The Statin–Iron Nexus: Anti-Inflammatory Intervention for Arterial Disease Prevention

Statin Use and Risk of Diabetes Mellitus in Postmenopausal Women in the Women's Health Initiative

(2012) Annie L. Culver   ARCHIVES OF INTERNAL MEDICINE

Hepcidin Destabilizes Atherosclerotic Plaque Via Overactivating Macrophages After Erythrophagocytosis

(2012) Jing Jing Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Three Reasons to Abandon Low-Density Lipoprotein Targets

(2012) Rodney A. Hayward et al.  

Body iron stores and risk of type 2 diabetes: results from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam study

(2012) J. Montonen et al.   DIABETOLOGIA

Is Universal Pediatric Lipid Screening Justified?

(2012) Matthew W. Gillman et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Might the beneficial effects of statin drugs be related to their action on iron metabolism?

(2012) L. Mascitelli et al.   QJM-AN INTERNATIONAL JOURNAL OF MEDICINE

Effect of controlled reduction of body iron stores on clinical outcomes in peripheral arterial disease

(2011) Leo R. Zacharski et al.   AMERICAN HEART JOURNAL

Dose-related Effect of Statins in Venous Thrombosis Risk Reduction

(2011) Danai Khemasuwan et al.   AMERICAN JOURNAL OF MEDICINE

Dietary Supplements and Mortality Rate in Older Women

(2011) Jaakko Mursu   ARCHIVES OF INTERNAL MEDICINE

Pharmacological Suppression of Hepcidin Increases Macrophage Cholesterol Efflux and Reduces Foam Cell Formation and Atherosclerosis

(2011) Omar Saeed et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Clinical Benefit of Statin Pretreatment in Patients Undergoing Percutaneous Coronary Intervention

(2011) Giuseppe Patti et al.   CIRCULATION

Using Stress Testing to Guide Primary Prevention of Coronary Heart Disease Among Intermediate-Risk Patients

(2011) Benjamin Z. Galper et al.   CIRCULATION

Total Mortality by Transferrin Saturation Levels: Two General Population Studies and a Metaanalysis

(2011) C. Ellervik et al.   CLINICAL CHEMISTRY

Lipid-lowering therapy and coronary artery bypass graft surgery

(2011) Alexander Kulik et al.   CURRENT OPINION IN CARDIOLOGY

Mechanisms for the anti-inflammatory effects of statins

(2011) De-xiu Bu et al.   CURRENT OPINION IN LIPIDOLOGY

High-sensitivity C-reactive protein, statin therapy, and risks of atrial fibrillation: an exploratory analysis of the JUPITER trial

(2011) J. M. Pena et al.   EUROPEAN HEART JOURNAL

Rosuvastatin Blocks Advanced Glycation End Products-elicited Reduction of Macrophage Cholesterol Efflux by Suppressing NADPH Oxidase Activity via Inhibition of Geranylgeranylation of Rac-1

(2011) Y. Ishibashi et al.   HORMONE AND METABOLIC RESEARCH

Long-term Efficacy of Upstream Therapy With Lipophilic or Hydrophilic Statins on Antiarrhythmic Drugs in Patients With Paroxysmal Atrial Fibrillation

(2011) Takashi Komatsu et al.   International Heart Journal

Universal Screening and Drug Treatment of Dyslipidemia in Children and Adolescents

(2011) Bruce M. Psaty et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Inhibitory effects of iron on bone morphogenetic protein 2-induced osteoblastogenesis

(2011) Qing Yang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Atorvastatin activates heme oxygenase-1 at the stress response elements

(2011) Simon C.M. Kwok et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Simvastatin reduces atherogenesis and promotes the expression of hepatic genes associated with reverse cholesterol transport in apoE-knockout mice fed high-fat diet

(2011) Guohua Song et al.   Lipids in Health and Disease

Prevalence and risk factors of muscle complications secondary to statins

(2011) Khalid El-Salem et al.   MUSCLE & NERVE

Cholesterol Efflux Capacity, High-Density Lipoprotein Function, and Atherosclerosis

(2011) Amit V. Khera et al.   NEW ENGLAND JOURNAL OF MEDICINE

Statins Promote the Regression of Atherosclerosis via Activation of the CCR7-Dependent Emigration Pathway in Macrophages

(2011) Jonathan E. Feig et al.   PLoS One

Writing a narrative biomedical review: considerations for authors, peer reviewers, and editors

(2011) Armen Yuri Gasparyan et al.   RHEUMATOLOGY INTERNATIONAL

Statins in the prevention of venous thromboembolism: A meta-analysis of observational studies

(2011) Menaka Pai et al.   THROMBOSIS RESEARCH

Simvastatin inhibits pro-inflammatory mediators through induction of heme oxygenase-1 expression in lipopolysaccharide-stimulated RAW264.7 macrophages

(2011) Pak-On Leung et al.   TOXICOLOGY LETTERS

Simvastatin induces the expression of hemeoxygenase-1 against ischemia–reperfusion injury on the testes in rats

