Article
Psychology, Biological
Noriyuki Miyata, Tomokazu Hata, Shu Takakura, Kazufumi Yoshihara, Chihiro Morita, Katsunaka Mikami, Koji Nomoto, Kouji Miyazaki, Hirokazu Tsuji, Nobuyuki Sudo
Summary: The study compared the serum metabolic profiles of female patients with restricting type anorexia nervosa (ANR) to healthy female controls, revealing lower amino acid levels and higher uremic toxins levels in the patients. Serum PCS levels were positively correlated with specific gut microbes in ANR patients. These findings suggest a potential role of gut microbes in the increased uremic toxins levels in ANR patients.
PHYSIOLOGY & BEHAVIOR
(2021)
Article
Agriculture, Dairy & Animal Science
C. W. Maynard, S. Y. Liu, J. T. Lee, J. Caldas, J. J. E. Diehl, S. J. Rochell, S. Dridi, M. T. Kidd
Summary: This study investigated the dietary valine requirements for female broilers through three experiments, with a conclusion that the requirement is 78 Val/Lys for males and 77 Val/Lys for females based on feed conversion responses. No significant linear or quadratic responses were found in experiments 1 through 3, while some responses were observed in experiments 4 and 5, suggesting a potential need for further investigation.
ANIMAL FEED SCIENCE AND TECHNOLOGY
(2021)
Editorial Material
Psychology, Clinical
Scott J. Crow
Summary: In this issue of International Journal of Eating Disorders, Walsh et al. review the research comparing atypical anorexia nervosa (atypical AN) and AN. Most differences observed were related to weight, while psychopathology and complications were similar. The findings suggest that atypical AN and AN are not fundamentally different, emphasizing the need for further research. The high prevalence of atypical AN in clinical settings highlights the importance of continuing research.
INTERNATIONAL JOURNAL OF EATING DISORDERS
(2023)
Article
Nutrition & Dietetics
Katarzyna Jowik, Monika Dmitrzak-Weglarz, Natalia Pytlinska, Anna Jasinska-Mikolajczyk, Agnieszka Slopien, Marta Tyszkiewicz-Nwafor
Summary: This study evaluated the plasma levels of APE-13 and ASP, as well as related metabolic and psychometric parameters, in patients with anorexia nervosa. The findings suggest that APE-13 and ASP may serve as biomarkers for anorexia nervosa, and their levels are associated with eating behavior, emotional behavior, and the severity of psychopathological symptoms of eating disorders.
Editorial Material
Medicine, General & Internal
Daniel O'Meara, Lea Sheward, Sydney Hartman-Munick, Jessica Addison, Aya Abu-El-Haija
Summary: This passage describes a 17-year-old girl with a history of anxiety and anorexia nervosa who presented with a range of physical discomfort symptoms and was found to have multiple electrolyte imbalances.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Article
Nutrition & Dietetics
Heather M. McDonald, Tony Lin, Lulu L. C. D. Bursztyn
Summary: A young woman presented with significant weight loss and malnutrition due to decreased food intake, initially diagnosed with ARFID but later found to have a suprasellar and pineal germinoma. While there have been cases of germinomas misdiagnosed as anorexia nervosa, this is the first reported case of a multifocal germinoma presenting as ARFID. The criteria for diagnosing ARFID do not include body image distortion, potentially leading to misdiagnosis.
EUROPEAN JOURNAL OF CLINICAL NUTRITION
(2022)
Review
Medicine, General & Internal
Leah Puckett, Daniela Grayeb, Vishnupriya Khatri, Kamila Cass, Philip Mehler
Summary: Anorexia nervosa is a complex and deadly psychiatric disorder characterized by co-occurring psychiatric diseases and physiological changes affecting various organ systems. Early recognition and treatment are crucial to prevent serious consequences for patients.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Cell Biology
Yuji Shiozaki, Shinobu Miyazaki-Anzai, Audrey L. Keenan, Makoto Miyazaki
Summary: Amino acid deficiency can mimic starvation to induce FAM134B2 expression, with MEF2D and NR4A1 identified as critical transcription factors involved. Integrated signal response and mTOR signals do not contribute to the induction of FAM134B2 under amino acid deficiency.
