Article
Immunology
Kristien Cloots, Pia Marino, Sakib Burza, Naresh Gill, Marleen Boelaert, Epco Hasker
Summary: The study found that VL-HIV+ and PKDL cases were both associated with a more than twofold increase in VL incidence at the village level in Bihar, India, indicating the importance of VL-HIV+ patients as infectious reservoirs for Leishmania.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Infectious Diseases
Vidya Nand Rabi Das, Niyamat Ali Siddiqui, Gouri Sankar Bhunia, Krishna Pandey, Sanjay Kumar Sinha, Md Zahid Ansari, Roshan Kamal Topno, Chandra Sekhar Lal, Alok Ranjan, Vijay Pratap Singh, Pradeep Das
Summary: The establishment and activation of kala-azar sentinel site surveillance in thirteen health facilities of Bihar from 2011 to 2014 detected a rise in PKDL and co-infections. The results showed significant improvement in utilization of laboratory services and case management, with most patients being managed by the sentinel sites. The system may provide a model for improving elimination interventions and program management.
PLOS NEGLECTED TROPICAL DISEASES
(2021)
Article
Environmental Sciences
Arun Kumar, Rishav Kumar, Md Samiur Rahman, Mohammad Ali, Ranjit Kumar, Neha Nupur, Aman Gaurav, Vikram Raj, Gautam Anand, Pintoo Kumar Niraj, Nirmal Kumar, Abhinav Srivastava, Akhouri Biswapriya, Gyanendra Bahadur Chand, Dhruv Kumar, Tuhin Rashmi, Santosh Kumar, Maiko Sakamoto, Ashok Kumar Ghosh
Summary: Arsenic poisoning through groundwater is a major global catastrophe, with significant impact on public health. A study conducted in a village in Bihar, India, revealed high levels of arsenic exposure leading to various health issues and cancer cases among the population. The installation of an arsenic filter plant in the village aims to improve the health situation in the future.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Public, Environmental & Occupational Health
J. S. Devipriya, Ashok Kumar Gupta, Garapati Pavan, Sameer Dhingra, Krishna Murti, Velayutham Ravichandiran, Krishna Pandey
Summary: This study assessed the knowledge, attitude, and practices (KAP) toward VL infection among VL-infected and HIV/VL co-infected patients in Bihar. The findings showed similar deficits in KAP scores among both groups. HIV/VL participants with a personal or family history of VL had better awareness and preventive practices. There was a correlation between knowledge, attitude, and practice. It is recommended to strengthen KAP among VL and HIV/VL co-infected patients to prevent reinfection-related complications.
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
(2022)
Article
Parasitology
Khushbu Priyamvada, Joy Bindroo, Madan Prashad Sharma, Lloyd A. C. Chapman, Pushkar Dubey, Tanmay Mahapatra, Allen W. Hightower, Caryn Bern, Sridhar Srikantiah
Summary: This study highlights the importance of sensitive surveillance for early detection and response to visceral leishmaniasis outbreaks. High risk groups identified include individuals aged 10 and above, as well as residents of SC/ST tolas. Efforts should focus on enhancing surveillance in these disadvantaged communities to better control transmission.
PARASITES & VECTORS
(2021)
Article
Public, Environmental & Occupational Health
Santhi John Tharakan, Dincy C. Peter, Rajiv Karthik, Vedantam Rupa, Winsley Rose, Meera Thomas, Malathi Manuel, Priscilla Rupali, Susanne Pulimood, Sitara Swarna Rao Ajjampur
Summary: This study reports on 52 suspected cases of cutaneous and mucosal leishmaniasis in a tertiary care setting in southern India from 2008 to 2018. Of the 12 confirmed cases, seven had mucocutaneous leishmaniasis, two had cutaneous leishmaniasis, and three had post-kala-azar dermal leishmaniasis. The emerging trend of atypical MCL caused by L. donovani variants highlights the importance of a high index of suspicion combined with PCR-based diagnostics for accurate diagnosis of different manifestations of leishmaniasis.
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
(2021)
Article
Immunology
Luc E. Coffeng, Epke A. Le Rutte, Johanna Munoz, Emily Adams, Sake J. de Vlas
Summary: After scaling down control efforts for visceral leishmaniasis (VL) on the Indian subcontinent, population-based surveys of antibody or antigenemia prevalence can be used to predict the potential recurrence of new VL cases. Biomarker prevalence, especially in adults, was found to be highly correlated with the occurrence of new VL cases within 1-2 years after scaling down. Rapid point-of-care diagnostic tools assessing seroprevalence or antigenemia in the general population could be crucial for sustainable VL control.
CLINICAL INFECTIOUS DISEASES
(2021)
Review
Parasitology
Polrat Wilairatana, Wetpisit Chanmol, Pongruj Rattaprasert, Frederick Ramirez Masangkay, Giovanni De Jesus Milanez, Kwuntida Uthaisar Kotepui, Manas Kotepui
Summary: The study systematically reviewed co-infection of malaria and visceral leishmaniasis, finding heterogeneous prevalence rates in different geographical areas. Age and anemia at admission were associated with co-infection status. Further longitudinal studies are needed to determine the impact of malaria co-infection on the severity of visceral leishmaniasis.
