Article
Biochemical Research Methods
L. Perez-Mayan, G. Castro, M. Ramil, R. Cela, I Rodriguez
Summary: Two different analytical methodologies were evaluated for detecting GLY and AMPA residues in wine samples, with one utilizing derivative transformation and the other direct determination. The use of molecularly imprinted sorbent for extraction and a strong anionic exchange LC column for direct determination proved to be effective in overcoming the challenges presented by the wine matrix.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Sophie Catanese, Raoul K. Khanna, Antoine Lefevre, Hugo Alarcan, Pierre-Jean Pisella, Patrick Emond, Helene Blasco
Summary: To apply metabo-lipidomics in ophthalmological and systemic diseases, it is necessary to standardize the preanalytical and analytical steps in human tears. This study compared different methods for each step of the workflow and found that methanol/water extraction provided the best results for metabolomics, while Folch extraction was superior for lipidomics. The use of microcapillary glass tube for sampling was superior to Schirmer strip for metabolomics. A volume of 5 mu L provided satisfactory metabo-lipidomic coverage. These findings will contribute to improving the metabo-lipidomic workflow in human tears for the identification of new biomarkers.
Article
Food Science & Technology
Sufang Fan, Junmei Ma, Meirong Cao, Juan Wang, Leilei Zhang, Yan Zhang, Qiang Li, Jia Chen
Summary: A new liquid chromatography tandem mass spectrometry method was developed for the rapid and accurate determination of 15 pesticide residues in Chinese cabbage and cucumber samples. After QuEChERS extraction and online turbulent flow chromatography purification, the recoveries and matrix effects of pesticide residues were within acceptable ranges.
FOOD SCIENCE AND HUMAN WELLNESS
(2021)
Article
Biochemical Research Methods
Laura Carbonell-Rozas, Burkhard Horstkotte, Ana M. Garcia-Campana, Francisco J. Lara
Summary: In this work, an electrophoretic approach based on micellar electrokinetic chromatography coupled with tandem mass spectrometry (MEKC-MS/MS) was proposed for the simultaneous determination of nine neonicotinoids (NNIs) and the fungicide boscalid in pollen and honeybee samples. The method achieved improved separation efficiency and sensitivity through a stacking strategy and a scaled-down QuEChERS sample treatment. The results demonstrated that the proposed method is an environmentally friendly, efficient, sensitive, and useful alternative for the analysis of NNIs and boscalid.
JOURNAL OF CHROMATOGRAPHY A
(2022)
Article
Medical Laboratory Technology
Jordi Farre-Segura, Neus Fabregat-Cabello, Chiara Calaprice, Laurent Nyssen, Stephanie Peeters, Caroline Le Goff, Etienne Cavalier
Summary: A rapid and specific LC-MS/MS method for glucagon quantitation has been developed and validated, showing stability and accuracy in comparison to other immunoassay methods. This method could potentially establish a standardized approach for glucagon analysis in routine care settings.
CLINICA CHIMICA ACTA
(2021)
Article
Chemistry, Applied
L. Perez-Mayan, M. Ramil, R. Cela, I. Rodriguez
Summary: The study utilized LC-MS/MS combined with online solid-phase extraction (SPE) strategy to detect potential pesticide residues in wine. The method showed high accuracy and provided good recovery rates for 90% of compounds under various parameter conditions.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2021)
Article
Entomology
Bhumi D. Barad, Kaushik D. Parmar, Sanju S. Thorat, Nitesh S. Litoriya, Suchi Chawla
Summary: An experiment demonstrates that common household cooking techniques can reduce pesticide residues in rice. Traditional cooking with excess water is shown to be the most efficient method for reducing pesticide residues, effectively minimizing human exposure to pesticides.
JOURNAL OF STORED PRODUCTS RESEARCH
(2023)
Article
Food Science & Technology
Monika Kedzierska-Matysek, Anna Teter, Piotr Skalecki, Barbara Topyla, Piotr Domaradzki, Ewa Poleszak, Mariusz Florek
Summary: The levels of chemical pollutants in 30 samples of varietal honey from southeastern Poland were analyzed, and it was found that the residues of pesticides and heavy metals were within acceptable limits. The content of copper and zinc in honey varied significantly among different varieties.