Article
Environmental Sciences
Ying Liu, Yi-Rong Liu, Ya-Juan Feng, Teng Huang, Shuai Jiang, Zi-Hang Wang, Hui Cao, Wei Huang
Summary: New Particle Formation (NPF) is a crucial source of aerosol particles and has significant impacts on the environment and human health. Recent field detections have shown the presence of valine (VAL) in urban areas, suggesting its potential role in atmospheric nucleation. However, there is still a lack of comprehensive reports on how VAL interacts with precursor Sulfuric Acid (SA) and atmospheric organic amine Dimethylamine (DMA) in multi-component nucleation. This paper uses quantum chemical calculation and cluster kinetic simulation to investigate the nucleation mechanism of (SA)x(DMA)y(VAL)z (0
ATMOSPHERIC ENVIRONMENT
(2021)
Article
Medicine, General & Internal
Gregory L. Hundemer, Anna Clarke, Ayub Akbari, Ann Bugeja, David Massicotte-Azarniouch, Greg Knoll, Daniel T. Myran, Peter Tanuseputro, Manish M. Sood
Summary: In this case-control study, individuals with eating disorders were more likely to have outpatient electrolyte abnormalities compared to matched controls. Unexplained electrolyte abnormalities may serve as markers for potential underlying eating disorders, indicating the need for screening.
Article
Nutrition & Dietetics
Alessio Maria Monteleone, Jacopo Troisi, Gloria Serena, Alessio Fasano, Riccardo Dalle Grave, Giammarco Cascino, Francesca Marciello, Simona Calugi, Giovanni Scala, Giulio Corrivetti, Palmiero Monteleone
Summary: Alterations in the gut microbiome and fecal metabolites were found in anorexia nervosa (AN), with differences seen between those with restricting AN (ANR) and binge-purging AN (ANBP) types. ANBP patients showed significant differences in microbial abundances and metabolites compared to ANR patients. Despite small sample size, this study confirms the occurrence of distinct gut dysbiosis in ANR and ANBP, showcasing different connections between gut microorganisms and fecal metabolites in the two AN types.
Article
Psychology, Clinical
Neville H. Golden, Cynthia J. Kapphahn, Jing Cheng, Anna Kreiter, Amanda E. Downey, Erin C. Accurso, Vanessa I. Machen, Sally H. Adams, Sara M. Buckelew, Anna-Barbara Moscicki, Daniel Le Grange, Andrea K. Garber
Summary: The study compared the recovery outcomes of individuals with atypical anorexia nervosa (atypical AN) and anorexia nervosa (AN) after one year. It found that those with atypical AN had slower weight gain and remained further from their pre-illness weight. There were no significant differences in psychological recovery, resumption of menses, or rehospitalization rates between the two groups. The findings highlight the limited understanding of recovery in atypical AN and the need for new recovery assessment metrics.
INTERNATIONAL JOURNAL OF EATING DISORDERS
(2023)
Article
Health Care Sciences & Services
Corinna Jacobi, Bianka Vollert, Kristian Huetter, Paula von Bloh, Nadine Eiterich, Dennis Goerlich, C. Barr Taylor
Summary: This study aimed to assess the efficacy of a web-based prevention program for women at risk for anorexia nervosa (AN). The results showed promising reductions in risk factors and symptoms of AN, suggesting the potential for preventing the onset of full-syndrome AN.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Medicine, General & Internal
Ryo Koda, Satoru Miyazaki, Noriaki Iino, Yo Sato, Kenichiro Hirano, Eiji Sunami, Shinichi Kosugi, Tsutomu Kanefuji, Akira Ogose, Ichiei Narita
Summary: In the case mentioned above, a 48-year-old woman with a long history of anorexia nervosa developed osteomalacia as a complication. In addition to poor nutritional intake and inadequate sun exposure, postoperative malabsorption and kidney phosphate loss contributed to the progression of the disease.
