Review
Chemistry, Physical
Kun Qian, Randall E. Winans, Tao Li
Summary: Understanding the nanostructures of liquid electrolytes is crucial for enhancing electrochemical energy storage capacities, but the solvation structures and molecular dynamics in electrolytes are difficult to probe. Small-angle X-ray scattering (SAXS) offers unique insights into molecular clusters and ion pairs in electrolytes, with excellent time-resolution for studying molecular dynamics. This review focuses on the microscopic understanding of liquid electrolytes by SAXS and highlights the unique capabilities of X-ray scattering for nanostructure characterization.
ADVANCED ENERGY MATERIALS
(2021)
Article
Multidisciplinary Sciences
J. S. Park, J. D. Almer, K. C. James, L. J. Natanson, S. R. Stock
Summary: Members of subclass Elasmobranchii possess bioapatite mineralization in their cartilage skeletons, which has similar crystallography to bone but exhibits some differences. The mineral phase in shark centra has larger nanocrystallite sizes and is associated with less microstrain compared to bone.
JOURNAL OF THE ROYAL SOCIETY INTERFACE
(2022)
Article
Chemistry, Physical
Qi Han, Jack Binns, Jiali Zhai, Xingyu Guo, Timothy M. Ryan, Calum J. Drummond, Tamar L. Greaves
Summary: Solvents play a crucial role in protein instability and aggregation, and the development of quantitative, high throughput methods for evaluating protein aggregation in solvent systems, including viscous solvents, is important.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Biochemistry & Molecular Biology
Harald Rennhofer, Janea Kohnke, Jozef Keckes, Johannes Tintner, Christoph Unterweger, Thomas Zinn, Karl Deix, Helga Lichtenegger, Wolfgang Gindl-Altmutter
Summary: The utilization of low-cost carbon black from lignin relies heavily on the materials properties, such as pore structure and inner surfaces, which evolve with heat treatment temperature. The development of pore structure and graphitization increases with heat treatment temperature, leading to a shift in chemistry and bonding nature towards pure graphite. Heat treatment at 1600 degrees C may be sufficient for various applications, reducing production energy consumption while maintaining material properties.
Article
Materials Science, Multidisciplinary
Kakeru Obayashi, Kazutaka Kamitani, Chien-Wei Chu, Ryosuke Kawatoko, Chao-Hung Cheng, Atsushi Takahara, Ken Kojio
Summary: The internal structure of polyurethane adhesive undergoes changes during lap shear deformation, with an increase in the spacing of hard segment domains and the merging of tilt angle with the stretching direction. These findings are of great significance for the practical design of adhesives.
ACS APPLIED POLYMER MATERIALS
(2022)
Article
Biochemistry & Molecular Biology
Ish Kumar, Amin Sagar, Kanika Dhiman, Christopher R. Bethel, Andrea M. Hujer, Justin Carifi, Ashish, Robert Bonomo
Summary: Designing new beta-lactamase inhibitors (BLIs) is crucial to combat BL-mediated resistance. Small angle x-ray scattering (SAXS) in combination with molecular modeling can determine dynamic structures of macromolecules in solution and is useful in studying conformational changes in enzyme-inhibitor complexes. Our findings support the importance of exploring conformational changes using SAXS analysis in the design of future BLIs.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2023)
Review
Biochemistry & Molecular Biology
Ruixin Chen, Yang Song, Zhichun Wang, Hang Ji, Zhongyao Du, Qingwen Ma, Ying Yang, Xingxun Liu, Na Li, Yang Sun
Summary: This article systematically reviews various surfactant-macromolecule interactions and summarizes the principle and application of small-angle X-ray scattering (SAXS) in studying their structure. The SAXS integrative techniques have been widely used in analyzing the complex structure of surfactant-macromolecule interactions.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Physical
Johanna Schroeder, Rebecca K. Pittkowski, Isaac Martens, Raphael Chattot, Jakub Drnec, Jonathan Quinson, Jacob J. K. Kirkensgaard, Matthias Arenz
Summary: This study presents a combination of operando small- and wide-angle X-ray scattering to investigate the changes in mean particle sizes and phase fractions in fuel cell catalyst layers during accelerated stress tests. The results indicate that the degradation mechanism of the catalyst is classical Ostwald ripening via local diffusion of metal atoms on the support, rather than electrochemical Ostwald ripening. Furthermore, the study shows that the degradation of the catalyst layer is depth-dependent, suggesting the potential for future improvement of catalyst stability through a depth-dependent catalyst design.