Article
Biochemistry & Molecular Biology
Xuan Zhang, Yunhua Hui, Changling Fang, Yuan Wang, Feng Han, Xiaoyi Lou, Essy Kouadio Fodjo, Youqiong Cai, Cong Kong
Summary: A sensitive and reliable HPLC-MS/MS method was developed for the determination of methylene blue and its metabolite residues in aquatic products. The method showed good linearity, met European criteria, and was suitable for the detection of methylene blue and its metabolite residues in aquatic products.
Article
Biochemical Research Methods
Souleiman El Balkhi, Franck Saint-Marcoux
Summary: Chlordecone, an organochlorine insecticide used in French West Indies banana fields, has caused persistent pollution of soils and waters. People are mainly exposed to chlordecone through food and studies have shown that this exposure is associated with various health disorders. A new LC-MS/MS method with a low limit of detection has been developed to measure chlordecone in serum.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
(2023)
Article
Environmental Sciences
Sudip Bhattacharyya, Rajlakshmi Poi, Swagata Mandal, Moni Baskey (Sen), Dipak Kumar Hazra, Supradip Saha, Rajib Karmakar
Summary: A liquid-liquid extraction method was used to determine thirty-six multiclass pesticides in environmental waters of six urban areas in Nadia and North 24 Parganas districts. The highest presence of organochlorine and organophosphorus pesticide residues was found in river and pond water, with the monsoon season showing the highest levels of total pesticide residues. Risk assessment indicated chronic toxicity risk to river fishes due to high levels of endosulfan residues, while tube-well water samples were found to be safe for consumption with low levels of contamination.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Agriculture, Multidisciplinary
Rita Vegh, Csilla Soros, Nandor Majercsik, Laszlo Sipos
Summary: A multiresidue method for pesticide determination in bee pollen was developed and validated, and it was found that some samples contained banned pesticides, although they did not pose an acute risk on honeybees.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Environmental Sciences
Reza Pashaei, Reda Dzingeleviciene, Sajjad Abbasi, Malgorzata Szultka-Mlynska, Boguslaw Buszewski
Summary: An efficient, reliable, and sensitive analytical method has been developed to simultaneously determine 15 human pharmaceutical residues in fish and shrimp tissue samples. The method utilizes a liquid extraction procedure and optimized chromatographic conditions.
ENVIRONMENTAL MONITORING AND ASSESSMENT
(2022)
Article
Chemistry, Analytical
Anran Sheng, Qingqing Chen, Mengqi Yu, Ruiqi Xiao, Tianji Zhang, Zhiyu Wang, Robert J. Linhardt, Xiaojun Sun, Lan Jin, Lianli Chi
Summary: Glycosaminoglycans (GAGs) play a role in the treatment of many human diseases, especially in thrombosis, due to their anticoagulant activity. Novel electrophoresis-mass spectrometry methods have been developed to directly elucidate the structures of larger GAG chains with more biological importance, aiding in understanding the structure-activity relationship and quality control of GAG drugs.
ANALYTICAL CHEMISTRY
(2021)
Article
Biochemical Research Methods
Jufang Li, Aiping Xu, Jianyou Xue, Wei Qian, Ping Xu, Zhineng Hu, Chen Chen, Chaochao Wu
Summary: The paper proposes a novel method of deep eutectic solvent (DES)-assisted liquid-liquid extraction (LLE) coupled with liquid chromatography-tandem mass spectrometry (LC-MS/MS) for extracting steroid hormones from serum. The method has good linear calibration ranges, high extraction recoveries, and low limits of quantification, making it a simple and environmentally-friendly method.
JOURNAL OF CHROMATOGRAPHY A
(2023)
Article
Environmental Sciences
Maria Celeiro, Daniel Armada, Nuno Ratola, Thierry Dagnac, Jacob de Boer, Maria Llompart
Summary: This study analyzed target compounds in synthetic football pitches in Portugal, revealing the presence of various chemicals in crumb rubber and the potential risk of runoff water pollution to aquatic environment.
Article
Chemistry, Analytical
Daniel Armada, Maria Celeiro, Antia Martinez-Fernandez, Piyaluk Nurerk, Thierry Dagnac, Maria Llompart
Summary: An effective and sustainable air analysis method was developed to analyze volatile and semi-volatile organic compounds present in tire rubber and crumb rubber materials. The method, based on active sampling using a sorbent material and ultrasound-assisted extraction, showed no breakthrough within the studied interval and demonstrated linearity in a wide concentration range. It was successfully applied to various indoor and outdoor air environments, including a recycled rubber synthetic turf football pitch.
JOURNAL OF SEPARATION SCIENCE
(2021)
Article
Environmental Sciences
Maria Celeiro, Daniel Armada, Thierry Dagnac, Jacob de Boer, Maria Llompart
Summary: This study conducted a thorough chemical characterization of crumb rubber from different surfaces, finding that most of the recycled surfaces meet the limits proposed by the European Commission, but some exceed the maximum levels allowed for rubber consumer products. Additionally, numerous other hazardous compounds, including endocrine disruptors, were detected in the samples at parts per million concentrations.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Water Resources
Angeles Martinez-Organiz, Jose Elias Becerril Bravo, Maria Llompart, Thierry Dagnac, J. Pablo Lamas, Lua Vazquez, Laura Sampedro-Rosas
Summary: Different groups of emerging pollutants were identified in a municipal wastewater treatment plant in Acapulco, Mexico. Non-target compounds were detected, and the removal rates of four antibiotics were determined. Despite being a model plant, the WWTP was unable to completely remove all identified EPs from the effluent.
WATER QUALITY RESEARCH JOURNAL
(2021)
Article
Chemistry, Multidisciplinary
Lua Vazquez, Maria Celeiro, Meruyert Sergazina, Thierry Dagnac, Maria Llompart
Summary: An analytical miniaturized methodology based on solid-phase-microextraction coupled with gas chromatography-mass spectrometry has been developed for the identification of compounds in honey samples. By optimizing experimental parameters, the method was successfully validated for its suitability in analyzing a broad range of honey samples.
SUSTAINABLE CHEMISTRY AND PHARMACY
(2021)
Article
Biochemistry & Molecular Biology
Meruyert Sergazina, Lua Vazquez, Maria Llompart, Thierry Dagnac
Summary: Seventeen fungicides were detected in various matrices from vineyard areas using gas chromatography coupled to tandem mass spectrometry (GC-MS/MS). Ultrasound-assisted extraction (UAE) was utilized for leaf analysis, demonstrating its suitability for leaf crops across different types of samples. The study also revealed the diffusion and transport of fungicides in both crops and environmental matrices.
Article
Food Science & Technology
Lua Vazquez, Daniel Armada, Maria Celeiro, Thierry Dagnac, Maria Llompart
Summary: The study aimed to develop a miniaturized and environmentally friendly method to obtain the phenolic profile of Galician honeys, and evaluate their total phenolic content and antioxidant activity. Liquid chromatography-tandem mass spectrometry was used to quantify 41 target phenolic compounds, allowing for classification of different honeys based on their botanical origin.
Article
Chemistry, Analytical
Lua Vazquez, Maria Celeiro, Ana Castineira-Landeira, Thierry Dagnac, Maria Llompart
Summary: This research developed a simple, fast, and sustainable microextraction method for analyzing 60 personal care product compounds in hand sanitizers. The method was successfully validated and applied to real samples, revealing the lack of proper labeling and adherence to sanitizing recommendations.
ANALYTICA CHIMICA ACTA
(2022)
Article
Environmental Sciences
Vera Homem, Maria Llompart, Marlene Vila, Ana R. L. Ribeiro, Carmen Garcia-Jares, Nuno Ratola, Maria Celeiro
Summary: This study focused on the presence of personal care products (PCPs) in surface waters, specifically in four Portuguese rivers. Five classes of PCPs were monitored and several substances were detected at high concentrations, especially downstream of wastewater treatment plants discharge points.
Article
Biochemical Research Methods
Daniel Armada, Maria Celeiro, Thierry Dagnac, Maria Llompart
Summary: A fast, efficient, and simple air sampling methodology was developed to study volatile and semivolatile organic compounds in tire rubber materials and surfaces made of recycled tire rubber. The method showed good linearity, high precision, and accuracy, and could be completed in a short period of time. It is a sustainable approach that eliminates the use of organic solvents and generates minimal waste.
