Structural comparison of two anti-CD20 monoclonal antibody drug products using middle-down mass spectrometry

Rapid comparison of a candidate biosimilar to an innovator monoclonal antibody with advanced liquid chromatography and mass spectrometry technologies

(2014) Hongwei Xie et al.   mAbs

Characterization of Therapeutic Antibodies and Related Products

(2012) Alain Beck et al.   ANALYTICAL CHEMISTRY

Evaluation of Intact Mass Spectrometry for the Quantitative Analysis of Protein Therapeutics

(2012) Ashley C. Gucinski et al.   ANALYTICAL CHEMISTRY

Rituximab

(2012) Nihal E. Abdulla et al.   BIODRUGS

Panitumumab: a summary of clinical development in colorectal cancer and future directions

(2012) Guillem Argiles et al.   Future Oncology

Annotation of a Serum N-Glycan Library for Rapid Identification of Structures

(2012) Danielle Aldredge et al.   JOURNAL OF PROTEOME RESEARCH

Marketing approval of mogamulizumab

(2012) Alain Beck et al.   mAbs

Fast analysis of recombinant monoclonal antibodies using IdeS proteolytic digestion and electrospray mass spectrometry

(2011) Guillaume Chevreux et al.   ANALYTICAL BIOCHEMISTRY

Structural Analysis of Intact Monoclonal Antibodies by Electron Transfer Dissociation Mass Spectrometry

(2011) Yury O. Tsybin et al.   ANALYTICAL CHEMISTRY

Characterization and Comparison of Disulfide Linkages and Scrambling Patterns in Therapeutic Monoclonal Antibodies: Using LC-MS with Electron Transfer Dissociation

(2011) Yi Wang et al.   ANALYTICAL CHEMISTRY

Antibody-based therapeutics to watch in 2011

(2011) Janice M. Reichert   mAbs

Rapid LC–MS screening for IgG Fc modifications and allelic variants in blood

(2011) Andrew M. Goetze et al.   MOLECULAR IMMUNOLOGY

Characterization of trisulfide modification in antibodies

(2010) Sheng Gu et al.   ANALYTICAL BIOCHEMISTRY

Identification and characterization of oxidation and deamidation sites in monoclonal rat/mouse hybrid antibodies

(2010) Vera Timm et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

High-Throughput Middle-Down Analysis Using an Orbitrap

(2010) Joe Cannon et al.   JOURNAL OF PROTEOME RESEARCH

Metrics for antibody therapeutics development

(2010) Janice M. Reichert   mAbs

The emerging process of Top Down mass spectrometry for protein analysis: biomarkers, protein-therapeutics, and achieving high throughput

(2010) John F. Kellie et al.   Molecular BioSystems

Mass measurement and top-down HPLC/MS analysis of intact monoclonal antibodies on a hybrid linear quadrupole ion trap-orbitrap mass spectrometer

(2009) Pavel V. Bondarenko et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Characterization of IgG1 Immunoglobulins and Peptide−Fc Fusion Proteins by Limited Proteolysis in Conjunction with LC−MS

(2008) Gerd R. Kleemann et al.   ANALYTICAL CHEMISTRY

Panitumumab: Human monoclonal antibody against epidermal growth factor receptors for the treatment of metastatic colorectal cancer

(2008) Mei Wu et al.   CLINICAL THERAPEUTICS

Tandem Mass Spectrometry with Ultrahigh Mass Accuracy Clarifies Peptide Identification by Database Retrieval

(2008) Michael T. Boyne et al.   JOURNAL OF PROTEOME RESEARCH

Precision proteomics: The case for high resolution and high mass accuracy

(2008) M. Mann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA