Article
Medicine, General & Internal
Jingjing Luo, Xinan Wu, Xue Gang, Nana Zhang, Feifei Wang, Chengting Rong
Summary: This article reports a rare case of artificial joint infection caused by Mycoplasma hominis and Ureaplasma urealyticum. The patient recovered well after appropriate treatment, with no evidence of infection recurrence during the follow-up period.
Article
Infectious Diseases
Ian Boostrom, Yohan Bala, Jelena Minic Vasic, Jelena Gluvakov, Emmanuel Chanard, Andrew H. Barratt, Kirsty Sands, Edward Portal, Laurence Devigne, Lucy C. Jones, Owen B. Spiller
Summary: The study evaluated the accuracy, sensitivity and specificity of MYCOPLASMA IST3, showing promising results in detecting urogenital mycoplasma infections.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2021)
Article
Immunology
Erica L. Plummer, Lenka A. Vodstrcil, Kaveesha Bodiyabadu, Gerald L. Murray, Michelle Doyle, Rosie L. Latimer, Christopher K. Fairley, Matthew Payne, Eric P. F. Chow, Suzanne M. Garland, Catriona S. Bradshaw
Summary: The study found that only Mycoplasma hominis was associated with symptoms/signs in nonpregnant women, specifically related to bacterial vaginosis. Ureaplasma species were not associated with symptoms/signs. Therefore, routine testing for Mycoplasma hominis, Ureaplasma urealyticum, and Ureaplasma parvum in nonpregnant women is not supported.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Infectious Diseases
Can Wang, Jingshuang Wang, Juan Yan, Feng Chen, Ying Zhang, Xuelian Hu
Summary: This article reports four cases of peritoneal dialysis (PD)-associated peritonitis caused by Mycoplasma hominis, Ureaplasma parvum, and Ureaplasma urealyticum, along with a literature review. The four cases were female patients with recurrent culture-negative PD-associated peritonitis, which was related to menstruation. These pathogens were detected in the PD fluid of the patients using metagenomic next-generation sequencing. All four patients were cured by intraperitoneal tigecycline combined with oral azithromycin or minocycline. Mycoplasma hominis, Ureaplasma parvum, and Ureaplasma urealyticum should be given more attention in female patients with recurrent culture-negative PD-associated peritonitis, especially when it is related to menstruation, sexual intercourse, or urogenital tract operation. Moreover, metagenomic next-generation sequencing can provide a reasonable method to identify the pathogen for culture-negative PD-associated peritonitis.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2023)
Article
Infectious Diseases
Su Zhang, Ke Xu, Su-Xiao Liu, Xiao-Lan Ye, Ping Huang, Hong-Juan Jiang
Summary: This study investigated the prevalence of azithromycin-resistant U. urealyticum and M. hominis infections in pregnant women and explored the possible influencing factors and consequences of insensitive Mycoplasma infection. It was found that azithromycin-resistant cervical Mycoplasma infection in pregnant women was associated with a significantly increased incidence of adverse pregnancy outcomes.
INFECTION AND DRUG RESISTANCE
(2023)
Article
Biology
Wei-wei Zheng, Wen-jing Zhang, Di Cui, Zheng-chao Nie, Bang-sheng Ding, Jiang-hua Cheng, Chuan-zhong Mei
Summary: The study revealed a high infection rate of Ureaplasma urealyticum and Mycoplasma hominis in the genitourinary tract of Chinese patients, primarily affecting individuals aged 21-40 years, with variations in antibiotic sensitivity.
BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH
(2021)
Article
Immunology
Amin Dehghan, Mohammad Reza Pourmand, Vahid Salimi, Firouzeh Akbari Asbagh, Abbas Rahimi Foroushani, Kaveh Sadeghi, Samaneh Hosseini Quchani
Summary: This study investigated the impact of CT, MH, and UU infections on semen quality and found that these infections significantly affect the quality and properties of male reproductive health.
