Article
Microbiology
Alaa Baazeem, Esther Garcia-Cela, Angel Medina, Naresh Magan
Summary: The study explores the effect of temperature and water activity on in vitro growth and aflatoxin B-1 production of Aspergillus flavus isolated from pistachio nuts, as well as colonization and aflatoxin B-1 production in layers of raw pistachio nuts stored under different conditions. The findings can be used to identify high, intermediate, and low risk conditions for aflatoxin contamination in the pistachio nut processing chain.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Plant Sciences
M. Teresa Garcia-Lopez, Yong Luo, Alejandro Ortega-Beltran, Ramon Jaime, Juan Moral, Themis J. Michailides
Summary: This study developed a new qPCR method for accurately and efficiently quantifying the proportions of non-aflatoxin producing Aspergillus flavus AF36 in different substrates, which will help in precise management of aflatoxin contamination.
Article
Engineering, Multidisciplinary
Sahejad Patel, Yazeed Alnumay, Ahmed Al Brahim, Amjad Felemban, Ali J. Alrasheed, Hesham Jifri, Brian Parrott, Fadl Abdellatif
Summary: This paper proposes a sensor device for accurately measuring lateral offsets, primarily for the volumetric calibration of custody tanks in the energy industry. The device utilizes multiple 1-D photodiode arrays in a specific configuration to achieve sub-millimeter accuracy levels, and it is modular in design to address other measurement and alignment applications.
Article
Food Science & Technology
Alaa Baazeem, Alicia Rodriguez, Angel Medina, Naresh Magan
Summary: Under different climate-related abiotic factors, the growth and colonization of pistachio nuts by Aspergillus flavus strains showed no significant differences, but the production of aflatoxin B-1 (AFB(1)) significantly increased under specific conditions, especially at high temperature and high CO2 concentration.
Article
Engineering, Environmental
Chenhuan Wang, Jie Li, Qianqian Wang, Qiuhua Wu, Xiaodong Shi
Summary: A new fluorine-functionalized covalent organic framework (F-COF) was designed and fabricated for the first time, showing enhanced adsorption capability for aflatoxins. By coupling F-COF with high-performance liquid chromatography, a rapid and sensitive method for determining aflatoxins was established.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
Review
Food Science & Technology
Andrea Schincaglia, Juan Aspromonte, Flavio A. Franchina, Tatiana Chenet, Luisa Pasti, Alberto Cavazzini, Giorgia Purcaro, Marco Beccaria
Summary: This review provides an overview of the latest developments in aflatoxins analysis in the past decade, with a focus on nuts and nuts-related products. Aflatoxins, produced by certain strains of Aspergillus fungi, pose a serious health threat and are considered carcinogenic to humans. The control of aflatoxins in food commodities is a significant challenge in terms of quality control and economic losses. This review discusses crucial steps in aflatoxins analysis, including sampling, sample preparation, separation, and detection, and highlights the challenges associated with these steps.
Article
Chemistry, Applied
Fariba Sabzi, Diana Sirbu, Nikolai Kuhnert
Summary: A non-aqueous reversed-phase liquid chromatographic method coupled to electrospray ionization tandem mass spectrometry was used to identify triacylglycerols (TAGs) in pistachio lipids at the regioisomeric level. A two-dimensional (2D) map was employed for effective profiling of TAGs, specifically odd-numbered fatty acids and long-chain derivatives. TAGs were observed as pairs of regioisomers with distinct retention times and tandem mass spectra. Over 100 TAGs containing 26 fatty acids with 51-63 carbon atoms and 0-3 double bonds were identified in different pistachio samples. This method provides a fast and selective approach for quantifying complex TAGs in pistachio samples.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2023)
Article
Chemistry, Analytical
Bing-Bing Liu, Hai-Long Wu, Yue Chen, Tong Wang, Ru-Qin Yu
Summary: A second-order calibration model based on the ATLD-MCR model was proposed for the quantification of nine coumarins in Cnidii Fructus samples using HPLC-DAD. The method showed good linearity, rapidity, and accuracy, even in the presence of potential interfering species. Satisfactory qualitative and quantitative results were achieved in the presence of complex matrix interferences. The proposed method has the advantages of high efficiency, low cost, and meeting the requirements of green analytical chemistry.
MICROCHEMICAL JOURNAL
(2022)
Article
Biochemistry & Molecular Biology
Ana Rita Soares Mateus, Silvia Barros, Angelina Pena, Ana Sanches Silva
Summary: Pistachios are highly contaminated with mycotoxins, especially aflatoxins. A QuEChERS method combined with UHPLC-ToF-MS was developed for mycotoxin determination. Z-Sep d-SPE clean-up method showed the best analytical performance. The method was validated and found that pistachios in Portuguese markets are safe from mycotoxins.
Article
Pharmacology & Pharmacy
Ali Dini, Ali Esmaeili Nadimi, Khosro Behmaram
Summary: The Ministry of Health in Iran introduced a monitoring system to ensure safe pistachio consumption, with a certain percentage of aflatoxin contamination being detected over six consecutive years but posing low health risks to Europeans and Iranians.
IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH
(2021)
Article
Optics
D. A. Safronenkov, N. A. Borshchevskaya, T. Novikova, K. G. Katamadze, K. A. Kuznetsov, G. Kh Kitaeva
Summary: An experimental scheme and data processing approaches were proposed for measuring the normalized second-order correlation function of the biphoton field generated under spontaneous parametric down-conversion. Methods of discrimination of analog detection samples were developed to eliminate detection noises and obtain quantitatively true values of both the correlation function and the detector quantum efficiency. The methods were demonstrated depending on the type of detectors used in the SPDC channels.
Review
Chemistry, Analytical
Samuel W. Foster, Deklin Parker, Sangeeta Kurre, John Boughton, Dwight R. Stoll, James P. Grinias
Summary: Multi-dimensional liquid chromatography techniques are important for analyzing complex mixtures. The use of D-2 parallel column arrays allows for increased separation times and peak capacities without reducing the sampling rate. This method can also reduce total analysis time and increase complementarity.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Applied
H. M. Mnyandu, P. N. Mahlambi
Summary: QuEChERS and solid phase extraction (SPE) methods were optimized for the extraction of triazines in fruits and vegetables, showing good extraction efficiency and analytical performance. Both methods demonstrated stable recoveries, but QuEChERS, with fewer extraction steps, is more suitable for routine analysis of these pesticides.
Article
Chemistry, Analytical
B. N. Sundberg, R. Pause, I. D. van der Werf, A. Astefanei, K. J. van den Berg, M. R. van Bommel
Summary: Several analytical techniques have been compared for the identification of historical synthetic organic pigments (SOPs). The results indicate that specific combinations of analytical techniques are required for confident SOP identifications. The use of HRMS was found to be critical for the elucidation of unknown SOPs.
MICROCHEMICAL JOURNAL
(2021)
Article
Biochemical Research Methods
Andrea Cerrato, Sara Elsa Aita, Giuseppe Cannazza, Anna Laura Capriotti, Chiara Cavaliere, Cinzia Citti, Chiara Dal Bosco, Alessandra Gentili, Carmela Maria Montone, Roberta Paris, Aldo Lagana
Summary: Industrial hemp is being widely used for pharmaceutical and nutraceutical purposes, but the detailed composition of hemp remains poorly understood. In this study, the carotenoids and fat-soluble vitamins in the inflorescences of seven Italian industrial hemp varieties were analyzed. The most abundant carotenoids were found to be phytoene, phytofluene, and all-trans -a-carotene. In addition, several other carotenoids were tentatively identified using liquid chromatography coupled with photodiode-array detection.
JOURNAL OF CHROMATOGRAPHY A
(2023)
Article
Cell Biology
Mahsa Pourhamzeh, Samieh Asadian, Hamed Mirzaei, Azita Minaei, Elahe Shahriari, Anastasia Shpichka, Hamidreza Aboulkheyr Es, Peter Timashev, Moustapha Hassan, Massoud Vosough
Summary: Liver cancer is one of the most common types of cancer worldwide and often diagnosed at an advanced stage, limiting therapeutic options and resulting in poor prognosis. Radioimmunotherapy (RIT) using radiolabeled monoclonal antibodies or peptides offers a selective internal radiation therapy approach for liver cancer, potentially providing high therapeutic benefits with fewer side effects. Combined therapies involving immunotherapy and internal radiotherapy may enhance clinical outcomes in the future.
MOLECULAR AND CELLULAR BIOCHEMISTRY
(2023)
Review
Gastroenterology & Hepatology
Ensieh Zahmatkesh, Niloofar Khoshdel Rad, Nikoo Hossein-Khannazer, Mehdi Mohamadnejad, Roberto Gramignoli, Mustapha Najimi, Reza Malekzadeh, Moustapha Hassan, Massoud Vosough
Summary: According to the recent updates from the World Health Organization, liver diseases rank as the 12th most common cause of mortality. Orthotopic liver transplantation (OLT) is currently the most effective treatment for end-stage liver diseases. However, due to limitations such as limited organ donors, lifelong immunosuppression, and procedure complexity, cell and cell-derivative therapies have emerged as potential alternatives for liver diseases.
EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY
(2023)
Review
Engineering, Biomedical
Hadis Abdolahzadeh, Niloofar Khoshdel Rad, Anastasia Shpichka, Reihaneh Golroo, Kosar Rahi, Peter Timashev, Moustapha Hassan, Massoud Vosough
Summary: Cardiovascular diseases are the leading causes of premature deaths worldwide. Understanding current and future strategies for prevention, management, and monitoring of these diseases is crucial for public health. Cardiac tissue engineering, a multidisciplinary approach, is considered a novel alternative for cardiac regenerative medicine. This review highlights different cell types and approaches in cardiac regenerative medicine, discusses the application of cell-sheet-assisted cardiac tissue engineering in cardiac diseases, and explores how this technology can improve cardiac regeneration and function in preclinical and clinical models.
BIOMEDICAL MATERIALS
(2023)
Review
Medicine, Research & Experimental
Homeyra Seydi, Kosar Nouri, Niloufar Rezaei, Atena Tamimi, Moustapha Hassan, Hamed Mirzaei, Massoud Vosough
Summary: Treatment resistance is a major obstacle in therapeutic strategies for hepatocellular carcinoma. Chemotherapy and radiotherapy induce cell protective autophagy in HCC cells, leading to increased resistance. Multiple molecular pathways, including TGF-β, MAPK, NRF2, NF-κB, noncoding RNAs, EMT, drug transports, apoptosis evasion, DNA repair, cancer stem cells, and hypoxia, are involved in resistance induction and autophagy. Inhibition of autophagy may improve therapeutic outcomes in HCC patients by overcoming drug resistance.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Review
Biotechnology & Applied Microbiology
Nesa Fani, Maria Peshkova, Polina Bikmulina, Reihaneh Golroo, Peter Timashev, Massoud Vosough
Summary: This review discusses recent achievements in cartilage engineering and strategies for restoring cartilage defects. It focuses on cell types, biomaterials, and biochemical factors used to create cartilage tissue equivalents, as well as updates on fabrication techniques throughout the engineering process. The concept of personalized products created using a bioprinter, ECM-embedded autologous cell aggregates, and a bioreactor shows promise for improving cartilage tissue restoration. In situ platforms are also explored as a means to adjust newly formed tissue during surgery. While some achievements have progressed to clinical translation, further preclinical and clinical trials are expected in the future.
Article
Cell Biology
Neda Minaei, Roya Ramezankhani, Atena Tamimi, Abbas Piryaei, Ali Zarrabi, Amir Reza Aref, Ebrahim Mostafavi, Massoud Vosough
Summary: Hepatocellular carcinoma (HCC) is a common and deadly type of liver cancer. Conventional therapies have limited effectiveness, prompting the exploration of novel treatments like immunotherapy. However, the presence of an immunosuppressive tumor microenvironment has hindered the effectiveness of these approaches. Combining immune checkpoint inhibitors or immune checkpoint inhibitors with tyrosine kinase inhibitors has shown promise in overcoming these limitations.
EUROPEAN JOURNAL OF CELL BIOLOGY
(2023)
Review
Biotechnology & Applied Microbiology
Kasra Moeinabadi-Bidgoli, Radman Mazloomnejad, Alireza Beheshti Maal, Hamid Asadzadeh Aghdaei, Mandana Kazem Arki, Nikoo Hossein-Khannazer, Massoud Vosough
Summary: This article discusses the use of preconditioning and genetic modification strategies to enhance the therapeutic capacity of MSC-based therapy. Preconditioning involves culturing MSCs under sub-lethal conditions or treating them with specific drugs and biomolecules. Genetic modification involves transferring specific genetic sequences into MSCs to alter gene expression. Clinical trials using preconditioned and genetically modified MSCs are also discussed.
