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The SYBR Green I Malaria Drug Sensitivity Assay: Performance in Low Parasitemia Samples

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AMER SOC TROP MED & HYGIENE
DOI: 10.4269/ajtmh.2010.09-0417

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Validation of the sensitivity of the SYBR Green I in vitro test against an enzyme-linked immunosorbent assay (ELISA)-based drug sensitivity assay. Our results suggest that the SYBR Green I assay is a fast and inexpensive malaria drug screening assay for laboratory use. However, because of its lack of sensitivity in whole blood samples its usefulness for testing clinical samples may be limited.

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