Inhibition of Overactive Transforming Growth Factor–β Signaling by Prostacyclin Analogs in Pulmonary Arterial Hypertension

BMP type II receptor deficiency confers resistance to growth inhibition by TGF-β in pulmonary artery smooth muscle cells: role of proinflammatory cytokines

(2012) Rachel J. Davies et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

BMPR-II deficiency elicits pro-proliferative and anti-apoptotic responses through the activation of TGFβ-TAK1-MAPK pathways in PAH

(2012) Md Talat Nasim et al.   HUMAN MOLECULAR GENETICS

cAMP Phosphodiesterase Inhibitors Increases Nitric Oxide Production by Modulating Dimethylarginine Dimethylaminohydrolases

(2011) Soni Savai Pullamsetti et al.   CIRCULATION

Smooth Muscle Proliferation and Role of the Prostacyclin (IP) Receptor in Idiopathic Pulmonary Arterial Hypertension

(2010) Emilia Falcetti et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The Extracellular Signal-Regulated Kinase Is Involved in the Effects of Sildenafil on Pulmonary Vascular Remodeling

(2010) Zhen Zeng et al.   Cardiovascular Therapeutics

Smad-Dependent and Smad-Independent Induction of Id1 by Prostacyclin Analogues Inhibits Proliferation of Pulmonary Artery Smooth Muscle Cells In Vitro and In Vivo

(2010) Jun Yang et al.   CIRCULATION RESEARCH

Inhibition of p38 MAPK reverses hypoxia-induced pulmonary artery endothelial dysfunction

(2009) Roshan P. Weerackody et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Hypoxia promotes human pulmonary artery smooth muscle cell proliferation through induction of arginase

(2009) Bernadette Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Altered Bone Morphogenetic Protein and Transforming Growth Factor-β Signaling in Rat Models of Pulmonary Hypertension

(2009) Lu Long et al.   CIRCULATION

Growth factors and interleukin-6 across the lung circulation in pulmonary hypertension

(2009) N. Selimovic et al.   EUROPEAN RESPIRATORY JOURNAL

Bone morphogenetic protein signalling in heritable versus idiopathic pulmonary hypertension

(2009) L. Dewachter et al.   EUROPEAN RESPIRATORY JOURNAL

Activin-Like Kinase 5 (ALK5) Mediates Abnormal Proliferation of Vascular Smooth Muscle Cells from Patients with Familial Pulmonary Arterial Hypertension and Is Involved in the Progression of Experimental Pulmonary Arterial Hypertension Induced by Monocrotaline

(2008) Matthew Thomas et al.   AMERICAN JOURNAL OF PATHOLOGY

Mice expressing BMPR2R899X transgene in smooth muscle develop pulmonary vascular lesions

(2008) James West et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Mutations in Bone Morphogenetic Protein Type II Receptor Cause Dysregulation of Id Gene Expression in Pulmonary Artery Smooth Muscle Cells

(2008) Jun Yang et al.   CIRCULATION RESEARCH

Stoichiometric imbalance in the receptor complex contributes to dysfunctional BMPR-II mediated signalling in pulmonary arterial hypertension

(2008) M. Talat Nasim et al.   HUMAN MOLECULAR GENETICS

Pharmacological PKA Inhibition: All May Not Be What It Seems

(2008) A. J. Murray   Science Signaling