MICROBIAL PATHOGENESIS
(2022)
Article
Medical Laboratory Technology
Ruixiang Luo, Kang Xun, Lingli Zuo, Feifei Sha, Yun Chen, Nong Yu, Donghua Jin, Yuxian Xie, Meiling He, Fang Liu
Summary: This study investigated the infection and antimicrobial resistance of Ureaplasma urealyticum and Mycoplasma hominis in patients with genital tract diseases in Jiangsu, China. The results showed a high prevalence of U. urealyticum mono-infections and an increasing overall infection rate in the past 3 years. Females had a higher infection rate than males, and the main age group affected was 20-39. The antimicrobial resistance rates varied for different drugs, with lower resistance observed for gatifloxacin, josamycin, minocycline, and doxycycline, and higher resistance observed for azithromycin, clindamycin, roxithromycin, sparfloxacin, and ofloxacin. The antimicrobial resistance of U. urealyticum and M. hominis to these drugs has been changing in the past 3 years.
CLINICAL LABORATORY
(2022)
Article
Medical Laboratory Technology
Ruixiang Luo, Kang Xun, Lingli Zuo, Feifei Sha, Yun Chen, Nong Yu, Donghua Jin, Yuxian Xie, Meiling He, Fang Liu
Summary: This study aimed to investigate the infection and antimicrobial resistance of Ureaplasma urealyticum and Mycoplasma hominis in patients with genital tract diseases in Jiangsu, China. The results showed an increasing infection rate over the past 3 years, with higher rates in females and the 20-39 age group. U. urealyticum and M. hominis displayed relatively lower resistance rates to certain antibiotics, but higher resistance rates to others.
CLINICAL LABORATORY
(2021)
Review
Infectious Diseases
Mohammad H. Ahmadi
Summary: The global status of resistance to tetracyclines in Mycoplasma hominis and Ureaplasma species is relatively high and prevalent, with high levels of heterogeneity observed in all studies except for doxycycline resistance in M. hominis isolates. This highlights the importance of regional and local antibiotic susceptibility testing before treatment choice, as well as the development of newer generations of tetracyclines to prevent antibiotic misuse, emergence and spread of resistant strains, and treatment failure.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2021)
Article
Medical Laboratory Technology
Lu-Qing Zheng, Qing-Yong Wang
Summary: We retrospectively reviewed reports of 4,166 female outpatients detected by the mycoplasma identification verification and antibiotic susceptibility kit from the last five years. Among them, more than 73.3% of cases with Ureaplasma urealyticum or Mycoplasma hominis single infection or co-infection with both species were susceptible to three tetracyclines and one macrolide (josamycin). Additionally, more than 84.8%, less than 4.4%, and less than 39.6% of the U. urealyticum, M. hominis, and co-infection cases, respectively, were susceptible to clarithromycin and roxithromycin. Four quinolones (ciprofloxacin, ofloxacin, sparfloxacin, and levofloxacin) and three macrolides (azithromycin, erythromycin, and acetylspiramycin) were active against less than 48.9% of the isolates. Furthermore, 77.8%, 18.4%, and 7.5% of the M. hominis, U. urealyticum, and co-infection cases, respectively, were susceptible to spectinomycin.
CLINICAL LABORATORY
(2023)
Article
Medicine, General & Internal
Bogdan Doroftei, Ovidiu-Dumitru Ilie, Theodora Armeanu, Emil Anton, Ioana Scripcariu, Radu Maftei
Summary: The prevalence of Ureaplasma urealyticum (UU) and Mycoplasma hominis (MH) among infertile women was 31.87%, with the most affected age group being women between thirty and thirty-five years old. The most efficient antibiotics in eradicating UU and MH were Pristinamycin and Josamycin, with other effective options including Doxycycline, Minocycline, Tetracycline, and Erythromycin.
