Article
Chemistry, Analytical
Adam Morris, Nuria Serrano, Jose Manuel Diaz-Cruz, Avi Bendavid, Miao Chen, Mikko Vepsalainen
Summary: The study demonstrated the superior performance of a vibrating boron-doped diamond electrode in combination with the ASV method for the analysis of ultralow concentrations of Cd(II) in water, without the need for surface modification or regular replacement of the electrode, making it suitable for on-site and online heavy metal analysis.
ANALYTICA CHIMICA ACTA
(2021)
Article
Chemistry, Analytical
Reyhan Dincer, Sukriye Ulubay Karabiberoglu, Zekerya Dursun
Summary: This study proposes a dependable approach for the selective and sensitive identification of zinc, cadmium and lead in different sample matrices using an over-oxidized poly(xylenol blue) film glassy carbon electrode coated with bismuth (Bi/PXBov.ox/GCE). The best conditions for determining these elements were found to be a 0.1 mol L-1 acetate buffer solution as supporting electrolyte (pH 4.5), -1.5 V accumulation potential, and 180 s accumulation duration. Under these conditions, the detection limits of Zn(II), Cd(II) and Pb(II) were 3.20 μg L-1, 0.21 μg L-1 and 1.98 μg L-1, respectively. Moreover, this novel, cheap and easy-to-prepare Bi/PXBov.ox/GCE was successfully used for the analysis of Zn(II), Cd(II) and Pb(II) in lipstick samples, with consistent results compared to inductively coupled plasma mass spectrometry.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Gul Sirin Ustabasi, Ismail Yilmaz, Mustafa Ozcan, Ebru Cetinkaya
Summary: Pencil graphite electrode modified with MWCNT and Bi3+ showed improved sensitivity and reduced charge transfer resistance in the simultaneous analysis of Pb2+, Cd2+, and Zn2+. This modification method offers effective electroanalytical performance with low time consumption and cost.
Article
Biochemistry & Molecular Biology
Siyamthanda Hope Mnyipika, Tshimangadzo Saddam Munonde, Philiswa Nosizo Nomngongo
Summary: This paper describes the successful fabrication of an electrochemical sensor by electrodeposition of MnO2 nanoparticles and RGO nanosheets, which significantly improved the detection of Zn(II), Cd(II) and Cu(II) ions in surface water. The modified sensor electrode exhibited high sensitivity, reproducibility, and stability for simultaneous determination of the three metal ions. The results demonstrate the potential of MnO2@RGO nanocomposite for early detection of heavy metals in water samples with enhanced sensitivity.
Article
Chemistry, Analytical
Martijn Eikelboom, Yaxuan Wang, Gemma Portlock, Arthur Gourain, Joseph Gardner, Jay Bullen, Paul Lewtas, Matthieu Carriere, Alexandra Alvarez, Arun Kumar, Shane O'Prey, Tamas Tolgyes, Dario Omanovic, Subhamoy Bhowmick, Dominik Weiss, Pascal Salaun
Summary: The voltammetric determination of total inorganic arsenic in near-neutral pH conditions using a new commercially available 25 μm diameter gold microwire was presented. The method has better analytical parameters than previous methods and is easier to implement, enabling cheaper groundwater surveying campaigns with in-the-field analysis for quick data reporting, even in remote communities.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Analytical
Shi-Hua Chen, Zong-Yin Song, Xiang-Yu Xiao, Hong-Qi Huang, Yuan-Fan Yang, Pei-Hua Li, Meng Yang, Xing-Jiu Huang
Summary: Vacancy and doping engineering were used to improve the electrocatalytic ability of nanomaterials for detecting heavy metal ions. The P-doped material showed enhanced sensitivity and selectivity towards As(III), and the vacancies provided abundant electrons to form active centers.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Artur Huseinov, Abdul Hoque, Kyle A. Ruble, Brandon J. Dee, Noe T. Alvarez
Summary: This study presents a reagentless sample preparation method for the detection of particulate Pb contaminants in tap water using membrane electrolysis. The membrane electrolysis allows for the in-situ generation of nitric acid, which, when combined with anodic stripping voltammetry, provides a powerful and reagent-free detection of Pb2+. The setup configuration enables semi-autonomous operation and requires minimal attention, making it more suitable for continuous measurements of particulate contaminants in tap water.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Hossein Dastangoo, Mir Reza Majidi, Maryam Kalantar Hormozi
Summary: In this study, palladized aluminum was used as a new type of solid electrode for the determination of copper using the differential pulse anodic stripping voltammetry (DPASV) technique. The preparation of the electrode involved electroless deposition of metallic palladium on the aluminum surface, resulting in good sensitivity and selectivity. Various experimental variables were optimized, and under the optimal conditions, a linear calibration graph was achieved for copper concentration determination. The proposed method showed no interference and was successfully applied for determining copper content in nutritional supplement tablets.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Tianyi Zhang, Peng Zhou, Terrence Simon, Tianhong Cui
Summary: This study introduces a vibrating air bubble as a stirrer to enhance mass transfer in electrochemical sensing, leading to a twelve-fold increase in mass transfer coefficient compared to the static case. The enhanced sensing performance is quantified experimentally with an integrated electrochemical metal ion sensor, showing potential for various electrochemical sensing applications limited by slow molecular diffusion.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Analytical
Hui Li, Jie Zhao, Shifan Zhao, Guofeng Cui
Summary: A novel three-electrode sensor was developed for simultaneous detection of Pb(II), Cd(II), and Zn(II) by depositing a bismuth film on a screen-printed gold working electrode. The sensor showed a wide linear range, low detection limits, good anti-interference ability, and stability. Such sensors are expected to be useful for portable heavy metal detection applications.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
Elena Dorozhko, Anna S. Gashevskay, Elena Korotkova, Jiri Barek, Vlastimil Vyskocil, Sergei A. Eremin, Evgeny Galunin, Muhammad Saqib
Summary: This study synthesized a hapten-protein conjugate with copper nanoparticles (Hap-Car-BSA@CuNPs) for the determination of carbaryl, and successfully developed a novel method for monitoring carbaryl residues in flour samples using an electrochemical immunosensor. The detection range was 0.8-32.3 μg/kg with a limit of detection of 0.08 μg/kg.
Review
Chemistry, Multidisciplinary
Enyioma C. Okpara, Omolola E. Fayemi, Olanrewaju B. Wojuola, Damian C. Onwudiwe, Eno E. Ebenso
Summary: The safety of global water resources is threatened by various human activities and climate change, particularly heavy metal contamination in African water supply. There is a need for a global campaign to address the impact of heavy metals on drinking water and to develop fast, affordable, sensitive, selective, and stable detection methods.
Article
Chemistry, Analytical
Yifei Zhang, Danlei Li, Richard G. Compton
Summary: We have developed a new and sensitive stripping voltammetric method for the detection of As(III) in aqueous solution using gold macroelectrode or gold nanoparticle-modified glassy carbon electrode (GCE). The method is based on underpotential deposition (UPD) of As ad-atoms and provides linear responses within the range of 0.01 μM to 0.1 μM or 0.005 μM to 0.1 μM for gold macroelectrodes and gold nanoparticle-modified electrodes, respectively. The method shows practical value with clear and discernable signals even at low concentrations of As(III), meeting the WHO limit for drinking water.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Ali Nourbakhsh, Mostafa Rahimnejad, Maryam Asghary, Habibollah Younesi
Summary: This study developed a sensitive platform based on silver nanoparticles/graphene nanoplates modified graphite electrode for the simultaneous and selective determination of heavy metal ions in tap water. The experimental results showed that the electrochemical sensor exhibited high practical applicability, reproducibility, and stability in detecting heavy metal ions.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Guo Zhao, Thien-Toan Tran, Sidharth Modha, Mohammed Sedki, Nosang V. Myung, David Jassby, Ashok Mulchandani
Summary: This study presents multiplexed anodic stripping voltammetry detection of heavy metal ions using a homemade electrochemical cell with a 3D-printed flow cell. The sensor platform showed high selectivity and accuracy, with a potential applicability in complex matrices, achieving a 95-101% recovery rate in simulated river water.
