GABA is an effective immunomodulatory molecule

 -Aminobutyric Acid Transporter 1 Negatively Regulates T Cell-Mediated Immune Responses and Ameliorates Autoimmune Inflammation in the CNS

(2014) Y. Wang et al.   JOURNAL OF IMMUNOLOGY

Oral GABA treatment downregulates inflammatory responses in a mouse model of rheumatoid arthritis

(2011) Jide Tian et al.   AUTOIMMUNITY

The immature brain needs GABA to be excited and hyper-excited

(2011) Enrico Cherubini et al.   JOURNAL OF PHYSIOLOGY-LONDON

Insulin Reduces Neuronal Excitability by Turning on GABAA Channels that Generate Tonic Current

(2011) Zhe Jin et al.   PLoS One

Anaesthetic Impairment of Immune Function Is Mediated via GABAA Receptors

(2011) Daniel W. Wheeler et al.   PLoS One

Oral Treatment with γ-Aminobutyric Acid Improves Glucose Tolerance and Insulin Sensitivity by Inhibiting Inflammation in High Fat Diet-Fed Mice

(2011) Jide Tian et al.   PLoS One

GABA exerts protective and regenerative effects on islet beta cells and reverses diabetes

(2011) N. Soltani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GABA and GABAA receptor expression on immune cells in psoriasis: a pathophysiological role

(2010) Rishi Nigam et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Anti-inflammatory effects of the GABAB receptor agonist baclofen in allergic contact dermatitis

(2010) Beatrice Duthey et al.   EXPERIMENTAL DERMATOLOGY

Increased GABAA channel subunits expression in CD8+ but not in CD4+ T cells in BB rats developing diabetes compared to their congenic littermates

(2010) Suresh Kumar Mendu et al.   MOLECULAR IMMUNOLOGY

Systemic inflammatory cells fight off neurodegenerative disease

(2010) Michal Schwartz et al.   Nature Reviews Neurology

An intrinsic GABAergic system in human lymphocytes

(2010) Leonardo Dionisio et al.   NEUROPHARMACOLOGY

Inhibitory role for GABA in autoimmune inflammation

(2010) R. Bhat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuronal activity in vitro and the in vivo reality: the role of energy homeostasis

(2010) Yuri Zilberter et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Propofol inhibits pressure-stimulated macrophage phagocytosis via the GABAA receptor and dysregulation of p130cas phosphorylation

(2009) Hiroe Shiratsuchi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

 -Aminobutyric Acid Transporter 1 Negatively Regulates T Cell Activation and Survival through Protein Kinase C-Dependent Signaling Pathways

(2009) Y. Wang et al.   JOURNAL OF IMMUNOLOGY

A novel mechanism for GABA synthesis and packaging into synaptic vesicles

(2009) Chandana Buddhala et al.   NEUROCHEMISTRY INTERNATIONAL

Cation-Chloride Cotransporters and Neuronal Function

(2009) Peter Blaesse et al.   NEURON

Innate and Adaptive Autoimmunity Directed to the Central Nervous System

(2009) Roopa Bhat et al.   NEURON

The role of cytokines in the pathophysiology of epilepsy

(2008) Annamaria Vezzani et al.   BRAIN BEHAVIOR AND IMMUNITY

Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes

(2008) Matej Orešič et al.   JOURNAL OF EXPERIMENTAL MEDICINE

GABA, a natural immunomodulator of T lymphocytes

(2008) Helen Bjurstöm et al.   JOURNAL OF NEUROIMMUNOLOGY

Does gamma-aminobutyric acid (GABA) influence the development of chronic inflammation in rheumatoid arthritis?

(2008) James M Kelley et al.   Journal of Neuroinflammation

Can the immune system be harnessed to repair the CNS?

(2008) Phillip G. Popovich et al.   NATURE REVIEWS NEUROSCIENCE

GABAA receptors: Subtypes provide diversity of function and pharmacology

(2008) Richard W. Olsen et al.   NEUROPHARMACOLOGY