Article
Chemistry, Analytical
Qilin Wen, Dandan Li, Guidan Huang, Huai Xi, Hongcheng Pan, Lianming Zhang, Ziyuan Li, Xiaofen Xiao, Wenyuan Zhu
Summary: In this study, a dual amplification fluorescence strategy was proposed for the ultrasensitive detection of DNA adenine methylation methyltransferase (Dam MTase) activity. The method showed a low detection limit, good selectivity, and can be extended to the detection of other types of DNA MTases.
Article
Chemistry, Applied
Eda Erdemir, Garen Suna, Simay Gunduz, Musa Sahin, Songul Eglence-Bakir, Erman Karakus
Summary: The novel fluorescent probe TPA-TSC showed excellent selectivity for Hg2+ ions with a low detection limit, offering a promising method for accurately determining the quality of seafood and water samples polluted with mercury.
Article
Biochemical Research Methods
Reem F. Alshehri, Alaa S. Amin, Eman R. Darwish
Summary: Novel optical sensors incorporating 5-(2`-bromo-phenylazo)-6-hydroxypyrimidine-2,4-dione (I), 5-(2`,4`-dimethylphenylazo)-6-hydroxypyrimidine-2,4-dione (II), dibutylphthalate (DBP) and sodium tetra-phenylborate (Na-TPB) were developed for nickel determination. The addition of DBP greatly enhanced the performance of both ionophores I and II as chromo ionophores. The sensors exhibited excellent stability, reproducibility, long lifespan, and high selectivity for Ni2+ detection.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Hyun Kim, Ju Hye Jang, In Young Jung, Ju Hyun Cho
Summary: In this study, a highly selective KP peptide was screened using Klebsiella pneumoniae cells as a bait for detection of the bacterium. The specific interaction between KP peptide and K. pneumoniae lipopolysaccharide resulted in high sensitivity and specificity in detecting K. pneumoniae. Therefore, KP peptide holds promise as an alternative to antibodies in developing a biosensor system for K. pneumoniae detection.
Article
Green & Sustainable Science & Technology
Lijuan Feng, Hui Wang, Tingting Liu, Tiantian Feng, Meng Cao, Jiacheng Zhang, Tao Liu, Zhanhu Guo, Costas Galiotis, Yihui Yuan, Ning Wang
Summary: Strontium-90, a frequently released radioactive product in nuclear reactor waste, poses serious health hazards due to its long half-life and the ability to accumulate in the food chain and bones. However, its identification is challenging due to the absence of characteristic energy rays. In this study, the authors developed a biosensor that uses a fluorogenic dye, thioflavin T, to detect Sr2+ ions with high sensitivity and selectivity. This work provides a technological solution to monitor radioactive strontium pollution and contributes to the sustainability of nuclear power.
NATURE SUSTAINABILITY
(2023)
Article
Chemistry, Analytical
Dongmei Wang, Zhengjun Gong, Mi Tang, Wanli Fan, Bing Huang, Meikun Fan
Summary: Trace explosive detection is a hot topic in scientific communities due to its importance in homeland security. In this study, modified silver nanoparticles were used for the SERS detection of nitroaromatic explosives. It was found that halogen ions enhanced the detection signal by replacing surface adsorbates on the nanoparticles. With a LOD of only 2 femtomoles, this method shows great potential for ultrasensitive SERS detection of nitroaromatic explosives.
ANALYTICAL METHODS
(2022)
Article
Chemistry, Physical
Yuting Long, Hong Li, Wenbo Wang, Xinxin Yang, Zirui Liu
Summary: A novel methimazole-functionalized SERS optical fiber probe was developed for ultrasensitive determination of Cr(VI) with high stability and reproducibility, surpassing other reported techniques in terms of sensitivity.
JOURNAL OF ALLOYS AND COMPOUNDS
(2022)
Article
Chemistry, Analytical
Jing Liu, Chao Dou, Wei Chen, Han Yan, Wen-Zhuang Ma, Dan Meng, Xue-Qiu You, Yu-Shan Chen, Changjie Zhou, Pingping Zhuang
Summary: A novel nitrate sensor based on graphene field-effect transistors using triethylamine as the probe molecule was designed and fabricated. The sensor showed high sensitivity and specificity for nitrate anions, as well as other anions. The study provides an excellent technical means for the rapid, accurate, and real-time monitoring of water pollution caused by nitrate anions.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Applied
Jiulong Zhang, Daobin Zhang, Lin Xiao, Shouzhi Pu
Summary: The Ru-1 probe was designed to sensitively and selectively recognize HOCl in PBS solution, showing excellent water-solubility, low detection limit, long fluorescence lifetime, and large Stokes shift. Quantitative detection experiments in water samples indicated its potential application in the environment.
Article
Chemistry, Applied
Melasinee Laosuwan, Choosak Poonsawat, Rodjana Burakham, Supalax Srijaranai, Siriboon Mukdasai
Summary: A novel liquid colorimetric sensor based on deep eutectic solvent (DES) was developed for preconcentration and detection of Pb2+ in various food samples, showing advantages of simplicity, rapidity, environmental friendliness, and low cost.
