Mitochondrial Dysfunction and Lipid Accumulation in the Human Diaphragm during Mechanical Ventilation

Pulmonary Sarcomatoid Carcinoma Accompanying Duodenal Involvement

(2013) Lae Young Jung et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans

(2011) Silvie Timmers et al.   Cell Metabolism

In Vivo Correction of COX Deficiency by Activation of the AMPK/PGC-1α Axis

(2011) Carlo Viscomi et al.   Cell Metabolism

Mitochondria-targeted antioxidants protect against mechanical ventilation-induced diaphragm weakness*

(2011) Scott K. Powers et al.   CRITICAL CARE MEDICINE

Intrinsic apoptosis in mechanically ventilated human diaphragm: linkage to a novel Fos/FoxO1/Stat3-Bim axis

(2011) Huibin Tang et al.   FASEB JOURNAL

Early versus Late Parenteral Nutrition in Critically Ill Adults

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Chronically elevated glucose compromises myocardial mitochondrial DNA integrity by alteration of mitochondrial topoisomerase function

(2010) S. Medikayala et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Mechanical Ventilation–induced Diaphragm Disuse in Humans Triggers Autophagy

(2010) Sabah N. A. Hussain et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Rapidly Progressive Diaphragmatic Weakness and Injury during Mechanical Ventilation in Humans

(2010) Samir Jaber et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Targeted Expression of Catalase to Mitochondria Prevents Age-Associated Reductions in Mitochondrial Function and Insulin Resistance

(2010) Hui-Young Lee et al.   Cell Metabolism

Interdependence of AMPK and SIRT1 for Metabolic Adaptation to Fasting and Exercise in Skeletal Muscle

(2010) Carles Cantó et al.   Cell Metabolism

Prolonged mechanical ventilation alters diaphragmatic structure and function

(2010) Scott K. Powers et al.   CRITICAL CARE MEDICINE

Metformin selectively attenuates mitochondrial H2O2 emission without affecting respiratory capacity in skeletal muscle of obese rats

(2010) Daniel A. Kane et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidative stress is required for mechanical ventilation-induced protease activation in the diaphragm

(2010) Melissa A. Whidden et al.   JOURNAL OF APPLIED PHYSIOLOGY

Potential Therapeutic Benefits of Strategies Directed to Mitochondria

(2009) Amadou K.S. Camara et al.   ANTIOXIDANTS & REDOX SIGNALING

Ventilator-induced diaphragmatic dysfunction

(2009) Basil J Petrof et al.   Current Opinion in Critical Care

PGC-1α, SIRT1 and AMPK, an energy sensing network that controls energy expenditure

(2009) Carles Cantó et al.   CURRENT OPINION IN LIPIDOLOGY

Mechanical ventilation induces diaphragmatic mitochondrial dysfunction and increased oxidant production

(2009) Andreas N. Kavazis et al.   FREE RADICAL BIOLOGY AND MEDICINE

Role of the respiratory muscles in acute respiratory failure of COPD: lessons from weaning failure

(2009) Martin J. Tobin et al.   JOURNAL OF APPLIED PHYSIOLOGY

Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans

(2009) Ethan J. Anderson et al.   JOURNAL OF CLINICAL INVESTIGATION

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

(2009) Carles Cantó et al.   NATURE

Insulin resistance is a cellular antioxidant defense mechanism

(2009) K. L. Hoehn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lack of CFTR in Skeletal Muscle Predisposes to Muscle Wasting and Diaphragm Muscle Pump Failure in Cystic Fibrosis Mice

(2009) Maziar Divangahi et al.   PLoS Genetics

Resistance training in patients with single, large-scale deletions of mitochondrial DNA

(2008) J. L. Murphy et al.   BRAIN

Mitochondrial fission mediates high glucose-induced cell death through elevated production of reactive oxygen species

(2008) Tianzheng Yu et al.   CARDIOVASCULAR RESEARCH

Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance

(2008) Timothy R. Koves et al.   Cell Metabolism

Molecular mechanisms for myocardial mitochondrial dysfunction in the metabolic syndrome

(2008) Heiko Bugger et al.   CLINICAL SCIENCE

Xanthine oxidase contributes to mechanical ventilation-induced diaphragmatic oxidative stress and contractile dysfunction

(2008) Melissa A. Whidden et al.   JOURNAL OF APPLIED PHYSIOLOGY

The role of exercise and PGC1α in inflammation and chronic disease

(2008) Christoph Handschin et al.   NATURE

What causes mitochondrial DNA deletions in human cells?

(2008) Kim J Krishnan et al.   NATURE GENETICS

Molecular and metabolic mechanisms of insulin resistance and β-cell failure in type 2 diabetes

(2008) Deborah M. Muoio et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Rapid Disuse Atrophy of Diaphragm Fibers in Mechanically Ventilated Humans

(2008) Sanford Levine et al.   NEW ENGLAND JOURNAL OF MEDICINE

Evolution of Mechanical Ventilation in Response to Clinical Research

(2007) Andrés Esteban et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE