Correction
Chemistry, Multidisciplinary
Celia Arib, Nadia Bouchemal, Maria Barile, Didier Paleni, Nadia Djaker, Nathalie Dupont, Jolanda Spadavecchia
Summary: This study presents a novel design of gold nanoparticles by using flavin-adenine-dinucleotide as a coupling reagent, and evaluates their physico-chemical properties, as well as discusses their potential applications in nanomedicine.
NANOSCALE ADVANCES
(2023)
Article
Biochemical Research Methods
Amani A. Gillette, Rebecca A. DeStefanis, Stephanie L. Pritzl, Dustin A. Deming, Melissa C. Skala
Summary: This study investigates the effects of Bcl-2 family protein inhibitors on cellular metabolism and finds that the optical redox ratio (ORR) is sensitive to changes in mitochondrial function and cell senescence, which can occur independently of cell viability. The metabolic changes caused by ABT-263 treatment can be mitigated by combination with mTORC1/2 inhibitors.
JOURNAL OF BIOMEDICAL OPTICS
(2022)
Article
Instruments & Instrumentation
Virginia Merk, Eugen Speiser, Wolfgang Werncke, Norbert Esser, Janina Kneipp
Summary: The ultraviolet resonance Raman spectra of NAD+ and FAD in aqueous solution at physiological concentration were compared in order to distinguish them from their building block, adenine, in potential co-occurrence in biological materials. The measurement of spectra at different pH values showed characteristic changes mainly due to deprotonation of flavin and nicotinamide moieties, and protonation of adenine.
APPLIED SPECTROSCOPY
(2021)
Article
Biotechnology & Applied Microbiology
Xinxin Liu, Hong Lu, Qiansheng Li, Ze Fu, Feng Tan, Xiaolei Wang, Jiti Zhou
Summary: In this study, novel core-shell magnetic molecularly imprinted polymers (MMIPs) were successfully prepared for flavins. The results showed that MMIPs exhibited good adsorption capacity and catalytic performance for flavins, which can be applied to accelerate anaerobic biotransformation of refractory pollutants.
JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Shima Mehrvar, Soudeh Mostaghimi, Farnaz H. Foomani, Betsy Abroe, Janis T. Eells, Sandeep Gopalakrishnan, Mahsa Ranji
Summary: The study quantitatively evaluated the effect of far-red light exposure on mitochondrial bioenergetics of diabetic wounds and found that far-red light exposure improved mitochondrial function and accelerated wound healing, possibly through increasing mitochondrial RR and reducing oxidative stress.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2021)
Article
Gastroenterology & Hepatology
Ki-Hoon Park, Monika Gooz, Zhi-Wei Ye, Jie Zhang, Gyda C. Beeson, Don C. Rockey, Seok-Hyung Kim
Summary: This study reveals that ETFA haploinsufficiency leads to hyperlipidemia, hypercholesterolemia, hepatic steatosis, and injury in adult zebrafish. Reduction in levels of FAD and glutathione, as well as an increase in reactive oxygen species, was observed in mutant livers. Riboflavin supplementation counteracted these effects, highlighting the role of FAD depletion in hepatic steatosis and oxidative stress-mediated liver injury.
HEPATOLOGY COMMUNICATIONS
(2021)
Review
Nutrition & Dietetics
Tze Yan Lee, Nuratiqah Farah, Voon Kin Chin, Chee Woei Lim, Pei Pei Chong, Rusliza Basir, Wai Feng Lim, Yan Shan Loo
Summary: Riboflavin is an essential coenzyme that plays a significant role in energy metabolism and the metabolism of various nutrients. It possesses antioxidant properties and has been explored for its potential use in pharmaceutical and clinical contexts, such as preventing oxidative stress, treating colorectal cancer, and improving diabetes mellitus comorbidities.
NUTRITION RESEARCH
(2023)
Article
Chemistry, Analytical
E. Guillen, J. Agrisuelas, J. J. Garcia-Jareno, F. Vicente
Summary: Thin films of PEDOT were electrochemically deposited on gold electrodes in aqueous media, and the effects of various ions during the charge/discharge process were investigated. The study found that the relative participation of anions and cations changed at different potentials, with a secondary electrochemical reaction appearing at a specific potential. Additionally, the viscoelastic properties of the film changed mainly at more negative potentials due to the exchange of highly hydrated Li cations.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Sunghark Kwon
Summary: This study analyzed the structure of FADS from the human pathogen Streptococcus pneumoniae and predicted possible substrate-binding modes, providing a structural basis for understanding the catalytic mechanism of SpFADS and developing novel inhibitors.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemical Research Methods
Annemarie Jacob, He N. Xu, Andrea L. Stout, Lin Z. Li
Summary: This study compared the ability of whole-cell and subcellular ORI indices and N:C ratio to differentiate between breast cancer subtypes and between mitotic and nonmitotic cells. The results showed that subcellular ORI analysis better distinguishes breast cancer subtypes with varying aggressiveness than N:C area ratio.
JOURNAL OF BIOMEDICAL OPTICS
(2022)
Article
Biochemical Research Methods
Stella Yang, Joyce Farrell, Shenglin Ye, Iram Ahmad, Tulio A. Valdez
Summary: This study aims to develop an imaging system to enhance the visibility of cholesteatoma tissue during surgery. The researchers found that cholesteatoma tissue fluoresced under 405 and 450 nm illumination, while mucosa tissue did not. A prototype fluorescence imaging system was built to accurately measure cholesteatoma tissue autofluorescence.
JOURNAL OF BIOMEDICAL OPTICS
(2023)
Article
Chemistry, Physical
Ebrar Dokur, Selen Uruc, Ozge Gorduk, Yucel Sahin
Summary: This study reports a new electrochemical sensor platform prepared using tetraoctylammonium ions (TOA(+)) for efficient determination of reduced beta-nicotinamide adenine dinucleotide (NADH). The sensor was characterized using various techniques and showed excellent analytical performance, including low detection limits, high sensitivity, stability, and specificity. The proposed TOA(+)/PGE-based sensor displayed good performance in detecting NADH levels in human blood samples, even in the presence of interfering species.
Review
Biochemistry & Molecular Biology
Ferdinando Palmieri, Magnus Monne, Giuseppe Fiermonte, Luigi Palmieri
Summary: Multiple mitochondrial matrix enzymes require cofactors for their action, which are transported by mitochondrial carriers. Mutations in mitochondrial cofactor carrier genes can compromise enzymatic activity and metabolic pathways.
Article
Biochemical Research Methods
Christian Freymueller, Sviatlana Kalinina, Angelika Rueck, Ronald Sroka, Adrian Ruehm
Summary: Two-photon fluorescence lifetime imaging is a versatile laboratory technique widely used in biophotonics, with growing importance in medical diagnostics. Researchers have developed reliable NADH- and FAD-mimicking optical phantoms for this technique by designing suitable reference samples, providing reproducibility and stability for this relevant diagnostic method.
JOURNAL OF BIOPHOTONICS
(2021)
Article
Biochemical Research Methods
Rebecca Schmitz, Kelsey Tweed, Christine Walsh, Alex J. Walsh, Melissa C. Skala
Summary: The study investigated the effect of extracellular pH on the fluorescence lifetimes of FAD, FMN, and NAD(P)H. Results showed that FAD and NAD(P)H mean lifetimes increased and decreased, respectively, with increasing pH, with differences observed between the two cell lines.
JOURNAL OF BIOMEDICAL OPTICS
(2021)
Article
Electrochemistry
Tzu-Hsuan Wang, Chia-Yu Lin, Yu-Cheng Huang, Chia-Ying Li
Summary: In this work, a facile and scalable electrosynthetic approach was developed to prepare core-shell-structured polyaniline|gold nanoparticles nanofiber (nanoPANI|Au) as an efficient electrocatalyst for electrochemical CO2 reduction (e-CO2RR). Under optimal conditions, the prepared nanoPANI|Au exhibited high turnover frequency of 0.40 s-1 and CO-mass activity of 5.67 A g-1 with satisfactory selectivity (Faradaic efficiency: 70.0 +/- 2.1%) for CO generation in 0.1M NaHCO3 at a moderate over-potential of 0.59 V. This work opens a new avenue for the preparation of core-shell-structured conducting polymer|metal nanoparticles as electrocatalysts for e-CO2RR.
ELECTROCHIMICA ACTA
(2023)
Article
Cardiac & Cardiovascular Systems
Yu-Tsung Shih, Shu-Yi Wei, Jin-Hua Chen, Wei-Li Wang, Hsin-Yi Wu, Mei-Cun Wang, Chia-Yu Lin, Pei-Lin Lee, Chih-Yuan Lin, Hung-Che Chiang, Yu-Ju Chen, Shu Chien, Jeng-Jiann Chiu
Summary: This study reveals the regulation of vascular endothelial phosphoproteins induced by disturbed flow and their contribution to atherogenesis. The phosphorylation of vinculin at serine 721 induced by disturbed flow promotes endothelial permeability and atherosclerosis. The level of endothelial VCLS721p is a clinicopathological biomarker for atherosclerosis progression.
EUROPEAN HEART JOURNAL
(2023)
Article
Polymer Science
Ping-Jui Yu, Yan-Cheng Lin, Chia-Yu Lin, Wen-Chang Chen
Summary: Diverse approaches have been presented to synthesize intrinsically stretchable conjugated polymers, but compromise in charge carrier mobility is often observed. This study engineered polythiophenes with flexible or rigid backbones and different side chains to improve their mechanical tolerance and amorphous content. The best mobility-stretchability properties were observed in polythiophene with a quaterthiophene backbone and thienyl-ester-substituted side chains. The jointed design of biaxial extension and ester functional groups proved to be efficacious in improving the mobility-stretchability properties of polythiophenes.
Article
Nanoscience & Nanotechnology
Gaurav Kumar Silori, Subashchandrabose Thoka, Kuo-Chuan Ho
Summary: The applicability of nanofillers in gel polymer electrolyte (GPE)-based devices has significantly increased in the past decade. However, the development of their applicability in GPE-based electrochromic devices (ECDs) has been limited due to challenges such as optical inhomogeneity, transmittance drop, and poor electrolyte fabrication methodologies. In this study, a reinforced polymer electrolyte tailored through PVDF-HFP, BMIMBF4, and various types of mesoporous SiO2 nanofillers was demonstrated to address these issues.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Chung -Wei Kung, Ken-ichi Otake, Riki J. Drout, Subhadip Goswami, Omar K. Farha, Joseph T. Hupp
Summary: Starting with ferrocyanide ions in acidic aqueous solution, cyano-ferrate(II) species are post-synthetically grafted to the nodes of a mesoporous zirconium-based MOF, NU-1000. The grafting occurs by substitution of cyanide ligands by node-based hydroxo and oxo ligands rather than by substitution of node aqua ligands by cyanide ligands as bridges between Fe(II) and Zr(IV). The installed moieties yield a broad absorption band that is tentatively ascribed to iron-to-zirconium charge transfer. Consistent with Fe(III/II) redox activity, a modest fraction of the installed iron complexes are directly electrochemically addressable.
Article
Polymer Science
Chih-Yuan Sung, Chia-Yu Lin, Chu-Chen Chueh, Yan-Cheng Lin, Wen-Chang Chen
Summary: Until now, the study of the mobility-stretchability of semiconducting polymers has received extensive attention, but little focus has been placed on their morphology and field-effect transistor characteristics under compressive strains, which are equally important in wearable electronic applications. This research applies a contact film transfer method to evaluate the mobility-compressibility properties of conjugated polymers. Various isoindigo-bithiophene conjugated polymers with different side chains are investigated, and it is found that P(SiO-Si) outperforms other symmetric polymers in dissipating strain and enhancing mechanical durability. The contact film transfer technique is also demonstrated to be applicable for studying the compressibility of different semiconducting polymers. These results provide a comprehensive understanding of the mobility-compressibility properties of semiconducting polymers under tensile and compressive strains.
