Article
Psychiatry
Leah H. Rubin, Jiaxu Han, Jennifer M. Coughlin, S. Kristian Hill, Jeffrey R. Bishop, Carol A. Tamminga, Brett A. Clementz, Godfrey D. Pearlson, Matcheri S. Keshavan, Elliot S. Gershon, Keri J. Heilman, Stephen W. Porges, John A. Sweeney, Sarah Keedy
Summary: Affective and non-affective psychotic disorders are associated with varying levels of impairment in affective processing, and this study compared performance on a dynamic facial expression identification task in individuals with psychotic disorders and healthy controls. Results showed differences in accuracy and speed of emotion identification across groups, with certain biotypes demonstrating more severe deficits in emotion recognition. These findings contribute to our understanding of social and emotional deficits in the psychosis spectrum.
SCHIZOPHRENIA RESEARCH
(2022)
Article
Clinical Neurology
David J. Miklowitz, Marc J. Weintraub, Filippo Posta, Patricia D. Walshaw, Samantha J. Frey, Georga M. Morgan-Fleming, Catherine A. Wilkerson, Danielle M. Denenny, Armen A. Arevian
Summary: Integrating psychosocial interventions with mobile apps may increase treatment engagement among adolescents. The mobile-enhanced family-focused therapy showed significant improvement in adolescents' depression scores and reductions in perceived criticism expressed by parents.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Clinical Neurology
M. Maziade, A. Bureau, V Jomphe, A. M. Gagne
Summary: The study found that ERG anomalies in high-risk youths are associated with psychotic-like experiences, lower global IQ, and deteriorated global functioning. These results may provide clues for clinicians to monitor differences in children from high-risk families.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2022)
Article
Clinical Neurology
Luis R. Patino, Maxwell J. Tallman, Hongbo Wen, Caleb M. Adler, Jeffrey A. Welge, Melissa P. DelBello
Summary: The objective of this study was to evaluate differences in sustained attention and associated neurofunctional profiles between bipolar disorder type I, attention-deficit/hyperactivity disorder, and healthy comparison youth. Adolescent participants underwent MRI while completing a modified Continuous Performance Task. BD participants displayed deficits in sustained attention and lower activation in brain regions associated with performance and neural integration. These differences were distinct to the BD group and not attributable to ADHD comorbidity.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Psychiatry
Wang Xiao, Gu Manyi, Ali Khaleghi
Summary: In this study, the patterns of steady-state visual evoked potentials (SSVEP) and auditory steady-state response (ASSR) were assessed in adolescents with bipolar disorder (BD). The results showed impairments in motor control inhibition task, increased SSVEP amplitude and phase in the frontal region, and decreased ASSR amplitude in the prefrontal region and increased ASSR amplitude in the right-frontal and centro-parietal areas in BD patients compared to healthy adolescents. These findings suggest abnormalities in visual and auditory pathways in BD.
JOURNAL OF PSYCHIATRIC RESEARCH
(2022)
Article
Clinical Neurology
Nicole R. Wong, Kayla E. Carta, Marc J. Weintraub, David J. Miklowitz
Summary: Family-focused therapy (FFT) is associated with longer intervals between mood episodes and reductions in suicidal ideation among adolescents at risk for bipolar disorders. Therapeutic alliance between adolescents/parents and their therapists is correlated with symptomatic outcomes of adolescents over 18 weeks. Enhancing adolescents' engagement in therapy may strengthen the long-term effects of family interventions.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Clinical Neurology
Ta-Chuan Yeh, Mu-Hong Chen, Ya-Mei Bai, Shih-Jen Tsai, Ju-Wei Hsu, Kai-Lin Huang, Tung-Ping Su, Tzeng-Ji Chen, Chih-Sung Liang
Summary: This large-scale longitudinal study using the Taiwan National Health Insurance Research Database found that children and adolescents with ASD are more likely to be diagnosed with anxiety disorder in late childhood, and with schizophrenia, bipolar disorder, depressive disorder, and OCD in adolescence.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Review
Clinical Neurology
Lisa S. Furlong, Susan L. Rossell, Georgia F. Caruana, Vanessa L. Cropley, Matthew Hughes, Tamsyn E. Van Rheenen
Summary: The review found abnormalities in both the activity and connectivity of facial emotion processing neural circuitry in individuals with bipolar disorder, which may contribute to social cognitive impairments. Future research should further investigate the connectivity and spatiotemporal course of these neural events.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Psychology, Developmental
Akua F. Nimarko, Adina S. Fischer, Kelsey E. Hagan, Aaron J. Gorelik, Yvonne Lu, Caroline J. Young, Manpreet K. Singh
Summary: Adolescents at risk for familial bipolar disorder and major depressive disorder show significant neural differences in activation and connectivity during positive emotion processing, particularly in the activation and connectivity of the putamen. These differences may potentially serve as markers of vulnerability for the development of mood or anxiety disorders.