JOURNAL OF CHROMATOGRAPHY A
(2022)
Article
Environmental Sciences
Daniel Armada, Maria Llompart, Maria Celeiro, Pablo Garcia-Castro, Nuno Ratola, Thierry Dagnac, Jacob de Boer
Summary: This study assessed the presence of organic compounds in fill samples from synthetic turf football pitches, finding carcinogenic substances and endocrine disruptors in most rubber samples, indicating the presence of hazardous substances in recycled crumb rubber on a global scale.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Lua Vazquez, Maria Llompart, Thierry Dagnac
Summary: This study developed a method for analyzing multi-class antibiotics in water and validated its effectiveness. Non-target analysis and photodegradation experiments were also conducted, expanding the scope of the research.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Editorial Material
Biochemistry & Molecular Biology
Pilar Sandin-Espana, Thierry Dagnac
Article
Biochemistry & Molecular Biology
Maria Kalaboka, Vasilios Sakkas
Summary: With the advancement of technology and nanotechnology, new extraction sorbents have been created and effectively used for the magnetic solid-phase extraction of target analytes. In this study, graphene oxide (GO) magnetic composites and synthesized silica based magnetic nanoparticles (MNPs) were used as magnetic solid-phase extraction (MSPE) adsorbents for the preconcentration of emerging contaminants (ECs) in wastewater samples. The proposed methods achieved low quantitation limits and satisfactory recoveries, showing that it is suitable for the determination of target ECs in aquatic systems.
Article
Chemistry, Analytical
Yujia Ying, Huilin Li
Summary: Enzymes play a crucial role as biological catalysts in accelerating biochemical reactions in living organisms. This study proposes a convenient method for monitoring enzymatic catalytic processes using native top-down mass spectrometry. By exploring the heterogeneity of the chymotrypsin sample and using tandem mass spectrometry, the researchers were able to monitor covalent and noncovalent enzymatic complexes, substrates, and products during catalysis. The results demonstrate that this method has the potential to be a promising tool for characterizing biocatalysts.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Kang Yang, Shuaibo Shi, Jinyu Wu, Shaolong Han, Shengdi Tai, Shishen Zhang, Kun Zhang
Summary: H2O and D2O are important analogues closely related to various industries and monitoring fields. This study successfully distinguishes and detects H2O and D2O by designing a novel eu(III)-macrocycle with dual emitters, Eu-2a, and conducting fluorescence titration experiments.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Julia Kuligowski, Alvaro Perez-Rubio, Marta Moreno-Torres, Polina Soluyanova, Judith Perez-Rojas, Ivan Rienda, David Perez-Guaita, Eugenia Pareja, Ramon Trullenque-Juan, Jose Castell, Marcha Verheijen, Florian Caiment, Ramiro Jover, Guillermo Quintas
Summary: This study introduces a novel variable selection approach called cluster PLS (c-PLS) to assess the joint impact of variable groups selected based on biological characteristics on the predictive performance of a multivariate model. The usefulness of c-PLS is shown using miRNomic and metabolomic datasets obtained from the analysis of liver tissue biopsies.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Meixue Lai, Lijie Zhong, Siyi Liu, Yitian Tang, Tingting Han, Huali Deng, Yu Bao, Yingming Ma, Wei Wang, Li Niu, Shiyu Gan
Summary: This study presents a method for constructing wearable sweat electrolyte sensors using carbon fiber-based solid-contact ion-selective electrodes (SC-ISEs). By using carbon fibers extracted from commercial cloth as electrode material, the cost and reproducibility issues of flexible SC-ISEs were addressed. The results showed that the carbon fiber-based SC-ISEs exhibited reversible voltammetric and stable impedance performances, and had high reproducibility of standard potentials between normal and bending states.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Yang, Ying Liu, Min Deng, Peipei Wang, Dan Cheng, Songjiao Li, Longwei He
Summary: A near-infrared fluorescent probe has been developed to accurately measure the levels of peroxynitrite (ONOO-) in the endoplasmic reticulum (ER) in acute lung injury (ALI). The probe demonstrated rapid response, high selectivity, good sensitivity, and enhanced fluorescence intensity in response to ONOO-. It was successfully used to detect changes in ONOO- levels and showed significant increases in an ALI cell model and an ALI mouse model.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yanping Wang, Yuemei Chen, Kejun Li, Jinrong Zhou, Xin Yuan, Mei Zhang, Ke Huang
Summary: In this work, a portable analytical system based on point discharge chemical vapor generation atomic emission spectrometry (PD-CVG-AES) coupling with gold filament enrichment was designed. The highly sensitive analysis of Hg2+ indirectly realized the detection of ascorbic acid (AA). The measurement is based on the fact that Ag+ can decrease the concentration of Hg2+ by forming Ag-Hg amalgam in the presence of the reductant SnCl2, while AA can pre-reduce Ag+ to Ag0, leading to the generation of silver nanoparticles (Ag NPs). The developed novel analytical strategy broadens the application of microplasma-based AES and offers a higher level of sensitivity compared to current AA detection techniques.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yundi Huang, Bo Song, Kaiwen Chen, Deshu Kong, Jingli Yuan
Summary: This study developed two lysosome-targetable background-free TGL probes for efficient and accurate detection of 1O2, which can be used for monitoring endogenous 1O2 concentrations in lysosomes and discriminating variability induced by different photosensitizers. Furthermore, a smart luminescent sensor film was successfully prepared for on-site 1O2 production detection during PDT processes, offering a promising clinical monitoring tool for skin diseases.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Wei Lang, Jia-Mei Qin, Qian-Yong Cao
Summary: A novel polymer-based probe P1 was successfully synthesized for fluorescently ratiometric sensing of H2S with high selectivity and sensitivity. A smartphone sensing platform was constructed to conduct visual quantitative detection of H2S. P1 can be employed in evaluating the level fluctuations of H2S in living cells, testing water samples/wine samples, and monitoring food freshness.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yuanyuan Qin, Shuda Liu, Shuyun Meng, Dong Liu, Tianyan You
Summary: The study developed a split aptamer-based sandwich-type ratiometric biosensor for the detection of 17 beta-estradiol (E2) using photoelectrochemical and electrochemical assays. The biosensor utilized split aptamer fragments to recognize E2 and trigger a hybridization chain reaction, resulting in the production of double-stranded DNA labeled with CdTe quantum dots. This DNA complex was able to sensitize CdTe quantum dots and generate response signals for E2 detection. The developed biosensor demonstrated high sensitivity and accuracy with two linear ranges and low detection limits.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Siriwan Teepoo, Jongjit Jantra, Khaunnapa Panapong, David Taiwo Ajayi
Summary: A novel immunochromatographic assay based on hyperbranched Au plasmonic blackbodies with a smartphone readout was developed for rapid and sensitive detection of leucomalachite green residues in fish and shrimp products.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Andrea L. Larraga-Urdaz, Borja Moreira-Alvarez, Jorge Ruiz Encinar, Jose M. Costa-Fernandez, Maria Luisa Fernandez-Sanchez
Summary: A major challenge in the 21st century is the development of point-of-care diagnostic tools. In this study, a highly sensitive and simple bioassay using AuNPs and MNAzymes was developed for rapid detection and quantification of miRNA-4739. The proposed strategy shows potential for breast cancer diagnosis.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Xiaohan Zhao, Anyu Wang, Lingzi Zhai, Jiuhe Gao, Sizhe Lyu, Yingshan Jiang, Tian Zhong, Ying Xiao, Xi Yu
Summary: A novel method using polystyrene-coated magnetic nanoparticles for extracting monohydroxy polycyclic aromatic hydrocarbons from urine samples was investigated. The proposed method is simple, sensitive, and efficient, with desirable sensitivity for analyzing low-abundance metabolites in large volumes of complex urine samples.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Quan, Yuqing Zeng, Wenke Zhang, Fengfeng Li, Mengjiao Li, Zhihe Qing, Linlin Wu
Summary: In this study, a visual and reusable biosensor was developed for detecting substrates that are closely associated with human physiological health. The immobilized oxidase showed higher stability and sensitivity under harsh conditions, enabling reliable detection of substrates in complex fluids.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Dongjuan Wang, Xiuqian Ding, Jinling Xie, Juan Wang, Guanhao Li, Xin Zhou
Summary: In this study, a three-in-one sensor was developed for real-time detection of biogenic amines (BAs) with high sensitivity and selectivity. The sensor showed multimodal responses and could be used to fabricate portable devices for on-site non-destructive assessment of food spoilage indicators.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Jinting Meng, Zihao Xu, Shasha Zheng, Hongqun Yang, Tianfu Wang, Hong Wang, Yingwei Zhang
Summary: This study demonstrates the development of a cascade signal amplification system using a multi-pedal DNA walker and strand displacement reactions for the electrochemical detection of miRNA-155. The biosensor exhibited high sensitivity, selectivity, and the potential for clinical applications.
ANALYTICA CHIMICA ACTA
(2024)