4.6 Article

Ultrasensitive and selective colorimetric detection of thiourea using silver nanoprobes

期刊

ANALYST
卷 136, 期 24, 页码 5256-5260

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c1an15613f

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资金

  1. National Natural Science Foundation of China [21005031, 20903048]
  2. Fundamental Research Funds for the Central Universities [JUSRP21112]
  3. Opening Foundation of the State Key Laboratory of Analytical Chemistry for Life Science of Nanjing University [KLACLS1008]
  4. Youth Scientific Foundation of Jiangnan University [2009LQN11]

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A novel colorimetric thiourea (TU) sensor was developed utilizing citrate modified silver nanoparticles (AgNPs). The introduction of TU reduced the overall surface charges of the AgNPs, resulting in aggregation of AgNPs and a colorimetric response correlating with the concentration of TU. The detection of TU could be realized within 2 min, with an ultralow detection limit of 0.8 nM by the absorption method. In addition, the AgNPs sensor also showed good selectivity in the presence of potential interfering compounds. Since common steps such as modification and separation could be successfully avoided, the sensor developed here could provide a simple, cost-effective yet rapid and sensitive measurement tool for TU detection, and may provide new opportunities in the development of sensors for food safety and environmental monitoring in the future.

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