Article
Biophysics
Da-xia Zhang, Rui Wang, Haichao Cao, Jian Luo, Tong-fang Jing, Bei-xing Li, Wei Mu, Feng Liu, Youming Hou
Summary: A study was conducted to synthesize an ecofriendly polymer for nanogel delivery system of pesticide, which showed favorable stability and efficient pest control under various conditions. The nanogel demonstrated prolonged pest control period and effective bioactivity against pests, indicating a promising future for pesticide delivery.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Cardiac & Cardiovascular Systems
Shujiro Fujita, Utako Yokoyama, Ryo Ishiwata, Rika Aoki, Kenji Nagao, Daiki Masukawa, Masanari Umemura, Takayuki Fujita, Shiho Iwasaki, Shigeru Nishimaki, Kazuo Seki, Shuichi Ito, Yoshio Goshima, Toshihide Asou, Munetaka Masuda, Yoshihiro Ishikawa
CIRCULATION JOURNAL
(2016)
Review
Endocrinology & Metabolism
Kenji Nagao, Minoru Yamakado
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
(2016)
Article
Multidisciplinary Sciences
Minoru Yamakado, Takayuki Tanaka, Kenji Nagao, Akira Imaizumi, Michiharu Komatsu, Takashi Daimon, Hiroshi Miyano, Mizuki Tani, Akiko Toda, Hiroshi Yamamoto, Katsuhisa Horimoto, Yuko Ishizaka
SCIENTIFIC REPORTS
(2017)
Article
Cell Biology
Shohei Yoshida, Kosuke Yamahara, Shinji Kume, Daisuke Koya, Mako Yasuda-Yamahara, Naoko Takeda, Norihisa Osawa, Masami Chin-Kanasaki, Yusuke Adachi, Kenji Nagao, Hiroshi Maegawa, Shin-ichi Araki
Article
Biochemistry & Molecular Biology
Jinpeng Li, Megumi Kanasaki, Ling Xu, Munehiro Kitada, Kenji Nagao, Yusuke Adachi, Hiroko Jinzu, Yasushi Noguchi, Miyuki Kohno, Keizo Kanasaki, Daisuke Koya
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
(2018)
Article
Geriatrics & Gerontology
Yusuke Adachi, Nobukazu Ono, Akira Imaizumi, Takahiko Muramatsu, Toshihiko Andou, Yoshiki Shimodaira, Kenji Nagao, Yoko Kageyama, Maiko Mori, Yasushi Noguchi, Naotaka Hashizume, Hitoshi Nukada
INTERNATIONAL JOURNAL OF GERONTOLOGY
(2018)
Article
Nutrition & Dietetics
Ikuko Sasahara, Akiko Yamamoto, Masamichi Takeshita, Yasuyo Suga, Katsuya Suzuki, Natsumi Nishikata, Michihiro Takada, Masaki Hashimoto, Tomoyuki Mine, Yasuo Kobuna, Kenji Nagao
JOURNAL OF NUTRITION
(2020)
Article
Nutrition & Dietetics
Kenji Nagao, Takeshi Kimura
Article
Nutrition & Dietetics
Hiroyuki Suzuki, Daichi Yamashiro, Susumu Ogawa, Momoko Kobayashi, Daisuke Cho, Ai Iizuka, Masako Tsukamoto-Yasui, Michihiro Takada, Muneki Isokawa, Kenji Nagao, Yoshinori Fujiwara
FRONTIERS IN NUTRITION
(2020)
Article
Neurosciences
Fumika Takeuchi, Natsumi Nishikata, Mai Nishimura, Kenji Nagao, Masahito Kawamura
Summary: In this study, a modified ketogenic diet enriched with leucine was developed to enhance the antiseizure effects, indicating a potential new therapeutic option for patients with epilepsy.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Nutrition & Dietetics
Takeshi Ikeuchi, Yuki Yano, Wataru Sato, Fumiyoshi Morikawa, Shuta Toru, Chika Nishimura, Nobuhiko Miyazawa, Yasuko Kuroha, Ryoko Koike, Shin Tanaka, Kumiko Utsumi, Kensaku Kasuga, Takayoshi Tokutake, Kenjiro Ono, Satoshi Yano, Satoshi Naruse, Ryuji Yajima, Tadanori Hamano, Yuri Yokoyama, Akihiko Kitamura, Eiji Kaneko, Minoru Yamakado, Kenji Nagao
Summary: Nutritional epidemiology has emphasized the importance of protein intake in maintaining brain function in the elderly population. This multicenter study explored the association between protein nutritional status and mild cognitive impairment (MCI) using blood-based biomarkers. The results revealed significantly lower concentrations of certain essential amino acids and albumin in the MCI group compared to the cognitively normal (CN) group. The model incorporating albumin and PFAAs successfully discriminated MCI from CN participants.
Article
Multidisciplinary Sciences
Hideaki Sato, Yuhei Takado, Sakiko Toyoda, Masako Tsukamoto-Yasui, Keiichiro Minatohara, Hiroyuki Takuwa, Takuya Urushihata, Manami Takahashi, Masafumi Shimojo, Maiko Ono, Jun Maeda, Asumi Orihara, Naruhiko Sahara, Ichio Aoki, Sachise Karakawa, Muneki Isokawa, Noriko Kawasaki, Mika Kawasaki, Satoko Ueno, Mayuka Kanda, Mai Nishimura, Katsuya Suzuki, Akira Mitsui, Kenji Nagao, Akihiko Kitamura, Makoto Higuchi
Summary: The study suggests that a low-protein diet may accelerate brain atrophy in a neurodegenerative disease model in mice, and this abnormal phenotype can be robustly rescued by administration of seven selected essential amino acids. These essential amino acids can also suppress the up-regulation of inflammation-associated gene expression and progressive brain atrophy.
Article
Nutrition & Dietetics
Yasuyuki Kitaura, Kohsuke Hayamizu, Eri Wada, Boryana Petrova, Kenji Nagao
Summary: This review summarizes some recent discoveries of unexpected amino acid functions, especially in BCAAs, histidine and serine.
JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY
(2022)
Article
Nutrition & Dietetics
Takeshi Ikeuchi, Mayuka Kanda, Hitomi Kitamura, Fumiyoshi Morikawa, Shuta Toru, Chika Nishimura, Kensaku Kasuga, Takayoshi Tokutake, Tetsuya Takahashi, Yasuko Kuroha, Nobuhiko Miyazawa, Shin Tanaka, Kumiko Utsumi, Kenjiro Ono, Satoshi Yano, Tadanori Hamano, Satoshi Naruse, Ryuji Yajima, Noriko Kawashima, Chikako Kaneko, Hisatsugu Tachibana, Yuki Yano, Yumiko Kato, Sakino Toue, Hiroko Jinzu, Akihiko Kitamura, Yuri Yokoyama, Eiji Kaneko, Minoru Yamakado, Kenji Nagao
Summary: The study found that certain amino acids in the plasma are associated with the development of AD in MCI participants, especially in the APOE epsilon4-negative population. This suggests that the plasma free amino acid profile can serve as an independent indicator for assessing the risk of AD development in the MCI population.
FRONTIERS IN NUTRITION
(2022)
Article
Nutrition & Dietetics
Hideaki Sato, Masako Tsukamoto-Yasui, Yuhei Takado, Noriko Kawasaki, Keiko Matsunaga, Satoko Ueno, Mayuka Kanda, Mai Nishimura, Sachise Karakawa, Muneki Isokawa, Katsuya Suzuki, Kenji Nagao, Makoto Higuchi, Akihiko Kitamura
FRONTIERS IN NUTRITION
(2020)