Article
Biophysics
Muhit Rana, Tugba Yilmaz, Shirli Cohen, Sinem Beyhan, Avni A. Argun
Summary: Fungal infections pose a significant health concern, especially in immunocompromised population, and a rapid and accurate diagnostic method is needed to improve patient prognosis. In this study, we developed a cost-effective nucleic acid sensor that can detect histoplasmosis-causing fungal genes in whole blood or bronchoalveolar lavage samples earlier than current methods. The sensor uses immobilized nucleic acid probes to directly and label-free detect the presence of specific fungal genes through electrochemical analysis. It provides ultra-sensitive detection of DNA molecules with a limit of detection down to 100 aM, and the turnaround time for sample to result is less than 90 minutes, which is significantly faster than the current clinical procedure.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Chemistry, Analytical
Muhammad Azhar Hayat Nawaz, Lianjie Meng, Huipeng Zhou, Jia Ren, Sohail Anjum Shahzad, Akhtar Hayat, Cong Yu
Summary: A fluorometric method utilizing aggregation-induced emission probe based silica nanoparticles was developed for the detection of nitroaromatic explosives, showing that TPE-SiO2 nanoparticles exhibit better sensitivity towards picric acid. The study demonstrates that the TPE-SiO2 nanoparticles can be used as an excellent fluorescent probe for a wide range of electron-poor compounds, i.e. nitroaromatic compounds.
ANALYTICAL METHODS
(2021)
Article
Optics
Saeed Azad, Mahnaz Khosravi, Alireza Nikzad, Satyendra Kumar Mishra
Summary: In this study, a highly selective glucose detection fiber sensor was developed using molecular imprinting technique and carbon nano particles. The sensor works on a non-enzymatic approach and offers advantages such as low cost, online monitoring, fast response time, and high stability, making it a promising candidate for biological medicine measurements.
OPTICS AND LASER TECHNOLOGY
(2022)
Article
Chemistry, Analytical
Ruo-Jun Man, Meng-Ke Wu, Bing Yang, Yu-Shun Yang
Summary: In this work, a novel fluorescent probe TZPzine-1 was developed for selective detection of hydrazine in water samples and living cells, showing high sensitivity, wide linear range, and high selectivity. The probe also demonstrated rapid response and practical stability under various pH and temperature conditions.
Article
Chemistry, Multidisciplinary
Jianhua Zhu, Yunfei Bai, Xiuyu Chen, Linlin Hu, Wenjun Zhang, Chunyan Liu, Hua Shao, Jianguo Sun, Yun Chen
Summary: This study developed a mass-tagged probe-mediated enzyme- and light-assisted cascaded signal amplification strategy for the ultrasensitive detection of beta-lactamase, which is closely associated with drug-resistant bacteria. The sensitivity of beta-lactamase detection was significantly enhanced by this approach, and the released mass tags were quantified by mass spectrometry.
Article
Chemistry, Analytical
Niha Ansari, Anand Lodha, Alok Pandya, Pinkesh G. Sutariya, Shobhana K. Menon
ANALYTICAL METHODS
(2015)
Article
Medicine, Legal
Anand Lodha, Niha Ansari, Tejas Prajapati, M. V. Rao, Shobhana K. Menon
AUSTRALIAN JOURNAL OF FORENSIC SCIENCES
(2017)
Article
Chemistry, Multidisciplinary
Alok Pandya, Apritam Tripathi, Rahul Purohit, Sanjay Singh, Manjula I. Nandasiri, Ajay Karakoti, Surinder P. Singh, Rishi Shanker
Article
Biophysics
Niha Ansari, Anand Lodha, Shobhana K. Menon
BIOSENSORS & BIOELECTRONICS
(2016)
Article
Chemistry, Analytical
Pinkesh G. Sutariya, Alok Pandya, Anand Lodha, Shobhana K. Menon
Review
Chemistry, Analytical
Amitkumar N. Lad, Alok Pandya, Y. K. Agrawal
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2016)
Article
Medicine, Legal
Anand Lodha, Niha Ansari, Shahil Shah, M. V. Rao, Shobhana K. Menon
FORENSIC SCIENCE INTERNATIONAL
(2017)
Article
Chemistry, Multidisciplinary
Pinkesh G. Sutariya, Alok Pandya, Anand Lodha, Shobhana K. Menon
Article
Medicine, Legal
Niha Ansari, Nehal Trambadiya, Anand Lodha, S. K. Menon
Summary: The developed portable device using microfluidic paper-based analytical devices (muPADs) is sensitive, cost-effective, user-friendly, and suitable for field use. It can conduct blood detection tests and blood typing for ABO and Rh within minutes, providing a reliable alternative to lab-based tests at a fraction of the cost and complexity. The device is a valuable addition to conventional forensic and clinical investigations for on-site blood detection and typing.
AUSTRALIAN JOURNAL OF FORENSIC SCIENCES
(2021)
Article
Nanoscience & Nanotechnology
Niha Ansari, Anand Lodha, Tallika L. Patel
Summary: In this study, biocompatible, eco-friendly and cost-effective copper nanoparticles were synthesized using plant extract as a reducing agent. The synthesized nanoparticles showed high efficiency against both bacteria and fungi.
INTERNATIONAL JOURNAL OF NANOSCIENCE
(2022)
Article
Agriculture, Multidisciplinary
Nidhi Verma, Budhi Sagar Tiwari, Alok Pandya
Summary: Potato cultivation globally is severely affected by viruses, particularly Potato virus Y (PVY) causing significant economic losses. A newly designed vertical flow based immunodevice (VFID) offers rapid and accurate detection of PVY in potato plants. With great commercialization potential, the proposed VFID assay is a robust, specific, and affordable tool for early diagnosis of PVY in the agriculture sector.
ACS AGRICULTURAL SCIENCE & TECHNOLOGY
(2021)
Article
Medicine, Legal
Niha Ansari, Anand Lodha, Mitalee Mehta, Shobhana K. Menon
AUSTRALIAN JOURNAL OF FORENSIC SCIENCES
(2019)
Article
Chemistry, Analytical
N. Ansari, A. Lodha, A. Pandya, S. K. Menon
ANALYTICAL METHODS
(2017)
