Article
Chemistry, Multidisciplinary
Bin Du, Xihui Mu, Jianjie Xu, Shuai Liu, Zhiwei Liu, Zhaoyang Tong, Zhaofeng Wu, Zhi-Mei Qi
Summary: This article reports a label-free yet amplified in situ immunoassay strategy based on surface plasmon resonance (SPR) for sensitive and specific detection of human IgG (hIgG), an important serum marker for the diagnosis of certain diseases. The researchers constructed a wavelength-modulated Kretschman configuration SPR analyzer and fabricated Au film SPR biosensor chips. By monitoring the shift in resonance wavelength (lambda(R)), the biosensor achieved in situ real-time monitoring of hIgG with satisfactory sensitivity, excellent specificity, and stability. The operating principle of this research could have potential applications for detecting other targets of interest.
ARABIAN JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
F. Mousseau, C. Feraudet Tarisse, S. Simon, T. Gacoin, A. Alexandrou, C. I. Bouzigues
Summary: The use of lanthanide-doped nanoparticles as luminescent LFA probes offers higher sensitivity and measurement accuracy for detecting various biomolecules, including enterotoxins. Compared to gold nanoparticle-based LFAs, this method shows at least an order of magnitude improvement in analytical sensitivity and enables simultaneous quantitative detection of multiple biological toxins.
Article
Engineering, Electrical & Electronic
Roshni S. Babu, Hamish R. Colenso, Gideon J. Gouws, Baptiste Auguie, Ciaran P. Moore
Summary: This study investigated Ag-Au bimetallic surface plasmon resonance (SPR) sensors in the Kretschmann configuration. Ag-based sensors have high sensitivity but poor stability, while the addition of an Au capping layer improves chemical resistance and analyte bonding. Numerical modeling and experiments evaluated sensors with different Ag-Au thickness ratios, showing that the best SPR response was achieved with 45 nm Ag and 5 nm Au. The fabricated Ag-Au sensors were characterized, and the results were compared to single-layer Ag and Au sensors. The sensitivity of the thickness-optimized bimetallic layer was 1.5 times higher than that of the single-layer Au sensor.
IEEE SENSORS JOURNAL
(2023)
Article
Engineering, Electrical & Electronic
Yangang Ning, Huigai Guo, Yifan Qin, Yu Zhang, Shixiong Li, Jinhua Mou, Min Zhang, Yaxun Zhang, Zhihai Liu, Jianzhong Zhang, Xinghua Yang, Libo Yuan
Summary: This article presents an ultrasensitive fiber surface plasmon resonance (SPR) magnetic field sensor using an Au/TiO2 Schottky junction coated on a plastic-clad multimode fiber (PMF) and immersed in the magnetic fluid (MF). The sensor achieved a maximum magnetic sensitivity of -2.791 nm/Oe in the 5-35 Oe range, higher than most MF-based fiber magnetic field sensors. The proposed sensor can measure magnetic field strength variations with high sensitivity and accuracy, making it suitable for practical applications in various scenarios.
IEEE SENSORS JOURNAL
(2023)
Article
Environmental Sciences
Chi Ma, Jingjing Wei, Kainian Jiang, Zhongzhu Yang, Xu Yang, Kaihua Yang, Yi Zhang, Chang Zhang
Summary: In this study, a visible light responsive Au/BiOCOOH composite photocatalyst was prepared via hydrothermal method, showing significantly improved photocatalytic activity compared to bare BiOCOOH. The degradation rate constant of tetracycline hydrochloride was nearly 13.5 times higher for 2.0%Au/BiOCOOH. Analysis of intermediate products indicated a significant decrease in antibacterial ability with 2.0%Au/BiOCOOH.
Article
Chemistry, Physical
Bing Qiu, Chao Yuan, Mingtai Sun, Weijie Hu, Hua Tan, Suhua Wang
Summary: Due to their unique plasmonic properties, noble metals have become the preferred materials for applications in photovoltaics, photocatalysis, and sensors. In this study, gold (Au) monolayers with adjustable particle diameters and optical properties were successfully fabricated on transparent indium tin oxide (ITO) through a simple electrochemical deposition. The gold nanoparticles on ITO were spherical and isolated, identified as Au0 nanoparticles. The size and population density of the gold nanoparticles on ITO surface increased at lower current densities, resulting in higher light scattering.