MACROMOLECULAR RAPID COMMUNICATIONS
(2023)
Article
Polymer Science
Megumi Matsuda, Chia -Yu Lin, Kazushi Enomoto, Yan-Cheng Lin, Wen-Chang Chen, Tomoya Higashihara
Summary: In this study, the development of stretchable semiconducting polymers through statistical terpolymerization with conjugation break spacers (CBSs) was investigated. The inclusion of thioether units into naphthalenediimide (NDI)-based semiconducting polymers was found to significantly affect their semiconductivity and stretchability, compared to alkyl- and ether-based CBSs.
Article
Multidisciplinary Sciences
Fu-Xiang Rikudo Chen, Chia-Yu Lin, Hui-Ying Siao, Cheng-Yuan Jian, Yong-Cheng Yang, Chun-Liang Lin
Summary: In this study, a deep learning-based atomic defect detection framework (DL-ADD) is proposed to efficiently detect atomic defects in molybdenum disulfide (MoS2) and generalize the model for defect detection in other TMD materials.
Article
Health Care Sciences & Services
Yi-Huei Chang, Szu-Ying Pan, Chia-Yu Lin, Chi-Ping Huang, Chi-Jung Chung, Yung-Hsiang Chen, Wen-Chi Chen
Summary: Prostate abscess (PA) is a potentially life-threatening condition that requires prompt treatment. However, the declining incidence of PA in developing countries and high-risk patients can hinder early diagnosis. This study aimed to review the etiology, pathophysiology, diagnosis, and treatment options for PA, as well as analyze the characteristics and clinical course of patients. The findings can guide the development of a personalized treatment strategy for patients with PA.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Health Care Sciences & Services
Chia-Hui Chen, Chia-Yu Lin, Chiao-Ling Chen, Kuan-Ting Chen, Cho Lee, Ya-Hsin Yu, Chiao-Yu Shih
Summary: This study investigated the effectiveness of regular physical exercise-based swallowing intervention for reducing coughing and choking in older adults with dementia. The findings suggest that such intervention can effectively alleviate coughing and choking problems and its effectiveness is long-lasting. However, individuals with more advanced age and higher dementia levels may experience shorter-term effectiveness from the intervention.
Article
Nanoscience & Nanotechnology
Jia-Yun Tu, Cheng-Hui Shen, De-Hao Tsai, Chung-Wei Kung
Summary: Nickel is efficiently incorporated into a highly porous cerium(IV)-based metal-organic framework (MOF) using either conventional impregnation or self-limiting post-synthetic modification, and then carbonized to prepare nanosized MOF-derived ceria-supported nickel. The catalytic activity, crystallinity, porosity, nanostructural morphology, and surface properties of the MOF and MOF-derived materials are characterized. The use of post-synthetic modification to install the catalytically active species in MOFs effectively retards the agglomeration of nickel during the long-term bi-reforming of methane (BRM), suggesting its benefit in designing more resistive MOF-derived catalysts.
ACS APPLIED NANO MATERIALS
(2023)
Article
Nanoscience & Nanotechnology
Yu-Na Chang, Cheng-Hui Shen, Chi-Wei Huang, Meng-Dian Tsai, Chung-Wei Kung
Summary: In this study, a water-stable and nanoporous zirconium-based MOF, UiO-66, with tunable missing-linker defects is synthesized and applied as a signal amplifier to enhance the electrochemical sensing performance for dopamine detection.
ACS APPLIED NANO MATERIALS
(2023)
Article
Materials Science, Multidisciplinary
Cheng-Hui Shen, Yu-Na Chang, You-Liang Chen, Chung-Wei Kung
Summary: A highly porous and chemically stable metal-organic framework (MOF) with enriched sulfonate groups, SO3-MOF-808, is synthesized and proposed as a porous alternative to Nafion for modulating the selectivity of electrochemical reactions. The use of SO3-MOF-808 thin film as an electrode coating significantly improves the current signal for dopamine oxidation and the selectivity against interfering compounds.
ACS MATERIALS LETTERS
(2023)
Article
Electrochemistry
Cheng-Hui Shen, Chung-Wei Kung
Summary: This article highlights the concept of utilizing stable but electrochemically inactive MOFs to modulate the microenvironment and improve the reaction rates and selectivity of electrocatalytic reactions.
