Article
Forestry
Caleb M. McKinney, Ronald E. Masters, Arjun Adhikari, Bijesh Mishra, Omkar Joshi, Chris B. Zou, Rodney E. Will
Summary: White-tailed deer hunting in the USA is a significant economic activity, with annual expenditures of over $12.9 billion. Thinning and prescribed fire can enhance deer forage quantity and quality. The study evaluated the long-term effects of different combinations of fire return intervals and tree harvest on forage productivity and protein content. The results showed that frequent fire maintenance in savanna systems resulted in significantly greater aboveground net primary production (ANPP) and increased protein concentrations of understory species in forests can provide higher quality forage in summer when deer have higher nutritional demands. Balancing a mix of savanna and woodland may be ideal for optimizing forage quantity and protein content.
FOREST ECOLOGY AND MANAGEMENT
(2023)
Review
Cell Biology
Gunter Emons, Carsten Gruendker
Summary: Endometrial cancer expresses GnRH and its receptor, which can regulate proliferation, the cell cycle, and apoptosis. GnRH agonists are used in fertility preserving therapy for early EC, but show limited activity in advanced or recurrent EC. Further clinical trials exploring the GnRH-system in EC may be beneficial.
Article
Biology
Chirine Toufaily, Jerome Fortin, Carlos A. Alonso, Evelyne Lapointe, Xiang Zhou, Yorgui Santiago-Andres, Yeu-Farn Lin, Yiming Cui, Ying Wang, Dominic Devost, Ferdinand Roelfsema, Frederik Steyn, Aylin C. Hanyaloglu, Terence E. Hebert, Tatiana Fiordelisio, Derek Boerboom, Daniel J. Bernard
Summary: Gonadotropin-releasing hormone (GnRH) controls reproduction by stimulating FSH and LH synthesis via its receptor GnRHR, but the lack of Ctail in mammalian GnRHR may not provide an advantage for LH surge generation. In transgenic mice, addition of Ctail resulted in reduced FSH production and fertility, suggesting a potential role of Ctail in normal reproductive function.
Review
Cell Biology
Carsten Gruendker, Guenter Emons
Summary: The HPG axis regulates the female menstrual cycle through GnRH, which can impact ovarian cancer either indirectly through the HPG axis or directly through receptors on the surface of tumor cells.
Article
Plant Sciences
Letian Han, Shan Xiang, Baohai Rong, Yanchen Liang, Shengtian Zhao
Summary: Verbascoside (VB) has protective effects on reproductive organs and may be therapeutically useful in the treatment of varicocele through up-regulation of the HPG axis.
PHARMACEUTICAL BIOLOGY
(2021)
Article
Immunology
Ai-Mei Chang, Chen-Chih Chen, Ding-Liang Hou, Guan-Ming Ke, Jai-Wei Lee
Summary: The study revealed that GnRH vaccine can reduce hormone concentrations, lead to testicular atrophy and decreased sperm quality, and have an impact on animal mating and reproductive abilities.
Review
Chemistry, Medicinal
Yi-Fu Liu, Sheng-Qiang Fu, Yu-Chang Yan, Bin-Bin Gong, Wen-Jie Xie, Xiao-Rong Yang, Ting Sun, Ming Ma
Summary: This review discusses the usage, administration, and impact on serum testosterone levels of GnRH receptor agonists and antagonists, focusing on the mechanism of action of the antagonists and their development in clinical studies.
DRUG DESIGN DEVELOPMENT AND THERAPY
(2021)
Article
Agriculture, Dairy & Animal Science
Tracy A. Burnett, Augusto M. L. Madureira, Janet W. Bauer, Ronaldo L. A. Cerri
Summary: This study found that administration of GnRH at the time of artificial insemination can improve fertility in cows with reduced estrous expression, but increased ovulation rate does not seem to be the direct mechanism behind this relationship.
