期刊
ANAIS BRASILEIROS DE DERMATOLOGIA
卷 86, 期 6, 页码 1243-1246出版社
SOC BRASILEIRA DERMATOLOGIA
DOI: 10.1590/S0365-05962011000600037
关键词
Botulinum toxins; type A; Hyperhidrosis; Iontophoresis; Phonophoresis
类别
Idiopathic palmar hyperhidrosis is a common disease that exerts a considerable effect on patients' quality of life. The definitive treatment of this condition (sympathectomy) is associated with some adverse effects and surgical risks. Drugs such as onabotulinumtoxinA can be percutaneously delivered by phonophoresis or by iontophoresis and may be useful in the treatment of hyperhidrosis. In this paper, the authors describe four cases in which an objective and subjective improvement in sweating was seen following 10 daily sessions of phonophoresis or iontophoresis. No adverse effects were reported. The clinical results achieved with treatment were maintained over 16 weeks of follow-up after the end of treatment. Percutaneous drug delivery techniques should be perceived as an option for the treatment of dermatologic conditions.
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