Pulmonary Arterial Hypertension in Rats Due to Age-Related Arginase Activation in Intermittent Hypoxia

Hypobaric hypoxia induced arginase expression limits nitric oxide availability and signaling in rodent heart

(2014) Manjulata Singh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Arginase as a potential target in the treatment of cardiovascular disease: reversal of arginine steal?

(2013) John Pernow et al.   CARDIOVASCULAR RESEARCH

Arginase: The Emerging Therapeutic Target for Vascular Oxidative Stress and Inflammation

(2013) Zhihong Yang et al.   Frontiers in Immunology

Role of Arginase in Vessel Wall Remodeling

(2013) William Durante   Frontiers in Immunology

Altered Neuronal Nitric Oxide Synthase in the Aging Vascular System: Implications for Estrogens Therapy

(2012) Olga Lekontseva et al.   ENDOCRINOLOGY

Reactive oxygen and nitrogen species in pulmonary hypertension

(2012) Diana M. Tabima et al.   FREE RADICAL BIOLOGY AND MEDICINE

Tackling endothelial dysfunction by modulating NOS uncoupling: new insights into its pathogenesis and therapeutic possibilities

(2011) Rinrada Kietadisorn et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Early Macrophage Recruitment and Alternative Activation Are Critical for the Later Development of Hypoxia-Induced Pulmonary Hypertension

(2011) Eleni Vergadi et al.   CIRCULATION

Relationship of electrophilic stress to aging

(2011) Piotr Zimniak   FREE RADICAL BIOLOGY AND MEDICINE

Intermittent hypoxia augments pulmonary vascular smooth muscle reactivity to NO: regulation by reactive oxygen species

(2011) Charles E. Norton et al.   JOURNAL OF APPLIED PHYSIOLOGY

Hypoxic upregulation of arginase II in human lung endothelial cells

(2010) Karina Krotova et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Aldehyde dehydrogenase 2 (ALDH2) rescues myocardial ischaemia/reperfusion injury: role of autophagy paradox and toxic aldehyde

(2010) Heng Ma et al.   EUROPEAN HEART JOURNAL

Correlation of pulmonary hypertension severity with metrics of comorbid sleep-disordered breathing

(2010) Douglas L. Prisco et al.   Sleep and Breathing

Chronic intermittent hypobaric hypoxia protects the heart against ischemia/reperfusion injury through upregulation of antioxidant enzymes in adult guinea pigs

(2009) Hui-cai Guo et al.   ACTA PHARMACOLOGICA SINICA

eNOS uncoupling and endothelial dysfunction in aged vessels

(2009) Yang-Ming Yang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Oxidative stress and endothelial dysfunction in pulmonary arteries of aged rats

(2009) Andrej Podlutsky et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Hypoxia promotes human pulmonary artery smooth muscle cell proliferation through induction of arginase

(2009) Bernadette Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats

(2009) Jae Hyung Kim et al.   JOURNAL OF APPLIED PHYSIOLOGY

Persistent eNOS activation secondary to caveolin-1 deficiency induces pulmonary hypertension in mice and humans through PKG nitration

(2009) You-Yang Zhao et al.   JOURNAL OF CLINICAL INVESTIGATION

Obstructive Sleep Apnea and Pulmonary Hypertension

(2009) Dimitar Sajkov et al.   PROGRESS IN CARDIOVASCULAR DISEASES

The Role of NADPH Oxidase in Chronic Intermittent Hypoxia-Induced Pulmonary Hypertension in Mice

(2008) Rachel E. Nisbet et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Arginase and vascular aging

(2008) Lakshmi Santhanam et al.   JOURNAL OF APPLIED PHYSIOLOGY

Arginase and pulmonary diseases

(2008) Harm Maarsingh et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY