Targeting Interleukin-13 with Tralokinumab Attenuates Lung Fibrosis and Epithelial Damage in a Humanized SCID Idiopathic Pulmonary Fibrosis Model

Periostin, a Matricellular Protein, Plays a Role in the Induction of Chemokines in Pulmonary Fibrosis

(2012) Masaru Uchida et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

A phase II placebo-controlled study of tralokinumab in moderate-to-severe asthma

(2012) Edward Piper et al.   EUROPEAN RESPIRATORY JOURNAL

Prostaglandin E2and the Pathogenesis of Pulmonary Fibrosis

(2011) Paul D. Bozyk et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Preclinical development of CAT-354, an IL-13 neutralizing antibody, for the treatment of severe uncontrolled asthma

(2011) RD May et al.   BRITISH JOURNAL OF PHARMACOLOGY

Lebrikizumab Treatment in Adults with Asthma

(2011) Jonathan Corren et al.   NEW ENGLAND JOURNAL OF MEDICINE

Diminished Prostaglandin E2Contributes to the Apoptosis Paradox in Idiopathic Pulmonary Fibrosis

(2010) Toby M. Maher et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

An open-label, single-dose bioavailability study of the pharmacokinetics of CAT-354 after subcutaneous and intravenous administration in healthy males

(2010) Chad K. Oh et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Periostin, a matrix protein, is a novel biomarker for idiopathic interstitial pneumonias

(2010) M. Okamoto et al.   EUROPEAN RESPIRATORY JOURNAL

TLR9 Differentiates Rapidly from Slowly Progressing Forms of Idiopathic Pulmonary Fibrosis

(2010) G. Trujillo et al.   Science Translational Medicine

Gelsolin Regulates Cardiac Remodeling After Myocardial Infarction Through DNase I–Mediated Apoptosis

(2009) Guo Hua Li et al.   CIRCULATION RESEARCH

Interleukin-13 and Its Receptors in Idiopathic Interstitial Pneumonia: Clinical Implications for Lung Function

(2009) Sung-Woo Park et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

Pulmonary fibrosis: pathogenesis, etiology and regulation

(2009) M S Wilson et al.   Mucosal Immunology

IL-13 as a therapeutic target for respiratory disease

(2008) Marion T. Kasaian et al.   BIOCHEMICAL PHARMACOLOGY

Standardized quantification of pulmonary fibrosis in histological samples

(2008) Ralf-Harto Hübner et al.   BIOTECHNIQUES

IL-13 Attenuates Vascular Tube Formation Via JAK2-STAT6 Pathway

(2008) Yuki Nishimura et al.   CIRCULATION JOURNAL

Hyper-responsiveness of IPF/UIP fibroblasts: Interplay between TGFβ1, IL-13 and CCL2

(2008) Lynne A. Murray et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY