Article
Chemistry, Applied
Zhenzhen Yao, Jixin Liu, Xuefei Mao, Guoying Chen, Zhihong Ma, Bingru Li
Summary: For the first time, separation and analysis of Hg2+ and methylmercury was achieved using in-line SPE-LC-AFS. The method was easy, compact, robust, and sensitive in mercury speciation analysis, ensuring food safety.
Article
Chemistry, Applied
Marina Pereira-Coelho, Isabel Cristina da Silva Haas, Cassia Katrin Reinke, Jocinei Dognini, Renata Dias de Mello Castanho Amboni, Luciano Vitali, Luiz Augusto dos Santos Madureira
Summary: A simple sample preparation approach employing the dispersive pipette extraction (DPX) technique is proposed to determine twelve polyphenols in wines. The extraction parameters were optimized using univariate and multivariate designs. The analytical performance was satisfactory with high determination coefficients and good precision.
Article
Chemistry, Applied
L. Perez-Mayan, M. Ramil, R. Cela, I. Rodriguez
Summary: The study utilized LC-MS/MS combined with online solid-phase extraction (SPE) strategy to detect potential pesticide residues in wine. The method showed high accuracy and provided good recovery rates for 90% of compounds under various parameter conditions.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2021)
Review
Chemistry, Inorganic & Nuclear
Anna A. Kotova, Didier Thiebaut, Jerome Vial, Antoine Tissot, Christian Serre
Summary: Analytical chemistry is crucial for separating complex mixtures, and Metal-organic frameworks (MOFs) are promising porous hybrid solids with unique physico-chemical properties, which can be applied in chromatography and solid-phase extraction to address challenges in these fields.
COORDINATION CHEMISTRY REVIEWS
(2022)
Article
Chemistry, Analytical
Abolghasem Jouyban, Mir Ali Farajzadeh, Mohammad Reza Afshar Mogaddam, Mahboob Nemati, Maryam Khoubnasabjafari, Vahid Jouyban-Gharamaleki
Summary: The study presents a solid phase extraction method utilizing a molecularly imprinted polymer and deep eutectic solvents-dispersive liquid-liquid microextraction for the extraction and quantification of valproic acid from exhaled breath condensate samples. The method demonstrated low limits of detection and quantification, good repeatability, accuracy, and stability. It was successfully applied to exhaled breath condensate samples from patients under valproic acid treatment.
MICROCHEMICAL JOURNAL
(2021)
Article
Food Science & Technology
Silvia Guazzotti, Cristina Pagliano, Francesco Dondero, Marcello Manfredi
Summary: This study evaluated the lipidomic profile of rice bran from the Italian rice variety, Roma, using ultra performance liquid chromatography-tandem mass spectrometry. Ethanol and methyl tert-butyl ether/methanol solvents were found to be excellent solvents for lipid extraction from rice bran, with ethanol being the most effective for triglycerides and N-acylethanolamines, and methyl tert-butyl ether/methanol being the most effective for diglycerides, phospholipids, and ceramides. Additionally, extraction with ethanol at 20 degrees C yielded similar results to extraction at 4 degrees C. Therefore, ethanol and methyl tert-butyl ether/methanol can be used to efficiently extract lipids from rice bran, contributing to the valorization of this by-product in a circular economy perspective.
Article
Environmental Sciences
Samia Mokh, Rania Nassar, Atika Berry, Mohammad El Khatib, Samah Doumiati, Mariam Taha, Raed Ezzeddine, Mohamad Al Iskandarani
Summary: The study utilized a solid-phase extraction method combined with liquid and gas chromatography-mass spectrometry to determine 18 organic UV filters in water samples, successfully detecting 8 target compounds. The method showed good recovery rates and acceptable repeatability and reproducibility, providing data support for future evaluation of UV filter residues in Lebanese swimming pools and their impact on the ecosystem.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Food Science & Technology
Laura Palacios Colon, Andres J. Rascon, Evaristo Ballesteros
Summary: Polycyclic aromatic hydrocarbons (PAHs) are priority pollutants due to their carcinogenic properties. A new method has been developed to detect and quantify 16 priority PAHs in commercial milk and dairy products, providing high precision and low detection limits.
Article
Chemistry, Multidisciplinary
Fangfang Zhu, Honglong Liu, Wenqing Zhang, Chuanyuan Du, Hao Zhu, Xiaodi Du, Xiaosong Hu, Yawei Lin
Summary: A novel BSMAD derivative was synthesized for the quantitative analysis of BAs in alcoholic beverages, and a HPLC method with low detection limit and excellent repeatability was successfully established. The method was applied for BA determination in various types of alcoholic beverages with satisfactory recoveries, providing a reliable and sensitive approach for future studies.
Article
Biochemical Research Methods
Milan Laurencik, Michal Kirchner, Peter Tolgyessy, Slavka Nagyova
Summary: The study developed and validated a method for determining priority polycyclic aromatic hydrocarbons (PAHs) using focused ultrasound solid-liquid extraction and dispersive solid-phase extraction followed by gas chromatography-triple quadrupole tandem mass spectrometry. The method is efficient, environmentally-friendly, and cost-effective, and can meet the requirements for PAHs in biota set by the EU.
JOURNAL OF CHROMATOGRAPHY A
(2022)
Article
Biochemical Research Methods
V Fernandez-Fernandez, M. Ramil, R. Cela, I Rodriguez
Summary: A modular solid-phase extraction (SPE) setup was developed to effectively extract neutrals, acids, and bases micro pollutants from wastewater. The approach showed excellent performance in extracting 64 compounds and identified 19 pollutants with low removal efficiencies during wastewater treatment or even enhancement.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Lidia Akemi Akamine, Deyber Arley Vargas Medina, Fernando Mauro Lancas
Summary: In this study, a graphene oxide/magnetite (GO-Fe3O4) nanocomposite was synthesized and utilized in the magnetic solid-phase extraction (MSPE) of gingerols from various ginger products. The developed MSPE method combined with HPLC-MS/MS analysis demonstrated high selectivity and consistent analytical confidence, with LODs ranging between 2 and 3 μg L-1. The technique showed good linearity, accuracy, and practicality, making it a valuable tool for quality control of commercial ginger-containing products.
Article
Chemistry, Multidisciplinary
Qingbao Yang, Yanhua Qi, Jingming Zhou, Yumei Chen, Chao Liang, Zhanxiang Liu, Xiaoli Zhang, Aiping Wang
Summary: A novel fluorescent immunochromatographic assay based on quantum dots was developed for the detection of fleroxacin residues in pork meat, showing good accuracy and specificity.
Article
Chemistry, Applied
Peng Sun, Zhao Yu, Chao Wang, Shuo Li
Summary: In this study, the content of eight sterols in rapeseed, including cholesterol, cholestanol, brassicasterol, ergosterol, campesterol, stigmasterol, 8-sitosterol, and stigmastanol, was determined using pressurized liquid extraction coupled with gas chromatography-mass spectrometry. The results showed a good linear relationship between the peak area and the corresponding mass concentration of the eight sterols. The developed method was efficient, simple, and accurate, suitable for the qualitative and quantitative analysis of sterols in rapeseed.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2023)
Article
Chemistry, Analytical
Akbar Badali, Afshin Javadi, Mohammad Reza Afshar Mogaddam, Zohreh Mashak
Summary: Metal organic framework based dispersive solid phase extraction combined with dispersive liquid-liquid microextraction was used for the extraction of aflatoxin M1 and ochratoxin A from milk samples, and the analytes were determined by high performance liquid chromatography-fluorescent detector. The method showed satisfactory results, including low limits of detection, good quantification, high extraction recoveries and enrichment factors, and good repeatability. The method was successfully applied for the quantification of aflatoxin M1 and ochratoxin A in various raw cow's milk samples, and the effect of microwave irradiations in decontaminating them from milk samples was studied.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Sebastian Riquelme, Vania Saez, Danilo Escobar, Carola Vergara, Cecilia Fuentealba, Luis Bustamante, Dietrich Von Baer, Paola Jara, Liliana Lamperti, Claudia Mardones
JOURNAL OF THE CHILEAN CHEMICAL SOCIETY
(2019)
Article
Biochemistry & Molecular Biology
Edaena Pamela Diaz-Galindo, Aleksandra Nesic, Gustavo Cabrera-Barjas, Claudia Mardones, Dietrich von Baer, Silvia Bautista-Banos, Octavio Dublan Garcia
Article
Plant Sciences
Felipe Noriega, Claudia Mardones, Susana Fischer, Cristina Garcia-Viguera, Diego A. Moreno, Maria Dolores Lopez
Summary: The study assessed how seasonal and local changes affect the content of bioactive compounds, thereby altering the aromatic quality and biological activity of the Chilean white strawberries.
