEC) sensing allows fast, accurate, and highly sensitive detection of biologically important chemicals. However, achieving high selectivity without external biological elements remains a challenge due to the poor selectivity of PEC reactions. This study presents a strategy to address this issue by regulating charge-transfer pathways using polymeric carbon nitride (pCN)-based heterojunction photoelectrodes. By controlling the redox reactions at different semiconductor/electrolyte interfaces, each analyte showed a unique combination of photocurrent-change polarity, leading to the development of a highly selective PEC sensor for ascorbic acid in serum against common interferences.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Caixia Zhu, Hong Yang, Xuwen Cao, Qing Hong, Yuan Xu, Kaiyuan Wang, Yanfei Shen, Songqin Liu, Yuanjian Zhang
Summary: This study demonstrates a direct two-electron oxidation pathway of TMB using SDS-based micelles, which overcomes the instability issue of TMB and enables reliable glucose measurement without the need for strong acid termination.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Xinyi Hu, Xianbao Sun, Xiaoyang Liu, Hai-Dong Xu, Liang Yang, Songqin Liu, Rui Wang, Gaolin Liang
Summary: This study introduces a new molecular probe for photoacoustic imaging, which shows promising results for early diagnosis of breast cancer. The experimental results demonstrate that the molecular probe enhances the activity of urokinase-type plasminogen activator and holds great potential for application in both in vitro and in vivo settings.
ANALYTICAL CHEMISTRY
(2023)
Article
Biophysics
Qin Tao, Ning Tang, Yanjun Jiang, Bin Chen, Yuanjian Liu, Xiaohui Xiong, Songqin Liu
Summary: A color-switch electrochemiluminescence (ECL) sensing platform based on a dual-bipolar electrode (D-BPE) is developed for sensitive detection of food-borne pathogenic bacteria. The D-BPE consists of a cathode, and two anodes filled with [Ru(bpy)3]2+-TPrA and luminol-H2O2 solutions, respectively. By introducing ferrocene-labeled aptamer (Fc-aptamer) on the anodes, the ECL emission signal of [Ru(bpy)3]2+ is reduced, while luminol emits a strong ECL signal.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Engineering, Environmental
Jianyu Han, Mingxuan Zhao, Kaiqing Wu, Yixin Hong, Tianyi Huang, Xiaofei Gu, Zhi Wang, Songqin Liu, Guangcan Zhu
Summary: A bifunctional single-atom catalyst (SAC) with a Co-CN2 configuration was constructed to simultaneously degrade PFOA and reduce O2 to H2O2. The oxidative and reductive degradation were integrated within one system using immobilized Fe2O3 as a Fenton catalyst. The Co-CN2-Fe2O3 catalyst achieved a 96.1% degradation of PFOA and a 95.9% defluorination efficiency in 120 minutes.
CHEMICAL ENGINEERING JOURNAL
(2023)
Review
Chemistry, Analytical
Sisi Zhou, Yu Cao, Fanshu Shan, Puzhen Huang, Yao Yang, Songqin Liu
Summary: Plant-derived exosome like vesicles (PDEVs) are small vesicles released by various plants, which have shown multiple health benefits. Different species of PDEVs have different components and signaling pathway regulation modes. Recent advances in identifying the chemical components of single species PDEVs through omics analysis are summarized. These studies are important for understanding the health applications of PDEVs and developing new biotherapeutic approaches.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Jiajia Li, Yong Wang, Anran Liu, Songqin Liu
Summary: A highly sensitive, rapid and highly selective method for the detection of synthetic cannabinoids (SCs) in human serum was developed. Magnetic molecularly imprinted polymer (MIP) nanocomposites were prepared through self-polymerization of dopamine and template molecules. With these magnetic MIP nanoparticles, six SCs could be rapidly and effectively extracted from human blood and their concentrations accurately determined by HPLC-MS analysis. The proposed method is characterized by high sensitivity and selectivity, and has great potential for application in practical sample analysis.
Article
Chemistry, Multidisciplinary
Caixia Zhu, Zhixin Zhou, Xuejiao J. Gao, Yanhong Tao, Xuwen Cao, Yuan Xu, Yanfei Shen, Songqin Liu, Yuanjian Zhang
Summary: This article reports a nanozyme-based chemical reaction network (CRN) with feedback and feedforward functions, which can generate multiple responses to a single H2O2 stimulus. By confining this nanozymatic network to a microfluidic chip, it exhibits remarkable selectivity and linearity in perceiving H2O2 stimulus and provides an instructive platform for studying primordial life-like processes.