(2011) Yuan-Po Tu et al.   TOXICOLOGY LETTERS

Impact of Chronic Pre-Treatment of Statins on the Level of Systemic Inflammation and Myocardial Perfusion in Patients Undergoing Primary Angioplasty

(2010) Vecih Oduncu et al.   AMERICAN JOURNAL OF CARDIOLOGY

Serum Hepcidin and Macrophage Iron Correlate With MCP-1 Release and Vascular Damage in Patients With Metabolic Syndrome Alterations

(2010) Luca Valenti et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Simvastatin-dependent up-regulation of heme oxygenase-1 via mRNA stabilization in human endothelial cells

(2010) Urte Hinkelmann et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Remission of paroxysmal atrial fibrillation with iron reduction in haemophilia A

(2010) L. R. ZACHARSKI et al.   HAEMOPHILIA

Metals in air pollution particles decrease whole-blood coagulation time

(2010) Rahul G. Sangani et al.   INHALATION TOXICOLOGY

Iron Status Is Associated with Carotid Atherosclerotic Plaques in Middle-Aged Adults

(2010) Namanjeet Ahluwalia et al.   JOURNAL OF NUTRITION

Regarding “Statins, heme oxygenase-1, iron, and atherosclerosis”

(2010) Jerome L. Sullivan   JOURNAL OF VASCULAR SURGERY

Ferritin levels, inflammatory biomarkers, and mortality in peripheral arterial disease: A substudy of the Iron (Fe) and Atherosclerosis Study (FeAST) Trial

(2010) Ralph G. DePalma et al.   JOURNAL OF VASCULAR SURGERY

Effect of phlebotomy on lipid metabolism in subjects with hereditary hemochromatosis

(2010) Paola Casanova-Esteban et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

One-Year Treatment with Rosuvastatin Reduces Intima-Media Thickness in 45 Hypercholesterolemic Subjects with Asymptomatic Carotid Artery Disease

(2010) Graziano Riccioni et al.   PHARMACOLOGY

Effects of alcohol consumption on iron metabolism

(2010) M. Lieb et al.   AMERICAN JOURNAL OF DRUG AND ALCOHOL ABUSE

Iron and Menopause: Does Increased Iron Affect the Health of Postmenopausal Women?

(2009) Jinlong Jian et al.   ANTIOXIDANTS & REDOX SIGNALING

Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases

(2009) Douglas B Kell   BMC Medical Genomics

Anti-atherogenic effect of statins: role of nitric oxide, peroxynitrite and haem oxygenase-1

(2009) G Heeba et al.   BRITISH JOURNAL OF PHARMACOLOGY

Heme Oxygenase 1 Determines Atherosclerotic Lesion Progression Into a Vulnerable Plaque

(2009) Caroline Cheng et al.   CIRCULATION

Mediterranean Diet and Incidence of and Mortality From Coronary Heart Disease and Stroke in Women

(2009) Teresa T. Fung et al.   CIRCULATION

Do Hemochromatosis Mutations Protect Against Iron-Mediated Atherogenesis?

(2009) Jerome L. Sullivan   Circulation-Cardiovascular Genetics

Frequency and Clinical Relevance of Drug Interactions with Lovastatin and Simvastatin

(2009) Tuire Tirkkonen et al.   DRUG SAFETY

Regulatory effects of ferritin on angiogenesis

(2009) L. G. Coffman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rosuvastatin reduces atherosclerotic lesions and promotes progenitor cell mobilisation and recruitment in apolipoprotein E knockout mice

(2008) Marco R. Schroeter et al.   ATHEROSCLEROSIS

As Macrophages Indulge, Atherosclerotic Lesions Bulge

(2008) Alan Daugherty et al.   CIRCULATION RESEARCH

Effect of fluvastatin on serum prohepcidin levels in patients with end-stage renal disease

(2008) Mahmut Arabul et al.   CLINICAL BIOCHEMISTRY

Iron Involvement in Multiple Signaling Pathways of Atherosclerosis: A Revisited Hypothesis

(2008) Xi-Ming Yuan et al.   CURRENT MEDICINAL CHEMISTRY

Intensive Lipid-lowering Therapy Ameliorates Novel Calcification Markers and GSM Score in Patients with Carotid Stenosis

(2008) N.P.E. Kadoglou et al.   EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY

The Effect of Atorvastatin in Patients with Polycystic Ovary Syndrome: A Randomized Double-Blind Placebo-Controlled Study

(2008) Thozhukat Sathyapalan et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The Influence of Pravastatin and Atorvastatin on Markers of Oxidative Stress in Hypercholesterolemic Humans

(2008) Bonnie Ky et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Decreased Cancer Risk After Iron Reduction in Patients With Peripheral Arterial Disease: Results From a Randomized Trial

(2008) L. R. Zacharski et al.   JNCI-Journal of the National Cancer Institute

Rosuvastatin to Prevent Vascular Events in Men and Women with Elevated C-Reactive Protein

(2008) Paul M Ridker et al.   NEW ENGLAND JOURNAL OF MEDICINE