EXPERT OPINION ON BIOLOGICAL THERAPY
(2023)
Review
Cell Biology
Kasra Moeinabadi-Bidgoli, Malihe Rezaee, Nikoo Hossein-Khannazer, Amirhesam Babajani, Hamid Asadzadeh Aghdaei, Mandana Kazem Arki, Siamak Afaghi, Hassan Niknejad, Massoud Vosough
Summary: Ischaemic disorders are a significant global health burden that cannot be fully cured by current therapeutic approaches. Exosomes, with their multiple bioactive components, are considered as cell-free therapeutics and have the potential to be an ideal complementary therapeutic tool for ischemic disorders. Their convenience in storage and utilization, as well as their lack of cell therapy concerns, make them a promising approach for angiogenesis induction and other therapeutic functions in ischemic disorders.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
(2023)
Article
Pharmacology & Pharmacy
Niloufar Rezaei, Mandana Kazem Arki, Zohre Miri-Lavasani, Roya Solhi, Mahsa Khoramipour, Hamid Rashedi, Hamid Asadzadeh Aghdaei, Nikoo Hossein-Khannazer, Ebrahim Mostafavi, Massoud Vosough
Summary: This study aims to optimize treatment doses and overcome multidrug resistance in gastric cancer by developing an optimal niosomal formulation for doxorubicin and paclitaxel delivery. The results show that the drug-loaded niosomes have a higher release rate and can effectively inhibit tumor cell proliferation.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
(2023)
Article
Cell Biology
Mahtab Shahriari Felordi, Mehdi Alikhani, Zahra Farzaneh, Mahmoud Alipour Choshali, Marzieh Ebrahimi, Hamidreza Aboulkheyr Es, Abbas Piryaei, Mustapha Najimi, Massoud Vosough
Summary: The anti-cancer properties of EGCG involve induction of apoptosis, inhibition of cell proliferation and histone deacetylase. This study examined the role of EGCG in gastric cancer cells by dissociating the c-FLIP/Ku70 complex and found that EGCG induced apoptosis, changed the expression of various proteins involved in cell cycle regulation, and decreased the interaction between c-FLIP and Ku70 while increasing Ku70 nuclear content. By dissociating the c-FLIP/Ku70 complex, EGCG could improve the therapeutic outcome in combination with other cancer therapy protocols.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
(2023)
Review
Materials Science, Biomaterials
Roshanak Shams, Ali Behmanesh, Farid Najd Mazhar, Amir Ali Vaghari, Nikoo Hossein-Khannazer, Tarun Agarwal, Massoud Vosough, Jose M. Padron
Summary: This systematic review and meta-analysis examined the effectiveness of biomaterials integrated with specific microRNAs (miRNAs) for bone fracture repair treatment. 42 relevant papers were identified through a comprehensive search of PubMed, Web of Science, and Scopus databases. Hydrogel-based scaffolds, particularly those incorporating miR-26a, miR-21, and miR-22, showed significant benefits for bone repair. However, controversies and challenges in selecting appropriate miRNAs were observed. The study concludes that incorporating specific miRNAs into bone biomaterials enhances bone regeneration, but further trials are needed to validate their potential applications.
ACS BIOMATERIALS SCIENCE & ENGINEERING
(2023)
Review
Cell Biology
Mandana Kazem Arki, Kasra Moeinabadi-Bidgoli, Nikoo Hossein-Khannazer, Roberto Gramignoli, Mustapha Najimi, Massoud Vosough
Summary: The liver is responsible for various important functions in the body, and diseases affecting the liver can lead to inflammation, fibrosis, and eventually cirrhosis. The human amniotic membrane (hAM) has beneficial properties that can help treat chronic liver diseases, including its anti-fibrotic and anti-inflammatory effects. It can also be used as a scaffold for liver tissue engineering.
Review
Cell Biology
Mahsa Salehi, Zohre Miri Lavasani, Hani Keshavarz Alikhani, Bahare Shokouhian, Moustapha Hassan, Mustapha Najimi, Massoud Vosough
Summary: Liver cancer, particularly hepatocellular carcinoma (HCC), has become a leading cause of cancer-related deaths worldwide due to late diagnosis and limited therapeutic options. The use of circulating tumor cells (CTCs) holds promise for early detection, accurate prognosis, and monitoring of therapeutic responses in HCC patients. This review discusses the novel materials and technologies used for the isolation and detection of CTCs in HCC, as well as the clinical value of CTC detection.
Article
Biochemistry & Molecular Biology
Masoud Vazirzadeh, Negar Azarpira, Massoud Vosough, Kamran Ghaedi
Summary: This research aimed to differentiate mesenchymal stem cells (MSCs) into hepatocyte-like cells using galactosylated rat natural scaffolds and compare 2-D and 3-D cell culture methods. The study involved isolating and culturing Wharton's jelly cells from the umbilical cord, examining surface markers and adipogenic differentiation potential of MSCs, and culturing mesenchymal cells on galactosylated scaffolds. The findings showed that hepatocyte-like cells derived from 3D cultures on galactosylated scaffolds exhibited superior characteristics compared to cells in other culture conditions.
