Nebulized Anti–IL-13 Monoclonal Antibody Fab′ Fragment Reduces Allergen-Induced Asthma

Alternatively Activated Macrophages and Airway Disease

(2011) Derek E. Byers et al.   CHEST

Human TH17 cells express a functional IL-13 receptor and IL-13 attenuates IL-17A production

(2011) Dawn C. Newcomb et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Interleukins, from 1 to 37, and interferon-γ: Receptors, functions, and roles in diseases

(2011) Mübeccel Akdis et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IL-13 Antibodies Influence IL-13 Clearance in Humans by Modulating Scavenger Activity of IL-13R 2

(2011) M. T. Kasaian et al.   JOURNAL OF IMMUNOLOGY

Lebrikizumab Treatment in Adults with Asthma

(2011) Jonathan Corren et al.   NEW ENGLAND JOURNAL OF MEDICINE

An open-label, single-dose bioavailability study of the pharmacokinetics of CAT-354 after subcutaneous and intravenous administration in healthy males

(2010) Chad K. Oh et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Asthma and Allergic Inflammation

(2010) Richard M. Locksley   CELL

Cytokine inhibition in severe asthma: current knowledge and future directions

(2010) Jonathan Corren   CURRENT OPINION IN PULMONARY MEDICINE

ADAM-8, a metalloproteinase, drives acute allergen-induced airway inflammation

(2010) Geneviève Paulissen et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

(2010) Daniel R. Neill et al.   NATURE

Neutralisation of Interleukin-13 in Mice Prevents Airway Pathology Caused by Chronic Exposure to House Dust Mite

(2010) Kate L. Tomlinson et al.   PLoS One

A phase 1 study evaluating the pharmacokinetics, safety and tolerability of repeat dosing with a human IL-13 antibody (CAT-354) in subjects with asthma

(2010) Dave Singh et al.   BMC Pulmonary Medicine

Matrix Metalloproteinase-19 Deficiency Promotes Tenascin-C Accumulation and Allergen-Induced Airway Inflammation

(2009) Maud M. Gueders et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Cytokine Antagonists for the Treatment of Asthma

(2009) Sabina Antonela Antoniu   BIODRUGS

Cytokine and anti-cytokine therapy in asthma: ready for the clinic?

(2009) D. Desai et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

IL-13 as a therapeutic target for respiratory disease

(2008) Marion T. Kasaian et al.   BIOCHEMICAL PHARMACOLOGY

In vitro and in vivo characterisation of anti-murine IL-13 antibodies recognising distinct functional epitopes

(2008) L.M. Berry et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Preclinical Safety and Pharmacology of an Anti-Human Interleukin-13 Monoclonal Antibody in Normal Macaques and in Macaques with Allergic Asthma

(2008) Pauline L. Martin et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

The cytokine network in asthma and chronic obstructive pulmonary disease

(2008) Peter J. Barnes   JOURNAL OF CLINICAL INVESTIGATION

A novel formulation of inhaled doxycycline reduces allergen-induced inflammation, hyperresponsiveness and remodeling by matrix metalloproteinases and cytokines modulation in a mouse model of asthma

(2007) Maud M. Gueders et al.   BIOCHEMICAL PHARMACOLOGY