期刊
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
卷 85, 期 3, 页码 442-445出版社
AMER SOC TROP MED & HYGIENE
DOI: 10.4269/ajtmh.2011.10-0368
关键词
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资金
- Ministry of Science and Technology of China [2008ZX10004-001]
- Young Scholar Scientific Research Foundation of China CDC [2010A105]
- State Key Laboratory for Infectious Disease Prevention and Control [2008SKLID105]
- China CDC-US CDC [U19-GH000004]
Tahyna virus (TAHV) is widely distributed in Europe and Asia. A previous study reported a high level of conservation of the TAHV genome in isolates from Europe. During 2006 and 2007, three Tahyna virus isolates from mosquitoes were obtained from various locations in Xinjiang, People's Republic of China. We analyzed the complete coding sequence of full-length small, medium, and large segments of these isolates. Molecular and phylogenetic analyses of the three complete TAHV genomes showed that sequence identity between isolates from China and Europe was more divergent, and an unexpected level of medium segment diversity was found among isolates from China compared with high levels of sequence conservation for the small and large segments. This study indicated that effects of genotypic diversity on the ecology, transmission, and pathogenicity of TAHV in China should be studied.
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