Article
Allergy
Felix Forster, Markus Johannes Ege, Jessica Gerlich, Tobias Weinmann, Sylvia Kreissl, Gudrun Weinmayr, Jon Genuneit, Dennis Nowak, Erika von Mutius, Christian Vogelberg, Katja Radon
Summary: Distinct trajectories of asthma and allergy symptoms establish from childhood through adolescence and stabilize during early adulthood. Wheeze-related latent classes showed the strongest positive associations with environmental exposures in adolescence/young adulthood, indicating that not only childhood but also adolescence is relevant for disease development.
Article
Environmental Sciences
Margarete Arrais, Ofelia Lulua, Francisca Quifica, Jose Rosado-Pinto, Jorge M. R. Gama, Philip J. Cooper, Luis Taborda-Barata, Miguel Brito
Summary: This study in Angolan schoolchildren found no consistent associations between intestinal helminth infections and asthma, allergic diseases, or atopy, except for Ascaris lumbricoides, which was inversely associated with rhinoconjunctivitis and directly associated with aeroallergen-specific IgE.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Review
Dermatology
A. M. Andersson, A. S. Halling, N. Loft, L. Skov, A. Koch, E. Guttman-Yassky, J. P. Thyssen
Summary: AD prevalence varies in the Arctic region, with indigenous children having slightly lower risk. The dominant phenotype is mild to moderate flexural dermatitis with facial involvement, and common comorbidities include asthma and allergic rhinitis. Further research is needed to confirm these findings and explore potential behavioral or genetic explanations.
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2021)
Article
Obstetrics & Gynecology
Louise Ekelund, Inga Gloppen, Torbjorn Oien, Melanie Rae Simpson
Summary: The study found that longer breastfeeding reduced the risk of wheeze and showed a protective trend against allergic rhinoconjunctivitis (ARC) in early childhood. However, there were no conclusive associations between the duration of breastfeeding or age at introduction to complementary foods and the prevention of asthma and eczema.
INTERNATIONAL BREASTFEEDING JOURNAL
(2021)
Article
Multidisciplinary Sciences
Francesco De Pretis, Juergen Landes
Summary: Real World Evidence (RWE) and its uses are increasingly important in medical research and inference, with the 21st Century Cures Act in the US allowing the introduction of RWE for risk-benefit assessments of medical interventions. This article introduces an evidence appraisal aggregation algorithm called EA(3) that utilizes the softmax function for evaluating RWE and supporting causal inferences within a Bayesian decision making framework.
Article
Allergy
Sawsan Alnahas, Noura Abouammoh, Wael Althaga, Eman Elsayed Abd-Ellatif
Summary: This study examined the prevalence, severity, and risk factors of allergic rhinitis among schoolchildren in Saudi Arabia. The results showed that the prevalence of rhinoconjunctivitis is lower in children compared to the global average, but within the global average range for adolescents. Further research is needed to explore regional differences and track trends over time.
WORLD ALLERGY ORGANIZATION JOURNAL
(2023)
Article
Allergy
Iva Mrkic Kobal, Helena Munivrana Skvorc, Marko Skvorc, Stefanija Munivrana
Summary: The study conducted in Medimurje County, Northwestern Croatia, showed a significant increase in the prevalence of asthma, allergic rhinitis, allergic rhinoconjunctivitis, and atopic dermatitis among children aged 12-14 years over 8 years. When comparing the age group 12-14 years in 2005 with the age group 18 years in 2013, there was also a significant increase in symptoms of these atopic diseases.
ALLERGOLOGIA ET IMMUNOPATHOLOGIA
(2021)
Article
Allergy
Brian Stone, Karen Rance, Douglas Waddell, Mark Aagren, Eva Hammerby, Joseph P. Tkacz
Summary: This study utilized claims data from AR patients in the United States to assess AIT use and outcomes. Patients who reached AIT maintenance had better outcomes and higher baseline comorbidity rates compared to the full AIT cohort and patients without AIT claims.
ALLERGY AND ASTHMA PROCEEDINGS
(2021)
Article
Clinical Neurology
Hee-Kyung Joh, Hyuktae Kwon, Ki Young Son, Jae Moon Yun, Su Hwan Cho, Kyungdo Han, Jin-Ho Park, Belong Cho
Summary: This study examines the association between the allergic triad (asthma, allergic rhinitis, atopic dermatitis) and the risk of dementia. The results indicate that allergic diseases are positively associated with dementia risk, and the severity of allergic diseases has a dose-effect relationship with dementia risk.