Article
Chemistry, Physical
Meng-Dian Tsai, You-Liang Chen, Jhe-Wei Chang, Shang-Cheng Yang, Chung-Wei Kung
Summary: In this study, a sulfonate-functionalized two-dimensional zirconium-based metal-organic framework (MOF) was used as a dispersant to spatially separate polyaniline (PANI) chains in composites, resulting in significantly improved specific capacitance compared to traditional dispersants.
ACS APPLIED ENERGY MATERIALS
(2023)
Article
Chemistry, Analytical
Yujia Ying, Huilin Li
Summary: Enzymes play a crucial role as biological catalysts in accelerating biochemical reactions in living organisms. This study proposes a convenient method for monitoring enzymatic catalytic processes using native top-down mass spectrometry. By exploring the heterogeneity of the chymotrypsin sample and using tandem mass spectrometry, the researchers were able to monitor covalent and noncovalent enzymatic complexes, substrates, and products during catalysis. The results demonstrate that this method has the potential to be a promising tool for characterizing biocatalysts.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Kang Yang, Shuaibo Shi, Jinyu Wu, Shaolong Han, Shengdi Tai, Shishen Zhang, Kun Zhang
Summary: H2O and D2O are important analogues closely related to various industries and monitoring fields. This study successfully distinguishes and detects H2O and D2O by designing a novel eu(III)-macrocycle with dual emitters, Eu-2a, and conducting fluorescence titration experiments.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Julia Kuligowski, Alvaro Perez-Rubio, Marta Moreno-Torres, Polina Soluyanova, Judith Perez-Rojas, Ivan Rienda, David Perez-Guaita, Eugenia Pareja, Ramon Trullenque-Juan, Jose Castell, Marcha Verheijen, Florian Caiment, Ramiro Jover, Guillermo Quintas
Summary: This study introduces a novel variable selection approach called cluster PLS (c-PLS) to assess the joint impact of variable groups selected based on biological characteristics on the predictive performance of a multivariate model. The usefulness of c-PLS is shown using miRNomic and metabolomic datasets obtained from the analysis of liver tissue biopsies.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Meixue Lai, Lijie Zhong, Siyi Liu, Yitian Tang, Tingting Han, Huali Deng, Yu Bao, Yingming Ma, Wei Wang, Li Niu, Shiyu Gan
Summary: This study presents a method for constructing wearable sweat electrolyte sensors using carbon fiber-based solid-contact ion-selective electrodes (SC-ISEs). By using carbon fibers extracted from commercial cloth as electrode material, the cost and reproducibility issues of flexible SC-ISEs were addressed. The results showed that the carbon fiber-based SC-ISEs exhibited reversible voltammetric and stable impedance performances, and had high reproducibility of standard potentials between normal and bending states.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Yang, Ying Liu, Min Deng, Peipei Wang, Dan Cheng, Songjiao Li, Longwei He
Summary: A near-infrared fluorescent probe has been developed to accurately measure the levels of peroxynitrite (ONOO-) in the endoplasmic reticulum (ER) in acute lung injury (ALI). The probe demonstrated rapid response, high selectivity, good sensitivity, and enhanced fluorescence intensity in response to ONOO-. It was successfully used to detect changes in ONOO- levels and showed significant increases in an ALI cell model and an ALI mouse model.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yanping Wang, Yuemei Chen, Kejun Li, Jinrong Zhou, Xin Yuan, Mei Zhang, Ke Huang
Summary: In this work, a portable analytical system based on point discharge chemical vapor generation atomic emission spectrometry (PD-CVG-AES) coupling with gold filament enrichment was designed. The highly sensitive analysis of Hg2+ indirectly realized the detection of ascorbic acid (AA). The measurement is based on the fact that Ag+ can decrease the concentration of Hg2+ by forming Ag-Hg amalgam in the presence of the reductant SnCl2, while AA can pre-reduce Ag+ to Ag0, leading to the generation of silver nanoparticles (Ag NPs). The developed novel analytical strategy broadens the application of microplasma-based AES and offers a higher level of sensitivity compared to current AA detection techniques.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yundi Huang, Bo Song, Kaiwen Chen, Deshu Kong, Jingli Yuan
