Structure–activity relationships in ultrashort cationic lipopeptides: the effects of amino acid ring constraint on antibacterial activity

Discovery of novel histidine-derived lipo-amino acids: Applied in the synthesis of ultra-short antimicrobial peptidomimetics having potent antimicrobial activity, salt resistance and protease stability

(2013) Mija Ahn et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Cyclic lipopeptides as antibacterial agents – Potent antibiotic activity mediated by intriguing mode of actions

(2013) Tanja Schneider et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Antimicrobial susceptibility of 22746 pathogens from Canadian hospitals: results of the CANWARD 2007-11 study

(2013) G. G. Zhanel et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Polyproline-II Helix in Proteins: Structure and Function

(2013) Alexei A. Adzhubei et al.   JOURNAL OF MOLECULAR BIOLOGY

Ultrashort Cationic Lipopeptides and Lipopeptoids Selectively Induce Cytokine Production in Macrophages

(2013) Brandon Findlay et al.   PLoS One

A call for antibiotic alternatives research

(2013) Thaddeus B. Stanton   TRENDS IN MICROBIOLOGY

Antimicrobial peptides: Their physicochemical properties and therapeutic application

(2012) Su-Jin Kang et al.   ARCHIVES OF PHARMACAL RESEARCH

Investigating the antimicrobial peptide ‘window of activity’ using cationic lipopeptides with hydrocarbon and fluorinated tails

(2012) Brandon Findlay et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Synthetic Mimics of Antimicrobial Peptides with Immunomodulatory Responses

(2012) Hitesh D. Thaker et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Guanidylation and Tail Effects in Cationic Antimicrobial Lipopeptoids

(2012) Brandon Findlay et al.   PLoS One

Multifunctional cationic host defence peptides and their clinical applications

(2011) Amy T. Y. Yeung et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The antibiotic R&D pipeline: an update

(2011) Daniela Jabes   CURRENT OPINION IN MICROBIOLOGY

The expanding scope of antimicrobial peptide structures and their modes of action

(2011) Leonard T. Nguyen et al.   TRENDS IN BIOTECHNOLOGY

Modulation of interleukin-1β-induced inflammatory responses by a synthetic cationic innate defence regulator peptide, IDR-1002, in synovial fibroblasts

(2011) Emily Turner-Brannen et al.   ARTHRITIS RESEARCH & THERAPY

Prevalence of Antimicrobial-Resistant Pathogens in Canadian Hospitals: Results of the Canadian Ward Surveillance Study (CANWARD 2008)

(2010) G. G. Zhanel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Cationic Amphiphiles, a New Generation of Antimicrobials Inspired by the Natural Antimicrobial Peptide Scaffold

(2010) B. Findlay et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antimicrobial Activity of Short, Synthetic Cationic Lipopeptides

(2010) Garry Laverty et al.   Chemical Biology & Drug Design

Host defense peptides and their antimicrobial-immunomodulatory duality

(2010) Lars Steinstraesser et al.   IMMUNOBIOLOGY

ContiguousO-Galactosylation of 4(R)-Hydroxy-l-proline Residues Forms Very Stable Polyproline II Helices

(2010) Neil W. Owens et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Antibacterial Activity of Ultrashort Cationic Lipo- -Peptides

(2009) G. N. Serrano et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Solution NMR studies of amphibian antimicrobial peptides: Linking structure to function?

(2009) Evan F. Haney et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Antimicrobial-Resistant Pathogens in Intensive Care Units in Canada: Results of the Canadian National Intensive Care Unit (CAN-ICU) Study, 2005-2006

(2008) G. G. Zhanel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antimicrobial Lipopolypeptides Composed of Palmitoyl Di- and Tricationic Peptides:In Vitroandin VivoActivities, Self-Assembly to Nanostructures, and a Plausible Mode of Action†

(2008) Arik Makovitzki et al.   BIOCHEMISTRY