期刊
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
卷 82, 期 2, 页码 301-305出版社
AMER SOC TROP MED & HYGIENE
DOI: 10.4269/ajtmh.2010.09-0538
关键词
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资金
- Kelsey Research Foundation
- University of Texas School of Public Health
- Public Health Service [DK 56338]
- Texas Gulf Coast Digestive Diseases Center
- Salix Pharmaceuticals, Inc.
- McNeil Consumer Healthcare
- IOMAI Corporation
- Intercell Corporation
- Optimer Pharmaceuticals, Inc.
This Study evaluated Occurrence of travel and travelers diarrhea in patients with irritable bowel syndrome (IBS). A survey was mailed to 591 patients of a clinical practice who had IBS. Based oil survey responses, patients were categorized as having IBS, post-infectious IBS (PI-IBS), Unclassified functional bowel disorder (UFBD), or post-infectious UFBD (PI-UFBD). Of 201 Persons Who returned questionnaires meeting inclusion criteria, 57.7%, 11.4%, 24.9%, and 6.0% had IBS, UFBD, PI-IBS, and PI-UFBD, respectively. Travel during six months before illness onset was more common in patients with PI-IBS or PI-UFBD than in persons with idiopathic IBS or UFBD (P = 0.006). Survey results demonstrated that 16.1% of post-infectious bowel disorder cases and 7.5% of overall IBS cases in a general medical population developed chronic disease within six months of ail international trip. Symptoms of established functional bowel disorder in each clinical category were shown to worsen after travel-related acute diarrhea.
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