JOURNAL OF DAIRY SCIENCE
(2022)
Article
Multidisciplinary Sciences
Lisa-Marie Sattler, Hanna A. Schniewind, Waldemar B. Minich, Christoph W. Haudum, Petra Niklowitz, Julia Muenzker, Gabor L. Kovacs, Thomas Reinehr, Barbara Obermayer-Pietsch, Lutz Schomburg
Summary: In European adult control groups and PCOS patients, only a very small fraction have natural GnRH-R-aAb. Our results do not support the hypothesis that GnRH-R is a significant autoantigen in PCOS.
Article
Medicine, General & Internal
Ying Liu, Xiao-Ya Ren, Ya-Guang Peng, Shao-Ke Chen, Xin-Ran Cheng, Miao Qin, Xiao-Ling Wang, Yan-Ning Song, Li-Jun Fan, Chun-Xiu Gong
Summary: The study demonstrated that hCG/hMG therapy is feasible and effective for treating male adolescents with CHH, with the initial 3 months of treatment showing the strongest effects. Results from the extended time-period also showed positive outcomes at the 1-year mark, indicating the potential of hCG/hMG regimen, although further research is needed to assess its long-term effectiveness and limitations.
CHINESE MEDICAL JOURNAL
(2021)
Article
Veterinary Sciences
Keisuke Kawase, Jumpei Tomiyasu, Kazuyuki Ban, Ryosuke Ono, Satoshi Ando, Aya Ono, Ran Kimura, Kanako Tomisawa, Motozumi Matsui, Shun-Ichi Shiihara
Summary: This study examined the efficacy of a commercial gonadotropin-releasing hormone vaccine as a contraceptive method in sexually matured female lions. Results showed that the vaccine successfully suppressed reproductive activity in lions for 246 days, suggesting it as a potential alternative contraceptive option.
JOURNAL OF VETERINARY MEDICAL SCIENCE
(2021)
Article
Agriculture, Dairy & Animal Science
M. H. C. Pereira, B. I. Cappellozza, R. L. A. Cerri, C. P. Sanches Jr, T. G. Guida, L. F. S. P. Barbosa, J. E. P. Santos, J. L. M. Vasconcelos
Summary: This study evaluated the use of a second PGF(2 alpha) treatment in improving pregnancy rates of lactating Holstein cows undergoing timed embryo transfer. The results showed that the use of a second PGF(2 alpha) treatment increased estrus expression and ovulation rates, but did not affect pregnancy rates.
JOURNAL OF DAIRY SCIENCE
(2023)
Article
Forestry
Myriam Cadotte, Julien H. Richard, Jean A. Berube, Steeve D. Cote
Summary: Research conducted on Anticosti Island in Canada revealed that white-tailed deer consume a large variety of fungal species, including up to 4979 different species. Female deer consumed a higher diversity of mushrooms compared to males, with a significant increase in mushroom consumption diversity among deer in 2015. Adult deer tended to consume a wider variety of mushrooms than juveniles.
Article
Forestry
Richard D. Sample, Zackary J. Delisle, Jameson M. Pierce, Robert K. Swihart, Joe N. Caudell, Michael A. Jenkins
Summary: Selection of woody species by white-tailed deer is influenced by deer densities, food availability, and landscape characteristics. Determining selection rankings across different regional landscapes is important for deer and forest management. This study developed selection rankings for 63 species within woodlots across Indiana and found that both woodlot and landscape-scale variables influenced deer's selection of browse species.
FOREST ECOLOGY AND MANAGEMENT
(2023)
Article
Neurosciences
Mattia Camera, Isabella Russo, Valentina Zamboni, Alessandra Ammoni, Simona Rando, Alessandro Morellato, Irene Cimino, Costanza Angelini, Paolo Giacobini, Roberto Oleari, Federica Amoruso, Anna Cariboni, Isabelle Franceschini, Emilia Turco, Paola Defilippi, Giorgio R. Merlo
Summary: The absence of the p140Cap gene in mice leads to abnormalities in fertility, puberty development, and hormone secretion. This may be due to its role in the development of the hypothalamic gonadotropic system and modulation of glutamatergic signaling.
FRONTIERS IN NEUROSCIENCE
(2022)