期刊
ANALYST
卷 138, 期 23, 页码 7066-7069出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3an01674a
关键词
-
资金
- Engineering and Physical Sciences Research Council (EPSRC)
FTIR chemical imaging has been demonstrated as a promising technique to construct automated systems to complement histopathological evaluation of biomedical tissue samples. The rapid chemical imaging of large areas of tissue has previously been a limiting factor in this application. Consequently, smaller areas of tissue have previously had to be sampled, possibly introducing sampling bias and potentially missing diagnostically important areas. In this report a high spatial resolution chemical image of a whole prostate cross section is shown comprising 66 million pixels. Each pixel represents an area 5.5 x 5.5 mu m(2) of tissue and contains a full infrared spectrum providing a chemical fingerprint. The data acquisition time was 14 hours, thus showing that a clinical time frame of hours rather than days has been achieved.
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