Review
Genetics & Heredity
Eva E. E. Lancaster, Dana M. M. Lapato, Roseann E. E. Peterson
Summary: Peripartum depression is a common mood disorder with limited research progress due to lack of disorder-specific studies, inadequate representation of global populations, and insufficient data. Large-scale population studies have the potential to accelerate scientific discovery, but challenges in data collection persist.
FRONTIERS IN GENETICS
(2022)
Article
Neurosciences
Jack E. Henningfield, Sherecce Fields, James C. Anthony, Lawrence S. Brown, Carlos A. Bolanos-Guzman, Sandra D. Comer, Richard De La Garza, Debra Furr-Holden, Albert Garcia-Romeu, Dorothy K. Hatsukami, Armin Raznahan, Carlos A. Zarate
Summary: Higher levels of excellence and innovation in research can be achieved by promoting equity, diversity, and inclusion in organizations. ACNP has made progress in increasing diversity, especially in female membership and leadership positions, but there is still room for improvement in areas like African American and other ethnic populations. Collaboration with other organizations committed to these goals may help accelerate progress towards fostering diversity and inclusion in scientific organizations.
NEUROPSYCHOPHARMACOLOGY
(2021)
Review
Agriculture, Dairy & Animal Science
Muhammad A. Arshad, Faiz-ul Hassan, Muhammad S. Rehman, Sharon A. Huws, Yanfen Cheng, Ahmad U. Din
Summary: Colonization and development of the gut microbiome play a key role in optimizing the health and performance of livestock animals, with dietary and management practices profoundly influencing the gut microbiota. Interventions during early life can establish a favorable microbiome, impacting nutrient utilization and immune response. Techniques like transgenesis and host genetics are being explored for their potential in modulating rumen microbiome and improving gut development and performance in neonatal ruminants.
Article
Multidisciplinary Sciences
Belen Vargas, Pablo Martinez, Scarlett Mac-Ginty, Tamara Hoffmann, Vania Martinez
Summary: This scoping review aims to identify and map the empirical literature on the implementation strategies and outcomes of school-based programs for adolescent suicide prevention (SBASP). School-based programs are preferred interventions for preventing suicide in adolescents, and their effectiveness has been well-systematized in several reviews. Implementation research is a growing field for prevention programs, making it possible to understand the nature of success or failure outcomes and maximize intervention benefits.
Review
Gastroenterology & Hepatology
Kosuke Mima, Tsuyoshi Hamada, Kentaro Inamura, Hideo Baba, Tomotaka Ugai, Shuji Ogino
Summary: There has been a significant increase in the incidence of early-onset cancers, particularly in the digestive system. While some of these cancers are associated with genetic variants, the majority are sporadic and multifactorial. Factors such as diets, lifestyle, environment, and the microbiome from early life to adulthood may play a role in the development of these cancers, but their exact contributions are still uncertain. To address this rising trend, interdisciplinary research approaches are needed to improve our understanding of the etiology and develop better prevention and treatment strategies.
Review
Medicine, General & Internal
Amy Azira Hamis, Ayuzeity Bistari Bukhori, Pei Pei Heng, Miaw Yn Jane Ling, Muhammad Al-Amin Shaharuddin, Nazmeen Adline Fawwazah Fauzi, Noor Azreen Masdor, Rahayu Othman, Aniza Ismail
Summary: This scoping review aimed to consolidate all recent evidence on COVID-19 field hospital implementation approaches, challenges and potentialities. The study found that surge capacity was an important consideration in the implementation strategies, and the management of field hospitals faced challenges such as staff and resource shortages, inability to anticipate patient load, and poor communication. The findings also highlighted opportunities and recommendations for improvement in field hospital management.
Article
Genetics & Heredity
Jane M. Tiller, Andrew Bakshi, Adam R. Brotchie, Robert C. Green, Ingrid M. Winship, Paul Lacaze
Summary: This study investigates public attitudes and willingness to participate in DNA screening in Australia. The majority of respondents express willingness to participate, with a preference for screening in early adulthood. Concerns about privacy and insurance implications decrease the likelihood of participation.