BIOCHEMISTRY AND BIOPHYSICS REPORTS
(2023)
Article
Cell Biology
Amir Bajouri, Dorsa Dayani, Anoushe Taj Sharghi, Shahedeh Karimi, Maryam Niknejadi, Kasra Moeinabadi Bidgoli, Hoda Madani, Fatemeh Abbasi Kakroodi, Tina Blourieh, Sura Mardpour, Neda Jaroughi, Nasser Aghdami, Leila Ataie-Fashtami, Saeid Shafiyan, Massoud Vosough
Summary: The safety and potential efficacy of injecting allogeneic adipose-derived mesenchymal stromal cells (ADSCs) in psoriatic patients were evaluated in this study. The results showed that after ADSCs injection, the lesions of the patients improved and no major adverse effects were observed. Additionally, the expression levels of pro-inflammatory factors in the patient blood samples were reduced, indicating modulation of inflammation after ADSCs administration. Overall, ADSC injection could be considered as a safe and effective therapeutic approach for psoriatic plaques.
Article
Chemistry, Analytical
Yujia Ying, Huilin Li
Summary: Enzymes play a crucial role as biological catalysts in accelerating biochemical reactions in living organisms. This study proposes a convenient method for monitoring enzymatic catalytic processes using native top-down mass spectrometry. By exploring the heterogeneity of the chymotrypsin sample and using tandem mass spectrometry, the researchers were able to monitor covalent and noncovalent enzymatic complexes, substrates, and products during catalysis. The results demonstrate that this method has the potential to be a promising tool for characterizing biocatalysts.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Kang Yang, Shuaibo Shi, Jinyu Wu, Shaolong Han, Shengdi Tai, Shishen Zhang, Kun Zhang
Summary: H2O and D2O are important analogues closely related to various industries and monitoring fields. This study successfully distinguishes and detects H2O and D2O by designing a novel eu(III)-macrocycle with dual emitters, Eu-2a, and conducting fluorescence titration experiments.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Julia Kuligowski, Alvaro Perez-Rubio, Marta Moreno-Torres, Polina Soluyanova, Judith Perez-Rojas, Ivan Rienda, David Perez-Guaita, Eugenia Pareja, Ramon Trullenque-Juan, Jose Castell, Marcha Verheijen, Florian Caiment, Ramiro Jover, Guillermo Quintas
Summary: This study introduces a novel variable selection approach called cluster PLS (c-PLS) to assess the joint impact of variable groups selected based on biological characteristics on the predictive performance of a multivariate model. The usefulness of c-PLS is shown using miRNomic and metabolomic datasets obtained from the analysis of liver tissue biopsies.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Meixue Lai, Lijie Zhong, Siyi Liu, Yitian Tang, Tingting Han, Huali Deng, Yu Bao, Yingming Ma, Wei Wang, Li Niu, Shiyu Gan
Summary: This study presents a method for constructing wearable sweat electrolyte sensors using carbon fiber-based solid-contact ion-selective electrodes (SC-ISEs). By using carbon fibers extracted from commercial cloth as electrode material, the cost and reproducibility issues of flexible SC-ISEs were addressed. The results showed that the carbon fiber-based SC-ISEs exhibited reversible voltammetric and stable impedance performances, and had high reproducibility of standard potentials between normal and bending states.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Yang, Ying Liu, Min Deng, Peipei Wang, Dan Cheng, Songjiao Li, Longwei He
Summary: A near-infrared fluorescent probe has been developed to accurately measure the levels of peroxynitrite (ONOO-) in the endoplasmic reticulum (ER) in acute lung injury (ALI). The probe demonstrated rapid response, high selectivity, good sensitivity, and enhanced fluorescence intensity in response to ONOO-. It was successfully used to detect changes in ONOO- levels and showed significant increases in an ALI cell model and an ALI mouse model.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yanping Wang, Yuemei Chen, Kejun Li, Jinrong Zhou, Xin Yuan, Mei Zhang, Ke Huang
Summary: In this work, a portable analytical system based on point discharge chemical vapor generation atomic emission spectrometry (PD-CVG-AES) coupling with gold filament enrichment was designed. The highly sensitive analysis of Hg2+ indirectly realized the detection of ascorbic acid (AA). The measurement is based on the fact that Ag+ can decrease the concentration of Hg2+ by forming Ag-Hg amalgam in the presence of the reductant SnCl2, while AA can pre-reduce Ag+ to Ag0, leading to the generation of silver nanoparticles (Ag NPs). The developed novel analytical strategy broadens the application of microplasma-based AES and offers a higher level of sensitivity compared to current AA detection techniques.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yundi Huang, Bo Song, Kaiwen Chen, Deshu Kong, Jingli Yuan