Summary: This study developed two lysosome-targetable background-free TGL probes for efficient and accurate detection of 1O2, which can be used for monitoring endogenous 1O2 concentrations in lysosomes and discriminating variability induced by different photosensitizers. Furthermore, a smart luminescent sensor film was successfully prepared for on-site 1O2 production detection during PDT processes, offering a promising clinical monitoring tool for skin diseases.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Wei Lang, Jia-Mei Qin, Qian-Yong Cao
Summary: A novel polymer-based probe P1 was successfully synthesized for fluorescently ratiometric sensing of H2S with high selectivity and sensitivity. A smartphone sensing platform was constructed to conduct visual quantitative detection of H2S. P1 can be employed in evaluating the level fluctuations of H2S in living cells, testing water samples/wine samples, and monitoring food freshness.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yuanyuan Qin, Shuda Liu, Shuyun Meng, Dong Liu, Tianyan You
Summary: The study developed a split aptamer-based sandwich-type ratiometric biosensor for the detection of 17 beta-estradiol (E2) using photoelectrochemical and electrochemical assays. The biosensor utilized split aptamer fragments to recognize E2 and trigger a hybridization chain reaction, resulting in the production of double-stranded DNA labeled with CdTe quantum dots. This DNA complex was able to sensitize CdTe quantum dots and generate response signals for E2 detection. The developed biosensor demonstrated high sensitivity and accuracy with two linear ranges and low detection limits.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Siriwan Teepoo, Jongjit Jantra, Khaunnapa Panapong, David Taiwo Ajayi
Summary: A novel immunochromatographic assay based on hyperbranched Au plasmonic blackbodies with a smartphone readout was developed for rapid and sensitive detection of leucomalachite green residues in fish and shrimp products.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Andrea L. Larraga-Urdaz, Borja Moreira-Alvarez, Jorge Ruiz Encinar, Jose M. Costa-Fernandez, Maria Luisa Fernandez-Sanchez
Summary: A major challenge in the 21st century is the development of point-of-care diagnostic tools. In this study, a highly sensitive and simple bioassay using AuNPs and MNAzymes was developed for rapid detection and quantification of miRNA-4739. The proposed strategy shows potential for breast cancer diagnosis.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Xiaohan Zhao, Anyu Wang, Lingzi Zhai, Jiuhe Gao, Sizhe Lyu, Yingshan Jiang, Tian Zhong, Ying Xiao, Xi Yu
Summary: A novel method using polystyrene-coated magnetic nanoparticles for extracting monohydroxy polycyclic aromatic hydrocarbons from urine samples was investigated. The proposed method is simple, sensitive, and efficient, with desirable sensitivity for analyzing low-abundance metabolites in large volumes of complex urine samples.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Quan, Yuqing Zeng, Wenke Zhang, Fengfeng Li, Mengjiao Li, Zhihe Qing, Linlin Wu
Summary: In this study, a visual and reusable biosensor was developed for detecting substrates that are closely associated with human physiological health. The immobilized oxidase showed higher stability and sensitivity under harsh conditions, enabling reliable detection of substrates in complex fluids.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Dongjuan Wang, Xiuqian Ding, Jinling Xie, Juan Wang, Guanhao Li, Xin Zhou
Summary: In this study, a three-in-one sensor was developed for real-time detection of biogenic amines (BAs) with high sensitivity and selectivity. The sensor showed multimodal responses and could be used to fabricate portable devices for on-site non-destructive assessment of food spoilage indicators.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Jinting Meng, Zihao Xu, Shasha Zheng, Hongqun Yang, Tianfu Wang, Hong Wang, Yingwei Zhang
Summary: This study demonstrates the development of a cascade signal amplification system using a multi-pedal DNA walker and strand displacement reactions for the electrochemical detection of miRNA-155. The biosensor exhibited high sensitivity, selectivity, and the potential for clinical applications.
ANALYTICA CHIMICA ACTA
(2024)