JOURNAL OF MEDICAL GENETICS
(2023)
Review
Ecology
Courtney L. Davis, Robert P. Guralnick, Elise F. Zipkin
Summary: Natural history collections provide valuable information for understanding the impact of global change on biodiversity. However, using museum records to track long-term insect population trends poses challenges due to spatiotemporal biases and data sparsity. Recent advancements in methodology and integrated modeling offer opportunities to overcome these challenges and accurately estimate population trends.
JOURNAL OF ANIMAL ECOLOGY
(2023)
Review
Virology
Ted Ling-Hu, Estefany Rios-Guzman, Ramon Lorenzo-Redondo, Egon A. A. Ozer, Judd F. F. Hultquist
Summary: Global SARS-CoV-2 genomic surveillance efforts provide critical data for clinical care and public health, but current limitations in each step of the surveillance pipeline compromise its effectiveness. These limitations include biases in sampling methods, lack of standardization in genotyping strategies and data processing, limitations and inconsistencies in clinical and demographic data collection, and delays in implementing genomic surveillance data in public health.
Article
Social Sciences, Interdisciplinary
Lynn Frewer, Max Blanck, Stephan Bronzwaer, Laura Martino, Domagoj Vrbos, Yann Devos
Summary: This report summarises the main discussions, conclusions and recommendations of the 'One Society' track of the 'ONE - Health, Environment & Society - Conference 2022', which emphasised the importance of collaboration and co-production in understanding food safety risks within the 'One Health' context. It highlighted the need for an EU collaborative knowledge ecosystem, audience-focused participatory approaches, and dedicated resources for research project collaborations. It also stressed the significance of implementing open science practices and making them a default principle in regulatory science.
JOURNAL OF RISK RESEARCH
(2023)
Review
Public, Environmental & Occupational Health
Mona Alhasani, Dinesh Mulchandani, Oladapo Oyebode, Nilufar Baghaei, Rita Orji
Summary: This study reviews 150 stress management apps and finds that the most frequently employed strategies are personalization, self-monitoring, and trustworthiness, while social support strategies such as competition, cooperation, and social comparison are the least employed. The study also compares the findings within the stress management domain with those from other mental health domains and offers eight design recommendations.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Immunology
Jarred McAteer, Gordana Derado, Michael Hughes, Amelia Bhatnagar, Felicita Medalla, Kevin Chatham-Stevens, Grace D. Appiah, Eric Mintz
Summary: Typhoid fever in the United States is mainly acquired through international travel by unvaccinated individuals, with no vaccine licensed for children <2 years old. A high proportion of pediatric travelers eligible for vaccination were unvaccinated, and antimicrobial-resistant infections were common. New public health strategies are needed to improve vaccine coverage and prevent drug-resistant infections.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Health Care Sciences & Services
Leonard E. Egede, Rebekah J. Walker, Aprill Z. Dawson, Joni S. Williams, Jennifer A. Campbell, Mukoso N. Ozieh, Anna Palatnik
Summary: Our multidisciplinary research team, comprising 6 faculty and 36 program staff, worked diligently to address the impact of COVID-19 on the ethnic minority population in inner-city Milwaukee, navigating challenges, making difficult decisions, and responding to community needs with the goal of informing policy and facilitating lasting change.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2021)
Article
Public, Environmental & Occupational Health
Robert W. Armstrong, Michaela Mantel, Gijs Walraven, Lukoye Atwoli, Anthony K. Ngugi
Summary: Health sciences curricular planners are facing challenges in adding new content to established education programs, particularly in areas such as public health, health systems, global health, and planetary health. A convergence model is proposed to build a common framework for students to integrate and align knowledge to individual clients or patients. This framework includes five areas that influence health and wellbeing, as well as methodologies essential to understanding health at both individual and population levels.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Genetics & Heredity
Charleston W. K. Chiang
Summary: There is a recognized need to include diverse populations in genetic studies, but obstacles such as difficulty in recruitment and lack of representation in genomic references persist. Studying multiple diverse populations can provide insightful, population-specific insights. By developing genomic resources and integrating evolutionary thinking, we can improve understanding of genetic risk factors, reduce health disparities, and enhance healthcare for underserved populations.