APPLIED SURFACE SCIENCE
(2023)
Review
Chemistry, Inorganic & Nuclear
Abin Philip, A. Ruban Kumar
Summary: The necessity for the development of highly sensitive and selective detection techniques for the investigation of biomolecules is inevitable. Surface plasmon resonance (SPR) based biosensor has evolved as a sustainable and commercially applicable tool for this investigation. Exploring real-time, cost-effective, and time-efficient detection techniques is crucial for improving quality of life.
COORDINATION CHEMISTRY REVIEWS
(2022)
Article
Chemistry, Physical
Angelo Tricase, Davide Blasi, Alessandro Favia, Angela Stefanachi, Francesco Leonetti, Giuseppe Colafemmina, Luisa Torsi, Gaetano Scamarcio
Summary: The study investigated the synthesis of self-assembled monolayers of NMPA on Au films using infrared spectroscopy and found that the reaction yield was significantly influenced by the acidity of the EDC/NHSS solutions.
APPLIED SURFACE SCIENCE
(2021)
Article
Biophysics
Aabha Bajaj, Mohammad Abutoama, Sivan Isaacs, Marwan J. Abuleil, Karin Yaniv, Ariel Kushmaro, Martina Modic, Uros Cvelbar, Ibrahim Abdulhalim
Summary: Unwelcomed biofilms are a problem in environments where moisture is present, such as food industries and wastewater treatment plants. Advanced label-free sensors like surface plasmon resonance (SPR) have been explored for monitoring biofilm formation, but conventional noble metal SPR substrates have limited penetration depth, hindering reliable detection. In this study, a plasmonic insulator-metal-insulator (IMI) structure with higher penetration depth was proposed for portable SPR devices. The optimized IMI structure showed strong penetration dependence on wavelength and incidence angle, providing more reliable results compared to thin gold film substrates. The methodology can detect and characterize biofilms with better signal reliability.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Chemistry, Physical
Shirong Qin, Hanlun Xu, Mengjuan Liu, Nasir Ali, Yansong Chen, Sihan Zhao, Huizhen Wu
Summary: This study demonstrates the fabrication of a novel 2D-0D photodetector by combining 2D MoS2 with zero-dimensional PbSe quantum dots and Au nanocrystals. The mixed-dimensional photodetector shows high responsivity and detectivity in the near-infrared range, and a new carrier multiplication mechanism is identified. These findings provide a new route for designing high-performance optoelectronic devices based on CVD-grown MoS2.
APPLIED SURFACE SCIENCE
(2022)
Article
Chemistry, Physical
Zachary J. Woessner, Alexander N. Chen, Sara E. Skrabalak
Summary: Metal nanoparticles with different Au-Pd distributions were prepared and studied to evaluate the effect on refractive index sensitivity (RIS). It was found that the localization of Pd at LSPR hotspots is critical for achieving the highest RIS, with Pd-tipped Au octopods displaying the highest RIS and maintaining a moderate figure of merit. These findings emphasize the importance of Pd distribution in Au-Pd heterostructures for designing future LSPR sensors beyond the standard all-Au structures.
JOURNAL OF PHYSICAL CHEMISTRY C
(2021)
Article
Chemistry, Multidisciplinary
Baeck B. Choi, Bethy Kim, Yiqi Chen, Sung Jong Yoo, Younghyun Cho, Peng Jiang
Summary: In this study, the colloidal Langmuir-Blodgett coating process was used to fabricate Au-covered silica sphere monolayers and investigate the impact of silica diameter on surface plasmon resonance sensing sensitivity. The research found that larger silica sphere diameters and dipole mode exhibited higher sensitivity in surface plasmon resonance sensing applications.
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Lucia Sarcina, Pietro Delre, Giovanni Graziano, Angela Stefanachi, Davide Blasi, Rosaria A. A. Picca, Cinzia Di Franco, Francesco Leonetti, Gaetano Scamarcio, Paolo Bollella, Giuseppe F. F. Mangiatordi, Eleonora Macchia, Luisa Torsi
Summary: A variety of electronic and optoelectronic devices have been developed recently for biosensing applications, with a focus on a detecting interface that incorporates biorecognition elements anchored by self-assembled monolayers (SAMs) on a gold surface. This study investigates the effect of different SAM structures on the packing efficiency of antibodies and the analytical performance of sensors by performing surface plasmon resonance (SPR) characterization of anti-p24 anchored on these SAMs. The results show that the choice of SAM significantly affects the binding efficiency of antibodies against the HIV p24 protein, and density functional theory calculations provide a molecular understanding of these observations.