FRONTIERS IN CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Joao M. Vindeirinho, Helena M. V. M. Soares, Eduardo Soares
Summary: The culture medium composition plays a significant role in the production of siderophores by Pseudomonas fluorescens DSM 50090. Succinate in minimal medium was found to be more effective for siderophore production compared to King B medium. However, changes in carbon sources like glycerol or dextrose in the minimal medium resulted in lower siderophore production. The regulation of siderophore production in P. fluorescens appears to be tightly controlled, suggesting that once a maximum concentration is reached, the bacterium is unable to produce more.
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
(2021)
Article
Limnology
Cybelle Menolli Longhini, Leo Mahieu, Fabian Sa, Constant M. G. van den Berg, Pascal Salaun, Renato Rodrigues Neto
Summary: The solubility of iron in coastal waters is greatly influenced by complexation with organic ligands, primarily humic substances. Mining activities can disrupt the natural biogeochemical cycle of iron, leading to high concentrations of dissolved and soluble iron fractions in water affected by mining catastrophes. The dominant presence of Fe(III) oxyhydroxides and Fe(III) complexes with amine compounds in the water column suggests alternative processes to explain the high dissolved iron concentrations in these affected coastal areas.
LIMNOLOGY AND OCEANOGRAPHY
(2021)
Review
Biotechnology & Applied Microbiology
Eduardo V. Soares, Helena M. V. M. Soares
Summary: The use of nanomaterials, including metal(loid) oxide nanoparticles, in consumer products has increased, leading to concerns about potential risks to human health and the environment. The review discusses the mechanisms underlying MOx NPs toxicity and highlights the use of yeast as a biological model in nanotoxicology. Recent scientific advances in understanding cellular responses to MOx NPs exposure are critically presented to provide insights into the impact of nanoparticles on eukaryotic cell physiology and metabolism. Discussions on current and future trends of MOx NPs toxicity and their potential impacts are also addressed.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2021)
Article
Engineering, Environmental
Bruno Monteiro, Liliana M. Martelo, Paulo M. S. Sousa, Margarida M. S. M. Bastos, Helena M. V. M. Soares
Summary: The study evaluated the efficiency of microwave assistance in delaminating waste printed circuit boards, showing microwave to be the most effective method. Optimized parameters resulted in faster and more efficient delamination of WPCBs into metallic and non-metallic components.
Article
Food Science & Technology
Marlene Costa, Sonia Losada-Barreiro, Julia Magalhaes, Luis S. Monteiro, Carlos Bravo-Diaz, Fatima Paiva-Martins
Summary: The study shows that catecholic phenolipids in olive oil-in-water emulsions are better antioxidants than their parent compounds, with octyl dihydrocaffeate showing the most significant improvement. The effective concentration of antioxidants in the interfacial region and the first anodic potential are important factors in predicting the antioxidant efficiency in such emulsions.
Article
Environmental Sciences
Arun Kumar, Md Samiur Rahman, Mohammad Ali, Pascal Salaun, Arthur Gourain, Suresh Kumar, Ranjit Kumar, Pintoo Kumar Niraj, Mukesh Kumar, Dhruv Kumar, Akhouri Bishwapriya, Shreya Singh, Krishna Murti, Sameer Dhingra, Maiko Sakamoto, Ashok Kumar Ghosh
Summary: The fast-growing arsenic menace in Bihar, India poses a serious health hazard to an estimated 10 million people. A recent study conducted in Chapar village of Samastipur district assessed the current situation of arsenic exposure and found significant health hazards among the exposed population, including skin manifestations, anemia, gastrointestinal issues, and diabetes. The study also revealed high levels of arsenic in groundwater, hair, and urine samples, with a high probability of carcinogenic-related risk among the population. The government provided two arsenic filter units based on the assessment report, offering a significant solution to the affected population.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Multidisciplinary Sciences
Jay C. Bullen, Lawrence N. Dworsky, Martijn Eikelboom, Matthieu Carriere, Alexandra Alvarez, Pascal Salaun
Summary: This study presents the use of an open-source potentiostat based on Arduino technology for arsenic detection in groundwater. By testing different types of gold electrodes with anodic stripping voltammetry, the microwire technique proves to be more accurate and precise than test strips in arsenic-contaminated groundwater, significantly reducing the false negative rate.
Article
Engineering, Environmental
Isabel F. F. Neto, Helena M. V. M. Soares
Summary: This study introduces an efficient and simple hydrometallurgical process for recycling gold from waste printed circuit boards, utilizing chlorination and ion-exchange steps. The process achieves high recovery rates and purities of gold, minimizing the number of steps and waste produced.
Article
Engineering, Environmental
Paulo M. S. Sousa, Liliana M. Martelo, Antonio T. Marques, Margarida M. S. M. Bastos, Helena M. V. M. Soares
Summary: The main aim of this work was to develop a simple, efficient, and environmentally friendly technology for recycling all main raw materials [gold, copper and fiber glass (FG) layers] from waste printed circuit boards (WPCBs). The process involved mechanical cutting, delamination, magnetic separation, leaching, and alkaline precipitation to separate and purify the different materials.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Environmental Sciences
Jeroen Bauwens, Luciana S. Rocha, Helena M. V. M. Soares
Summary: Petroleum spent catalysts may contain a significant amount of palladium (Pd), which is highly valuable and scarce. This study assessed the ability of a strong basic anionic resin to remove Pd from solution, and found that the resin showed high selectivity and good adsorption performance for Pd.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Ecology
Fengjie Liu, Martha Gledhill, Qiao-Guo Tan, Kechen Zhu, Qiong Zhang, Pascal Salaun, Alessandro Tagliabue, Yanjun Zhang, Dominik Weiss, Eric P. Achterberg, Yuri Korchev
Summary: The pH levels in the extracellular microenvironment surrounding phytoplankton cells (the phycosphere) differ slightly from bulk seawater. The difference is regulated by photosynthesis, extracellular enzymatic transformation of bicarbonate, as well as light intensity and seawater pH and buffering capacity. The pH change in the phycosphere alters Fe speciation and availability, which is crucial for assessing the sensitivity of marine phytoplankton to ocean acidification and Fe limitation.
Editorial Material
Plant Sciences
Eduardo V. Soares, Spyridon A. Petropoulos, Helena M. V. M. Soares
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Chemistry, Analytical
Claudia Maciel, Nadia F. D. Silva, Paula Teixeira, Julia M. C. S. Magalhaes
Summary: This study proposes a novel integrated system using loop-mediated isothermal amplification (LAMP) and a bacteriophage P100-magnetic platform, coupled with endpoint electrochemical techniques, for rapid detection of L. monocytogenes. Through validation in pasteurized milk spiked with L. monocytogenes, the system demonstrated outstanding performance and robustness, providing a rapid, portable, and cost-efficient detection scheme for decentralized on-field application.
Review
Materials Science, Multidisciplinary
Claudio M. R. Almeida, Julia M. C. S. Magalhaes, M. Fatima Barroso, Luisa Duraes
Summary: Amines are important compounds present in our daily intake and play a crucial role in controlling physiological functions. The development of sensor devices for monitoring these compounds is an important field of research. This study provides an overview of optical sensors for amine detection, with a focus on fluorimetric sensors based on lanthanide trivalent metal ions. Different matrices for hosting the optical elements are also discussed. Lanthanide complexes are capable of detecting various amines with low detection limits, although there is room for improvement in terms of selectivity and resolution.
JOURNAL OF MATERIALS CHEMISTRY C
(2022)
Article
Chemistry, Analytical
Yujia Ying, Huilin Li
Summary: Enzymes play a crucial role as biological catalysts in accelerating biochemical reactions in living organisms. This study proposes a convenient method for monitoring enzymatic catalytic processes using native top-down mass spectrometry. By exploring the heterogeneity of the chymotrypsin sample and using tandem mass spectrometry, the researchers were able to monitor covalent and noncovalent enzymatic complexes, substrates, and products during catalysis. The results demonstrate that this method has the potential to be a promising tool for characterizing biocatalysts.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Kang Yang, Shuaibo Shi, Jinyu Wu, Shaolong Han, Shengdi Tai, Shishen Zhang, Kun Zhang
Summary: H2O and D2O are important analogues closely related to various industries and monitoring fields. This study successfully distinguishes and detects H2O and D2O by designing a novel eu(III)-macrocycle with dual emitters, Eu-2a, and conducting fluorescence titration experiments.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Julia Kuligowski, Alvaro Perez-Rubio, Marta Moreno-Torres, Polina Soluyanova, Judith Perez-Rojas, Ivan Rienda, David Perez-Guaita, Eugenia Pareja, Ramon Trullenque-Juan, Jose Castell, Marcha Verheijen, Florian Caiment, Ramiro Jover, Guillermo Quintas
Summary: This study introduces a novel variable selection approach called cluster PLS (c-PLS) to assess the joint impact of variable groups selected based on biological characteristics on the predictive performance of a multivariate model. The usefulness of c-PLS is shown using miRNomic and metabolomic datasets obtained from the analysis of liver tissue biopsies.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Meixue Lai, Lijie Zhong, Siyi Liu, Yitian Tang, Tingting Han, Huali Deng, Yu Bao, Yingming Ma, Wei Wang, Li Niu, Shiyu Gan
Summary: This study presents a method for constructing wearable sweat electrolyte sensors using carbon fiber-based solid-contact ion-selective electrodes (SC-ISEs). By using carbon fibers extracted from commercial cloth as electrode material, the cost and reproducibility issues of flexible SC-ISEs were addressed. The results showed that the carbon fiber-based SC-ISEs exhibited reversible voltammetric and stable impedance performances, and had high reproducibility of standard potentials between normal and bending states.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Yang, Ying Liu, Min Deng, Peipei Wang, Dan Cheng, Songjiao Li, Longwei He
Summary: A near-infrared fluorescent probe has been developed to accurately measure the levels of peroxynitrite (ONOO-) in the endoplasmic reticulum (ER) in acute lung injury (ALI). The probe demonstrated rapid response, high selectivity, good sensitivity, and enhanced fluorescence intensity in response to ONOO-. It was successfully used to detect changes in ONOO- levels and showed significant increases in an ALI cell model and an ALI mouse model.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yanping Wang, Yuemei Chen, Kejun Li, Jinrong Zhou, Xin Yuan, Mei Zhang, Ke Huang
Summary: In this work, a portable analytical system based on point discharge chemical vapor generation atomic emission spectrometry (PD-CVG-AES) coupling with gold filament enrichment was designed. The highly sensitive analysis of Hg2+ indirectly realized the detection of ascorbic acid (AA). The measurement is based on the fact that Ag+ can decrease the concentration of Hg2+ by forming Ag-Hg amalgam in the presence of the reductant SnCl2, while AA can pre-reduce Ag+ to Ag0, leading to the generation of silver nanoparticles (Ag NPs). The developed novel analytical strategy broadens the application of microplasma-based AES and offers a higher level of sensitivity compared to current AA detection techniques.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yundi Huang, Bo Song, Kaiwen Chen, Deshu Kong, Jingli Yuan