FRONTIERS IN GENETICS
(2021)
Article
Psychology, Clinical
Wendy S. Slutske, Leah S. Richmond-Rakerd, Thomas M. Piasecki, Sandhya Ramrakha, Richie Poulton, Terrie E. Moffitt, Avshalom Caspi
Summary: This study found that childhood precursors (social class, general intelligence, self-control) predicted lifelong disordered gambling, which in turn predicted negative outcomes in adulthood. Adjusting for childhood precursors weakened these associations.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Public, Environmental & Occupational Health
Kyle J. Bourassa, Terrie E. Moffitt, HonaLee Harrington, Renate Houts, Richie Poulton, Sandhya Ramrakha, Line J. H. Rasmussen, Jasmin Wertz, Avshalom Caspi
Summary: Adverse childhood experiences (ACEs) are associated with poorer health in midlife, and psychosocial factors play an important role in this association. Stressful life events, perceived stress, negative emotionality, and health behaviors mediate the relationship between childhood ACEs and health outcomes in middle-aged adults. Public health efforts can focus on reducing stressful life events, negative emotionality, perceived stress, and improving health behaviors to mitigate the health consequences of ACEs.
PREVENTION SCIENCE
(2023)
Review
Cell Biology
Erica C. Lorenzo, George A. Kuchel, Chia-Ling Kuo, Terrie E. Moffitt, Breno S. Diniz
Summary: Major depressive disorder (MDD) is associated with an increased risk of age-related adverse outcomes, possibly due to the overlap between biological abnormalities in MDD and biological changes associated with aging. Exploring the intersection between aging and MDD and using geroscience-guided interventions, such as senolytics, could potentially delay or improve MDD by targeting aging.
AGEING RESEARCH REVIEWS
(2023)
Article
Neurosciences
Ethan T. Whitman, Annchen R. Knodt, Maxwell L. Elliott, Wickliffe C. Abraham, Kirsten Cheyne, Sean Hogan, David Ireland, Ross Keenan, Joan H. Leung, Tracy R. Melzer, Richie Poulton, Suzanne C. Purdy, Sandhya Ramrakha, Peter R. Thorne, Avshalom Caspi, Terrie E. Moffitt, Ahmad R. Hariri
Summary: Although higher-order cognitive and lower-order sensorimotor abilities are generally regarded as distinct and studied separately, there is evidence that they not only covary but also that this covariation increases across the lifespan. This pattern has been leveraged in clinical settings where a simple assessment of sensory or motor ability can forecast age-related cognitive decline and risk for dementia. However, the brain mechanisms underlying cognitive, sensory, and motor covariation are largely unknown.
Article
Geriatrics & Gerontology
Aline Thomas, Daniel W. Belsky, Yian Gu
Summary: This study analyzed data from 42,625 participants and found that a balanced diet and more physical activity are associated with the slowing of biological aging. The results showed that individuals who adhered to a Mediterranean diet and engaged in more leisure time physical activity had younger biological ages compared to those with unhealthy lifestyles.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Geriatrics & Gerontology
Karen Sugden, Terrie E. Moffitt, Thalida Em Arpawong, Louise Arseneault, Daniel W. Belsky, David L. Corcoran, Eileen M. Crimmins, Eilis Hannon, Renate Houts, Jonathan S. Mill, Richie Poulton, Sandhya Ramrakha, Jasmin Wertz, Benjamin S. Williams, Avshalom Caspi
Summary: Individuals with higher education have a slower pace of aging and a lower risk of age-related diseases, regardless of genetic factors.
JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES
(2023)
Article
Behavioral Sciences
Richie Poulton, Avshalom Caspi, Terrie E. Moffitt
Summary: Four lines of research from the 'Dunedin Study', a 50-year investigation on anxiety, were reviewed. The findings include: (i) Evolutionarily-relevant childhood fears may have different pathways compared to evolutionarily-neutral fears. (ii) Sequential comorbidity within and outside the family of disorders is common, emphasizing the importance of developmental history. (iii) The relationship between GAD and MDE is more symmetric than previously assumed. (iv) PTSD in adulthood is influenced by childhood risk factors, sequential comorbidity, high-stress life events, and mental disorder history. The implications for epidemiology, nosology, developmental history, and prevention/treatment options are discussed.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2023)
Article
Psychology, Clinical
Line C. Gjerde, Espen Moen Eilertsen, Tom A. McAdams, Rosa Cheesman, Terrie E. Moffitt, Avshalom Caspi, Thalia C. Eley, Espen Roysamb, Tom H. Rosenstrom, Eivind Ystrom
Summary: This study investigated the joint factor structure of psychopathology and personality in eight-year-old children. The results showed that correlations between normative and pathological traits mostly reflect one heritable and psychometrically interpretable factor. Furthermore, the association between the factor and low gestational age indicates the need for further study of early developmental mechanisms.
PSYCHOLOGICAL MEDICINE
(2023)
Correction
Psychology, Clinical
Line C. Gjerde, Espen Moen Eilertsen, Tom A. McAdams, Rosa Cheesman, Terrie E. Moffitt, Avshalom Caspi, Thalia C. Eley, Espen Roysamb, Tom H. Rosenstroem, Eivind Ystrom
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychiatry
Joanne B. Newbury, Louise Arseneault, Terrie E. Moffitt, Candice L. Odgers, Laura D. Howe, Ioannis Bakolis, Aaron Reuben, Andrea Danese, Karen Sugden, Benjamin Williams, Line J. H. Rasmussen, Antonella Trotta, Antony P. Ambler, Helen L. Fisher
Summary: Children exposed to socioenvironmental adversities are more likely to develop subclinical psychotic experiences during adolescence. This association is partly explained by cognitive ability and inflammation.
SCHIZOPHRENIA BULLETIN
(2023)
Article
Clinical Neurology
Juan J. Madrid-Valero, Timothy Matthews, Nicola L. Barclay, Candice L. Odgers, Terrie E. Moffitt, Avshalom Caspi, Louise Arseneault, Alice M. Gregory
Summary: Research findings on the association between digital technology use and poor sleep quality in adolescence and young adulthood have been mixed. This study used a genetically informative twin design to investigate this association, finding that adolescents' perceived problematic use of technology is associated with poor sleep quality, even after controlling for familial factors. The study also revealed a substantial genetic correlation between problematic use of technology and sleep quality.
Article
Multidisciplinary Sciences
Xu Gao, Tong Geng, Meijie Jiang, Ninghao Huang, Yinan Zheng, Daniel W. Belsky, Tao Huang
Summary: Theory suggests that advanced biological aging is a potential risk factor for incident depression/anxiety in midlife and older adults. It could serve as a target for risk assessment and intervention.
NATURE COMMUNICATIONS
(2023)
Article
Gerontology
Yang C. Yang, Christine E. Walsh, Kaitlin Shartle, Rebecca C. Stebbins, Allison E. Aiello, Daniel W. Belsky, Kathleen Mullan Harris, Marianne Chanti-Ketterl, Brenda L. Plassman
Summary: This study fills gaps in research on cognitive decline and social disparities related to aging, Alzheimer's disease, and dementia. By analyzing data from four large longitudinal studies spanning two decades, we found that cognitive decline begins in the 4th decade of life, gender differences in decline vary with age, and there are persistent disadvantages among non-Hispanic Blacks, Hispanics, and those with no college education. We also observed improvement in cognitive function among cohorts born in the 20th century, but widening social inequalities in more recent cohorts.
JOURNAL OF AGING AND HEALTH
(2023)
Correction
Multidisciplinary Sciences
Xu Gao, Tong Geng, Meijie Jiang, Ninghao Huang, Yinan Zheng, Daniel W. Belsky, Tao Huang
NATURE COMMUNICATIONS
(2023)
