Ca2+-Activated K+Channel–3.1 Blocker TRAM-34 Attenuates Airway Remodeling and Eosinophilia in a Murine Asthma Model

Mast Cells Promote Airway Smooth Muscle Cell Differentiation via Autocrine Up-Regulation of TGF- 1

(2014) L. Woodman et al.   JOURNAL OF IMMUNOLOGY

Blunted IgE-Mediated Activation of Mast Cells in Mice Lacking the Ca2+-Activated K+ Channel KCa3.1

(2014) E. Shumilina et al.   JOURNAL OF IMMUNOLOGY

Improvements in haemolysis and indicators of erythrocyte survival do not correlate with acute vaso-occlusive crises in patients with sickle cell disease: a phase III randomized, placebo-controlled, double-blind study of the gardos channel blocker senicapo

(2011) Kenneth I. Ataga et al.   BRITISH JOURNAL OF HAEMATOLOGY

Functional KCa3.1 K+ channels are required for human fibrocyte migration

(2011) Glenn Cruse et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The KCa3.1 Blocker TRAM-34 Reduces Infarction and Neurological Deficit in a Rat Model of Ischemia/Reperfusion Stroke

(2011) Yi-Je Chen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Airway remodeling in asthma: New mechanisms and potential for pharmacological intervention

(2011) Pierre-Olivier Girodet et al.   PHARMACOLOGY & THERAPEUTICS

Mast cell adhesion to bronchial smooth muscle in asthma specifically depends on CD51 and CD44 variant 6

(2010) P.-O. Girodet et al.   ALLERGY

T Cells Localize with Proliferating Smooth Muscle α-Actin+Cell Compartments in Asthma

(2010) David Ramos-Barbón et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Pathophysiology of bronchial smooth muscle remodelling in asthma

(2010) I. Bara et al.   EUROPEAN RESPIRATORY JOURNAL

CX3CR1 is required for airway inflammation by promoting T helper cell survival and maintenance in inflamed lung

(2010) Cyrille Mionnet et al.   NATURE MEDICINE

The K+channels KCa3.1 and Kv1.3 as novel targets for asthma therapy

(2009) Peter Bradding et al.   BRITISH JOURNAL OF PHARMACOLOGY

Airway remodeling in a mouse asthma model assessed by in-vivo respiratory-gated micro-computed tomography

(2009) Mathieu Lederlin et al.   EUROPEAN RADIOLOGY

Airway remodeling in subjects with severe asthma with or without chronic persistent airflow obstruction

(2009) Marta Kaminska et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mepolizumab and Exacerbations of Refractory Eosinophilic Asthma

(2009) Pranabashis Haldar et al.   NEW ENGLAND JOURNAL OF MEDICINE

Renal fibrosis is attenuated by targeted disruption of KCa3.1 potassium channels

(2009) I. Grgic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diminished sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) expression contributes to airway remodelling in bronchial asthma

(2009) K. Mahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Combined budesonide/formoterol therapy in conjunction with allergen avoidance ameliorates house dust mite-induced airway remodeling and dysfunction

(2008) Jill R. Johnson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Efficacy and safety of the Gardos channel blocker, senicapoc (ICA-17043), in patients with sickle cell anemia

(2008) K. I. Ataga et al.   BLOOD

Airway hyperresponsiveness is dissociated from airway wall structural remodeling

(2008) Salman Siddiqui et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The intermediate-conductance calcium-activated potassium channel KCa3.1 contributes to atherogenesis in mice and humans

(2008) Kazuyoshi Toyama et al.   JOURNAL OF CLINICAL INVESTIGATION