Similar physiological effects in Porphyromonas gingivalis ATCC 33277 under hemin-excess and hemin-limited concentrations are putatively associated to different hydrogen peroxide function

Porphyromonas gingivalis requires optimal hemin to grow while non-optimal hemin hampers growth. Hemin induces H2O2 production while H2O2 has a dual function. In P. gingivalis ATCC 33277, we found similar physiological effects under hemin-excess and hemin-limited concentrations which we propose is related to two different functions of the H2O2 molecule. (C) 2014 Elsevier Ltd. All rights reserved.