MEDICINA-LITHUANIA
(2021)
Article
Infectious Diseases
Oliver Spiller-Boulter, Susanne Paukner, Ian Boostrom, Kirsty Sands, Edward A. R. Portal, Owen B. Spiller
Summary: Lefamulin, the first pleuromutilin antimicrobial available for human use, shows promising in vitro activity against Ureaplasma spp. and Mycoplasma hominis infections, regardless of intrinsic or acquired resistance to macrolides, lincosamides, and ketolides. Further exploration of its clinical efficacy in treating urogenital infections caused by these pathogens is warranted.
Article
Infectious Diseases
Ling Shao, Xiaoli Wu, Shiwei Gao, Liwen Liu, Yunli Zhang, Hongmei Zhao
Summary: A study conducted in a comprehensive teaching hospital in Shenyang, China found increasing rates of Ureaplasma urealyticum and Mycoplasma hominis infection over the past 4 years, particularly among younger age groups. The infection rates were significantly higher in females than in males, especially in females aged 25-29 and 15-19.
JOURNAL OF INFECTION AND CHEMOTHERAPY
(2021)
Article
Microbiology
Yingying Kong, Chao Li, Gangfeng Li, Ting Yang, Mohamed S. Draz, Xinyou Xie, Jun Zhang, Zhi Ruan
Summary: Fluoroquinolone resistance in Mycoplasma hominis and Ureaplasma spp. is increasing globally. This study evaluated the antimicrobial activity of two new fluoroquinolones, delafloxacin and finafloxacin, for the first time, against clinical isolates of M. hominis and Ureaplasma spp. The results showed that delafloxacin had lower minimum inhibitory concentrations against fluoroquinolone-resistant isolates of both M. hominis and Ureaplasma spp.
MICROBIOLOGY SPECTRUM
(2022)
Article
Engineering, Aerospace
Bernardo Luiz R. Ribeiro, Jennifer A. Franck
Summary: A machine learning model is developed to establish wake patterns behind oscillating foils for energy harvesting. The wake is parameterized based on input kinematic variables and classified using image analysis. The results can be used to predict the performance of foils in the wake and determine optimal foil arrangements.
Review
Oncology
David Hui, Bianca Sakamoto Ribeiro Paiva, Carlos Eduardo Paiva
Summary: The specialty of palliative care has evolved to provide symptom management, psychosocial support, and care planning for cancer patients. This review examines the delivery and impact of palliative care in outpatient, inpatient, and community-based settings. It discusses how these three branches of palliative care can work together to optimize patient outcomes under a unified model.
CURRENT TREATMENT OPTIONS IN ONCOLOGY
(2023)
Article
Medicine, General & Internal
Bianca Sakamoto Ribeiro Paiva, Talita Caroline de Oliveira Valentino, Mirella Mingardi, Marco Antonio de Oliveira, Julia Onishi Franco, Michelle Couto Salerno, Helena Palocci, Tais Cruz de Melo, Carlos Eduardo Paiva
Summary: This study translates and cross-culturally adapts the Quality of Dying and Death Questionnaire (QoDD) into Brazilian Portuguese and measures its validity and internal consistency. The results show that the QoDD-Br is a culturally adapted valid instrument that can be used to assess the quality of death in cancer patients.
SAO PAULO MEDICAL JOURNAL
(2023)
Article
Anatomy & Morphology
W. J. Favaro, J. C. C. Alonso, B. R. de Souza, I. B. Reis, J. M. Goncalves, A. C. Deckmann, G. Oliveira, Q. C. Dias, N. Duran
Summary: BCG-based intravesical immunotherapy is the gold standard treatment for high-risk non-muscle invasive bladder cancer. However, some high-risk patients experience relapse and do not respond to BCG. Our research group developed OncoTherad (R) nano-immunotherapy, which showed positive outcomes and mechanisms of action in an animal model with NMIBC. OncoTherad (R) nano-immunotherapy was more effective than BCG treatment, reducing the malignancy rate by 70% through modulation of TLR4-mediated interferon and RANK/RANKL signaling pathways.