Article
Chemistry, Physical
Simon Buchheiser, Max Philipp Deutschmann, Frank Rhein, Amanda Allmang, Michal Fedoryk, Bjoern Stelzner, Stefan Harth, Dimosthenis Trimis, Hermann Nirschl
Summary: The influence of different fuel-air equivalence ratios on particle morphology, size and degree of oxidation in an iron-air model burner is investigated. It is found that leaner combustion conditions lead to smaller particle size and higher degree of oxidation. Additionally, choosing a suitable particle size range can minimize residual iron content.
Article
Medicine, Research & Experimental
Dileep Urimi, Maja Hellsing, Najet Mahmoudi, Christopher Soderberg, Ronja Widenbring, Lars Gedda, Katarina Edwards, Thorsteinn Loftsson, Nicolaas Schipper
Summary: Lipid nanocapsules (LNCs) with core-shell structure were studied using various techniques, and it was found that drug loading does not alter the overall structure of LNCs. However, the presence of the drug leads to an increase in the thickness of the shell while the core size remains unchanged.
MOLECULAR PHARMACEUTICS
(2022)
Article
Multidisciplinary Sciences
David N. Azulay, Oliver Spaeker, Mnar Ghrayeb, Michaela Wilsch-Brauninger, Ernesto Scoppola, Manfred Burghammer, Ivo Zizak, Luca Bertinetti, Yael Politi, Liraz Chai
Summary: Biofilms are multicellular microbial communities encased in an extracellular matrix, with phenotypic heterogeneity enhancing their survival. The molecular structures, elemental distribution, and possible linkages within biofilms remain unexplored, showcasing the importance of molecular-level heterogeneity in shaping biofilm physiology and development.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Review
Chemistry, Physical
Josefine Eilso Nielsen, Vladimir Rosenov Koynarev, Reidar Lund
Summary: Peptide-lipid interactions are important for drug action and disease mechanisms, and model lipid membranes can provide insights into these interactions. Small-angle scattering techniques like SAXS/SANS have been used to study the effects of peptides on lipid bilayer structures with high resolution. This review summarizes recent advances in understanding complex peptide-lipid membrane interactions using SAXS/SANS methods and model lipid membranes, with a focus on data analysis and extracting quantitative information.
CURRENT OPINION IN COLLOID & INTERFACE SCIENCE
(2023)
Article
Chemistry, Analytical
Zhihong Li, Quanjie Jia, Ming Li
Summary: The conceptual design of a simple and powerful beamline for small angle X-ray scattering (SAXS) at the High Energy Photon Source (HEPS) in Beijing, China is described in this contribution. The design utilizes the high energy and low emittance features of the HEPS to simplify the beamline, increase beam flux and stability by omitting a monochromator and a focusing mirror. The pink beam from an in-air planar undulator is deflected by a V-shaped deflector and collimated by a set of three-slits to irradiate the sample, with scattering signals recorded by one or two detectors in a vacuum tube.
INSTRUMENTATION SCIENCE & TECHNOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Ezzeldin Metwalli, Klaus Goetz, Tobias Zech, Christian Baer, Isabel Schuldes, Anne Martel, Lionel Porcar, Tobias Unruh
Summary: A customized portable SAXS instrument has been constructed and tested at the D22 SANS instrument at ILL, with optimized lead shielding arrangement and double energy threshold X-ray detector to suppress high-energy gamma radiation background. The upgraded SAXS instrument allows for improved signal-to-noise ratio data and combined SAXS and SANS measurements, enabling simultaneous fitting of SAXS and SANS data from the same sample volume for unambiguous interpretation of scattering data. Advanced in situ/real time investigations are now possible, revealing time-resolved complementary nanoscale structural information.
APPLIED SCIENCES-BASEL
(2021)
Article
Biochemistry & Molecular Biology
Ying Li, Qike Li, Richard E. Gillilan, Alireza Abbaspourrad
Summary: This study reveals the reversible modulation of protein-protein and protein-chromophore interactions of Cphycocyanin (C-PC) from Spirulina platensis under hydrostatic pressure. The results show that high pressures can disassemble C-PC into monomers or detached subunits, accompanied by protein unfolding. The pressure-induced changes in structure and color can be precisely manipulated and reversed. This knowledge can be used to design new delivery and optical materials.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Physical
M. Antoniassi, K. F. R. Maciel, F. A. Manfre, A. C. F. Fagundes, A. L. C. Conceicao
RADIATION PHYSICS AND CHEMISTRY
(2019)
Article
Chemistry, Physical
A. C. F. Fagundes, L. M. Lopes, M. Antoniassi, R. S. Sousa, I. Mazzaro, A. L. C. Conceicao
RADIATION PHYSICS AND CHEMISTRY
(2019)
Article
Instruments & Instrumentation
R. D. Perez, G. E. Falchini, F. Cometto Vincente, L. Soares, M. E. Poletti, H. J. Sanchez
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS
(2019)
Article
Chemistry, Physical
L. D. H. Soares, M. S. S. Gobo, M. E. Poletti
RADIATION PHYSICS AND CHEMISTRY
(2020)
Article
Chemistry, Physical
Michel S. S. Gobo, L. D. H. Soares, M. E. Poletti
RADIATION PHYSICS AND CHEMISTRY
(2020)
Article
Chemistry, Physical
A. B. Mori, J. Kappke, T. A. Lima, M. Antoniassi, A. M. T. Ribeiro, R. Goulart, A. P. Galerani, G. Cardoso, A. L. Conceicao
RADIATION PHYSICS AND CHEMISTRY
(2020)
Article
Chemistry, Physical
F. Burille, J. J. M. Correa, P. Zambianchi, J. K. Zambianchi, M. Antoniassi
RADIATION PHYSICS AND CHEMISTRY
(2020)
Article
Engineering, Electrical & Electronic
Raquel de Paiva Corotti, Bruno Barros Cunha, Rafael Carvalho Barreto, Andre Luiz Coelho Conceicao, Ricardo Canute Kamikawachi
IEEE SENSORS JOURNAL
(2020)
Review
Chemistry, Multidisciplinary
Carlos Sanchez-Cano, Ramon A. Alvarez-Puebla, John M. Abendroth, Tobias Beck, Robert Blick, Yuan Cao, Frank Caruso, Indranath Chakraborty, Henry N. Chapman, Chunying Chen, Bruce E. Cohen, Andre L. C. Conceicao, David P. Cormode, Daxiang Cui, Kenneth A. Dawson, Gerald Falkenberg, Chunhai Fan, Neus Feliu, Mingyuan Gao, Elisabetta Gargioni, Claus-C Glueer, Florian Gruener, Moustapha Hassan, Yong Hu, Yalan Huang, Samuel Huber, Nils Huse, Yanan Kang, Ali Khademhosseini, Thomas F. Keller, Christian Koernig, Nicholas A. Kotov, Dorota Koziej, Xing-Jie Liang, Beibei Liu, Sijin Liu, Yang Liu, Ziyao Liu, Luis M. Liz-Marzan, Xiaowei Ma, Andres Machicote, Wolfgang Maison, Adrian P. Mancuso, Saad Megahed, Bert Nickel, Ferdinand Otto, Cristina Palencia, Sakura Pascarelli, Arwen Pearson, Oula Penate-Medina, Bing Qi, Joachim Raedler, Joseph J. Richardson, Axel Rosenhahn, Kai Rothkamm, Michael Rubhausen, Milan K. Sanyal, Raymond E. Schaak, Heinz-Peter Schlemmer, Marius Schmidt, Oliver Schmutzler, Theo Schotten, Florian Schulz, A. K. Sood, Kathryn M. Spiers, Theresa Staufer, Dominik M. Stemer, Andreas Stierle, Xing Sun, Gohar Tsakanova, Paul S. Weiss, Horst Weller, Fabian Westermeier, Ming Xu, Huijie Yan, Yuan Zeng, Ying Zhao, Yuliang Zhao, Dingcheng Zhu, Ying Zhu, Wolfgang J. Parak
Summary: X-ray-based analytics are widely used in physics, chemistry, materials science, and engineering, but their full potential in life sciences and medicine has not been fully utilized. Current and upcoming advances in applying these techniques to investigate the nano-bio interface are discussed, along with addressing current limitations and potential strategies for future in vivo use.
Article
Chemistry, Physical
G. E. Falchini, A. Malezan, M. E. Poletti, E. Soria, M. Pasqualini, R. D. Perez
Summary: The study developed an analytical procedure for spatial quantification of phosphorous in cancerous tissues using micro-XRF, successfully applied to murine mammary gland adenocarcinoma samples. The technique detected elevated phosphorous content in tumor tissues, associated with areas of active tumor cells, providing valuable information for studying tumor growth and progression.
RADIATION PHYSICS AND CHEMISTRY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
A. L. C. Conceicao, J. Perlich, S. Haas, S. S. Funari
BIOMEDICAL PHYSICS & ENGINEERING EXPRESS
(2020)
Proceedings Paper
Engineering, Mechanical
Z. Hegedues, T. Mueller, J. Hektor, E. Larsson, T. Baecker, S. Haas, A. L. C. Conceicao, S. Gutschmidt, U. Lienert
40TH RISO INTERNATIONAL SYMPOSIUM ON MATERIALS SCIENCE: METAL MICROSTRUCTURES IN 2D, 3D AND 4D
(2019)
Article
Multidisciplinary Sciences
A. L. C. Conceicao, K. Meehan, M. Antoniassi, M. Piacenti-Silva, M. E. Poletti