ADVANCED MATERIALS INTERFACES
(2023)
Article
Chemistry, Physical
Shilin Wang, Yuqing Han, Yusheng Luo, Yunfei Ma, Jinlong Zhang, Baozhu Tian
Summary: A novel surface plasmon resonance (SPR) photocatalyst Au(T)-TiO2(MS) was fabricated by anchoring Au thorns on TiO2 hierarchical microspheres (MS). The Au thorns not only respond to visible and NIR light but also effectively promote the separation of photogenerated charge carriers in TiO2(MS). The photocatalyst displays excellent bactericidal activity and stability under red and NIR light irradiation.
JOURNAL OF ALLOYS AND COMPOUNDS
(2022)
Article
Chemistry, Analytical
Suzuyo Inoue, Kenta Fukada, Katsuyoshi Hayashi, Michiko Seyama
Summary: This study developed a novel measuring and data-processing method for electrochemical surface plasmon resonance (EC-SPR), which can be used to detect sensor surfaces that are difficult to measure a specific SPR angle, especially for samples with non-uniform thickness and coloration like polymers. The proposed method combines SPR measurements with an electrochemical reaction to measure small molecules without increasing the number of measurement steps.
Article
Chemistry, Analytical
Yujia Ying, Huilin Li
Summary: Enzymes play a crucial role as biological catalysts in accelerating biochemical reactions in living organisms. This study proposes a convenient method for monitoring enzymatic catalytic processes using native top-down mass spectrometry. By exploring the heterogeneity of the chymotrypsin sample and using tandem mass spectrometry, the researchers were able to monitor covalent and noncovalent enzymatic complexes, substrates, and products during catalysis. The results demonstrate that this method has the potential to be a promising tool for characterizing biocatalysts.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Kang Yang, Shuaibo Shi, Jinyu Wu, Shaolong Han, Shengdi Tai, Shishen Zhang, Kun Zhang
Summary: H2O and D2O are important analogues closely related to various industries and monitoring fields. This study successfully distinguishes and detects H2O and D2O by designing a novel eu(III)-macrocycle with dual emitters, Eu-2a, and conducting fluorescence titration experiments.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Julia Kuligowski, Alvaro Perez-Rubio, Marta Moreno-Torres, Polina Soluyanova, Judith Perez-Rojas, Ivan Rienda, David Perez-Guaita, Eugenia Pareja, Ramon Trullenque-Juan, Jose Castell, Marcha Verheijen, Florian Caiment, Ramiro Jover, Guillermo Quintas
Summary: This study introduces a novel variable selection approach called cluster PLS (c-PLS) to assess the joint impact of variable groups selected based on biological characteristics on the predictive performance of a multivariate model. The usefulness of c-PLS is shown using miRNomic and metabolomic datasets obtained from the analysis of liver tissue biopsies.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Meixue Lai, Lijie Zhong, Siyi Liu, Yitian Tang, Tingting Han, Huali Deng, Yu Bao, Yingming Ma, Wei Wang, Li Niu, Shiyu Gan
Summary: This study presents a method for constructing wearable sweat electrolyte sensors using carbon fiber-based solid-contact ion-selective electrodes (SC-ISEs). By using carbon fibers extracted from commercial cloth as electrode material, the cost and reproducibility issues of flexible SC-ISEs were addressed. The results showed that the carbon fiber-based SC-ISEs exhibited reversible voltammetric and stable impedance performances, and had high reproducibility of standard potentials between normal and bending states.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Yang, Ying Liu, Min Deng, Peipei Wang, Dan Cheng, Songjiao Li, Longwei He
Summary: A near-infrared fluorescent probe has been developed to accurately measure the levels of peroxynitrite (ONOO-) in the endoplasmic reticulum (ER) in acute lung injury (ALI). The probe demonstrated rapid response, high selectivity, good sensitivity, and enhanced fluorescence intensity in response to ONOO-. It was successfully used to detect changes in ONOO- levels and showed significant increases in an ALI cell model and an ALI mouse model.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yanping Wang, Yuemei Chen, Kejun Li, Jinrong Zhou, Xin Yuan, Mei Zhang, Ke Huang
Summary: In this work, a portable analytical system based on point discharge chemical vapor generation atomic emission spectrometry (PD-CVG-AES) coupling with gold filament enrichment was designed. The highly sensitive analysis of Hg2+ indirectly realized the detection of ascorbic acid (AA). The measurement is based on the fact that Ag+ can decrease the concentration of Hg2+ by forming Ag-Hg amalgam in the presence of the reductant SnCl2, while AA can pre-reduce Ag+ to Ag0, leading to the generation of silver nanoparticles (Ag NPs). The developed novel analytical strategy broadens the application of microplasma-based AES and offers a higher level of sensitivity compared to current AA detection techniques.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yundi Huang, Bo Song, Kaiwen Chen, Deshu Kong, Jingli Yuan
Summary: This study developed two lysosome-targetable background-free TGL probes for efficient and accurate detection of 1O2, which can be used for monitoring endogenous 1O2 concentrations in lysosomes and discriminating variability induced by different photosensitizers. Furthermore, a smart luminescent sensor film was successfully prepared for on-site 1O2 production detection during PDT processes, offering a promising clinical monitoring tool for skin diseases.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Wei Lang, Jia-Mei Qin, Qian-Yong Cao
Summary: A novel polymer-based probe P1 was successfully synthesized for fluorescently ratiometric sensing of H2S with high selectivity and sensitivity. A smartphone sensing platform was constructed to conduct visual quantitative detection of H2S. P1 can be employed in evaluating the level fluctuations of H2S in living cells, testing water samples/wine samples, and monitoring food freshness.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yuanyuan Qin, Shuda Liu, Shuyun Meng, Dong Liu, Tianyan You
Summary: The study developed a split aptamer-based sandwich-type ratiometric biosensor for the detection of 17 beta-estradiol (E2) using photoelectrochemical and electrochemical assays. The biosensor utilized split aptamer fragments to recognize E2 and trigger a hybridization chain reaction, resulting in the production of double-stranded DNA labeled with CdTe quantum dots. This DNA complex was able to sensitize CdTe quantum dots and generate response signals for E2 detection. The developed biosensor demonstrated high sensitivity and accuracy with two linear ranges and low detection limits.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Siriwan Teepoo, Jongjit Jantra, Khaunnapa Panapong, David Taiwo Ajayi
Summary: A novel immunochromatographic assay based on hyperbranched Au plasmonic blackbodies with a smartphone readout was developed for rapid and sensitive detection of leucomalachite green residues in fish and shrimp products.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Andrea L. Larraga-Urdaz, Borja Moreira-Alvarez, Jorge Ruiz Encinar, Jose M. Costa-Fernandez, Maria Luisa Fernandez-Sanchez
Summary: A major challenge in the 21st century is the development of point-of-care diagnostic tools. In this study, a highly sensitive and simple bioassay using AuNPs and MNAzymes was developed for rapid detection and quantification of miRNA-4739. The proposed strategy shows potential for breast cancer diagnosis.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Xiaohan Zhao, Anyu Wang, Lingzi Zhai, Jiuhe Gao, Sizhe Lyu, Yingshan Jiang, Tian Zhong, Ying Xiao, Xi Yu
Summary: A novel method using polystyrene-coated magnetic nanoparticles for extracting monohydroxy polycyclic aromatic hydrocarbons from urine samples was investigated. The proposed method is simple, sensitive, and efficient, with desirable sensitivity for analyzing low-abundance metabolites in large volumes of complex urine samples.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Quan, Yuqing Zeng, Wenke Zhang, Fengfeng Li, Mengjiao Li, Zhihe Qing, Linlin Wu
Summary: In this study, a visual and reusable biosensor was developed for detecting substrates that are closely associated with human physiological health. The immobilized oxidase showed higher stability and sensitivity under harsh conditions, enabling reliable detection of substrates in complex fluids.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Dongjuan Wang, Xiuqian Ding, Jinling Xie, Juan Wang, Guanhao Li, Xin Zhou
Summary: In this study, a three-in-one sensor was developed for real-time detection of biogenic amines (BAs) with high sensitivity and selectivity. The sensor showed multimodal responses and could be used to fabricate portable devices for on-site non-destructive assessment of food spoilage indicators.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Jinting Meng, Zihao Xu, Shasha Zheng, Hongqun Yang, Tianfu Wang, Hong Wang, Yingwei Zhang
Summary: This study demonstrates the development of a cascade signal amplification system using a multi-pedal DNA walker and strand displacement reactions for the electrochemical detection of miRNA-155. The biosensor exhibited high sensitivity, selectivity, and the potential for clinical applications.
ANALYTICA CHIMICA ACTA
(2024)
