期刊
ANALYST
卷 144, 期 3, 页码 808-823出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8an01079j
关键词
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资金
- National Key RAMP
- D Program of China [2017YFC0906800]
- National Natural Science Foundation of China [21435002, 21727814, 21621003]
Advances in microfluidic techniques have prompted researchers to study the inherent heterogeneity of single cells in cell populations. This would be helpful in the identification of major diseases and the design of personalized medicine. Different microfluidic approaches provide a variety of functions in the process of single-cell analysis. In this review, we take a broad overview of various microfluidic-based approaches for single-cell isolation, single-cell lysis, and single-cell analysis. Up-to-date flagship techniques and the pros and cons of these methods are discussed in detail.
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