JOURNAL OF BERRY RESEARCH
(2021)
Article
Polymer Science
Edaena Pamela Diaz-Galindo, Aleksandra Nesic, Gustavo Cabrera-Barjas, Octavio Dublan-Garcia, Rosa Isela Ventura-Aguilar, Francisco Javier Vazquez-Armenta, Saul Aguilar-Montes de Oca, Claudia Mardones, Jesus Fernando Ayala-Zavala
Article
Biochemistry & Molecular Biology
Lia Olivares-Caro, Claudia Radojkovic, Si Yen Chau, Daniela Nova, Luis Bustamante, Jose Yamil Neira, Andy J. Perez, Claudia Mardones
Article
Food Science & Technology
Danilo Escobar-Avello, Claudia Mardones, Vania Saez, Sebastian Riquelme, Dietrich von Baer, Rosa M. Lamuela-Raventos, Anna Vallverdu-Queralt
Summary: Grape canes, known as vine shoots, contain high levels of phenolic compounds that offer a range of health benefits. Extracts from grape canes obtained using a pilot-plant reactor were found to have a different phenolic profile compared to previous laboratory-scale studies. The extracts showed high antioxidant capacity and may potentially be used in the development of novel nutraceutical and pharmaceutical products, increasing the value and sustainability of these residues.
FOOD RESEARCH INTERNATIONAL
(2021)
Article
Biochemistry & Molecular Biology
Danilo Escobar-Avello, Javier Avendano-Godoy, Jorge Santos, Julian Lozano-Castellon, Claudia Mardones, Dietrich von Baer, Javiana Luengo, Rosa M. Lamuela-Raventos, Anna Vallverdu-Queralt, Carolina Gomez-Gaete
Summary: The study encapsulated grape cane pilot-plant extract in hydroxypropyl beta-cyclodextrin using spray-drying technique, resulting in improved stability and solubility of phenolic compounds with an encapsulation efficiency of 80.5%. The inclusion complex contained 42 compounds with high antioxidant capacity. This formulation has potential applications in water-soluble food and pharmaceutical products.
Article
Chemistry, Analytical
Carmina Vejar-Vivar, Luis Bustamante, Rafael Lucena, Christian Ortega, Mariela Valenzuela, Claudia Mardones
Summary: The combination of chromatography and mass spectrometry is widely used in forensic sciences due to its high sensitivity and selectivity, although it is time-consuming. Although the circumvention of chromatography can increase sample throughput using MEPS, the selectivity must be compensated by using HRMS and appropriate sample preparation steps.
MICROCHEMICAL JOURNAL
(2021)
Article
Biotechnology & Applied Microbiology
Javier Avendano-Godoy, Elisa Ortega, Manuel Urrutia, Danilo Escobar-Avello, Javiana Luengo, Dietrich von Baer, Claudia Mardones, Carolina Gomez-Gaete
Summary: This study aimed to improve the solubility and stability of the main stilbenes present in grape canes through the formation of inclusion complexes with cyclodextrins and subsequent polymeric microencapsulation.
FOOD AND BIOPRODUCTS PROCESSING
(2022)
Article
Biochemistry & Molecular Biology
Sebastian Riquelme, Jasna Campos, Lukasz Pecio, Rosa Alzamora, Claudia Mardones, Ana M. Simonet, Luis E. Arteaga-Perez, Rafael Rubilar, Oliver Fiehn, Andy J. Perez
Summary: Using untargeted metabolomics, this study revealed the systemic metabolic changes in pine species after infestation by Sirex noctilio. The immediate metabolome alteration was observed in needles, while wood tissues remained initially unchanged but collapsed after three months.
Article
Food Science & Technology
Daniela Nova-Baza, Lia Olivares-Caro, Luis Bustamante, Andy J. Perez, Carola Vergara, Jorge Fuentealba, Claudia Mardones
Summary: A comprehensive study on bioactive compounds in the leaves of main Berberis species growing in Chile was conducted. 117 compounds including phenolic acids, alkaloids, flavonols, and other compounds were identified. Hydroxycinnamic acid derivatives and quercetin derivatives were found to be the main compounds. Fatty acid profile and antioxidant capacity also varied among different species. These findings provide insights for novel approaches in utilizing these leaves as natural food or ingredient.
FOOD RESEARCH INTERNATIONAL
(2022)
Article
Chemistry, Analytical
Carmina Vejar-Vivar, Jaime Millan-Santiago, Claudia Mardones, Rafael Lucena, Soledad Cardenas
Summary: This study evaluates polydopamine inner wall-coated hypodermic needles as microextraction devices and electrospray ionization emitters for determining illicit drugs in oral fluid samples.