Summary: This study developed two lysosome-targetable background-free TGL probes for efficient and accurate detection of 1O2, which can be used for monitoring endogenous 1O2 concentrations in lysosomes and discriminating variability induced by different photosensitizers. Furthermore, a smart luminescent sensor film was successfully prepared for on-site 1O2 production detection during PDT processes, offering a promising clinical monitoring tool for skin diseases.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Wei Lang, Jia-Mei Qin, Qian-Yong Cao
Summary: A novel polymer-based probe P1 was successfully synthesized for fluorescently ratiometric sensing of H2S with high selectivity and sensitivity. A smartphone sensing platform was constructed to conduct visual quantitative detection of H2S. P1 can be employed in evaluating the level fluctuations of H2S in living cells, testing water samples/wine samples, and monitoring food freshness.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yuanyuan Qin, Shuda Liu, Shuyun Meng, Dong Liu, Tianyan You
Summary: The study developed a split aptamer-based sandwich-type ratiometric biosensor for the detection of 17 beta-estradiol (E2) using photoelectrochemical and electrochemical assays. The biosensor utilized split aptamer fragments to recognize E2 and trigger a hybridization chain reaction, resulting in the production of double-stranded DNA labeled with CdTe quantum dots. This DNA complex was able to sensitize CdTe quantum dots and generate response signals for E2 detection. The developed biosensor demonstrated high sensitivity and accuracy with two linear ranges and low detection limits.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Siriwan Teepoo, Jongjit Jantra, Khaunnapa Panapong, David Taiwo Ajayi
Summary: A novel immunochromatographic assay based on hyperbranched Au plasmonic blackbodies with a smartphone readout was developed for rapid and sensitive detection of leucomalachite green residues in fish and shrimp products.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Andrea L. Larraga-Urdaz, Borja Moreira-Alvarez, Jorge Ruiz Encinar, Jose M. Costa-Fernandez, Maria Luisa Fernandez-Sanchez
Summary: A major challenge in the 21st century is the development of point-of-care diagnostic tools. In this study, a highly sensitive and simple bioassay using AuNPs and MNAzymes was developed for rapid detection and quantification of miRNA-4739. The proposed strategy shows potential for breast cancer diagnosis.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Xiaohan Zhao, Anyu Wang, Lingzi Zhai, Jiuhe Gao, Sizhe Lyu, Yingshan Jiang, Tian Zhong, Ying Xiao, Xi Yu
Summary: A novel method using polystyrene-coated magnetic nanoparticles for extracting monohydroxy polycyclic aromatic hydrocarbons from urine samples was investigated. The proposed method is simple, sensitive, and efficient, with desirable sensitivity for analyzing low-abundance metabolites in large volumes of complex urine samples.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Quan, Yuqing Zeng, Wenke Zhang, Fengfeng Li, Mengjiao Li, Zhihe Qing, Linlin Wu
Summary: In this study, a visual and reusable biosensor was developed for detecting substrates that are closely associated with human physiological health. The immobilized oxidase showed higher stability and sensitivity under harsh conditions, enabling reliable detection of substrates in complex fluids.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Dongjuan Wang, Xiuqian Ding, Jinling Xie, Juan Wang, Guanhao Li, Xin Zhou
Summary: In this study, a three-in-one sensor was developed for real-time detection of biogenic amines (BAs) with high sensitivity and selectivity. The sensor showed multimodal responses and could be used to fabricate portable devices for on-site non-destructive assessment of food spoilage indicators.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Jinting Meng, Zihao Xu, Shasha Zheng, Hongqun Yang, Tianfu Wang, Hong Wang, Yingwei Zhang
Summary: This study demonstrates the development of a cascade signal amplification system using a multi-pedal DNA walker and strand displacement reactions for the electrochemical detection of miRNA-155. The biosensor exhibited high sensitivity, selectivity, and the potential for clinical applications.
ANALYTICA CHIMICA ACTA
(2024)
