Caffeine promotes glutamate and histamine release in the posterior hypothalamus

Lack of Hypocretin Attenuates Behavioral Changes Produced by Glutamatergic Activation of the Perifornical-Lateral Hypothalamic Area

(2014) Andrey Kostin et al.   SLEEP

Greatly increased numbers of histamine cells in human narcolepsy with cataplexy

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Optogenetic Stimulation of MCH Neurons Increases Sleep

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Human hypocretin and melanin-concentrating hormone levels are linked to emotion and social interaction

(2013) Ashley M. Blouin et al.   Nature Communications

Caffeine counteracts impairments in task-oriented psychomotor performance induced by chlorpheniramine: a double-blind placebo-controlled crossover study

(2012) Sung-Wan Kim et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Arousal Effect of Caffeine Depends on Adenosine A2A Receptors in the Shell of the Nucleus Accumbens

(2011) M. Lazarus et al.   JOURNAL OF NEUROSCIENCE

Long-Term Homeostasis of Extracellular Glutamate in the Rat Cerebral Cortex across Sleep and Waking States

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Characterisation of the effects of caffeine on sleep in the rat: a potential model of sleep disruption

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Rapid changes in glutamate levels in the posterior hypothalamus across sleep-wake states in freely behaving rats

(2008) Joshi John et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Histamine in the Nervous System

(2008) Helmut L. Haas et al.   PHYSIOLOGICAL REVIEWS

Adenosine in the tuberomammillary nucleus inhibits the histaminergic system via A1 receptors and promotes non-rapid eye movement sleep

(2008) Y. Oishi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA