Article
Agronomy
Abdelfattah Selim, Marawan A. Marawan, Abdelhamed Abdelhady, Majed H. Wakid
Summary: A cross-sectional study conducted in Egypt found that the seroprevalence of Toxoplasma gondii in dromedary camels was 46.9%. Risk factors for T. gondii infection in camels included locality, sex, age, contact with small ruminants, history of abortion, and number of parities. Evaluating the seroprevalence and related risk factors is crucial for controlling T. gondii infection in camels and preventing transmission to humans.
Article
Agriculture, Dairy & Animal Science
Petra Bandelj, Diana Zele Vengust, Rok Blagus, Aleksandra Vergles Rataj, Branko Krt
Summary: The study revealed a high prevalence of Toxoplasma gondii in the Slovenian wild boar population at 62%, the highest reported worldwide. The prevalence increased with age and weight, but not with gender. Due to the high prevalence, handling raw or undercooked wild boar meat poses a significant risk of Toxoplasma exposure.
Article
Microbiology
Sara Caldrer, Ambra Vola, Guglielmo Ferrari, Tamara Ursini, Cristina Mazzi, Valeria Meroni, Anna Beltrame
Summary: This study investigated the epidemiological distribution of T. gondii serotypes in humans in Italy. The results showed that type II of T. gondii was most prevalent in Italians, while type I-III was most prevalent in foreigners. A significant difference in serotype prevalence was also observed between men and women, as well as between Italians and foreigners.
Article
Veterinary Sciences
Mohamed Marzok, Omar A. AL-Jabr, Mohamed Salem, Khalid Alkashif, Mohamed Sayed-Ahmed, Majed H. Wakid, Mahmoud Kandeel, Abdelfattah Selim
Summary: This study confirms that horses in Northern Egypt are exposed to Toxoplasma gondii and raises the possibility that people and other animals could contract the disease.
VETERINARY SCIENCES
(2023)
Article
Parasitology
Emilie Bouchard, Rajnish Sharma, Adrian Hernandez-Ortiz, Kayla Buhler, Batol Al-Adhami, Chunlei Su, Heather Fenton, Geraldine G.-Gouin, James D. Roth, Chloe Warret Rodrigues, Carla Pamak, Audrey Simon, Nicholas Bachand, Patrick Leighton, Emily Jenkins
Summary: This study investigated the seroprevalence and tissue infection rate of Toxoplasma gondii in foxes in northern Canada. The findings showed a higher antibody detection rate in older foxes. There was a correlation between the seroprevalence of foxes and humans in different regions of Canada.
PARASITES & VECTORS
(2022)
Article
Immunology
Min Chen, Pei Yang, Zixuan Xin, Jiating Chen, Weihao Zou, Lijuan Zhou, Lili Yang, Jiao Peng, Hongjuan Peng
Summary: Toxoplasma gondii is a pathogen causing toxoplasmosis and has similarities with immunotherapy for cancers. The knockout of GRA5 gene in T. gondii resulted in an avirulent strain that stimulated immune responses. ME49 & UDelta;gra5 vaccination provided protection against T. gondii infection and breast cancer by boosting anti-tumor responses. The vaccine upregulated Th1 cytokines and tumor-infiltrating T cells, and increased the number of immune cells in the spleen.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Veterinary Sciences
Victor Lizana, Christian Gortazar, Ana Muniesa, Oscar Cabezon, Alba Marti-Marco, Jordi Lopez-Ramon, Jesus Cardells
Summary: Toxoplasma gondii infection can be transmitted through consuming undercooked wild boar meat, which also serves as a bioindicator of the parasite's circulation in the ecosystem. In Spain, a study on 1003 wild boars found a prevalence rate of 14.1%, with variations in different regions and age groups.