PARASITES & VECTORS
(2021)
Correction
Multidisciplinary Sciences
Sarfaraz Ahmad Ejazi, Sneha Ghosh, Samiran Saha, Somsubhra Thakur Choudhury, Anirban Bhattacharyya, Mitali Chatterjee, Krishna Pandey, V. N. R. Das, Pradeep Das, Mehebubar Rahaman, Rama Prosad Goswami, Keshav Rai, Basudha Khanal, Narayan Raj Bhattarai, Bhagya Deepachandi, Yamuna Deepani Siriwardana, Nadira D. Karunaweera, Maria Edileuza Felinto deBrito, Yara de Miranda Gomes, Mineo Nakazawa, Carlos Henrique Nery Costa, Emebet Adem, Arega Yeshanew, Roma Melkamu, Helina Fikre, Zewdu Hurissa, Ermias Diro, Eugenia Carrillo, Javier Moreno, Nahid Ali
Summary: An updated version of the paper has been published and can be accessed through a link at the top of the paper.
SCIENTIFIC REPORTS
(2021)
Article
Infectious Diseases
Pamornsri Sriwongpan, Supalert Nedsuwan, Jidapa Manomat, Sakarn Charoensakulchai, Kittiphat Lacharojana, Jamnong Sankwan, Natheeporn Kobpungton, Taweesak Sriwongpun, Saovanee Leelayoova, Mathirut Mungthin, Suradej Siripattanapipong, Toon Ruang-areerate, Tawee Naaglor, Theethach Eamchotchawalit, Phunlerd Piyaraj
Summary: This study is the first community-based investigation in Thailand that examines the prevalence and associated risk factors of Leishmania infection among immunocompetent individuals. It highlights the urgent need for effective interventions to prevent and control the disease in endemic areas.
PLOS NEGLECTED TROPICAL DISEASES
(2021)
Article
Immunology
Joy Bindroo, Khushbu Priyamvada, Lloyd A. C. Chapman, Tanmay Mahapatra, Bikas Sinha, Indranath Banerjee, Prabhas Kumar Mishra, Basab Rooj, Kumar Kundan, Nupur Roy, Naresh Kumar Gill, Allen Hightower, Madan Prasad Sharma, Neeraj Dhingra, Caryn Bern, Sridhar Srikantiah
Summary: India has made significant progress in controlling visceral leishmaniasis by shortening the time untreated patients remain infectious. Research shows that the risk of additional cases in villages increases with higher cumulative incidence, and the time-to-next-case decreases with increasing case-load.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Multidisciplinary Sciences
J. S. Devipriya, Ashok Kumar Gupta, Rajendra Babu Veeri, Pavan Garapati, Rishikesh Kumar, Sameer Dhingra, Krishna Murti, V. Ravichandiran, Krishna Pandey
Summary: The study found a significant gap in knowledge, attitude, and practices towards visceral leishmaniasis among people living with HIV in Bihar, highlighting the need for enhanced health education initiatives in endemic areas to improve awareness and preventive practices for VL.
Article
Immunology
Pushkar Dubey, Aritra Das, Khushbu Priyamvada, Joy Bindroo, Tanmay Mahapatra, Prabhas Kumar Mishra, Ankur Kumar, Ana O. Franco, Basab Rooj, Bikas Sinha, Sreya Pradhan, Indranath Banerjee, Manash Kumar, Nasreen Bano, Chandan Kumar, Chandan Prasad, Parna Chakraborty, Rakesh Kumar, Niraj Kumar, Aditya Kumar, Abhishek Kumar Singh, Kumar Kundan, Sunil Babu, Hemant Shah, Morchan Karthick, Nupur Roy, Naresh Kumar Gill, Shweta Dwivedi, Indrajit Chaudhuri, Allen W. Hightower, Lloyd A. C. Chapman, Chandramani Singh, Madan Prasad Sharma, Neeraj Dhingra, Caryn Bern, Sridhar Srikantiah
Summary: India is making progress towards eliminating visceral leishmaniasis as a public health problem, with timely case detection playing a crucial role in reducing infectivity and controlling outbreaks. Active case detection strategies have been shown to significantly reduce time to diagnosis, lower transmission risk, and ensure higher capture rates of confirmed cases.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Public, Environmental & Occupational Health
Shyla Faria, Sarder Mahmud Hossain, Md. Sahidul Islam, Vashkar Chowdhury, Rajib Chowdhury
Summary: This study aimed to assess the knowledge, attitudes, and practices related to kala-azar in Bangladesh, in order to provide recommendations for the national elimination program. A cross-sectional study was conducted in two endemic subdistricts, and data were collected through interviews and questionnaires. The findings showed that while most participants had heard of kala-azar, there were gaps in their understanding of its transmission and prevention methods. Additionally, the study highlighted the importance of strengthening community engagement and healthcare facilities in the national program.
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
(2023)
Article
Multidisciplinary Sciences
Shekhar Chauhan, Pradeep Kumar, Strong P. Marbaniang, Shobhit Srivastava, Ratna Patel
Summary: Anaemia in adolescents is associated with physical disorders, growth, and mental retardation, with higher prevalence among adolescent girls. This study fills a gap in anaemia intervention programs for adolescents by analyzing data from Uttar Pradesh and Bihar, India. The findings suggest that anaemia is more prevalent among rural adolescents, those with lower education levels, late adolescence, and those with no exposure to mass media. Effective public health policies targeting rural adolescents and disseminating information through mass media are needed to address anaemia in this population.
SCIENTIFIC REPORTS
(2022)