ANNALS OF NEUROLOGY
(2023)
Article
Public, Environmental & Occupational Health
Weiliang Kong, Yilian Xie, Jingjing Zhong, Chao Cao
Summary: This study further supports the association between ultra-processed foods (UPFs) and IgE levels, current asthma in children, and eczema in girls. No association between UPFs and allergic symptoms was observed in adults.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Allergy
Rachel L. Peters, Tegan Kay, Vicki L. McWilliam, Caroline J. Lodge, Anne-Louise Ponsonby, Shyamali C. Dharmage, Adrian J. Lowe, Jennifer J. Koplin
Summary: The study found that longer duration of breastfeeding was associated with a reduced odds of asthma among children without eczema in the first year of life, but not in children with eczema. Early manifestations of allergic disease may impact breastfeeding behavior.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
(2021)
Article
Multidisciplinary Sciences
Seung Won Lee, Jiwon Park, Hayeon Kim, Yong Woo Jung, Yoo Sang Baek, Yejee Lim, Kyungim Kim
Summary: This nationwide matched cohort study found that atopic dermatitis (AD) is associated with an increased risk of gastroesophageal reflux disease (GERD). Appropriate management should be considered in adults with AD to prevent GERD.
Article
Allergy
Jessica Atwell, Martha Chico, Maritza Vaca, Andrea Arevalo-Cortes, Ruth Karron, Philip J. J. Cooper
Summary: This study in Ecuador found that early viral respiratory diseases contribute to childhood respiratory illnesses, especially in the presence of airway inflammation-related infections. The associations between wheezing illness, asthma, and rhinoconjunctivitis were examined in relation to early viral respiratory diseases and other factors.
CLINICAL AND TRANSLATIONAL ALLERGY
(2023)
Article
Allergy
Zarqa Ali, Charlotte Suppli Ulrik, Alexander Egeberg, Jacob Pontoppidan Thyssen, Simon Francis Thomsen
Summary: Excess mortality has been reported for adults with atopic dermatitis (AD) and asthma. This study found that adults with both AD and asthma have an increased risk of death compared to those with asthma alone, but not compared to those with AD only. Adults with AD, asthma, or both conditions have an increased risk of death.
CLINICAL AND EXPERIMENTAL ALLERGY
(2021)
Article
Allergy
Nicklas Brustad, Alessandra Olarini, Min Kim, Liang Chen, Mina Ali, Tingting Wang, Arieh S. Cohen, Madeleine Ernst, David Hougaard, Ann-Marie Schoos, Jakob Stokholm, Klaus Bonnelykke, Jessica Lasky-Su, Morten A. Rasmussen, Bo Chawes
Summary: This study aimed to investigate the influence of vertically transferred metabolites on the risk of atopic diseases and infections in preschool-age children.
PEDIATRIC ALLERGY AND IMMUNOLOGY
(2023)
Article
Public, Environmental & Occupational Health
William Mueller, Miranda Loh, Tony Fletcher, Sarah Rhodes, Lucy Pembrey, Neil Pearce, Martie van Tongeren
Summary: This study investigated the burden of COVID-19 in the UK food and drink processing industry. The results showed that infection rates were associated with deprivation, proportions of remote workers and workers in close proximity, and the number of workers.
ANNALS OF WORK EXPOSURES AND HEALTH
(2023)
Article
Dermatology
Stephanie J. Lax, Amanda Roberts, Eleanor Cliffe, Grishma Ramesh, Dija Ayodele, Hywel C. Williams, Sharon Belmo, Paul Leighton
Summary: Our study found that the Fitzpatrick Scale fails to accurately reflect how individuals perceive their own skin tone. Respondents provided diverse descriptions of their skin tone, with some acknowledging the impact of social inequalities on their language choices. In order to create comprehensive and inclusive tools, it is crucial to incorporate the perspectives of patients.
BRITISH JOURNAL OF DERMATOLOGY
(2023)
Review
Dermatology
Carolyn Charman, Hannah Wainman, Aswatha Rabindranathnambi, Chin Whybrew, Hywel C. Williams
Summary: The COVID-19 pandemic has accelerated the rapid expansion of digital Advice and Guidance (A&G) in medical and surgical specialties in the UK, particularly in dermatology. Limited guidance exists on what constitutes a high-quality A&G request and response. This educational article discusses good clinical practice based on extensive experience from primary and secondary care doctors.
CLINICAL AND EXPERIMENTAL DERMATOLOGY
(2023)
Review
Dermatology
Sophie Leducq, Natalie Bonsu, Kate Clement, Richard Barlow, Hywel C. Williams
Summary: This educational review defines predatory journals and conferences, highlights their distinguishing features, and summarizes the consequences of publishing in or attending them. It also outlines tools available to recognize and avoid predation.
CLINICAL AND EXPERIMENTAL DERMATOLOGY
(2023)
Editorial Material
Public, Environmental & Occupational Health
Neil Pearce, Jan P. Vandenbroucke
Article
Public, Environmental & Occupational Health
Angela Pinot De Moira, Neil Pearce, Marie Pedersen, Anne-Marie Nybo Andersen
Summary: This study explored factors that may modify associations of early-life animal exposure with asthma and allergic disease, and found that type of animal, source of exposure, parental history of asthma or allergy, and timing of exposure can modify these associations. It is important to consider these factors when assessing the risks associated with early-life animal exposure.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2023)
Editorial Material
Respiratory System
Richard Beasley, Pepa Bruce, Lee Hatter
Article
Immunology
Marjan Doppen, Cilein Kearns, Mark Weatherall, Nethmi Kearns, Peter McIntyre, Thomas Hills, Richard Beasley
Summary: This study aimed to determine the thresholds for Body Mass Index (BMI) and arm circumference above which a longer needle is needed for intramuscular (IM) delivery of a vaccine in the deltoid muscle at the recommended site in New Zealand. The analysis of two studies involving 442 adults showed that higher arm circumference and BMI values were associated with the need for a longer needle. Based on the findings, men with an arm circumference of 35 cm and women with an arm circumference of 30 cm should use a longer needle to ensure successful intramuscular injection.
Article
Medicine, General & Internal
Tae Yoon Lee, Mohsen Sadatsafavi, Chandra Prakash Yadav, David B. Price, Richard Beasley, Christer Janson, Mariko Siyue Koh, Rupsa Roy, Wenjia Chen
Summary: This study aims to develop and validate a novel risk prediction model for severe exacerbations in patients with severe asthma, and to examine the potential clinical utility of this tool.
Article
Infectious Diseases
Nicole Maison, Jimmy Omony, Sophia Rinderknecht, Laura Kolberg, Melanie Meyer-Buehn, Erika von Mutius, Johannes Huebner, Ulrich von Both
Summary: Following COVID-19 lockdown measures, respiratory tract infections increased worldwide, specifically affecting children's hospitals. Changes in the epidemiological pattern of respiratory viral infections were observed, with a higher number of virus detections and a shift in the pattern of infections.
Article
Public, Environmental & Occupational Health
Pilar Tavares Veras Florentino, Thiago Cerqueira-Silva, Luciana Freire De Carvalho, Flavia Jose Oliveira Alves, Vinicius De Araujo Oliveira, Gislani Mateus Oliveira Aguilar, Rodrigo De Sousa Prado, Daniel Soranz, Neil Pearce, Viviane Boaventura, Guilherme Loreiro Werneck, Gerson Oliveira Penna, Mauricio Lima Barreto, Marcio Henrique De Oliveira Garcia, Manoel Barral-Netto, Enny Santos da Paixao
Summary: This study provides evidence that COVID-19 vaccination during pregnancy, regardless of the vaccine type (CoronaVac or BNT162b2), is safe and does not increase the risk of adverse birth outcomes or neonatal deaths.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2023)
Letter
Allergy
Jasmijn A. Schrumpf, Dennis K. Ninaber, Christoph Mueller, Bettina Rankl, Erika von Mutius, Hermelijn H. Smits, Pieter S. Hiemstra
PEDIATRIC ALLERGY AND IMMUNOLOGY
(2023)
Review
Respiratory System
Mike Thomas, Richard Beasley
Summary: The treatable traits approach is a personalized management method for asthma and chronic obstructive airways disease (COPD), based on recognizing the heterogeneous nature of these conditions and the importance of treating specific clinical features. The implementation of this approach within resource constraints is still uncertain.
Article
Medicine, General & Internal
Nethmi Kearns, Neakiry Kivi, Emily Dickinson, Emma Mayo, Allie Eathorne, Augustus Anderson, Richard Beasley, Craig Thornley, Annette Nesdale
Summary: This study investigated the prevalence of ongoing symptoms and laboratory abnormalities in confirmed COVID-19 cases from the first wave in the Greater Wellington Region, New Zealand, at least 12 months post infection. The results showed a high prevalence of ongoing symptoms, with many participants reporting worse overall health compared to before contracting COVID-19. Additionally, 90% of participants reported having at least two ongoing symptoms. However, there were minimal laboratory abnormalities detected. It should be noted that this was an observational, cross-sectional study, so a causal relationship between symptoms and COVID-19 infection could not be firmly established.
NEW ZEALAND MEDICAL JOURNAL
(2023)
Correction
Respiratory System
Paola Rogliani, Rossella Laitano, Josuel Ora, Richard Beasley, Luigino Calzetta
EUROPEAN RESPIRATORY REVIEW
(2023)