RESEARCH IN VETERINARY SCIENCE
(2021)
Article
Microbiology
Dina B. Salama, Ragab M. Fereig, Hanan H. Abdelbaky, Moshera S. Shahat, Waleed M. Arafa, Shawky M. Aboelhadid, Adel E. A. Mohamed, Samy Metwally, Osama Abas, Xun Suo, Nishith Gupta, Caroline F. Frey
Summary: This study investigated the infection rates of Toxoplasma gondii and Neospora caninum in dogs and cats in Egypt. The results showed that 23.3% of dogs were exposed to T. gondii, while 5.8% had N. caninum-specific antibodies. In cats, the exposure rate to T. gondii was 9.8%, and 3.4% had N. caninum-specific antibodies. Factors such as age and breed were significantly associated with T. gondii antibody positivity in dogs.
Article
Parasitology
Reham Abdel-Halim Khattab, Safaa Mohamed Barghash, Osama Mohammad Sayed Mostafa, Sahar Ali Allam, Hoda Abdel-Halim Taha, Ameen Abd El-Baqi Ashour
Summary: The study revealed a high prevalence of Toxoplasma gondii infection in ruminants in the North-West of Egypt, especially in camels and sheep. PCR detection was found to be more accurate in identifying T. gondii in blood samples, with implications for disease control and containment of infection spread.
Article
Microbiology
Ragab M. Fereig, Hanan H. Abdelbaky, Amira M. Mazeed, El-Sayed El-Alfy, Somaya Saleh, Mosaab A. Omar, Abdullah F. Alsayeqh, Caroline F. Frey
Summary: The prevalence of antibodies to Neospora caninum and Toxoplasma gondii in raw milk samples from different ruminants and Egyptian governorates was estimated. The study found a seroprevalence of 15.4% for both N. caninum and T. gondii antibodies in bulk milk samples, and 25.7% and 14% for individual milk samples, respectively. The presence of DNA was also detected for both parasites. Pearson correlation analysis showed a strong correlation between bulk and individual samples for T. gondii and a moderately strong correlation for N. caninum.
Article
Multidisciplinary Sciences
Iti Saraav, Luisa Cervantes-Barragan, Philipp Olias, Yong Fu, Qiuling Wang, Leran Wang, Yi Wang, Matthias Mack, Megan T. Baldridge, Thaddeus Stappenbeck, Marco Colonna, L. David Sibley
Summary: Oral infection with Toxoplasma gondii exacerbates damage to the colon caused by chemical irritant and impairs wound healing by suppressing stem cell regeneration. Enhanced tissue damage is due to inflammatory monocytes releasing inflammatory mediators.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Microbiology
Guojing Li, Wangli Zheng, Jinfang Yang, Tongsheng Qi, Yongcai He, Wangkai Chen, Hejia Ma, Yali Sun, Ying Li, Ming Kang, Jixu Li
Summary: This study conducted in the Qinghai-Tibetan Plateau Area revealed a high seroprevalence of Toxoplasma gondii infections among various animal species in the region, particularly in pigs and Tibetan sheep.
Review
Parasitology
Rajshekhar Y. Gaji, Amanda K. Sharp, Anne M. Brown
Summary: Toxoplasma gondii is a life-threatening intracellular pathogen that depends on protein kinases for its life cycle. Research on Toxoplasma kinases aims to understand their functions and potentially develop therapeutics against this parasite.
INTERNATIONAL JOURNAL FOR PARASITOLOGY
(2021)
Article
Parasitology
Yongle Song, Yongjuan Zhao, Ke Pan, Bang Shen, Rui Fang, Min Hu, Junlong Zhao, Yanqin Zhou
Summary: A novel diagnostic marker, MAG antigen, was designed for accurate and sensitive detection of anti-T. gondii IgG in pigs using MAG-ELISA method. This method has the potential for large-scale screening of T. gondii infection in pig farms and intensive industries.
PARASITES & VECTORS
(2021)
Article
Immunology
Xiaomei Liu, Li Fan, Qianqian Tan, Xiao Chen, Hongmei Li, Xiaomin Zhao, Xiao Zhang
Summary: This study developed an ELISA method using SAG1 to investigate the seroprevalence of Toxoplasma gondii in pigs in Shandong province, China. The results showed significant differences in infection rates among different regions and populations, with the highest seroprevalence observed in gestating sows.
COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES
(2022)