Review
Pharmacology & Pharmacy
Gilbert G. G. Donders, Francesca H. W. V. Donders
Summary: Proper recognition and personalized therapy are crucial for vulvovaginal atrophy (VVA). The assessment of VVA should include questionnaires, wet mount microscopy, and the determination of Vaginal Cell Maturation Index (VCMI) and infections. Low dose vaginal estriol is safe and efficient, making it the first choice hormonal treatment for women with contraindications for steroid hormones. New estrogens, androgens, and SERMs are being developed and tested, and alternative therapies such as intravaginal Hyaluronic Acid (HA) or Vit D may be suitable for women who cannot or do not want to use hormones. Proper diagnosis, including microscopy of vaginal fluid, is essential for effective treatment. Low dose vaginal estrogen treatment, especially with estriol, is preferred for most women. Oral ospemifene and vaginal dihydroepiandrosterone (DHEA) are considered safe and efficient alternative therapies. More safety data are awaited for several SERMs and a newly introduced estrogen: estetrol (E4). The indications for laser treatments are questionable.
EXPERT OPINION ON PHARMACOTHERAPY
(2023)
Review
Health Care Sciences & Services
Bruna dos Santos Carmo, Mayara Goulart de Camargos, Martins Fidelis dos Santos Neto, Bianca Sakamoto Ribeiro Paiva, Giancarlo Lucchetti, Carlos Eduardo Paiva
Summary: This review examines the relationship between religiosity/spirituality/religious-spiritual coping and end-of-life (EOL) care preferences and receipt in cancer patients. The results show that religiosity/spirituality is associated with more aggressive EOL care and lower rates of advance care planning. Spiritual care from the medical team is associated with more referrals to hospice and less aggressive care, while high spiritual support from religious communities is associated with less hospice and more aggressive care.
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
(2023)
Article
Computer Science, Artificial Intelligence
Luis Torres, Joel P. Arrais, Bernardete Ribeiro
Summary: Graph neural networks and convolutional architectures have played a key role in improving molecular property prediction in drug discovery. However, this is a low data problem, which is incompatible with regular deep learning approaches. In this paper, the authors address this challenge by defining deep learning architectures that accept compound chemical structures as molecular graphs, creating a few-shot learning strategy across graph neural networks and convolutional neural networks, and proposing a two-module meta-learning framework to predict molecular properties on few-shot data.
NEURAL COMPUTING & APPLICATIONS
(2023)
Editorial Material
Pediatrics
Bruna Ribeiro de Andrade Ramos, Jossimara Polettini, Marcia Guimaraes da Silva
FRONTIERS IN PEDIATRICS
(2023)
Article
Microbiology
Jefferson Luiz da Silva, Lia Vezenfard Barbosa, Camila Figueiredo Pinzan, Viviani Nardini, Irislene Simoes Brigo, Cassia Aparecida Sebastiao, Jefferson Elias-Oliveira, Vania Brazao, Jose Clovis do Prado Junior, Daniela Carlos, Cristina Ribeiro de Barros Cardoso
Summary: Dysbiosis and disturbances in gut homeostasis can lead to dysregulated responses in inflammatory bowel diseases. Melatonin has shown potential as a therapeutic option due to its interactions with immune responses and gut microbiota. In this study, MLT treatment increased inflammation in acute colitis and delayed recovery during remission.
Article
Infectious Diseases
Gabriel Vitor da Silva Pinto, Aline do Nascimento Bolpet, Laura Fernandes Martin, Natalia Prearo Moco, Bruna Ribeiro de Andrade Ramos, Mariana de Castro Silva, Marli Teresinha Casamassimo Duarte, Andrea da Rocha Tristao, Marcia Guimaraes da Silva, Camila Marconi
Summary: This study aimed to determine the prevalence and factors associated with Trichomonas vaginalis infection among women of reproductive age. The results showed an overall prevalence of T. vaginalis infection of 1.3%, and it was found to be associated with factors such as ethnicity, smoking, and bacterial vaginosis. These data suggest that screening programs can be helpful in guiding prevention strategies in the community.
BRAZILIAN JOURNAL OF INFECTIOUS DISEASES
(2023)
Article
Nutrition & Dietetics
Livia Costa de Oliveira, Karla Santos da Costa Rosa, Thamiris Gaspar, Bianca Sakamoto Ribeiro Paiva, Carlos Eduardo Paiva, Wilza Arantes Ferreira Peres
Summary: This study aimed to evaluate the clinical usefulness of assessing nutritional status in palliative care patients with incurable cancer. The results showed that cancer cachexia was the only nutritional status parameter associated with function. Additionally, factors such as white skin color, higher educational level, and inadequate calorie intake were also found to be associated with the outcome.
Article
Multidisciplinary Sciences
James B. Dorey, Erica E. Fischer, Paige R. Chesshire, Angela Nava-Bolanos, Robert L. O'Reilly, Silas Bossert, Shannon M. Collins, Elinor M. Lichtenberg, Erika M. Tucker, Allan Smith-Pardo, Armando Falcon-Brindis, Diego A. Guevara, Bruno Ribeiro, Diego de Pedro, John Pickering, Keng-Lou James Hung, Katherine A. Parys, Lindsie M. McCabe, Matthew S. Rogan, Robert L. Minckley, Santiago J. E. Velazco, Terry Griswold, Tracy A. Zarrillo, Walter Jetz, Yanina V. Sica, Michael C. Orr, Laura Melissa Guzman, John S. Ascher, Alice C. Hughes, Neil S. Cobb
Summary: This study presents the BeeBDC package and a global bee occurrence dataset, which address the limited availability and reliability of bee species data. By combining and cleaning millions of records, the authors provide users with clean and flagged bee occurrence data, along with the ability to modify filtering parameters.
Article
Energy & Fuels
Luis Fernando Marin Sepulveda, Marcelo Gattass, Aristofanes Correa Silva, Roberto Quevedo, Diogo Michelon, Carlos Siedschlag, Roberto Ribeiro
Summary: This article introduces a domain adaptation method based on comparing seismic features, which is used to detect natural gas in 2D seismic data. The proposed method does not require modifying the training data or DL model architecture, but focuses on analyzing the training data to recognize patterns for comparing and clustering similar seismic data. Compared to the DL model trained with all available seismic data, the proposed method achieves significant improvements in precision, recall, F1 score, and IoU.
GEOENERGY SCIENCE AND ENGINEERING
(2023)
Article
Medicine, General & Internal
Bianca Sakamoto Ribeiro Paiva, Bruna Minto Lourenco, Henrique Moraes Prata, Talita Caroline de Oliveira Valentino, Marco Antonio de Oliveira, Martins Fideles dos Santos Neto, Eduardo Bruera, Carlos Eduardo Paiva
Summary: This study aimed to evaluate the percentage of cancer patients who prefer cremation and identify the factors associated with this preference. The results showed that the majority of cancer patients in Brazil prefer burial. However, discussions about death, religious beliefs, and educational level seem to influence the preference for cremation.
SAO PAULO MEDICAL JOURNAL
(2023)
Article
Computer Science, Artificial Intelligence
Mario Alberto da Silveira Dib, Pedro Prates, Bernardete Ribeiro
Summary: With the ongoing digitization of the manufacturing industry, machine learning techniques have great potential in predicting defects and improving production process reliability. However, small and medium-sized companies lack sufficient data for applying machine learning models. This paper proposes a framework based on Federated Learning and Digital Envelopes to address data privacy concerns and effectively handle data poisoning attacks.
EXPERT SYSTEMS WITH APPLICATIONS
(2024)