Article
Chemistry, Multidisciplinary
Ying Li, Yujie Chen, Kaiyuan Wang, Yufeng Zhou, Wei Wei, Yuanjian Zhang, Songqin Liu
Summary: Significant progress has been made in improving the activity of nanozymes, but there are still challenges in modulating their catalytic functions. In this study, a nanozyme (CZIF/Au) was synthesized by depositing Au nanoparticles on a CZIF. CZIF/Au displayed enhanced peroxidase-like activity under 655 nm laser irradiation and improved catalase-like activity under 808 nm laser irradiation. The different catalytic mechanisms were explained by the electron transitions triggered by the two lasers. The insights gained from this study provide a strategy for regulating the properties of nanozymes and offer prospects for their versatile use in the future.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Physical
Xiaofei Gu, Tianyi Huang, Yixin Hong, Yafeng Wu, Zhi Wang, Yuanjian Zhang, Songqin Liu, Jianyu Han
Summary: Inspired by natural photosynthesis, researchers have developed various artificial bio-coupled photocatalytic systems with promising results. However, the efficiency of these systems is hindered by the slow electron transfer kinetics. In this study, a semiartificial photosynthesis system was established using a solid electron conveyor to facilitate rapid electron transfer from the photosensitizer to the enzyme. The conformational changes induced by the framework-enzyme interaction improved the catalytic CO2 reduction rate by 190-fold compared to the traditional coenzyme system.
JOURNAL OF MATERIALS CHEMISTRY A
(2023)
Article
Chemistry, Multidisciplinary
Xiaoxiao Peng, Jin Ma, Zhixin Zhou, Hong Yang, Jingjing Chen, Ran Chen, Kaiqing Wu, Guangcheng Xi, Songqin Liu, Yanfei Shen, Yuanjian Zhang
Summary: In this study, the dissolution of polymeric carbon nitride (pCN) in polyphosphoric acid (PPA) and its fluid-phase assembly with carbon nanotubes (CNTs) into a flexible free-standing membrane were reported for the first time. The pCN/CNTs molecular composite membrane exhibited superior mechanical properties, cycling performance, and outstanding bactericidal and wound healing effects through photogenerated oxygen radicals. This opens up new possibilities for biomedical applications of pCN in molecular composite membranes beyond traditional solar fuel applications in powders.
Article
Chemistry, Multidisciplinary
Xiuxiu Li, Xiang Qin, Yafeng Wu, Kang Wang, Xinghua Xia, Songqin Liu
Summary: High-spatial resolution fluorescence imaging on a high-density gold nanoelectrode array was achieved by anchoring fluorescent molecules to limit diffusion. The sensitivity of fluorescence imaging was effectively improved by using an ionic liquid with a refractive index matching the optical system. Spatially resolved imaging of electrochemical reactions on a single nanoelectrode modified with a single Pt nanoparticle was also demonstrated.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Analytical
Yujia Ying, Huilin Li
Summary: Enzymes play a crucial role as biological catalysts in accelerating biochemical reactions in living organisms. This study proposes a convenient method for monitoring enzymatic catalytic processes using native top-down mass spectrometry. By exploring the heterogeneity of the chymotrypsin sample and using tandem mass spectrometry, the researchers were able to monitor covalent and noncovalent enzymatic complexes, substrates, and products during catalysis. The results demonstrate that this method has the potential to be a promising tool for characterizing biocatalysts.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Kang Yang, Shuaibo Shi, Jinyu Wu, Shaolong Han, Shengdi Tai, Shishen Zhang, Kun Zhang
Summary: H2O and D2O are important analogues closely related to various industries and monitoring fields. This study successfully distinguishes and detects H2O and D2O by designing a novel eu(III)-macrocycle with dual emitters, Eu-2a, and conducting fluorescence titration experiments.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Julia Kuligowski, Alvaro Perez-Rubio, Marta Moreno-Torres, Polina Soluyanova, Judith Perez-Rojas, Ivan Rienda, David Perez-Guaita, Eugenia Pareja, Ramon Trullenque-Juan, Jose Castell, Marcha Verheijen, Florian Caiment, Ramiro Jover, Guillermo Quintas
Summary: This study introduces a novel variable selection approach called cluster PLS (c-PLS) to assess the joint impact of variable groups selected based on biological characteristics on the predictive performance of a multivariate model. The usefulness of c-PLS is shown using miRNomic and metabolomic datasets obtained from the analysis of liver tissue biopsies.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Meixue Lai, Lijie Zhong, Siyi Liu, Yitian Tang, Tingting Han, Huali Deng, Yu Bao, Yingming Ma, Wei Wang, Li Niu, Shiyu Gan
Summary: This study presents a method for constructing wearable sweat electrolyte sensors using carbon fiber-based solid-contact ion-selective electrodes (SC-ISEs). By using carbon fibers extracted from commercial cloth as electrode material, the cost and reproducibility issues of flexible SC-ISEs were addressed. The results showed that the carbon fiber-based SC-ISEs exhibited reversible voltammetric and stable impedance performances, and had high reproducibility of standard potentials between normal and bending states.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Yang, Ying Liu, Min Deng, Peipei Wang, Dan Cheng, Songjiao Li, Longwei He