Article
Food Science & Technology
Javiera Gavilan, Claudia Mardones, Gabriela Oyarce, Sergio Trivino, Nicole Espinoza-Rubilar, Oscar Ramirez-Molina, Claudia Perez, Jose Becerra, Patricio Varas, Robinson Duran-Arcos, Carola Munoz-Montesino, Gustavo Moraga-Cid, Gonzalo E. Yevenes, Jorge Fuentealba
Summary: This study compares the properties of fresh and aged extracts from elephant garlic harvested on Chiloe Island, Chile. The aged extract showed a decrease in certain compounds and an increase in others, and exhibited higher antioxidant activity, increased cell viability, and improved neuronal function. The study provides scientific evidence to support the use of aged garlic extract from Chiloe Island as a functional food for brain health.
Article
Chemistry, Multidisciplinary
Carmina Vejar-Vivar, Maria Teresa Garcia-Valverde, Claudia Mardones, Rafael Lucena, Soledad Cardenas
Summary: In-needle microextraction using hypodermic needles coated with polydopamine was successfully applied to isolate six tricyclic antidepressants from oral fluid samples, achieving efficient preconcentration. Through in-depth study of various variables, optimal extraction conditions and calibration models were established, showing high precision and accuracy of the method.
Article
Chemistry, Analytical
Yujia Ying, Huilin Li
Summary: Enzymes play a crucial role as biological catalysts in accelerating biochemical reactions in living organisms. This study proposes a convenient method for monitoring enzymatic catalytic processes using native top-down mass spectrometry. By exploring the heterogeneity of the chymotrypsin sample and using tandem mass spectrometry, the researchers were able to monitor covalent and noncovalent enzymatic complexes, substrates, and products during catalysis. The results demonstrate that this method has the potential to be a promising tool for characterizing biocatalysts.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Kang Yang, Shuaibo Shi, Jinyu Wu, Shaolong Han, Shengdi Tai, Shishen Zhang, Kun Zhang
Summary: H2O and D2O are important analogues closely related to various industries and monitoring fields. This study successfully distinguishes and detects H2O and D2O by designing a novel eu(III)-macrocycle with dual emitters, Eu-2a, and conducting fluorescence titration experiments.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Julia Kuligowski, Alvaro Perez-Rubio, Marta Moreno-Torres, Polina Soluyanova, Judith Perez-Rojas, Ivan Rienda, David Perez-Guaita, Eugenia Pareja, Ramon Trullenque-Juan, Jose Castell, Marcha Verheijen, Florian Caiment, Ramiro Jover, Guillermo Quintas
Summary: This study introduces a novel variable selection approach called cluster PLS (c-PLS) to assess the joint impact of variable groups selected based on biological characteristics on the predictive performance of a multivariate model. The usefulness of c-PLS is shown using miRNomic and metabolomic datasets obtained from the analysis of liver tissue biopsies.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Meixue Lai, Lijie Zhong, Siyi Liu, Yitian Tang, Tingting Han, Huali Deng, Yu Bao, Yingming Ma, Wei Wang, Li Niu, Shiyu Gan
Summary: This study presents a method for constructing wearable sweat electrolyte sensors using carbon fiber-based solid-contact ion-selective electrodes (SC-ISEs). By using carbon fibers extracted from commercial cloth as electrode material, the cost and reproducibility issues of flexible SC-ISEs were addressed. The results showed that the carbon fiber-based SC-ISEs exhibited reversible voltammetric and stable impedance performances, and had high reproducibility of standard potentials between normal and bending states.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Yang, Ying Liu, Min Deng, Peipei Wang, Dan Cheng, Songjiao Li, Longwei He
Summary: A near-infrared fluorescent probe has been developed to accurately measure the levels of peroxynitrite (ONOO-) in the endoplasmic reticulum (ER) in acute lung injury (ALI). The probe demonstrated rapid response, high selectivity, good sensitivity, and enhanced fluorescence intensity in response to ONOO-. It was successfully used to detect changes in ONOO- levels and showed significant increases in an ALI cell model and an ALI mouse model.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yanping Wang, Yuemei Chen, Kejun Li, Jinrong Zhou, Xin Yuan, Mei Zhang, Ke Huang
Summary: In this work, a portable analytical system based on point discharge chemical vapor generation atomic emission spectrometry (PD-CVG-AES) coupling with gold filament enrichment was designed. The highly sensitive analysis of Hg2+ indirectly realized the detection of ascorbic acid (AA). The measurement is based on the fact that Ag+ can decrease the concentration of Hg2+ by forming Ag-Hg amalgam in the presence of the reductant SnCl2, while AA can pre-reduce Ag+ to Ag0, leading to the generation of silver nanoparticles (Ag NPs). The developed novel analytical strategy broadens the application of microplasma-based AES and offers a higher level of sensitivity compared to current AA detection techniques.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yundi Huang, Bo Song, Kaiwen Chen, Deshu Kong, Jingli Yuan
Summary: This study developed two lysosome-targetable background-free TGL probes for efficient and accurate detection of 1O2, which can be used for monitoring endogenous 1O2 concentrations in lysosomes and discriminating variability induced by different photosensitizers. Furthermore, a smart luminescent sensor film was successfully prepared for on-site 1O2 production detection during PDT processes, offering a promising clinical monitoring tool for skin diseases.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Wei Lang, Jia-Mei Qin, Qian-Yong Cao
Summary: A novel polymer-based probe P1 was successfully synthesized for fluorescently ratiometric sensing of H2S with high selectivity and sensitivity. A smartphone sensing platform was constructed to conduct visual quantitative detection of H2S. P1 can be employed in evaluating the level fluctuations of H2S in living cells, testing water samples/wine samples, and monitoring food freshness.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yuanyuan Qin, Shuda Liu, Shuyun Meng, Dong Liu, Tianyan You
Summary: The study developed a split aptamer-based sandwich-type ratiometric biosensor for the detection of 17 beta-estradiol (E2) using photoelectrochemical and electrochemical assays. The biosensor utilized split aptamer fragments to recognize E2 and trigger a hybridization chain reaction, resulting in the production of double-stranded DNA labeled with CdTe quantum dots. This DNA complex was able to sensitize CdTe quantum dots and generate response signals for E2 detection. The developed biosensor demonstrated high sensitivity and accuracy with two linear ranges and low detection limits.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Siriwan Teepoo, Jongjit Jantra, Khaunnapa Panapong, David Taiwo Ajayi
Summary: A novel immunochromatographic assay based on hyperbranched Au plasmonic blackbodies with a smartphone readout was developed for rapid and sensitive detection of leucomalachite green residues in fish and shrimp products.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Andrea L. Larraga-Urdaz, Borja Moreira-Alvarez, Jorge Ruiz Encinar, Jose M. Costa-Fernandez, Maria Luisa Fernandez-Sanchez
Summary: A major challenge in the 21st century is the development of point-of-care diagnostic tools. In this study, a highly sensitive and simple bioassay using AuNPs and MNAzymes was developed for rapid detection and quantification of miRNA-4739. The proposed strategy shows potential for breast cancer diagnosis.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Xiaohan Zhao, Anyu Wang, Lingzi Zhai, Jiuhe Gao, Sizhe Lyu, Yingshan Jiang, Tian Zhong, Ying Xiao, Xi Yu
Summary: A novel method using polystyrene-coated magnetic nanoparticles for extracting monohydroxy polycyclic aromatic hydrocarbons from urine samples was investigated. The proposed method is simple, sensitive, and efficient, with desirable sensitivity for analyzing low-abundance metabolites in large volumes of complex urine samples.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Quan, Yuqing Zeng, Wenke Zhang, Fengfeng Li, Mengjiao Li, Zhihe Qing, Linlin Wu
Summary: In this study, a visual and reusable biosensor was developed for detecting substrates that are closely associated with human physiological health. The immobilized oxidase showed higher stability and sensitivity under harsh conditions, enabling reliable detection of substrates in complex fluids.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Dongjuan Wang, Xiuqian Ding, Jinling Xie, Juan Wang, Guanhao Li, Xin Zhou
Summary: In this study, a three-in-one sensor was developed for real-time detection of biogenic amines (BAs) with high sensitivity and selectivity. The sensor showed multimodal responses and could be used to fabricate portable devices for on-site non-destructive assessment of food spoilage indicators.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Jinting Meng, Zihao Xu, Shasha Zheng, Hongqun Yang, Tianfu Wang, Hong Wang, Yingwei Zhang
Summary: This study demonstrates the development of a cascade signal amplification system using a multi-pedal DNA walker and strand displacement reactions for the electrochemical detection of miRNA-155. The biosensor exhibited high sensitivity, selectivity, and the potential for clinical applications.
ANALYTICA CHIMICA ACTA
(2024)