Summary: This study developed two lysosome-targetable background-free TGL probes for efficient and accurate detection of 1O2, which can be used for monitoring endogenous 1O2 concentrations in lysosomes and discriminating variability induced by different photosensitizers. Furthermore, a smart luminescent sensor film was successfully prepared for on-site 1O2 production detection during PDT processes, offering a promising clinical monitoring tool for skin diseases.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Wei Lang, Jia-Mei Qin, Qian-Yong Cao
Summary: A novel polymer-based probe P1 was successfully synthesized for fluorescently ratiometric sensing of H2S with high selectivity and sensitivity. A smartphone sensing platform was constructed to conduct visual quantitative detection of H2S. P1 can be employed in evaluating the level fluctuations of H2S in living cells, testing water samples/wine samples, and monitoring food freshness.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yuanyuan Qin, Shuda Liu, Shuyun Meng, Dong Liu, Tianyan You
Summary: The study developed a split aptamer-based sandwich-type ratiometric biosensor for the detection of 17 beta-estradiol (E2) using photoelectrochemical and electrochemical assays. The biosensor utilized split aptamer fragments to recognize E2 and trigger a hybridization chain reaction, resulting in the production of double-stranded DNA labeled with CdTe quantum dots. This DNA complex was able to sensitize CdTe quantum dots and generate response signals for E2 detection. The developed biosensor demonstrated high sensitivity and accuracy with two linear ranges and low detection limits.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Siriwan Teepoo, Jongjit Jantra, Khaunnapa Panapong, David Taiwo Ajayi
Summary: A novel immunochromatographic assay based on hyperbranched Au plasmonic blackbodies with a smartphone readout was developed for rapid and sensitive detection of leucomalachite green residues in fish and shrimp products.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Andrea L. Larraga-Urdaz, Borja Moreira-Alvarez, Jorge Ruiz Encinar, Jose M. Costa-Fernandez, Maria Luisa Fernandez-Sanchez
Summary: A major challenge in the 21st century is the development of point-of-care diagnostic tools. In this study, a highly sensitive and simple bioassay using AuNPs and MNAzymes was developed for rapid detection and quantification of miRNA-4739. The proposed strategy shows potential for breast cancer diagnosis.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Xiaohan Zhao, Anyu Wang, Lingzi Zhai, Jiuhe Gao, Sizhe Lyu, Yingshan Jiang, Tian Zhong, Ying Xiao, Xi Yu
Summary: A novel method using polystyrene-coated magnetic nanoparticles for extracting monohydroxy polycyclic aromatic hydrocarbons from urine samples was investigated. The proposed method is simple, sensitive, and efficient, with desirable sensitivity for analyzing low-abundance metabolites in large volumes of complex urine samples.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Quan, Yuqing Zeng, Wenke Zhang, Fengfeng Li, Mengjiao Li, Zhihe Qing, Linlin Wu
Summary: In this study, a visual and reusable biosensor was developed for detecting substrates that are closely associated with human physiological health. The immobilized oxidase showed higher stability and sensitivity under harsh conditions, enabling reliable detection of substrates in complex fluids.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Dongjuan Wang, Xiuqian Ding, Jinling Xie, Juan Wang, Guanhao Li, Xin Zhou
Summary: In this study, a three-in-one sensor was developed for real-time detection of biogenic amines (BAs) with high sensitivity and selectivity. The sensor showed multimodal responses and could be used to fabricate portable devices for on-site non-destructive assessment of food spoilage indicators.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Jinting Meng, Zihao Xu, Shasha Zheng, Hongqun Yang, Tianfu Wang, Hong Wang, Yingwei Zhang
Summary: This study demonstrates the development of a cascade signal amplification system using a multi-pedal DNA walker and strand displacement reactions for the electrochemical detection of miRNA-155. The biosensor exhibited high sensitivity, selectivity, and the potential for clinical applications.
ANALYTICA CHIMICA ACTA
(2024)