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
(2021)
Article
Psychology, Developmental
Han-Sian Yang, Ju-Wei Hsu, Kai-Lin Huang, Shih-Jen Tsai, Ya-Mei Bai, Tung-Ping Su, Tzeng-Ji Chen, Mu-Hong Chen
Summary: Teenage pregnancy is a significant public health issue, and there is an association between bipolar disorder and early pregnancy. However, bipolar disorder medications may reduce the risk of early pregnancy.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2023)
Article
Psychiatry
Li-jun Wang, Tian-hua Cheng, Jia-sen Geng, Juan Yang, Chang Liu, Guo-hui Zhu, Jia-cheng Luo, Gui-zhen Wang, Xiang He Zhu, Yi Wang, Jia Huang, Yan-yu Wang
Summary: This study compares the differences in facial emotion recognition abilities in patients with schizophrenia, major depressive disorder, and bipolar disorder under different social interaction situations. The results show that all three groups of patients are slower in recognizing anger emotion in the praise situation compared to healthy controls. In the inquiry situation, patients with schizophrenia recognize angry faces faster than those with major depressive disorder and bipolar disorder. These findings may be beneficial for early screening and precise intervention for these mental disorders.
ASIAN JOURNAL OF PSYCHIATRY
(2023)
Review
Clinical Neurology
Gin S. Malhi, Maedeh Jadidi, Erica Bell
Summary: This article examines the ongoing debate on the diagnosis of bipolar disorder in children and adolescents. The lack of consensus in the field has hindered progress in understanding the true prevalence of pediatric bipolar disorder. The article proposes a solution to break this deadlock.
Article
Clinical Neurology
Hu Deng, Fang Wen, Hui Xu, Hanxue Yang, Junjuan Yan, Yi Zheng, Yonghua Cui, Ying Li
Summary: This study is the first nationwide survey on the prevalence of affective disorders among school-attending children and adolescents aged 6-16 in China. The results showed that the total prevalence of affective disorders was 3.212%, with higher rates among females than males and among adolescents compared to children.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Clinical Neurology
Anna Krogh Andreassen, Rikke Lambek, Nicoline Hemager, Christina Bruun Knudsen, Lotte Veddum, Anders Helles Carlsen, Anette Faurskov Bundgaard, Anne Sondergaard, Julie Marie Brandt, Maja Gregersen, Mette Falkenberg Krantz, Birgitte Klee Burton, Jens Richardt Mollegaard Jepsen, Anne Amalie Elgaard Thorup, Merete Nordentoft, Ole Mors, Vibeke Fuglsang Bliksted, Aja Greve
Summary: Despite genetic overlap, working memory impairments are mainly found in children of parents with schizophrenia. Using a data-driven approach, researchers found that a subset of children at familial high risk of schizophrenia or bipolar disorder exhibited persistent working memory impairments throughout middle childhood, which may serve as a vulnerability marker of transition to severe mental illness.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Psychology, Experimental
Dolichan Kollareth, Juan Duran, Yiran Ma, Kelly S. Pierce, Hiram Brownell, James A. Russell
Summary: This article examines people's ability to predict facial expressions in different language backgrounds and finds that the majority of respondents are unable to choose the correct label for most of the 12 facial expressions, indicating a low recognition rate for the predicted emotions.
JOURNAL OF EXPERIMENTAL PSYCHOLOGY-GENERAL
(2023)
Article
Psychology, Developmental
Simone P. Haller, Joel Stoddard, Christian Botz-Zapp, Michal Clayton, Caroline MacGillivray, Gretchen Perhamus, Kelsey Stiles, Katharina Kircanski, Ian S. Penton-Voak, Yair Bar-Haim, Marcus Munafo, Kenneth E. Towbin, Melissa A. Brotman
Summary: The study aimed to examine the effect of interpretation bias training on youths with chronic irritability. While engaging the proposed behavioral target, there was no statistically significant improvement in clinical outcomes.
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
(2022)
Article
Psychology, Developmental
Jodi Zik, Christen M. Deveney, Jarrod M. Ellingson, Simone P. Haller, Katharina Kircanski, Elise M. Cardinale, Melissa A. Brotman, Joel Stoddard
Summary: Despite being distinct from aggression, irritability is highly correlated with anger. Child-reported outward expression of anger overlaps significantly with irritability, providing empirical support for the clinical categorization of irritability as a proneness to express anger outwardly. The informant source explains a substantial portion of response variance.
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
(2022)
Article
Psychology, Clinical
Maria K. Wilson, Danielle Cornacchio, Melissa A. Brotman, Jonathan S. Comer
Summary: In this age range, ARI-P scores showed large associations with other irritability index and small-to-large associations with aggression, anxiety, depression, and attention problems, supporting the convergent and concurrent validity of the ARI-P when used with children in this younger age range.
Article
Neurosciences
Gang Chen, Daniel S. Pine, Melissa A. Brotman, Ashley R. Smith, Robert W. Cox, Paul A. Taylor, Simone P. Haller
Summary: Trials play a crucial role in task-based neuroimaging, impacting statistical efficiency and condition-level generalizability. Increasing both trial and subject sample sizes can improve statistical efficiency more effectively than focusing on subjects alone, and trial-level modeling may be necessary for accurately assessing effect estimates with small trial size.