Summary: A near-infrared fluorescent probe has been developed to accurately measure the levels of peroxynitrite (ONOO-) in the endoplasmic reticulum (ER) in acute lung injury (ALI). The probe demonstrated rapid response, high selectivity, good sensitivity, and enhanced fluorescence intensity in response to ONOO-. It was successfully used to detect changes in ONOO- levels and showed significant increases in an ALI cell model and an ALI mouse model.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yanping Wang, Yuemei Chen, Kejun Li, Jinrong Zhou, Xin Yuan, Mei Zhang, Ke Huang
Summary: In this work, a portable analytical system based on point discharge chemical vapor generation atomic emission spectrometry (PD-CVG-AES) coupling with gold filament enrichment was designed. The highly sensitive analysis of Hg2+ indirectly realized the detection of ascorbic acid (AA). The measurement is based on the fact that Ag+ can decrease the concentration of Hg2+ by forming Ag-Hg amalgam in the presence of the reductant SnCl2, while AA can pre-reduce Ag+ to Ag0, leading to the generation of silver nanoparticles (Ag NPs). The developed novel analytical strategy broadens the application of microplasma-based AES and offers a higher level of sensitivity compared to current AA detection techniques.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yundi Huang, Bo Song, Kaiwen Chen, Deshu Kong, Jingli Yuan
Summary: This study developed two lysosome-targetable background-free TGL probes for efficient and accurate detection of 1O2, which can be used for monitoring endogenous 1O2 concentrations in lysosomes and discriminating variability induced by different photosensitizers. Furthermore, a smart luminescent sensor film was successfully prepared for on-site 1O2 production detection during PDT processes, offering a promising clinical monitoring tool for skin diseases.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Wei Lang, Jia-Mei Qin, Qian-Yong Cao
Summary: A novel polymer-based probe P1 was successfully synthesized for fluorescently ratiometric sensing of H2S with high selectivity and sensitivity. A smartphone sensing platform was constructed to conduct visual quantitative detection of H2S. P1 can be employed in evaluating the level fluctuations of H2S in living cells, testing water samples/wine samples, and monitoring food freshness.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yuanyuan Qin, Shuda Liu, Shuyun Meng, Dong Liu, Tianyan You
Summary: The study developed a split aptamer-based sandwich-type ratiometric biosensor for the detection of 17 beta-estradiol (E2) using photoelectrochemical and electrochemical assays. The biosensor utilized split aptamer fragments to recognize E2 and trigger a hybridization chain reaction, resulting in the production of double-stranded DNA labeled with CdTe quantum dots. This DNA complex was able to sensitize CdTe quantum dots and generate response signals for E2 detection. The developed biosensor demonstrated high sensitivity and accuracy with two linear ranges and low detection limits.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Siriwan Teepoo, Jongjit Jantra, Khaunnapa Panapong, David Taiwo Ajayi
Summary: A novel immunochromatographic assay based on hyperbranched Au plasmonic blackbodies with a smartphone readout was developed for rapid and sensitive detection of leucomalachite green residues in fish and shrimp products.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Andrea L. Larraga-Urdaz, Borja Moreira-Alvarez, Jorge Ruiz Encinar, Jose M. Costa-Fernandez, Maria Luisa Fernandez-Sanchez
Summary: A major challenge in the 21st century is the development of point-of-care diagnostic tools. In this study, a highly sensitive and simple bioassay using AuNPs and MNAzymes was developed for rapid detection and quantification of miRNA-4739. The proposed strategy shows potential for breast cancer diagnosis.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Xiaohan Zhao, Anyu Wang, Lingzi Zhai, Jiuhe Gao, Sizhe Lyu, Yingshan Jiang, Tian Zhong, Ying Xiao, Xi Yu
Summary: A novel method using polystyrene-coated magnetic nanoparticles for extracting monohydroxy polycyclic aromatic hydrocarbons from urine samples was investigated. The proposed method is simple, sensitive, and efficient, with desirable sensitivity for analyzing low-abundance metabolites in large volumes of complex urine samples.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Quan, Yuqing Zeng, Wenke Zhang, Fengfeng Li, Mengjiao Li, Zhihe Qing, Linlin Wu
Summary: In this study, a visual and reusable biosensor was developed for detecting substrates that are closely associated with human physiological health. The immobilized oxidase showed higher stability and sensitivity under harsh conditions, enabling reliable detection of substrates in complex fluids.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Dongjuan Wang, Xiuqian Ding, Jinling Xie, Juan Wang, Guanhao Li, Xin Zhou
Summary: In this study, a three-in-one sensor was developed for real-time detection of biogenic amines (BAs) with high sensitivity and selectivity. The sensor showed multimodal responses and could be used to fabricate portable devices for on-site non-destructive assessment of food spoilage indicators.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Jinting Meng, Zihao Xu, Shasha Zheng, Hongqun Yang, Tianfu Wang, Hong Wang, Yingwei Zhang
Summary: This study demonstrates the development of a cascade signal amplification system using a multi-pedal DNA walker and strand displacement reactions for the electrochemical detection of miRNA-155. The biosensor exhibited high sensitivity, selectivity, and the potential for clinical applications.
ANALYTICA CHIMICA ACTA
(2024)
