Article
Medicine, General & Internal
Kavita Khoiwal, Nirali Kapoor, Amrita Gaurav, Om Kumari, Jaya Chaturvedi
Summary: This study compared the efficacy and safety of unidirectional barbed suture with conventional polyglactin 910 suture for vaginal cuff closure in patients undergoing total laparoscopic hysterectomy. The results showed that the unidirectional barbed suture significantly reduces vaginal cuff closure time and is a safe, effective alternative.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2021)
Article
Multidisciplinary Sciences
Wael Mbarki, Hajer Bettaieb, Nesrine Souayeh, Idriss Laabidi, Hadhemi Rouis, Soumaya Halouani, Rami Boufarghine, Maha Bouyahia, Rahma Bouhmida, Mariem Ouederni, Anissa Ben Amor, Amal Chermiti, Hadir Laamiri, Amira Lika, Imen Chaibi, Hedhili Oueslati, Najeh Hsayaoui, Chaouki Mbarki
Summary: The objective of this study was to assess the effectiveness of Triclosan coated suture in reducing surgical site infections (SSIs) rate and wound healing complications after caesarian delivery. The results showed that the use of Triclosan coated suture was associated with a 69% reduction in SSI rate and a statistically lower risk of wound healing complications.
Article
Surgery
Yoko Takayama, Toshiaki Komatsu, Takatoshi Nakamura, Yoshinori Tomoda, Masaya Toda, Hirohisa Miura, Takeo Sato, Koichiro Atsuda, Hirotsugu Okamoto, Hideaki Hanaki
Summary: This study aimed to investigate the association between antibiotic concentrations and the incidence of surgical site infections in colorectal surgery cases. The results showed that low cefmetazole concentrations in subcutaneous fat tissue were found to be a significant risk factor for surgical site infections.
Article
Orthopedics
Peiliang He, Ziting Liu, Huan Chen, Guowei Huang, Wei Mao, Aiguo Li
Summary: This meta-analysis aimed to compare the effects of triclosan-coated and uncoated sutures on surgical site infection (SSI) after hip and knee arthroplasty. Three randomized-controlled studies (RCTs) with a total of 2,689 cases were included. The results showed that the incidence of SSI was not significantly different between the triclosan-coated suture group and the control group.
JOINT DISEASES AND RELATED SURGERY
(2023)
Article
Green & Sustainable Science & Technology
Yue Zhang, Ting-Ting Li, Bing-Chiuan Shiu, Fei Sun, Hai-Tao Ren, Xuefei Zhang, Ching-Wen Lou, Jia-Horng Lin
Summary: The study prepared PLA/TPU/triclosan nonwovens with improved waterproof, antimicrobial, mechanical, and abrasion resistant performance through needle punch-pad-coat method. The modified nonwovens showed excellent water repellency, modest breathability, robust tensile strength, and good antimicrobial performance against Staphylococcus aureus and Escherichia coli, making them significant for the design of low cost, eco-friendly, sustainable, and mass production of medical products.
JOURNAL OF CLEANER PRODUCTION
(2021)
Article
Surgery
Yoshitaka Terada, Toru Miyake, Tomoyuki Ueki, Tomoharu Shimizu, Masatsugu Kojima, Katsushi Takebayashi, Hiromitsu Maehira, Sachiko Kaida, Tsuyoshi Yamaguchi, Hiroya Iida, Masaji Tani
Summary: An observational cohort study on 318 consecutive patients undergoing elective colorectal cancer surgery found that there was no significant difference in the incidence of incisional SSIs between different types of triclosan-coated sutures, with the presence of stoma being the only independent risk factor for incisional SSIs.
Article
Surgery
Ingrid Woelfel, Anand Gupta, Savannah Renshaw, Benjamin Poulose
Summary: A retrospective study found no significant impact of previous solid organ transplantation history on post-operative length of stay and surgical site complications in elective ventral hernia repairs.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Pharmacology & Pharmacy
S. Chaganti, V. Kunthsam, S. Y. Velangini, K. J. Alzahrani, F. M. Alzahrani, I. F. Halawani, M. Alshahrani, H. Ashi, H. A. Baeshen, S. Patil
Summary: The oral cavity is a significant reservoir for bacteria, and tissue healing is compromised after flap surgery due to bacterial accumulation. This study found that antibacterial-coated sutures can reduce bacterial growth and improve tissue healing after flap surgery.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2023)
Article
Pharmacology & Pharmacy
Prasanna Vippadapu, Syed Wasif Gillani, Dixon Thomas, Fiaz Ahmed, Shabaz Mohiuddin Gulam, Rana Kamran Mahmood, Vineetha Menon, Semira Abdi, Hassaan Anwer Rathore
Summary: This study aimed to investigate the choice of Surgical Antimicrobial Prophylaxis at a tertiary-level care hospital in the United Arab Emirates. The study found that there was overuse of antimicrobials in surgical antibiotic prophylaxis, with ceftriaxone being preferred over cefuroxime in all types of surgeries. No surgical site infections were reported. The study recommends a follow-up comparative study to reduce antimicrobial use without increasing the risk of surgical site infection.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Surgery
Luke M. Stewart, Emily L. Spangler, Danielle C. Sutzko, Benjamin J. Pearce, Graeme E. McFarland, Marc A. Passman, Mark A. Patterson, Brent Haverstock, Kenneth Unger, Zdenek Novak, Adam W. Beck
Summary: This study investigated the impact of preoperative length of stay (LOS) on surgical site infection (SSI) in patients with chronic limb-threatening ischemia undergoing lower extremity bypass (LEB). Results showed that a longer preoperative LOS was associated with an increased rate of SSI, along with factors such as blood transfusion and longer procedure length.
JOURNAL OF VASCULAR SURGERY
(2021)
Article
Surgery
Norikatsu Miyoshi, Shiki Fujino, Junichi Nishimura, Yozo Suzuki, Masami Ueda, Mamoru Uemura, Matkoto Fujii, Kohei Murata, Yuichiro Doki, Hidekazu Eguchi
Summary: This study evaluated the effectiveness of triclosan-coated sutures in preventing surgical site infections (SSIs) after abdominal fascia closure. The results showed that triclosan-coated sutures significantly reduced the incidence of SSIs compared to uncoated sutures. This study has important clinical implications for reducing infection risks after elective colorectal cancer surgery.
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
(2022)
Article
Surgery
Jeremy M. Adkins, Roy Al Ahmar, Hongwei D. Yu, Shane T. Musick, Anthony M. Alberico
Summary: The study demonstrated that soaking sutures in bacitracin irrigation solution can effectively inhibit the growth of Staphylococcus aureus and Methicillin-resistant Staphylococcus aureus, with significantly larger zones of inhibition compared to unsoaked control sutures. While commercially available antimicrobial sutures and bacitracin aliquots showed better inhibition effects, placing sutures in antibiotic irrigation solution during surgery can achieve some in vitro antimicrobial activity.
JOURNAL OF SURGICAL RESEARCH
(2022)
Review
Medicine, General & Internal
Jessica L. Seidelman, Christopher R. Mantyh, Deverick J. Anderson
Summary: Surgical site infections occur in 0.5% to 3% of patients undergoing surgery and are associated with longer hospital stays. Measures such as avoiding razors, maintaining normothermia, using chlorhexidine gluconate plus alcohol-based skin preparation, decolonization with intranasal antistaphylococcal agents, controlling perioperative glucose concentrations, and using negative pressure wound therapy can reduce the rate of surgical site infections.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2023)
Article
Pharmacology & Pharmacy
Sunitha Sampathi, Pankaj Kumar Tiriya, Sujatha Dodoala, Vijayabhaskarreddy Junnuthula, Sathish Dyawanapelly
Summary: This study developed ciprofloxacin hydrochloride-loaded gold nanoparticles and coated them onto sterile surgical sutures using an adsorption technique followed by ionotropic crosslinking. The drug-coupled nanoparticle-laden sutures showed enhanced antibacterial properties and prolonged drug release, indicating their potential as a clinical option for preventing surgical site infections.
Review
Microbiology
Frederic C. Daoud, Maider Coppry, Nicholas Moore, Anne-Marie Rogues
Summary: RCTs show a lower incidence rate of SSIs with triclosan sutures compared with non-triclosan sutures, but no significant difference in microbial diversity of culture-confirmed SSIs was found. The pooled RR of ccSSIs was significant, but the statistical power was low for testing the association between TS antimicrobial activity and reduced SSIs.