Article
Psychology, Developmental
Sanjana Ravi, Mazneen Havewala, Katharina Kircanski, Melissa A. Brotman, Leslie Schneider, Kathryn Degnan, Alisa Almas, Nathan Fox, Daniel S. Pine, Ellen Leibenluft, Courtney Filippi
Summary: Prolonged irritability in childhood may predict later psychopathology, and negative parenting behaviors may moderate the developmental trajectory of childhood irritability. Negative emotion socialization and control behaviors of parents significantly influence irritability.
DEVELOPMENT AND PSYCHOPATHOLOGY
(2022)
Editorial Material
Psychology, Developmental
Melissa A. Brotman, Katharina Kircanski
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
(2023)
Review
Psychology, Developmental
Ka Shu Lee, Cheyanne N. Hagan, Mina Hughes, Grace Cotter, Eva McAdam Freud, Katharina Kircanski, Ellen Leibenluft, Melissa A. Brotman, Wan-Ling Tseng
Summary: This study aims to summarize the methods and results of using functional magnetic resonance imaging (fMRI) to investigate neural dysfunction in childhood irritability. The findings showed small sample sizes, heterogeneous sample characteristics, and a lack of neural activation convergence. Therefore, there is a need for standardized irritability assessments and more homogeneous fMRI tasks to study the neural mechanisms of irritability.
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
(2023)
Article
Family Studies
Christopher J. Senior, Sheina A. Godovich, Nina D. Shiffrin, Colleen M. Cummings, Mary K. Alvord, Brendan A. Rich
Summary: Twenty percent of youth experience psychiatric illness before adulthood, but most of them do not receive adequate mental health services. Youth of color, who are more likely to face adversity, stress, and barriers to treatment, are particularly vulnerable. Schools can play a key role in addressing these barriers and disparities. This study found that a school-based psychotherapy intervention, the Resilience Builder Program (RBP), was effective in improving behavioral, social, emotional, and executive functioning domains for underserved youth. It also showed promise in improving emotional regulation, suggesting the potential for its universal application in classroom settings.
JOURNAL OF CHILD AND FAMILY STUDIES
(2023)
Review
Psychology, Developmental
Alecia C. Vogel, Melissa A. Brotman, Amy Krain Roy, Susan B. Perlman
Summary: This study highlights the importance of studying positive emotion dysregulation and proposes a developmental approach to examining it within the context of temperament. The research findings suggest that dysregulation of positive emotion is associated with externalizing symptoms and clinical impairment in youth.
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
(2023)
Article
Family Studies
Simone Chad-Friedman, Colleen M. Cummings, Nina D. Shiffrin, Mary K. Alvord, Brendan A. Rich
Summary: The study examines the impact of self-esteem, social support, and self-efficacy on the effectiveness of cognitive behavioral therapy for children. The results suggest that these factors play a particularly important role in enhancing treatment response for children from diverse racial/ethnic and socioeconomic backgrounds.
JOURNAL OF CHILD AND FAMILY STUDIES
(2023)
Editorial Material
Psychology, Developmental
Douglas K. Novins, Robert R. Althoff, Melissa A. Brotman, Samuele Cortese, Melissa DelBello, Alysa Doyle, Stacy S. Drury, Lisa Fortuna, Jean A. Frazier, Mary Fristad, Schuyler W. Henderson, Elizabeth McCauley, Christel Middeldorp, Wanjiku F. M. Njoroge, Cynthia E. Rogers, Tonya White
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
(2023)
Article
Psychology, Developmental
Wan-Ling Tseng, Reut Naim, Amanda Chue, Shannon Shaughnessy, Jennifer Meigs, Daniel S. Pine, Ellen Leibenluft, Katharina Kircanski, Melissa A. Brotman
Summary: This study used a network analytic approach and smartphone-based ecological momentary assessment to investigate the relationship between irritability and other anxiety and mood symptoms. The results showed that frustration was the most central node in the networks of between-prompt symptoms, while sadness and anger were the most central nodes in the networks of momentary symptoms. Furthermore, anger was broadly positively related to sadness, mood lability, and worry across individuals.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2023)
Meeting Abstract
Neurosciences
Isaac Morales, Olufunmilayo Telli, Kyunghun Lee, Ramaris German, Katharina Kircanski, Melissa A. Brotman, Ellen Leibenluft, Daniel Pine, Elise Cardinale
BIOLOGICAL PSYCHIATRY
(2022)
Meeting Abstract
Neurosciences
Reut Naim, Shannon Shaughnessy, Ashley Smith, Katharina Kircanski, Melissa A. Brotman
BIOLOGICAL PSYCHIATRY
(2022)
Meeting Abstract
Neurosciences
Theodore Doykos, Matt Jones, Simone Haller, Melissa A. Brotman, Joel Stoddard
BIOLOGICAL PSYCHIATRY
(2022)